Detox Done Right Support Product Kit Ingredients and Product Information

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1 Detox Done Right Support Product Kit Ingredients and Product Information This document contains the ingredients and dosage information provided by Thorne for the products contained in the Detox Done Right Starter Kit (Regular and Chocolate). Medibulk Product Information Colonic bacteria utilize soluble fiber and other undigested carbohydrates as food and subsequently create short-chain fatty acids, which are used by the colonic mucosal cells as fuel. In turn, the short-chain fatty acids liberated by these bacteria can lower colonic ph and shorten transit time in the gastrointestinal tract, which enhances detoxification and reduces the toxic burden on the liver.* Medibulk contains psyllium, pectin, and prune powder as sources of soluble fiber. Anaerobic fermentation of the soluble non-starch polysaccharides in psyllium results in the production of important short-chain fatty acids in the intestines. * One of these fatty acids, butyric acid, is the preferred fuel for colonocytes (mucosal cells of the colon) and provides important support for a healthy colon. * In one study, subjects supplemented with 20 grams of psyllium seed daily for three months exhibited an average increase of butyric acid production of 42 percent, which decreased to pretreatment levels within two months of stopping supplementation. Soluble fiber also has a positive impact in supporting the metabolism of cholesterol and maintaining already healthy blood sugar levels. * Other indications for supplementing with Medibulk include occasional constipation or diarrhea, the need for colon detoxification, soothing of hemorrhoids, and appetite control.

2 *Prior to embarking on a detoxification program it is important to achieve optimal bowel function. Medibulk can speed transit time in the bowel and bind toxins released into the intestines from the liver, preventing their reabsorption.* Begin with 1/2 scoop in 8 ounces of water or dilute fruit juice per night and slowly build up to 2-3 scoops. Follow with at least 8 ounces of water. Ingredients One (11 g) Scoop Contains: Calories 35 Total Carbohydrate 8 g Dietary Fiber 8 g Proprietary Blend: 11 g Psyllium Powder (seed husk) (Plantago asiatica) Prune Powder (fruit) (Prunus domestica) Pectin (from Apple) Other Ingredients: None Note: This product is unflavored and unsweetened. Suggested Use: Take 1 scoop in 8 ounces of water one to three times daily, or begin with 1/2 scoop in 8 counces of water or diluted fruit juice per night and slowly build up to 2-3 scoops. Follow with at least 8 counces of water, or as recommended by a health-care practitioner. Servings Per Container: 20 Statements and Warnings ALLERGY WARNING. This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PURITY. This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product

3 also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY WARNING. If pregnant, consult your health-care practitioner before using this product. INTERACTIONS. There are no known adverse interactions or contraindications at publication date.

4 Solvent Remover Part of Thorne's comprehensive support system for surviving our toxic world for individuals with present or past exposure to solvents enhances liver detoxification* contains antioxidant neuroprotectant nutrients* consider for painters, dry cleaners, construction workers, auto mechanics, beauticians, etc. Product Information: Chemical solvents can be detrimental to the nervous system. Thorne Research's Solvent Remover contains amino acids that support the specific liver detoxification pathways involved in solvent elimination, as well as antioxidant nutrients to help protect nerves from solvent damage.* Individuals exposed to solvents who can benefit from this product include painters, dry cleaners, construction workers, printers, office workers, auto mechanics, manicurists, and beauticians. Other individuals who can benefit from Solvent Remover include those sensitive to paint, glue, and perfume, and persons with food intolerance, poor cholesterol metabolism, and/or fat-soluble vitamin depletion. The amino acids glycine, L-glutamine, and taurine in Solvent Remover enhance the function of the liver pathways involved in solvent detoxification.* N- acetylcysteine increases the production of glutathione, an antioxidant that promotes detoxification.* Alpha-lipoic acid also increases glutathione and is neuroprotective.*

5 Ingredients: Two Capsules Contain: Glycine 300 mg. L-Glutamine 300 mg. Taurine 300 mg. Alpha-Lipoic Acid 100 mg. N-Acetyl-L-Cysteine 100 mg. Other Ingredients: Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide. Suggested Use: Take 2 capsules two to three times daily or as recommended by a health-care practitioner. Servings Per Container: 45 Statements and Warnings: ALLERGY WARNINGS. This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. EXCIPIENT FREE. This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates. PREGNANCY WARNING. If pregnant, consult your health-care practitioner before using this product. INTERACTIONS/CONTRAINDICATIONS. There are no known adverse interactions or contraindications at publication date.

6 Mediclear - Regular Rice protein, pea protein, and accessory nutrients to support liver detoxification* MediClear is a rice and pea protein-based dietary supplement designed to be used: with elimination diets as an adjunct in liver and colon detoxification* to provide a non-allergenic source of protein with a complete weight-reduction program aimed at lower calorie intake and providing adequate protein and nutrient supplementation Product Information: Our external environment has become increasingly more polluted in the last 50 years, causing a greater cumulative toxic burden in humans than ever before. Unavoidable exposure to thousands of toxic chemicals in the environment has delivered up the daunting task of detoxifying and eliminating these substances from our bodies. Added to this are the many internally produced substances (hormones, biochemical metabolites) the body must detoxify on a daily basis. The result is a serious challenge to our organs of elimination, particularly the liver. In addition to this ever-increasing toxic load, the over-consumption of fats and sugars and our reliance on nutrient-depleted vegetables, grains, fruits, and antibiotic- and hormone-laden meats adds to the toxic load while providing inadequate nutrients for many metabolic processes, especially detoxification. The liver carries the greatest share of the detoxification burden, as it is the liver's job to change potentially harmful substances into non-toxic, water-soluble compounds that can be eliminated by the kidneys or intestines. The liver and other tissues participating in the detoxification process must have available the proper nutrient cofactors to efficiently accomplish this task.* In addition, specific botanicals are useful in assisting detoxification by the liver.*

7 What is Phase I/Phase II Liver Detoxification? In phase I of liver detoxification, fat-soluble substances are converted to intermediate metabolites mainly by a group of enzymes called cytochrome p450 enzymes. The intermediate molecules are often more reactive and potentially more toxic than the original substance. Phase II detoxification involves the attachment of other molecules onto these intermediate metabolites to make them non-toxic and water-soluble and allow their elimination via the urine or intestines. MediClear Provides Liver Support* Providing essential nutrient cofactors, while supplying an adequate amount of low-allergenicity protein, can be very beneficial to liver function.* Health-care practitioners know that many challenges to health can arise when a patient's liver is not functioning as it should, including poor digestion, imbalances in intestinal bacteria, and fatigue. MediClear includes beneficial detoxification nutrient cofactors,* as well as an array of extra nutrients and botanicals in powder form that can be added to water, or fruit or vegetable juice, resulting in a pleasant-tasting beverage. Why Rice and Pea Protein? Rice and pea protein are used in MediClear because of their low incidence of allergenicity. It is far more likely for dairy or soy protein to initiate an allergic reaction. Using rice and pea proteins allows you to eliminate most allergenic proteins from the diet, yet maintain high-quality protein intake. Detoxification Cofactors MediClear contains vitamins and minerals necessary for detoxification and liver support.* These nutrients are provided in the most absorbable, best utilized forms, such as calcium and magnesium citrate-malate, pyridoxal 5'-phosphate (active vitamin B6), folinic acid and L-5-MTHF (active forms of folate), methyland adenosylcobalamin (active forms of B12), and UltraChrome (Thorne's patented chromium).*

8 The Difference. MediClear is different than most similar beverage mixes. MediClear contains more protein, fewer carbohydrates, more accessory detox cofactors, special nutrients, and a probiotic for gut health &ndash and it's more affordable than other detox formulas.* Ingredients: Two (49 g) Scoops Contain: Calories 190 Calories from Fat 33 Total Fat 3 g Saturated Fat 1.5 g Cholesterol 0 mg Total Carbohydrates 9 g Sugars 4 g Dietary Fiber 2 g Protein 31 g Vitamin A (3,000 IU from Mixed Carotenes and 2,000 IU as Palmitate) 5,000 IU. Vitamin C (as Ascorbic Acid) 300 mg. Vitamin D (as Vitamin D3) 400 IU. Vitamin E (70 IU from Mixed Tocopherols and 50 IU as d-alpha Tocopherol) 120 IU. Thiamin (as Thiamin HCl) 12 mg. Riboflavin (as Riboflavin 5'-Phosphate Sodium) 5 mg. Niacin (30 mg as Niacinamide and 8 mg as Niacin) 38 mg. Vitamin B6 (as Pyridoxal 5'-Phosphate) 10 mg. Folate (150 mcg as Calcium Folinate and 150 mcg as L-5 Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 300 mcg. Vitamin B12 (25 mcg as Adenosylcobalamin and 25 mcg as Methylcobalamin) 50 mcg.

9 Biotin 150 mcg. Pantothenic Acid (as Calcium Pantothenate) 50 mg. Calcium (as Calcium Citrate-Malate) 300 mg. Phosphorus 295 mg. Magnesium (as Magnesium Citrate-Malate) 150 mg. Zinc (as Zinc Picolinate) 10 mg. Selenium (as Selenomethionine) 70 mcg. Manganese (as Manganese Picolinate) 1.5 mg. Chromium (as Chromium Chelidamate Arginate)* 100 mcg. Molybdenum (as Molybdenum Picolinate) 50 mcg. Potassium (as Potassium Citrate-Malate) 300 mg. Glycine** 1.65 g. Medium Chain Triglycerides (MCTs) 1.5 g. L-Glutamine** 500 mg. L-Lysine (as L-Lysine Monohydrochloride)** 500 mg. Quercetin (water-soluble) 250 mg. Taurine** 110 mg Methyl Sulfonyl Methane (MSM) 100 mg. Bacillus coagulans*** 50 mg. Betaine Anhydrous (Trimethylglycine) 50 mg. N-Acetyl-L-Cysteine** 50 mg. Choline Citrate 30 mg. Glutathione (Reduced)** 25 mg. Green Tea extract (leaf) (Camellia sinensis) decaffeinated 25 mg. Boron (as Boron Picolinate) 100 mcg. Vanadium (as Vanadium Picolinate) 50 mcg. Other Ingredients: Pea Protein, Rice Protein, Pure Cane Molasses, Rice Bran, Silicon Dioxide, SlimSweet (Lo Han fruit extract), and Vanilla and Orange flavoring. SlimSweet is a registered trademark of TriMedica International, Inc.

10 *Thorne's trade name for Chromium (4 oxopyridine,2,6-dicarboxylate, arginate) is UltraChrome. Its use in this product is protected by U.S. Patent No. 5,665,385. **ADDED AMINO ACIDS ***Lactobacillus sporogenes (alternate nomenclature) Camellia standardized to EGCG 40% Suggested Use: For adults and children 12 or more years of age. Mix 2 scoops with 8 ounces of cold water, vegetable or fruit juice, rice milk, or nut milk 1-3 times daily. This product is not a medical food. It is intended to be utilized in conjunction with a complete dietary program. Do not use in diets supplying less than 600 calories per day without complete medical supervision. Servings Per Container: 20 Statements and Warnings ALLERGY WARNING. This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PURITY. This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY WARNING. If pregnant, consult your health-care practitioner before using this product. INTERACTIONS. Folinic acid and 5-methyltetrahydrofolate supplementation is not recommended concurrent with methotrexate cancer therapy, as they can interfere with methotrexate's anti-neoplastic activity; however, these folate sources have not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate. ADDITIONAL WARNING. Gas, bloating, or diarrhea may occur in some individuals taking magnesium supplements. This can occur at varying amounts depending

11 on the individual and resolves when the amount is reduced. Vitamin C can cause diarrhea in some individuals in large doses, which can vary from person to person and resolves when the amount is reduced.

12 Mediclear-SGS - Chocolate Thorne's MediClear Plus formula, enhanced with sulforaphane glucosinolate (SGS) for extended antioxidant support and enhanced phase II liver support* all in a delicious chocolate flavor! standardized curcumin, green tea, and grape seed extracts all complexed with phosphatidylcholine for enhanced antioxidant support* sulforaphane glucosinolate (SGS) for greater liver phase II support and targeted chemoprotection* Product Information Thorne Research is introducing the newest addition to the MediClear line MediClear-SGS! MediClear-SGS provides all the elements of MediClear Plus with the addition of advanced antioxidant and phase II liver support from sulforaphane glucosinolate (SGS).* Plus, MediClear-SGS comes in a great-tasting chocolate flavor. Sulforaphane Glucosinolate and Enhanced Liver Support* In addition to providing a blend of key botanical extracts, nutrients, and nutrient cofactors in an easy-to-use powder formula, MediClear-SGS offers enhanced liver support by adding sulforaphane glucosinolate (SGS) a natural substance from the seeds and sprouts of select broccoli varietals for effective upregulation of the body's natural phase II detoxification enzymes.* SGS is also an indirect antioxidant that provides long-lasting cell protection from free-radical damage days after being consumed.* Each serving of MediClear-SGS contains 30 mg of sulforaphane glucosinolate equivalent to eating 1.2 lbs of broccoli. Detoxification Redefined by Phytosome Technology MediClear-SGS also contains curcumin, green tea, and grape seed extracts in phytosome form for enhanced bioavailability and assured delivery to the

13 tissues.* Phytosomes are specific plant extracts bound to phosphatidylcholine which greatly increases the absorption and blood levels of the desired botanical constituents.* Detoxification Cofactors MediClear-SGS also contains vitamins and minerals necessary for detoxification and liver support.* These nutrients are provided in the most absorbable, bestutilized forms, such as calcium and magnesium citrate-malate, pyridoxal 5'- phosphate (active vitamin B6), folinic acid and L-5-MTHF (active forms of folate), methyl- and adenosylcobalamin (active forms of B12), and UltraChrome (Thorne's patented chromium).* Why Rice and Pea Protein? VegaLite, Thorne's proprietary blend of rice and pea protein, is used in MediClear-SGS. The combination of rice and pea is used because of their low incidence of allergenicity. It is far more likely for dairy or soy protein to initiate an allergic reaction. Using rice and pea proteins eliminates most allergenic proteins from the diet, yet maintains high-quality protein intake. Ingredients: Two Level (28.6 g) Scoops Contain: Calories 145 Calories from Fat 20 Total Fat 2 g Saturated Fat 0 g Trans Fat 0 g Cholesterol 0 mg Total Carbohydrate 8 g Sugars 5 g Dietary Fiber 2 g Protein 23 g

14 Vitamin A (3,000 IU from Mixed Carotenes and 2,000 IU as Palmitate) 5,000 IU Vitamin C (as Ascorbic Acid) 300 mg Vitamin D (as Vitamin D3) 400 IU Vitamin E (70 IU from Mixed Tocopherols and 50 IU from d-alpha Tocopherol) 120 IU Thiamin (as Thiamin HCl) 12 mg Riboflavin (as Riboflavin 5'-Phosphate Sodium) 5 mg Niacin (30 mg as Niacinamide and 8 mg as Niacin) 38 mg Vitamin B6 (as Pyridoxal 5'-Phosphate) 10 mg Folate (150 mcg as Calcium Folinate and 150 mcg as L-5 Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 300 mcg Vitamin B12 (25 mcg as Adenosylcobalamin and 25 mcg as Methylcobalamin) 50 mcg Biotin 150 mcg Pantothenic Acid (as Calcium Pantothenate) 50 mg Calcium (as Calcium Citrate-Malate) 300 mg Magnesium (as Magnesium Citrate-Malate) 150 mg Zinc (as Zinc Picolinate) 10 mg Selenium (as Selenomethionine) 70 mcg Manganese (as Manganese Picolinate) 1.5 mg Chromium (as Chromium Chelidamate Arginate)* 100 mcg Molybdenum (as Molybdenum Picolinate) 50 mcg Sodium (as Sodium Chloride) 64 mg Potassium (as Potassium Citrate-Malate) 300 mg Proprietary Blend** 23 g Pea Protein Isolate Rice Protein Glycine*** 1.65 g Medium Chain Triglycerides (MCTs) 1.5 g L-Glutamine*** 500 mg L-Lysine (as L-Lysine Monohydrochloride)*** 500 mg Curcumin Phytosome **** (Curcuma longa extract (root)

15 Phosphatidylcholine complex) 400 mg Quercetin (water-soluble) 250 mg Taurine*** 110 mg Methyl Sulfonyl Methane (MSM) 100 mg Grape Seed Phytosome **** (Vitis vinifera extract / Phosphatidylcholine complex) 50 mg Green Tea Phytosome **** (Camellia sinensis extract (leaf) /Phosphatidylcholine complex) 50 mg Bacillus coagulans ***** 50 mg Betaine Anhydrous (Trimethylglycine) 50 mg N-Acetyl-L-Cysteine*** 50 mg Choline Citrate 30 mg Sulforaphane Glucosinolate (from Broccoli extract (seed) (Brassica oleracea italica))****** 30 mg Glutathione (Reduced)*** 25 mg Boron (as Boron Picolinate) 100 mcg Vanadium (as Vanadium Picolinate) 50 mcg Other Ingredients: Cocoa, Natural Flavors, Slim Sweet (Lo Han fruit extract), Rice Bran, Evaporated Cane Juice Sugar, Glucose, Stevia (Stevia Extract), Silicon Dioxide. *Thorne's trade name for Chromium (4 oxopyridine,2,6-dicarboxylate, arginate) is UltraChrome. Its use in this product is protected by U.S. Patent No. 5,665,385. **VegaLite, Thorne's trade name for proprietary pea / rice protein blend. ***Added Amino Acids. **** This product uses Indena S.p.A.'s green tea phytosome (Greenselect ), grape seed phytosome (Leucoselect ), and curcumin phytosome (Meriva ). Greenselect, Leucoselect, and Meriva are registered trademarks of Indena S.p.A. ***** Lactobacillus sporogenes (alternate nomenclature). ******The extraction of glucosinolates from cruciferous seeds is protected by U.S. Patent No. 5,725,895. The use of this product is protected by U.S. Patent Nos. 5,968,505 and 5,968,567

16 Contains ingredients derived from soy (phytosomes). Suggested Use: For adults and children 12 or more years of age. Mix 2 level scoops with 10 oz. of water, juice, rice milk, or nut milk one to three times daily or as recommended by your health-care practitioner. This product is not a medical food. It is intended to be utilized in conjunction with a complete dietary program. Do not use in diets supplying less than 600 calories per day without complete medical supervision. Servings Per Container: 20 ALLERGY WARNING. This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. MediClear-SGS contains green tea phytosome, curcumin phytosome, and grape seed phytosome - plant extracts complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in MediClear-SGS. PURITY. This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY WARNING. If pregnant, consult your health-care practitioner before using this product. INTERACTIONS. Folinic acid and 5-methyltetrahydrofolate supplementation is not recommended concurrent with methotrexate cancer therapy, as they can interfere with methotrexate's anti-neoplastic activity; however, these folate sources have not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate. Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research revealed that

17 curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided. OTHER WARNING. This product is intended to be utilized in conjunction with a complete dietary program. Do not use in diets

18 Basic Detox Nutrients Basic Detox Nutrients A comprehensive multiple vitamin-mineral with additional nutrients to aid in detoxification* with highly bioavailable flavonoid phytosomes green tea, curcumin, and milk thistle a unique multiple vitamin-mineral product designed for a toxic world use as part of a complete cleansing program use as a stand-alone product to mitigate exposure to environmental toxins* free of pre-diluted ingredients and hidden preservatives Product Information Basic Detox Nutrients is designed for individuals with environmental toxicity. It can be used within a cleansing program or as a stand-alone product for preventive use. Basic Detox Nutrients is a complete multi vitamin-mineral formulation with higher levels of nutrients commonly found to be deficient in those with chemical overload, as well as those nutrients and botanicals that help the body handle the toxic load,* including: B vitamins: Thiamine (vitamin B1) is essential to restore the body's antioxidant defense - glutathione and lipoic acid.* Thiamine is depleted by chlorinated pesticides and formaldehyde, two ubiquitous toxins. Riboflavin 5'-phosphate (the active form of vitamin B2) helps block free-radical damage by recycling glutathione.* Pyridoxal 5'-phosphate (the active form of vitamin B6) is depleted by many toxic substances, and a vitamin B6 deficiency makes it difficult for the liver to detoxify.* Other important detox nutrients: Magnesium citrate-malate is a well-absorbed form of magnesium, one of the most commonly deficient nutrients in the chemically toxic individual.* Choline is needed for the production of liver detoxification enzymes, N-acetylcysteine increases glutathione levels in the body, MSM provides sulfur for detoxification reactions, and R-lipoic acid is a

19 powerful antioxidant that increases glutathione levels.* Botanical extracts: Green tea extract has potent antioxidant activity.* Milk thistle has proven ability to increase liver glutathione levels and resist liver cell damage from toxins.* Curcumin extract (from turmeric) protects the liver and has been shown to suppress several common chemical toxins.* Green tea, milk thistle, and curcumin are all provided bound to phosphatidylcholine as phytosomes, Greenselect, Siliphos, and Meriva, respectively. This significantly increases the absorption and bioavailability of these flavonoids. Both broccoli extract and dandelion root also enhance detoxification by the liver.* Ingredients: Twelve Capsules Contain: Vitamin A (25,000 IU from Mixed Carotenes and 2,500 IU as Palmitate) 27,500 IU. Vitamin D (as Vitamin D3) 1,600 IU. Vitamin E (as d-alpha Tocopheryl) 400 IU. Vitamin K (as Vitamin K1) 100 mcg. Vitamin C (as Calcium Ascorbate) 1 g. Thiamin (as Thiamin HCl) 200 mg. Riboflavin (as Riboflavin 5'-Phosphate Sodium) 50 mg. Niacin (100 mg as Niacinamide and 30 mg as Niacin) 130 mg. Vitamin B6 (as Pyridoxal 5'-Phosphate) 100 mg. Folate (500 mcg as Calcium Folinate and 500 mcg as L-5 Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 1 g. Vitamin B12 (225 mcg as Adenosylcobalamin and 225 mcg as Methylcobalamin) 450 mcg. Biotin 400 mcg. Pantothenic Acid (as Calcium Pantothenate) 400 mg. Calcium (as Calcium Citrate-Malate) 300 mg. Iodine (as Potassium Iodide) 150 mcg.

20 Magnesium (as Magnesium Citrate-Malate) 500 mg. Zinc (as Zinc Picolinate) 30 mg. Selenium (as Selenium Picolinate) 200 mcg. Manganese (as Manganese Picolinate) 6 mg. Chromium (as Chromium Chelidamate Arginate)* 200 mcg. Molybdenum (as Molybdenum Picolinate) 100 mcg. Potassium (as Potassium Citrate-Malate) 90 mg. Choline Citrate 300 mg. N-Acetyl-L-Cysteine 200 mg. Methyl Sulfonyl Methane (MSM) 100 mg. Silybin Phytosome** (Silybum marianum extract (seed) /Phosphatidylcholine complex) 100 mg. Curcumin Phytosome** (Curcuma longa extract (root) / Phosphatidylcholine complex) 100 mg. Inositol 60 mg. Green Tea Phytosome** (Camellia sinensis extract (leaf) / Phosphatidylcholine complex) 50 mg. R-Lipoic Acid (as Sodium R-Lipoic acid)** 50 mg. Dandelion extract (root) (Taraxacum officinale) 10 mg. Boron (as Boron Picolinate) 3 mg. Vanadium (as Vanadium Picolinate) 100 mcg. Other Ingredients: Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide. *Thorne's trade name for Chromium (4 oxopyridine,2,6-dicarboxylate, arginate) is UltraChrome. Its use in this product is protected by U.S. Patent No. 5,665,385. **This product uses GeroNova Research's Bio-Enhanced R-Lipoic Acid and Indena S.p.A.'s silybin phytosome (Siliphos ), curcumin phytosome (Meriva ), and green tea phytosome (Greenselect ). Bio-Enhanced is a registered trademark of GeroNova Research, Inc. and Siliphos, Meriva, and Greenselect are registered trademarks of Indena S.p.A.

21 Taraxacum PE 4:1. Contains ingredients derived from soy (phytosomes). Suggested Use: Take 6-12 capsules daily or as recommended by a health-care practitioner. Servings Per Container: 30 Statements and Warnings ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. Iodine may occasionally cause an allergic reaction in some individuals. Basic Detox Nutrients contains curcumin phytosome, silybin phytosome, and green tea phytosome plant extracts complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in Basic Detox Nutrients. EXCIPIENT FREE This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates. PREGNANCY WARNING If pregnant, consult your health-care practitioner before using this product. INTERACTIONS/CONTRAINDICATIONS As vitamin K interferes with the effect of anticoagulant drugs (like Coumadin), the concurrent use of these agents should be avoided. Folinic acid and 5-methyl-tetrahydrofolate supplementation is not recommended concurrently with methotrexate cancer therapy, as they can interfere with methotrexate's anti-neoplastic activity; however, these folate sources have not been shown to interfere with the anti-inflammatory activity of

22 methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate. Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research reveals curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided.

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