BIOPRO PRODUCT SALES MATRIX

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1 First MPJ Hemi Implant First MPJ Hallux Rigidus/Limitus implant. 2mm thickness allows for minimal 5 standard sizes Available in cobalt chrome & titanium Available in porous & non-porous coated Barbed stem provides secure fixation Minimum bone preserves the FHB Higher patient satisfaction compared to arthrodesis 1 Long term survivorship 2 Improved motion 3 Maintains bone stock A perspective on MTPJ implant arthroplasty Study: Arthrodesis Versus (2015) Study: 279 patients Townley/Taranow (1994) Competition matrix Wright Metal Hemi AnaToemic Vilex 1 st CHI Hemi ReFlexion Arthrosurface HemiCap Cartiva Joint Lesser MPJ Hemi Implant Lesser MPJ implant. 2mm thickness allows for minimal 9 standard sizes Cannulated and non-cannulated options Minimum bone Maintains motion Multiple sizes match patient anatomy Freiberg s Infraction Post-traumatic arthritis A perspective on MTPJ implant arthroplasty Study: Treatment of Freiberg's Infraction with the Titanium Hemiimplant (2004) Vilex Lesser CHI Arthrosurface HemiCap Cartiva Digital Compression Screw Lag screw for hammertoe fixation. 1.5mm and 1.8mm diameters 20mm to 55mm lengths (5mm increments) Low profile head reduces chance of irritation Buried fixation reduces chance of infection Compressive force increases viability In office removal Hammertoe fixation Case report Stryker SmartToe Vilex HammerFUZE ExtremiFuse Wright TENFUSE and PRO-TOE 1 Timothy Voskuijl, MD, Ron Onstenk, MD. Operative Treatment for Osteoarthritis of the First Metatarsophalangeal Joint: Arthrodesis Versus. The Journal of Foot & Ankle Surgery xxx (2015) Townley, MD, Taranow, DO. A metallic hemiarthroplasty resurfacing prosthesis for the hallux metatarsophalangeal joint. Foot & Ankle International 1994;15(11): Christine C. Salonga, DPM, David C. Novicki, DPM, FACFAS, Martin M. Pressman, DPM, FACFAS, D. Scot Malay, DPM, MSCE, FACFAS. A Retrospective Cohort Study of the BioPro Prosthesis. The Journal of Foot & Ankle Surgery 49 (2010)

2 Stainless steel Nextremity Hammertoe Depuy HammerLock Horizon Subtalar Subtalar Joint Arthroereisis Implant Smooth lateral edge minimizes further arthrosis and sinus tarsitis Tapered edge ensures stability Conservative approach to flatfoot Minimally invasive Easily removed Flatfoot treatment in pediatrics and adults Posterior tibial tendon dysfunction Study: Symptomatic flexible flatfoot in adults: subtalar arthroereisis (2015) ProStop Talar- Fit Vilex TOV Wright Futura HyproCure Tendon Anchor System Rigid toothed titanium anchor for soft tissue fixation to bone. One and two-hole design allows for a variety of procedures Blunt teeth to prevent over Offset teeth engage multiple tendon bundles Low profile reduces implant prominence Earlier ambulation due to improved pullout strength 4 Speed of application reduces OR time Sterile packaging reduces sterilization costs Tendon transfers for drop foot Haglunds procedure Kidner procedure Jones procedure Young s tenosuspension Hibbs procedure Lateral ankle stabilization Clinical outcome report (2017) PRESENT CME lecture Kent State Pull Out Study CorkScrew FASTak SpeedBridge Wright G-Force Suture anchors Interference screws Memory Staple Nitinol staple for bone to bone fixation. 17 standard sizes 6 step-staple sizes S-Bridge allows for more uniform Uniform aids process. Fast and easy insertion Akin Osteotomies Hallux IP Fusion Hallux MPJ Fusion Lesser PIPJ Fusion Austin, Youngswick, Reverdin Bunionectomies Cotton Procedure Stryker Easy Clip Wright Charlotte InstaFix Vilex Nitinex Depuy SPEED 4 Data on file

3 Lapidus Procedure. Talonavicular Fusion Calcaneal Cuboid Fusion Dwyer Osteotomy DIP Fusion PIP Fusion MCP Fusion Cannulated Screws (HBS/Go- EZ) Titanium cannulated lag screws for bone to bone fixation. 2.5mm to 6.5mm headed lag screws 2.5mm & 3.0mm headless screws Sterile packed Sharp cutting teeth reduce insertion force Small bone fixation Cannulated Screws Clover Staple Clover shaped nitinol staple for small bone s. Low profile eliminates impingement Teeth on legs to prevent back out 3 and 4-leg designs with 9 sizes of each available Minimal maximizes mass Constant centralized aids in successful Ability to monitor site Four Corner Fusions STT Fusions Radioscapholunate Fusions Case report: Limited Wrist Fusion Using a New Memory Staple (2004) ASSH Poster Presentation (2017) Two-Legged Staples Cannulated Screws AcuMed Hub Cap TriMed Fusion Cup Stryker 4Fusion Modular Thumb Implant Modular implant for the treatment of CMC joint arthritis. Modular design offers better trapezial and metacarpal fit Varus angle stem avoids dislocation Ti Plasma sprayed stem allows for bone-in growth Conservative approach over LRTI Improves grip strength 6 Maintains cosmetic appearance 6 CMC joint arthritis Study: A Promising Thumb Basal Joint for Treatment of Trapeziometacarpal Osteoarthritis (2012) AAOS Presentation Faillace, MD (2017) Skeletal Dynamic Stablyx Integra PyroCarbon (NuGrip) LRTI procedure

4 Available in cobalt Clinically proven 5 chrome and titanium Accu-Cut Osteotomy Guide System Distal Osteotomy cut guides for treatment of Hallux Valgus. Tight tolerances between guide slots Two-point fixation of guide creates stable platform Sterile procedure kits Precise, repeatable cuts Multiple procedure options Chevron/Austin Youngswick Reverdin-Gerbert Long-Arm Chevron DMAA/PASA correction Scarf Study: Evaluation of surgical experience and the use of an osteotomy guide on the apical angle of an Austin osteotomy (2008) K-wires Reese Cutting Guides Freehand Effi+Pro Sterile packed distraction and device. 100mm of distraction or Sterile packed with mounting pins Linear distraction versus traditional arch Improved stability Precise fracture reduction Radiolucent Talonavicular Calcaneal-cuboid Subtalar Lapidus procedure Flatfoot reconstruction Ankle Ankle scope Fracture reduction Opening wedge procedures Surgeon interview Surgical video Traditional distractors Fasciotome One-sided blade with T-handle. Sharp one-sided blade.0062 diameter Minimally invasive Better control Durable design Less scarring Tenotomies Percutaneous Fasciotomies Scalpels 5 Pritchett, J. W., & Habryl, L. S. (2012). A Promising Thumb Basal Joint for Treatment of Trapeziometacarpal Osteoarthritis. Clinical Orthopaedics and Related Research, 470(10),

5 Break-Out Tool for the removal of broken/stripped cannulated screws. Sizes ranging from.035 to 2.0mm cannulation AO quick connect Easy screw removal Minimal bone disturbance Cannulated screw removal ReBOSSIS Biosynthetic scaffold with handling characteristics of cotton. Composed of b- TCP, CaCO3, Silicon and PLLA Moldable and highly absorbent Maintains integrity during placement Elastic properties enhance bone to graft interface Non-structural bone voids Animal Study Bone Chips Pastes/Putties Orthofix Trinity PalinGen/Promatrx/InovoFlo Amniotic membrane and fluid. PRODUCT MATRIX) PRODUCT MATRIX) PRODUCT MATRIX) Amniotic membrane studies Reimbursement guide MiMedx Amniox BioD Osiris Wright Vivex