CURRICULUM VITAE June 2016

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1 CURRICULUM VITAE June 2016 PERSONAL DETAILS NAME: Jan de Vos (Johannes Nicolaas) NATIONALITY: South African Citizen DATE OF BIRTH: 30/10/1955 ADDRESS: Suite 3, 546 Wilgers Medical Consulting Rooms, 546 Denneboom Road, Pretoria, South Africa POSTAL ADDRESS: P O Box 74813, Lynnwood Ridge, Pretoria, South Africa, 0040 TELEPHONE: +27(0) /6 MOBILE PHONE: +27(0) QUALIFICATIONS PRIMARY DEGREE: SPECIALIST DEGREE: M.B.Ch.B. 1980, University of Pretoria, South Africa M.Med. (Orth) 1991, University of Pretoria, South Africa, Orthopaedic Surgery HIGHLIGHTS OF CAREER Obtaining of MBChB degree in 1980 Obtaining of MMed degree in 1991 Smith and Nephew Travelling Fellow 1991 George Dommisse Prestige Award Best Registrar UP. President of the South African Orthopaedic Association: Sept 2013 Sept 2014 President Elect of the South African Arthroplasty Society April Director of Wilgers Private Hospital in Pretoria (for 14 years) CURRENT EMPLOYMENT Since April 1992 practicing as an Orthopaedic Surgeon at Wilgers Hospital, Pretoria, South Africa in a solo private practice. From February 2014 I was joined by Dr T Monni as an associate. MEDICAL REGISTRATION Health Professions Council of South Africa (MP ) PREVIOUS EMPLOYMENT INTERNSHIP: 1981, Nelspruit Hospital, South Africa /2

2 -2- PRIVATE PRACTICE: MEDICAL OFFICER: REGISTRAR: January 1982 June 1986, Secunda, South Africa as General Practitioner July 1986 December 1986: Kalafong Hospital, Pretoria January 1987 December 1991: Registrar Department of Orthopaedic Surgery, University of Pretoria Head of Department: Prof. RP Gräbe CONSULTANT: December 1991 July 1992 Department of Orthopaedic Surgery, University of Pretoria and HF Verwoerd Hospital, Pretoria Head of Department: Prof. RP Gräbe PRIVATE PRACTICE: an Orthopaedic Surgeon. Since April 1992 part-time and from July 1992 full-time as TRAINING Post-graduate training was done at the HF Verwoerd, No 1 Military and Kalafong Hospitals at Pretoria. The respective heads of the departments of Orthopaedic Surgery were Proff RP Gräbe and A. de Klerk. The training period was from July 1986 until December From December 1991 until July 1992 I worked as a consultant at HF Verwoerd Hospital, Pretoria. ACADEMIC AWARDS 1. Smith & Nephew Travelling Fellowship National Award as Orthopaedic Registrar. 2. George Dommisse Prestige Award University of Pretoria Orthopaedic Award for Best Registrar. EXPERIENCE AND INTEREST Invaluable experience gained as a private general practitioner. Practiced in a fairly rural area. Vast experience in orthopaedic surgery gained as registrar. Since entering private practice the emphasis has shifted from trauma to almost exclusively elective surgery. My main interest is hip, knee and shoulder surgery, both arthroscopic surgery and arthroplasty. Director Wilgers Private Hospital (14 years) MEMBERSHIP -SAOA: South African Orthopaedic Association Honorary Treasurer September 2009 September 2013 Second Vice President 2012 (Sept 2011-Sept 2012)

3 -3- /3 -SAOA: -SAMA: -SAKS: -SAAS: First Vice President 2013 (Sept 2012 Sept 2013) President Sept 2013 Sept 2014 Immediate Past President Sept September 2015 Gauteng North and Limpopo Branch Chairman South African Medical Association South African Knee Society Treasurer and Secretary South African Arthroplasty Association President-Elect April ISHA: International Society of Hip Arthroscopy (2012) -SASHA: South African Society of Hip Arthroscopy (2011) Secretary PAPERS PRESENTED INTERNATIONALLY 1. Trauma Symposium in Barcelona, Spain, November 2001: Unusual humeral fracture. 2. Oral Anticoagulation: Windhoek, Namibia: February Oral Anticoagulation: Swakopmund, Namibia: February Chinese Orthopaedic Association s Annual Congress in Beijing, China, November 2012: Keynote Speaker: Thromboprophylaxis in Major Lower Limb Surgery. 5. Chinese Orthopaedic Association s Annual Congress in Beijing, China, November 2012: World Orthopaedic Alliance Conference: Access to Quality Healthcare; South Africa s Public Healthcare Policy Challenges and Opportunities. 6. British Orthopaedic Associations Congress October 2013, Birmingham, UK. : The painful, stiff knee after a knee replacement. 7. Australian Orthopaedic Associations Annual scientific meeting: October 2013, Darwin, Australia: South Africa s Perspective on Thromboprophylaxis in knee replacement surgery. 8. New Zealand Orthopaedic Associations annual congress, Nelson, New Zealand, October 2013: The Anatomy and Function of the Labrum of the Hip. 9. Combined BOA and EFORT meeting, London, UK, June 2014: Cementing Techniques in Knee Arthroplasty. 10. Combined BOA and EFORT meeting, London, UK, June 2014: The Expected Avalanche in Musculoskeletal Care. 11. Combined AOA and COA meeting, Montreal, Canada, June 2014: The Size and Shape of the Workforce. 12.American Academy of Orthopaedic Surgery (AAOS) Annual conference, Las Vegas, USA, March 2015: Symposium on: The Musculoskeletal Timebomb Time for Action, and my topic was : Cost Effective Orthopaedics in Developing Countries is essential for All PAPERS PRESENTED IN SOUTH AFRICA 1. The 37 th SAOA Annual Congress, September 1991 (Johannesburg): Compartmental Syndrome of the Foot A Proposed Surgical Approach

4 -4- /4 2. The 49 th SAOA Annual Congress, September 2003 (Cape Town): An Alternative to Allogenic blood transfusion: Haemoglobin-basis Oxygen Carrier 3. Total Hip and Total Knee Revision Course, October 2003 (Cape Town): Evaluation and Treatment of the Painful Replaced Knee 4. Paper presented as a Smith Nephew Travelling Fellow: Compartmental syndrome of the foot (all seven major universities of South Africa) Paper presented as a Smith Nephew Travelling Fellow: Surgical Treatment for Ulnar Nerve Palsy No 1 Military Hospital s Experience ((all seven major universities of South Africa) The 18 th Biennial Arthroplasty Congress: Patello-femoral Arthroplasty, April 2005, Drakensberg, South Africa 7. Knee Society Congress: Patello-femoral Arthroplasty, October 2005, Kwa- Maritane, South Africa 8. The Valgus Knee in Knee Arthroplasty, June Winter University Symposium, Natal, South Africa 9. Total Knee Replacement: Painful Stiff Knee Postoperative; July Midrand 10. LCS Knee: Registrars Symposium, November Shoulder impingement syndrome, May DBC South Africa. 12. Pretoria Academic Hospital: Registrars Workshop, July 2007: Meniscus repair Bankart repair ACL reconstruction 13. The 53 rd Annual SAOA Conference September 2007: Mobile Bearing in Total Knee Arthroplasty 14. LCS Complete Knee: Workshop and Surgical Technique & Dry Bone Workshop June Hip Arthroscopy Cadaver Workshop, Cape Town, September Pretoria Academic Hospital: Registrars Workshop, February 2009; Meniscus Repair 17. SAKS Meeting, August 2009, Patellofemoral Pathology, Drakensberg Sun, South Africa 18. The 55 th Annual SAOA Congress September Johannesburg. Mobile Bearing Prosthesis in TKA: Practical Tips and Tricks in MB-TKA. 19. The 56 th Annual SAOA Congress Sept Drakensberg. Revision TKA with Sleeves and Stems. 20. Oral Anticoagulation: Windhoek, Namibia: February Oral Anticoagulation: Swakopmund, Namibia: February Smith & Nephew Cadaver Workshop Knee and Shoulder Arthroscopy, University of Bloemfontein, February Smith & Nephew Cadaver Workshop Hip Arthroscopy, Tygerberg Laboratory, Cape Town, June The 21 st Biennial South African Arthroplasty Congress: The Difficult primary Total Hip Replacement: Cape Town 6 April The 57th Annual SAOA Congress, Sun City, September 2011: Chairman of the Organising Committee.

5 26. Total Knee Replacement: Painful Stiff Knee; Hip and Knee Master class, Zimmer, Johannesburg, South Africa, October Oral Anticoagulation, Bayer, Johannesburg South Africa, February 2012 /5 28. Extra Large Metal on Metal bearing: Revision Hip Master class, Zimmer: Cape Town, South Africa, March Oral Anticoagulation, Bayer, Cape Town, South Africa, February GP s Forum Life Wilgers Hospital Hip Pain: Evaluation and Preservation Surgery, May The 58 th Annual SAOA Congress, Durban, September 2012: Anticoagulation: where are we today? 32. Hip Arthroscopy: Steve Biko Hospital, Post-Graduate Meeting, Pretoria; 29/01/ Introduction to the South African National Joint Registry: Cape Town 07/02/2013. Hip Arthroplasty Master class Zimmer. 34. Academic Faculty: Cape Town 07/02/2013. Hip Arthroplasty Master class Zimmer. 35. The Anatomy and Function of the Hip Labrum: First International South African Society of Hip Arthroscopy Congress: Cape Town 2/5/ Sub-spine hip Impingement: First International South African Society of Hip Arthroscopy Congress: Cape Town 2/5/ The 59 th Annual SAOA Congress: Sun City;The use of cement in TKA. September The 59 th Annual SAOA Congress: Sun City; Report on the National Joint Registry. September Clinical Evaluation of the Patient with a Painful TKA: Johannesburg. Zimmer Masterclass 30 January The Special Investigations of a Painful TKA: Johannesburg. Zimmer Masterclass 30 January Proper Placement of the Acetabular Prosthesis in THA: Johannesburg. Zimmer Masterclass 31 January The 60 th Annual SAOA Congress: Cape Town; Presidential Valedictory Address. 43. Cementing Techniques in TKA: Cape Town; The Knee; From A-Z, Smith and Nephew; February DVT prophylaxis in TKR: Cape Town; The Knee; From A-Z, Smith and Nephew; February The stiff painful knee post TKR: Cape Town; The Knee; From A-Z, Smith and Nephew; February Periprosthetic Femoral Fractures in Total Hip Replacement Surgery: Wild Coast Sun. Hip Revision Masterclass; April The 23 rd Biennial South African Arthroplasty Society s conference: Update on the SANJR 48. Theatre Set-up and Arthroscopic Anatomy of the Hip: 2 nd Biennial Conference of the South African Society of Hip Arthroscopy (SASHA): Cape Town; 1 May The Results of Hip Arthroscopy: : 2 nd Biennial Conference of the South African Society of Hip Arthroscopy (SASHA): Cape Town; 1 May

6 50. Bone loss and Metaphyseal fixation in Revision TKR: Cape Town, DePuySynthes Institute, August / World Combined Orthopaedic Conference (COMOC) held in Cape Town 13 April 2016: I was part of the Symposium: The International Musculoskeletal Time Bomb: Better outcomes Lower cost My personal presentation: Cost Effective Orthopaedics in Developing Countries is Essential for All PUBLICATIONS. 1. The Journal of Bone and Joint Surgery, British Edition Volume 74-B, 1992,Orthopaedic Proceedings Supplement II. Compartment Syndrome of the Foot 2. SA Orthopaedic Journal Vol 3 No1, February Expert Opinion on Published Articles : - Autologous Blood Transfusion after Total Knee Arthroplasty(Jul. Arthroplasty 18(3) Apr 2003) - The Value of White Blood Cell Counts before Revision Total Knee Arthroplasty (Jul. Arthroplasty 18(8) Dec 2003) - Mortality Following Primary Total Knee Arthroplasty (JBJS 85A(3) March 2003) 3. Money makes the world go round Editorial in The SA Orthopaedic Journal 2014, Vol 13 (1). RESEARCH 1. Principal Investigator: HEM-0115: A multicenter, randomized, single-blind, red blood cell-controlled, parallel-group study to evaluate the effect on allogenic red blood cell use and the safety of room temperature stable Hemoglobinbased Oxygen Carrier-201 (HBOC-201) when administered therapeutically and peri-operatively in orthopaedic surgery patients who have not received erythropoietin in THA and TKA patients nor undergone pre-operative autologous blood donation ( ) 2. Surgical Approaches to the Foot with Compartmental Syndrome ( ) 3. Two Prospective International Studies: : Record 2 Study: Regulation of Coagulation in Orthopaedic Surgery to prevent DVT and PE, controlled, double-blind, randomized study of Bay in the Extended Prevention of VTE in Patients undergoing Elective Total Hip Replacement 4. Record 3 Study: Regulation of Coagulation in Orthopaedic Surgery to prevent DVT and PE, controlled, double-blind, randomized study of Bay in the Extended Prevention of VTE in Patients undergoing Elective Total Knee Replacements.

7 /7 COURSES AND CONFERENCES ATTENDED 2004 June Hip Resurfacing, March Cape Town, South Africa 2. Uni-compartmental Knee Arthroplasty, July Oxford, U.K. 3. Hip Resurfacing, August Pretoria th SAOA Annual Congress, September Pretoria 5. Minimal Invasive Hip Surgery, September Durban 6. Ci - total Knee and Uni-compartmental Knee Arthroplasty, November Hamburg, Germany 7. Current Concepts in Joint Replacement Surgery, December 2004, Orlando, USA th Biennial Arthroplasty Congress, April Drakensberg, South Africa 9. Winter University : Arthroplasty, June Durban, South Africa 10. Hip Arthroscopy Course, September San Francisco, U.S.A 11. Hip Arthroscopy: Visitation Dr. T Byrd, September Nashville, U.S.A. 12. Intelligent Hip Surgery Course, September 2005, Brussels, Belgium 13. Advanced Arthroscopy Shoulder Course, November Liverpool, U.K. 14. The Clinical Challenge of Sepsis, February Pretoria. 15. Certificate of Competence: Good Clinical Practice, March University of Witwatersrand Clinical Research 16. Shoulder Arthroscopy Course, April Cape Town 17. Hip Arthroscopy Course, April Midrand 18. Finance for Healthcare Professionals, May Johannesburg 19. Mini Symposium: Hip and Knee Arthroplasty, June Pretoria 20. ESSKA, May Innsbruck, Austria 21. Intelligent Knee Surgery, May Interalpen, Austria th Biennial Annual Arthroplasty Congress, April Drakensberg, South Africa 23. Clinical Lectures DBC, May 2007, Pretoria 24. Spinal and Shoulder Rehabilitation Seminar, May University of Free State 25. ISAKOS May Florence, Italy 26. American Academy of Orthopaedic Surgeons: 2007 Bi-annual Congress, International Society for Arthroscopy 27. Smith & Nephew, Knee and Shoulder Workshop July Orthomedics, Mobile Bearing in Total Knee Arthroplasty Workshop September Smith & Nephew, European Centre for Knee Research, Leuven, Belgium Journey Knee October Prof J Bellemans 30. Dr. Mark Philippon: Hip Arthroscopy: Steadman Hawkins Clinic, Vail, Colorado USA April South African Academy of Family Practitioners: Medical Legal Issues, Wilgers Hospital April Dr. Ludwig Seebauer: Shoulder Surgery, München, Germany June 2008

8 33. LCS Complete Instructional Course, Oslo Norway June LCS Complete Knee Workshop and Surgical Technique & Dry Bone Workshop June South African Academy of Family Practitioners: Sepsis in Orthopaedic patients August /8 36. SAKS Annual meeting August 2008, Stellenbosch, Cape Town th SAOA Annual Congress September 2008, Cape Town 38. South African Orthopaedic Sports Medicine Conference on Hip Arthroscopy, Cape Town, South Africa, September South African Orthopaedic Sports Medicine Conference Cadaver workshop on Hip Arthroscopy, Cape Town, South Africa, September SAOA, Gauteng and Limpopo meeting, Pretoria, South Africa, February th Biennial SAAS congress, Sun City, March ISAKOS 7 th Biennial Congress April 2009, Osaka, Japan 43. EFORT 10 th Congress June 2009, Vienna, Austria 44. SAOA, Pretoria meeting June Smith & Nephew Workshop: Development in knee surgery, June Orthomedics: Revision Hips Novel Solution Meeting, August SAOA, Pretoria meeting August SAKS Annual Meeting, Patella Femoral Symposium, August The 55 th Congress of South African Orthopaedic Association, Drakensberg South Africa, September Medacta International South Africa, 1 st World Conference on Anterior Hip Approach, Zurich, Switzerland, September Prof. K. Soballe, Pelvic Osteotomies, Denmark, Sweden, September SAOA, Bloemfontein meeting, December SAOA, Gauteng North Branch Meeting, February DePuy Institute, Specialized Topics in Revision Knee, Hamburg, Germany March Orthomedics, Revision Knee Arthroplasty WebEx, March 2010, Pretoria, South Africa 56. SAOA 56 th Annual Congress, Feather Market Centre, South Africa September SAKS Annual Knee Conference: Port Elizabeth, South Africa. September The 21 st Biennial South African Arthroplasty Association Congress: Cape Town, South Africa April DePuy Institute, The 3 rd Revision Meeting the Challenge, Cape Town International Convention Centre, Cape Town, South Africa, April ISAKOS 8 th Biennial Congress, Rio de Janeiro, Brazil, May Smith & Nephew Hip Arthroscopy Cadaveric Workshop, Tygerberg Laboratory, Cape Town, South Africa June Smith & Nephew Hip Arthroscopy, York, August ISHA Scientific Annual Meeting, Paris, France, October Zimmer, Extreme TMT Meeting, Oxford, England, October SAOA 57 th Annual Congress, Sun City, September Zimmer, Hip and Knee Master class, Johannesburg, South Africa, October Zimmer, Hip Master class, Cape Town, South Africa, March 2012

9 ! 68. Zimmer, Interactions Meeting Primary Knee Arthroplasty, Berlin, Germany, April Smith & Nephew: Knee Arthroscopy Seminar Dr C Brown, Durban South Africa, June SAOA 58 th Annual Congress, Durban, September Chinese Orthopaedic Association 7 th Congress, Beijing, China, November / Bioskills Hip Course; Cape Town 30-31/01/2013; Zimmer. 73. Master class Hip Arthroplasty; Cape Town 7-8/2/2013; Zimmer 74. The Second International Society of Joint Registers (ISAR) Congress: Stratford-upon-Avon, UK. : June SAOA 59 th Annual Congress, Sun City, September British Orthopaedic Associations Congress October 2013, Birmingham, UK. 77. Australian Orthopaedic Associations Annual scientific meeting: October 2013, Darwin, Australia 78. New Zealand Orthopaedic Associations annual congress, Nelson, New Zealand, October Zimmer, Knee Master class, Johannesburg, South Africa, January 201/ Zimmer, Hip Master class, Johannesburg, South Africa, January British Orthopaedic Associations Congress October 2013, Birmingham, UK. 82. AAOS, New Orleans, USA, April Combined BOA and EFORT meeting, London, UK, June Combined AOA and COA meeting, Montreal, Canada, June SAOA 60 th Annual Congress, Cape Town, September ISHA Scientific Annual Meeting, Rio de Janeiro, Brazilia, October South African Knee Society Meeting: Cape Town, February The Knee from A-Z: Cape Town, February AAOS Annual Conference, Las Vegas, March nd Biennial Conference of the South African Society of Hip Arthroscop (SASHA): Cape Town; 1 May Cape Town, DepuySynthes Institute, August 2015; Unicompartmental Knee Arthroplasty. 92. Cape Town, DepuySynthes Institute, August 2015; Primary Knee Arthroplasty. 93. Cape Town, DepuySynthes Institute, August 2015; revision knee Arthroplasty. 94. COMOC April 2016, Cape Town, SA 95. EFORT Congress June 2016, Geneva, Switzerland. Jan de Vos

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