Curriculum Vitae. Personal information. Work experience. First name / Surname Martina BOCCHETTA

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1 Curriculum Vitae Personal information First name / Surname Martina BOCCHETTA mbocchetta@fatebenefratelli.it Nationality Italian Place and Date of birth Bergamo (Italy), May, 9 th 1986 Gender female Work experience Dates Occupation or position held Main activities and responsibilities Name and address of employer Dates Occupation or position held Main activities and responsibilities Name and address of employer March 2014 to date Honorary Research Assistant (Visiting PhD Student) Development of a segmentation protocol for the hypothalamus for studying its morphology in a sample of patients with behavioral frontotemporal lobar degeneration. Dementia Research Centre, University College London, Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom (Head: Nick Fox). September 2011 to date Researcher Involved in the Alzheimer s Association funded project A harmonized protocol for hippocampal volumetry: an EADC-ADNI effort : manual segmentation of hippocampus and its subunits volumetry on magnetic resonance image (MRI); collaboration in drafting papers and scientific reports; management of international contacts. Project Coordinator of the study Italian Network for autosomal dominant Alzheimer s disease and frontotemporal lobar degeneration and collaborating within the project GENetic Frontotemporal Dementia Initiative: a new multi-centre platform for the study of frontotemporal lobar degeneration. Tracer of hippocampal volumetry for assessing patients afferent to the Translational Outpatient Memory Clinic. Collaborator for monthly newsletters for Gender Medicine and weekly newsletter InfoAlzheimer on Alzheimer s and other dementia update for Italian practitioners and neurologists. Reviewer for International Journal of Alzheimer's Disease, Neurobiology of Aging, Alzheimer's & Dementia and Journal of Affective Disorders. LENITEM - Laboratory of Epidemiology Neuroimaging and Telemedicine IRCCS - San Giovanni di Dio Fatebenefratelli, Brescia (Italy) (head: Giovanni B. Frisoni) Occupation or position held Main activities and responsibilities Name and address of employer Occupation or position held Main activities and responsibilities Name and address of employer Dates September August 2011 Post-Graduate Fellow and Part-time Research Assistant Collaborator on the study of basal ganglia morphology through Radial Distance Mapping (RDM) technique on early and late-onset Alzheimer s Disease patients. Research Assistant for the Alzheimer s Association funded project A harmonized protocol for hippocampal volumetry: an EADC-ADNI effort. LENITEM - Laboratory of Epidemiology Neuroimaging and Telemedicine IRCCS - San Giovanni di Dio Fatebenefratelli, Brescia (Italy) (head: Giovanni B. Frisoni) Dates October 2009 August 2010 Academic Internship and Part-time Research Assistant Trainee in post-processing neuroimaging programmes, manual segmentation of basal ganglia volumetry on MRI and learning of RDM technique for the study of subjects with psychopathy. Research Assistant for the Alzheimer s Association funded project A harmonized protocol for hippocampal volumetry: an EADC-ADNI effort. LENITEM - Laboratory of Epidemiology Neuroimaging and Telemedicine IRCCS - San Giovanni di Dio Fatebenefratelli, Brescia (Italy) (head: Giovanni B. Frisoni) Page 1/8 - Curriculum vitae of

2 Education and training Dates Title of qualification awarded Title of qualification awarded Title of qualification awarded Principal subjects/occupational skills covered November 2012 to date PhD student in Neuroscience University of Brescia (Italy), Faculty of Medicine, School of Biomedical Sciences and Translational Medicine (tutors: M.C. Missale, Prof.; G.B. Frisoni, Prof.) Dates September 2008 June 2010 Master s Degree in Neuroscience and Neuropsychological Rehabilitation (110/110 cum laude) Graduation Thesis: Psychopathy and basal ganglia morphology, (tutors: A. Facoetti, Prof; M. Boccardi, PhD) University of Padua (Italy), Faculty of Psychology Dates September 2005 July 2008 Bachelor s Degree in Cognitive Psychology and Psychobiology (110/110 cum laude) Graduation Thesis: Identification of Cholinergic Pathways on Magnetic Resonance Images for the Study of Human Brain with Neuroimaging Techniques, (tutors: M. Folin, Prof; M. Boccardi, PhD; M. Pievani, PhD) University of Padua (Italy), Faculty of Psychology Dates October 2007 June 2008 Academic Internship: trainee in post-processing neuroimaging programmes, manual segmentation of intracranial volumetry and localization of cholinergic nuclei on MRI. LENITEM - Laboratory of Epidemiology Neuroimaging and Telemedicine IRCCS - San Giovanni di Dio Fatebenefratelli, Brescia (Italy) (head: Giovanni B. Frisoni) Dates September 2000 July 2005 Title of qualification awarded High School Scientific Degree (100/100) English PET and partial* FCE Certificate (Listening and Speaking) (* due to examiners impossibility to complete the Reading and Writing exam session) Personal skills and competences Scientific High School Lorenzo Mascheroni in Bergamo (Italy) Mother tongue Italian Other language Self-assessment Understanding Speaking Writing European level (*) Listening Reading Spoken interaction Spoken production English B2 Independent User C1 Proficient user B2 Independent User (*) Common European Framework of Reference for Languages B2 Independent User B2 Independent User Social skills and competences Organisational skills and competences Good interpersonal and cooperative skills. I work in a multi-disciplinary environment with a team of psychologists, neurologists, mathematicians, biologists and physicians and we are open to constant mutual exchanging, sharing and comparing of opinions, experiences and knowledge. Good organisational skills, in particular in managing different tasks, in adapting and adhering to timeschedule and deadlines. Within the project A harmonized protocol for hippocampal volumetry: an EADC-ADNI effort, I am responsible for international contacts management and I contributed to the organization of the international webinar meetings (taken place during AAN and AAICAD congresses). Page 2/8 - Curriculum vitae of

3 Technical skills and competences Computer skills and competences Other skills and competences Driving licence Expert in manual segmentation on magnetic resonance images (MRIs) of intracranial and other structure volumetry (hippocampus, caudate nucleus, nucleus accumbens, putamen); Image computational analysis with Radial Distance Mapping (RDM) and Voxel-Based Morphometry (VBM) techniques; visual assessment of medial temporal lobe atrophy through Scheltens s MTA Scale; visual assessment of white matter lesions through Wahlund s scale. Competence with Microsoft Office programmes (Word, Excel, PowerPoint); basic notions of Statistical software (R, SPSS, PS and Prism); competence with neuroimaging programmes and tools (MRIcro, Display, MultiTracer, ImageJ, RDM) and graphics programmes (IrfanView and GIMP); sufficient ability to write simple scripts in Unix language. Competence with RefWorks, Pubmed, ISI Web of Knowledge and GoToWebinar. Keen on music, photography and reading. I played volleyball on an agonistic level for 10 years. Italian B licence. Car owner. Page 3/8 - Curriculum vitae of

4 Additional information Publications: Full Papers: Bocchetta M, Galluzzi S, Kehoe PG, Aguera E, Bernabei R, Bullock R, Ceccaldi M, Dartigues JF, de Mendonça A, Didic M, Eriksdotter M, Félician O, Frölich L, Gertz HJ, Hallikainen M, Hasselbalch SG, Hausner L, Heuser I, Jessen F, Jones RW, Kurz A, Lawlor B, Lleo A, Martinez-Lage P, Mecocci P, Mehrabian S, Monsch A, Nobili F, Nordberg A, OldeRikkert M, Orgogozo JM, Pasquier F, Peters O, Salmon E, Sánchez-Castellano C, Santana I, Sarazin M, Traykov L, Tsolaki M, Visser PJ, Wallin AK, Wilcock G, Wilkinson D, Wolf H, Yener G, Zekry D, Frisoni GB. The Use of Biomarkers for the Etiologic Diagnosis of MCI in Europe: an EADC Survey. (accepted for publication in Alzheimer's & Dementia on June 17, 2014). Frisoni GB, Jack CR, Bocchetta M, Bauer C, Frederiksen KS, Liu Y, Preboske G, Swihart T, Blair M, Cavedo E, Grothe MJ, Lanfredi M, Martinez O, Nishikawa M, Portegies M, Stoub T, Ward C, Apostolova LG, Ganzola R, Wolf D, Barkhof F, Bartzokis G, DeCarli C, Csernansky JG, detoledo-morrell L, Geerlings MI, Kaye J, Killiany RJ, Lehéricy S, Matsuda H, O Brien J, Silbert LC, Scheltens P, Soininen H, Teipel S, Waldemar G, Fellgiebel A, Barnes J, Firbank M, Gerritsen L, Henneman W, Malykhin N, Pruessner JC, Wang L, Watson C, Wolf H, deleon M, Pantel J, Ferrari C, Bosco P, Pasqualetti P, Duchesne S, Duvernoy H, Boccardi M for the EADC -European Alzheimer s Disease Consortium and the ADNI - Alzheimer s Disease Neuroimaging Initiative. The EADC-ADNI Harmonized Protocol for Hippocampal Segmentation on Magnetic Resonance: Evidence of Validity. (accepted for publication in Alzheimer's & Dementia on June 17, 2014). Cavedo E, Pievani M, Boccardi M, Galluzzi S, Bocchetta M, Bonetti M, Thompson PM, Frisoni GB. Medial temporal atrophy in early and late-onset Alzheimer's disease. Neurobiology of Aging Sep;35(9): Boccardi M, Bocchetta M, Apostolova LG, Barnes J, Bartzokis G, Corbetta G, DeCarli C, detoledo-morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duvernoy H, Duchesne S, Jack Jr CR, Frisoni GB, for the EADC-ADNI Working Group on the Harmonized Protocol for Manual Hippocampal Segmentation. Delphi Definition of the EADC-ADNI Harmonized Protocol for Hippocampal Segmentation on Magnetic Resonance. (accepted for publication in Alzheimer's & Dementia on February 17, 2014). Bocchetta M, Boccardi M, Ganzola R, Apostolova LG, Preboske G, Wolf D, Ferrari C, Pasqualetti P, Robitaille N, Duchesne S, Jack CR, Frisoni GB, for the EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Segmentation and the Alzheimer s Disease Neuroimaging Initiative. Harmonized benchmark labels of the hippocampus on MR: the EADC- ADNI project. (accepted for publication in Alzheimer's & Dementia on January 13, 2014). Boccardi M, Bocchetta M, Apostolova LG, Preboske G, Robitaille N, Pasqualetti P, Collins LD, Duchesne S, Jack CR, Frisoni GB. Establishing Magnetic Resonance Images Orientation for the EADC-ADNI Manual Hippocampal Segmentation Protocol. Journal of Neuroimaging Nov 26. doi: /jon Frisoni GB, Bocchetta M, Chételat G, Rabinovici GD, de Leon MJ, Kaye J, Reiman EM, Scheltens P, Barkhof F, Black SE, Brooks DJ, Carrillo MC, Fox NC, Herholz K, Nordberg A, Jack jr CR, Jagust WJ, Johnson KA, Rowe CC, Sperling RA, Thies W, Wahlund L-O, Weiner MW, Pasqualetti P, DeCarli C, for ISTAART s NeuroImaging Professional Interest Area. Imaging Markers for Alzheimer s Disease: Which versus How. Neurology Jul 30;81(5): Clerx L, van Rossum IA, Burns L, Knol DL, Scheltens P, Verhey F, Aalten P, Lapuerta P, van de Pol L, van Schijndel R, de Jong R, Barkhof F, Wolz R, Rueckert D, Bocchetta M, Tsolaki M, Nobili F, Wahlund LO, Minthon L, Frölich L, Hampel H, Soininen H, Visser PJ. Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment. Neurobiology of Aging Aug;34(8): Pievani M, Bocchetta M, Boccardi M, Cavedo E, Bonetti M, Thompson PM, Frisoni GB. Striatal morphology in early-onset and late-onset Alzheimer's disease: a preliminary study. Neurobiology of Aging. Volume 34, Issue 7, Pages , July Boccardi M, Bocchetta M, Ganzola R, Robitaille N, Redolfi A, Duchesne S, Jack CJ, Frisoni GB, for the EADC-ADNI Working Group on The Harmonized Protocol for Hippocampal Volumetry, and for the Alzheimer s Disease Neuroimaging Initiative. Operationalizing protocol differences for EADC-ADNI manual hippocampal segmentation. Alzheimer's & Dementia May 21. pii: S (13) doi: /j.jalz [Epub ahead of print]. Boccardi M, Bocchetta M, Aronen HJ, Repo-Tiihonen E, Vaurio O, Thompson PM, Tiihonen J, Frisoni GB. Atypical nucleus accumbens morphology in psychopathy: another limbic piece in the puzzle. International Journal of Law and Psychiatry, Volume 36, Issue 2, Pages , March Boccardi M, Ganzola R, Bocchetta M, Pievani M, Redolfi A, Bartzokis G, Camicioli R, Csernansky J, de Leon MJ, detoledo- Morrell L, Killiany RJ, Lehéricy S, Pantel J, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack CR Jr, Frisoni GB. Survey of Protocols for the Manual Segmentation of the Hippocampus: Preparatory Steps Towards a Joint EADC-ADNI Harmonized Protocol running title: Towards a harmonized hippocampal segmentation. Journal of Alzheimer s Disease. Volume 26, Issue 0, Pages 61-75, January (Also published in Handbooks of Alzheimer's Disease, Volume 25, Suppl. 3; July 2011). Chapter Book: Boccardi M, Ganzola R, Bocchetta M, Pievani M, Redolfi A, Bartzokis G, Camicioli R, Csernansky JG, de Leon MJ, detoledo- Morrell L, Killiany RJ, Lehéricy S, Pantel J, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack CR Jr, Frisoni GB. Survey of protocols for the manual segmentation of the hippocampus: preparatory steps towards a joint EADC-ADNI harmonized protocol. Handbook of Imaging the Alzheimer brain, Volume 2 Advances in Alzheimer s Disease. Editors: J.W. Ashford, A. Rosen, M. Adamson, P. Bayley, O. Sabri, A. Furst, S.E. Black and M. Weiner July 2011, 824 pp., ISBN (print), ISBN (online) / J Alzheimers Dis. 2011;26 Suppl 3: doi: /JAD Page 4/8 - Curriculum vitae of

5 Peer-Review Congress Abstracts*: *The full list of Published Congress Abstracts is reported in the Appendix Boccardi M, Bocchetta M, Ferrari C, Duchesne S, Jack C, Frisoni G. The EADC-ADNI Harmonized Protocol for Hippocampal Segmentation on Magnetic Resonance: Evidence of Validity. Neurology. Volume 82(10): Supplement S48.006, April 8, Apostolova L, Zarow C, Biado K, Babakchanian S, Boccardi M, Somme J, Honarpisheh H, Blanken A, Brook J, Tung S, Ng D, Alger J, Vinters H, Bocchetta M, Duvernoy H, Jack C, Frisoni G. Pathologic validation of the EADC-ADNI Harmonized Hippocampal Protocol. Neurology. Volume 82(10): Supplement P6.331, April 8, Boccardi M, Bocchetta M, Apostolova L, Ganzola R, Preboske G, Wolf D, Pasqualetti P, Robitaille N, Duchesne S, Jack C, Frisoni G. EADC-ADNI Benchmark Images for Harmonized Hippocampal Segmentation. Neurology, Volume 80(Meeting Abstracts 1): P06.028, February 12, Pievani M, Bocchetta M, Boccardi M, Galluzzi S, Bonetti M, Thompson P, Frisoni GB. Striatal Abnormalities in Early-Onset and Late-Onset Alzheimer's Disease. Neurology, Volume 78, Suppl. 1, April Boccardi M, Bocchetta M, Apostolova L, Barnes J, Bartzokis G, Corbetta G, DeCarli C, DeToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany R, Malykhin N, Pasqualetti P, Pruessner J, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duchesne S, Jack C, Frisoni G. Delphi Consensus on Landmarks for the Manual Segmentation of the Hippocampus on MRI: Preliminary Results from the EADC-ADNI Harmonized Protocol Working Group. Neurology, Volume 78, Suppl. 1, April Boccardi M, Bocchetta M, Ganzola R, Robitaille N, Redolfi A, Bartzokis G, Camicioli R, Csernansky JG, de Leon MJ, detoledo-morrell L, Killiany RJ, Lehéricy S, Pantel J, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack CR, Frisoni GB. Operationalization of Differences among Protocols for Manual Hippocampal Segmentation: Quantitative Data for EADC-ADNI Consensual Decisions on a Harmonized Protocol. Neurology, Volume 76, Issue 9, Pages A661-A661, Suppl. 4, March International Congress Attendance: Alzheimer's Imaging Consortium (AIC) - Alzheimer's Association International Conference (Copenaghen, July 12-17, 2014): "Italian network for autosomal dominant Alzheimer s Disease and Frontotemporal Lobar Degeneration (ItalianDIAfN)", poster presentation. 13 th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy (Geneva, March 26-29, 2014): "Italian Network For Autosomal Dominant Alzheimer s Disease and Frontotemporal Lobar Degeneration (ItalianDIAfN): definition of protocols for data collection and genetic counselling, "The Use of Biomarkers for the Etiologic Diagnosis of Mild Cognitive Impairment in Europe: a Survey of the European Alzheimer s Disease Consortium" and "The EADC-ADNI Harmonized Protocol for Hippocampal Segmentation on Magnetic Resonance: Evidence of Validity", poster presentation. 9 th Congress SINdem (Firenze, March 13-15, 2014): "Italian Network For Autosomal Dominant Alzheimer s Disease and Frontotemporal Lobar Degeneration (ItalianDIAfN): definition of protocols for data collection and genetic counselling poster presentation. 6 th Clinical Trials on Alzheimer s Disease (San Diego, November 14-16, 2013): Survey of segmentation protocols for manual hippocampal volumetry: preparatory phase for an EADC-ADNI harmonization effort, poster and oral presentation. 8 th Congress SINdem (Perugia, March 13-15, 2013): Definition of EADC-ADNI Harmonized Protocol for Hippocampal Segmentation, and Italian Network For Autosomal Dominant Alzheimer s Disease And Frontotemporal Lobar Degeneration, poster presentation. Biomarkers for Brain Disorders: Challenges and Opportunities 2013 (Cambridge, February 3-5, 2013): Definition Of Harmonized Protocol For Hippocampal Segmentation, oral presentation. 15 th International Psychogeriatric Association (Den Haag, September 6-9, 2011): Harmonization Of Protocols For The Manual Tracing Of The Hippocampus: An EADC-ADNI Joint Effort, oral presentation. 3 rd Clinical Trials on Alzheimer s Disease (Toulouse, November 3-5, 2010): Survey of segmentation protocols for manual hippocampal volumetry: preparatory phase for an EADC-ADNI harmonization effort, poster presentation. Bergamo, August 1 st 2014 Signature Page 5/8 - Curriculum vitae of

6 APPENDIX - List of Published Congress Abstracts Bocchetta M, Galluzzi S, Kehoe P, Frisoni GB, for the Disease Markers Special Interest Group of the European Alzheimer s Disease Consortium. The Use of Biomarkers for the Etiologic Diagnosis of Mild Cognitive Impairment in Europe: a Survey of the European Alzheimer s Disease Consortium. Journal of Neurology, Volume 261, Issue 1 Supplement, page 79, May 2014 and European Journal of Neurology, Volume 21, Issue s1, page 763, May Bocchetta M, Pievani M, Babiloni C, Bruni AC, Scarpini E, Sorbi S, Tagliavini F, Padovani A, Benussi L, Bernardi L, Binetti G, Borroni B, Di Fede G, Di Maria E, Fostinelli S, Galimberti D, Gennarelli M, Ghidoni R, Marzano N, Mega A, Nacmias B, Piaceri I, Porteri C, Rossi G, Suardi S, Vecchio F, Frisoni GB. Italian Network For Autosomal Dominant Alzheimer s Disease and Frontotemporal Lobar Degeneration (ItalianDIAfN): definition of protocols for data collection and genetic counselling. Journal of Alzheimer's Disease, Volume 41, Suppl. 2, S5-S6, Boccardi M, Bocchetta M, Barkhof F, Bauer C, Blair M, Burton, Cavedo E, Christensen A, Frederiksen KS, Grothe MJ, Lanfredi M, Lehéricy S, Liu Y, Martinez O, Nishikawa M, Portegies M, Preboske G, Stoub T, Swihart T, Tinley M, Ward C, Ferrari C, Pasqualetti P, Duchesne S, Jack CR, Frisoni GB, for the EADC-ADNI group for the Harmonization of the Harmonized Protocol. Validation of the EADC-ADNI Harmonized Protocol for Manual Hippocampal Segmentation: Preliminary Results. The Journal of Nutrition, Health & Aging, Volume 17, Number 9, 802, Boccardi M, Bocchetta M, Nishikawa M, Ganzola R, Grothe M, Wolf D, Duchesne S, Jack CR, Frisoni GB. Providing standardized labels of the EADC-ADNI Harmonized Hippocampal Protocol for automated algorithm training. The Journal of Nutrition, Health & Aging, Volume 17, Number 9, 826, Frisoni GB, Babiloni C, Bruni AC, Scarpini E, Sorbi S, Tagliavini F, Bocchetta M, Pievani M, Padovani A. Italian Network For Autosomal Dominant Alzheimer s Disease And Frontotemporal Lobar Degeneration. The Journal of Nutrition, Health & Aging, Volume 17, Number 9, 825, Boccardi M, Robitaille N, Valdivia F, Bocchetta M, Bauer C, Blair M, Burton E, Cavedo E, Christensen A, Frederiksen KS, Grothe M, Lanfredi M, Liu Y, Martinez O, Nishikawa M, Portegies M, Pronk M, Stoub T, Swihart T, Ward C, Apostolova L, Ganzola R, Preboske G, Wolf D, Jack C, Duchesne S, Frisoni G. Training for manual hippocampal segmentation based on the EADC-ADNI harmonized protocol. Alzheimer's & Dementia, Volume 9, Issue 4, Supplement, Pages P57-P58. July Boccardi M, Bocchetta M, Nishikawa M, Ganzola R, Grothe M, Wolf D, Duchesne S, Jack C, Frisoni G. Providing standardized labels of the EADC-ADNI Harmonized Hippocampal Protocol for automated algorithm training. Alzheimer's & Dementia, Volume 9, Issue 4, Supplement, Page P858, July Duchesne S, Valdivia F, Robitaille N, Valdivia A, Apostolova L, Bocchetta M, Ganzola R, Preboske G, Wolf D, Boccardi M, Jack C, Frisoni G. Manual segmentation certification platform for the EADC-ADNI harmonized protocol for the hippocampal volumetry project. Alzheimer's & Dementia, Volume 9, Issue 4, Supplement, Pages P409-P410, July Boccardi M, Robitaille N, Valdivia F, Bocchetta M, Bauer C, Blair M, Burton E, Cavedo E, Christensen A, Frederiksen KS, Grothe M, Lanfredi M, Liu Y, Martinez O, Nishikawa M, Portegies M, Pronk M, Stoub T, Swihart T, Ward C, Apostolova L, Ganzola R, Preboske G, Wolf D, Jack C, Duchesne S, Frisoni G. Training for manual hippocampal segmentation based on the EADC-ADNI harmonized protocol. Alzheimer's & Dementia, Volume 9, Issue 4, Supplement, Pages P404-P405, July Boccardi M, Bocchetta M, Barkhof F, Bauer C, Blair M, Boutet C, Burton E, Cavedo E, Christensen A, Frederiksen KS, Grothe M, Hollander S, Lanfredi M, Liu Y, Martinez O, Nishikawa M, Portegies M, Preboske G, Stoub T, Swihart T, Tinley M, Ward C, Ferrari C, Pasqualetti P, Duchesne S, Jack CR, Frisoni G. Validation of the EADC-ADNI Harmonized Protocol for Manual Hippocampal Segmentation: Preliminary Results. Alzheimer's & Dementia, Volume 9, Issue 4, Supplement, Page P868, July Lorenzi M, Bocchetta M, Ayache N, Pennec X, Frisoni G. Conversion to MCI in healthy individuals with abnormal CSF Aβ42 levels is associated with specific longitudinal morphological changes of the brain. Alzheimer's & Dementia, Volume 9, Issue 4, Supplement, Pages P47-P48. July Lorenzi M, Bocchetta M, Ayache N, Pennec X, Frisoni G. Conversion to MCI in healthy individuals with abnormal CSF Aβ42 levels is associated with specific longitudinal morphological changes of the brain. Alzheimer's & Dementia, Volume 9, Issue 4, Supplement, Page P596. July Duchesne S, Valdivia F, Robitaille N, Abiel Valdivia F, Bocchetta M, Boccardi M, Jack CR, Frisoni GB. Manual segmentation certification platform. Medical Measurements and Applications Proceedings (MeMeA), 2013 IEEE International Symposium on. IEEE. pp May, /MeMeA Boccardi M, Bocchetta M, Apostolova L, Ganzola R, Preboske G, Wolf D, Pasqualetti P, Robitaille N, Duchesne S, Jack C, Frisoni G. EADC- ADNI Benchmark Images for Harmonized Hippocampal Segmentation. Neurology, Volume 80(Meeting Abstracts 1): P06.028, February 12, Boccardi M, Bocchetta M, Apostolova L, Barnes J, Bartzokis G, Corbetta G, DeCarli C, detoledo-morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Page 6/8 - Curriculum vitae of

7 Duchesne S, Jack CR, Frisoni GB, for the EADC-ADNI Working Group on The Harmonized Protocol for Hippocampal Volumetry Definition of Harmonized Protocol for Hippocampal Segmentation. Neurodegenerative Diseases (Alzheimer s and Parkinson s Diseases: Advances, Concepts and New Challenges), Volume 11, Suppl 1, Page 964, March Cavedo E, Pievani M, Bocchetta M, Boccardi M, Bonetti M, Thompson PM, Frisoni GB. Effect of APOE Genotype on Striatal Atrophy in Early and Late Onset Alzheimer's Disease. Neurodegenerative Diseases (Alzheimer s and Parkinson s Diseases: Advances, Concepts and New Challenges), Volume 11, Suppl 1, Page 966, March Boccardi M, Bocchetta M, Apostolova L, Barnes J, Bartzokis G, Corbetta G, DeCarli C, detoledo-morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duchesne S, Jack CR, Frisoni GB. Definition of Harmonized Protocol for Hippocampal Segmentation. The Journal of Nutrition, Health & Aging, Volume 16, 800, Boccardi M, Bocchetta M, Apostolova L, Barnes J, Bartzokis G, Corbetta G, DeCarli C, detoledo-morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duchesne S, Jack CR, Frisoni GB. Definition of Harmonized Protocol for Hippocampal Segmentation. The Journal of Nutrition, Health & Aging, Volume 16, , Boccardi M, Bocchetta M, Apostolova L, Barnes J, Bartzokis G, Corbetta G, DeCarli C, DeToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany R, Malykhin N, Pasqualetti P, Pruessner J, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duchesne S, Jack CR, Frisoni GB; Definition of Harmonized Protocol for Hippocampal Segmentation. Alzheimer's & Dementia, Volume 8, Issue 4, Suppl 2, 23-24, July Boccardi M, Bocchetta M, Apostolova L, Barnes J, Bartzokis G, Corbetta G, DeCarli C, DeToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany R, Malykhin N, Pasqualetti P, Pruessner J, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duchesne S, Jack CR, Frisoni GB; Definition of Harmonized Protocol for Hippocampal Segmentation. Alzheimer's & Dementia, Volume 8, Issue 4, Suppl 2, 257, July Pievani M, Bocchetta M, Boccardi M, Galluzzi S, Bonetti M, Thompson P, Frisoni GB. Morphological Differences in the striatum in early- and late-onset Alzheimer s Disease. Alzheimer's & Dementia, Volume 8, Issue 4, Suppl 2, 25, July 2012 Pievani M, Bocchetta M, Boccardi M, Galluzzi S, Bonetti M, Thompson P, Frisoni GB. Morphological Differences in the striatum in early- and late-onset Alzheimer s Disease. Alzheimer's & Dementia, Volume 8, Issue 4, Suppl 2, 239, July 2012 Pievani M, Bocchetta M, Boccardi M, Galluzzi S, Bonetti M, Thompson P, Frisoni GB. Striatal Abnormalities in Early-Onset and Late-Onset Alzheimer's Disease. Neurology, Volume 78, Suppl. 1, April Boccardi M, Bocchetta M, Apostolova L, Barnes J, Bartzokis G, Corbetta G, DeCarli C, DeToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany R, Malykhin N, Pasqualetti P, Pruessner J, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duchesne S, Jack C, Frisoni G. Delphi Consensus on Landmarks for the Manual Segmentation of the Hippocampus on MRI: Preliminary Results from the EADC-ADNI Harmonized Protocol Working Group. Neurology, Volume 78, Suppl. 1, April RJ, Lehericy S, Pantel J, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack CR, Frisoni GB. Differences among Protocols for Manual Hippocampal Segmentation: Preparatory Steps to an EADC ADNI Delphi Panel for the Development of a Harmonized Protocol. The Journal of Nutrition, Health & Aging, Volume 15, Suppl 1, S18, RJ, Lehéricy S, Pantel J, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack CR, Frisoni GB; Estimating the Impact of Differences among Protocols for Manual Hippocampal Segmentation on Alzheimer s Disease-Related Atrophy: Preparatory Phase for a Harmonized Protocol. Alzheimer s & Dementia, Volume 7, Issue 4, Suppl 1, S , July RJ, Lehéricy S, Pantel J, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack CR, Frisoni GB; Estimating the Impact of Differences among Protocols for Manual Hippocampal Segmentation on Alzheimer s Disease-Related Atrophy: Preparatory Phase for a Harmonized Protocol. Alzheimer s & Dementia, IC-03-05, Volume 7, Issue 4, Suppl 1, S7-8, July RJ, Lehéricy S, Pantel J, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack CR, Frisoni GB. Operationalization of Differences among Protocols for Manual Hippocampal Segmentation: Quantitative Data for EADC-ADNI Consensual Decisions on a Harmonized Protocol. Neurology, Volume 76, Issue 9, Pages A661-A661, Suppl. 4, March RJ, Lehéricy S, Pantel S, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack Jr CR, Frisoni GB. Survey of Protocols for Manual Page 7/8 - Curriculum vitae of

8 Hippocampal Volumetry: Preparatory Steps for an EADC-ADNI Harmonized Protocol. Neurodegenerative Diseases (Alzheimer s and Parkinson s Diseases: Advances, Concepts and New Challenges), Volume 8, Suppl 1, Page 1, March Boccardi M, Ganzola R, Duchesne S, Robitaille N, Bocchetta M, Redolfi A, Bartzokis G, Camicioli R, Csernansky JG, de Leon MJ, detoledo- Morrell L, Killiany RJ, Lehéricy S, Pantel J, Pruessner JC, Soininen H, Watson C, Jack C, Frisoni GB. Survey of segmentation protocols for manual hippocampal volumetry: preparatory phase for an EADC-ADNI harmonization effort. The Journal of Nutrition, Health & Aging, Volume 14, Suppl 2, S12, Boccardi M, Bocchetta M, Thompson P, Tiihonen J, Frisoni G. Hypotrophic nucleus accumbens in psychopathy: another limbic tile in the puzzle. Neurological Sciences, Volume 31, Suppl, S304, Page 8/8 - Curriculum vitae of

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