Trail Making Test part A part B. Mild Cognitive Impairment MCI MCI. Kennedy 1981 Bornstein Rey Osterrieth 3. Berry 1991.

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1 Trail Making Testpart Apart B 300 Mini Mental State ExaminationN Rey Osterrieth Key Words healthy elderly personsneuropsychological measuresageyears of education Mild Cognitive ImpairmentMCI MCI 2004 Mitrushina 1999 Mini Mental State Examination MMSE Crum 1993 Trail Making Test part A part B TMT A B Kennedy 1981Bornstein 1985 Rey Osterrieth ROCF Boone Berry

2 TMT A B ROCF Tukey Kramer PGC Lawton MMSE TMT A B Halstead Reitan neuropsychological test battery N

3 1818 ROCF Taylor Lezak TMT A B Kendall 4 Kruskal Wallis Steel Dwass 2 Mann Whitney MMSE p p p 0.01TMT A B A p 0.001B p 0.01 A B p p 0.05 p 0.01 ROCF ROCF p p

4 Kruskal Wallis Steel Dwass p 0.01 p 0.05TMT Ap 0.05ROCF p p p p 0.01 p 0.05TMTA p 0.01B p p 0.01 TMT B p 0.05TMT A p p 0.05TMT A p

5 TMT A TMT B 4

6 MMSE ROCF ROCF TMT A B 9 TMT A 4 2 Kennedy 1981 Kennedy 1981 Bornstein 1985Ivnik TMT A Bornstein TMT A B Kennedy 1981 Bornstein 1985Ernst Ivnik 1996 TMT A TMT A B 2 2 TMT A TMT B

7 MMSEROCF MMSE Crum 1993 Grigoletto 1999Dufouil MMSE Dufouil ROCF IQ 3 Mitrushina Boone Chiulli Ardila Trail Making Test 56 : 567

8 , Ardila, A., Rosselli, M. & Rosas, P. : Neuropsychological assessment in illiterates ; Visuospatial and memory abilities. Brain Cogn., 11 : , Berry, D. T. R., Allen, R. S. & Schmitt, F. A. : Rey Osterrieth Complex Figure ; Psychometric characteristics in a geriatric sample. Clin. Neuropsychol., 5 : , Boone, K. B., Lesser, I. M., Hill Gutierrez, E., et al. : Rey Osterrieth Complex Figure performance in healthy, older adults ; Relationship to age, education, sex, and IQ. Clin. Neuropsychol., 7 : 22 28, Bornstein, R. A. : Normative data on selected neuropsychological measures from a nonclinical sample. J. Clin. Psychol., 41 : , Bornstein, R. A. & Suga, L. J. : Educational level and neuropsychological performance in healthy elderly subjects. Dev. Neuropsychol., 4 : 17 22, Chiulli, S. J., Haaland, K. Y., LaRue, A., et al. : Impact of age on Drawing the Rey Osterrieth Figure. Clin. Neuropsychol., 9 : , Crum, R. M., Anthony, J. C., Bassett, S. S., et al. : Population based norms for the Mini Mental State Examination by age and education level. JAMA, 269 : , Dufouil, C., Clayton, D., Brayne, C., et al. : Population norms for the MMSE in the very old. Neurology, 55 : , Ernst, J. Neuropsychological problem solving skills in the elderly. Psychol. Aging, , Grigoletto, F., Zappala, G., Anderson, D. W., et al. : Norms for the Mini Mental State Examination in a healthy population. Neurology, 53 : , : , : , Ivnik, R. J., Malec, J. F., Smith, G. E., et al. Neuropsychological tests norms above age 55 ; COWAT, BNT, MAE token, WRAT R reading, AMNART, STROOP, TMT, and JLO. Clin. Neuropsychol., 10 : , : 26 30, Kennedy, K. J. : Age effects on Trail Making Test performance. Percept. Mot. Skills, 52 : , : , Lawton, M. P. : The Philadelphia Geriatric Center Morale Scale ; A revision. J. Gerontol., 30 : 85 89, Lezak, M. D. : Neuropsychological Assessment.4th Ed., Oxford University Press, New York, 2004, pp Mitrushina, M. N., Boone, K. B. & D Elia, L. F. : Handbook of Normative Data for Neuropsychological Assessment. Oxford University Press, New York, Mitrushina, M. N., Satz, P. & Chervinsky, A.B. : Efficiency of recall on the Rey Osterrieth Complex Figure in normal aging. Brain Dysfunct., 3 : ,

9 Abstract Effects of age and years of education on neuropsychological data of Japanese healthy elderly persons Hiromi Harada Masako Notoya Masao Nakanishi Nakako Fujiwara Katsumi Inoue In order to provide neuropsychological data on Japanese healthy elderly persons, we explored the neuropsychological performance of 92 subjects aged years old. We examined the effects of age and years of education on their performance, and showed data stratified by age and educational level. We investigated the performance scores of the subjects according to age and/or educational level. Scores on the Kana pick up testnonsense words and story and Trail Making Testpart A, part Bwere found to be significantly associated with age and years of education. 300 word naming test scores were also significantly associated with age. Scores on the Mini Mental State Examination, the story recall test in the Nishimura Dementia Scaleimmediate and delayed recall, and the Rey Osterrieth Complex Figure Testcopy and immediate recallwere not affected by age or years of education. These findings indicate that it is necessary to take the effects of age and years of education into consideration when interpreting scores on neuropsychological tests.

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