Research with Indigenous populations
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1 Research with Indigenous populations Maude St-Onge, MD, PhD, FRCPC Medical Director of the Centre antipoison du Québec, CIUSSSCN Assistant Professor, Department of Family Medicine and Emergency medicine Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval Critical Care Physician and Emergency Physician Clinician-Scientist (Junior 1 FRQS) for the Population Health and Optimal Health Practice Research Unit, Trauma - Emergency - Critical Care Medicine, CHU de Quebec Research Centre
2 DISCLOSURE I have NO actual or potential conflict of interest in relation to this program. I WILL NOT discuss or describe the investigational or unlabelled ("offlabel") use of a medical device, product, or pharmaceutical that is classified by Health Canada as investigational for the intended use.
3 OBJECTIVES Describe the current literature concerning acute care provided to Indigenous patients. Detail the current knowledge concerning acute care provided to Indigenous poisoned patients. Describe the current care provided to Indigenous poisoned patients in the province of Quebec.
4 INDIGENOUS POPULATIONS 4.9% of Canadian population In the province of Quebec: 10 Indigenous nations in 55 communities Inuits in 14 villages Crees and Inuits territories Covered by the Quebec healthcare system With some home services covered by Health Canada First Nations territories Covered by Health Canada, governed by Band Councils Access to the Quebec healthcare system for specialized care Statistique Canada,
5 INDIGENOUS POPULATIONS 35% of First Nations consider their access to healthcare services is inferior to the rest of the country. 15% considered they had injust or inappropriate treatment because they are Indigenous. Racisms experiences were reported by 39-78% of participants depending on the study. Premières Nations, 2003 Organisation nationale de la santé autochtone, 2003 College of Family Physicians of Canada and Indigenous Physicians Association of Canada., 2016
6 POISONINGS 4.9% of canadian population, 2.3% in Québec In Quebec: 10 Indigenous nations in 55 communities Inuit in 14 villages More chronic diseases, more alcohol consomption or smoking
7 POISONINGS 4.9% of canadian population, 2.3% in Québec In Quebec: 10 Indigenous nations in 55 communities Inuit in 14 villages More chronic diseases, more alcohol consomption or smoking
8 POISONINGS IN INDIGENOUS POPULATIONS Centre antipoison du Québec (2015): Nunavik: 1,160 poisonings per 100,000 persons per year James Bay: 1,021 poisonings per 100,000 persons per year Northern Quebec: 918 poisonings per 100,000 persons per year Montreal and Laval regions: 437 and 416 poisoning cases per 100,000 persons per year Poison and Drug Information Service in Alberta (2016): Greatest number of calls from Yellowknife, Fort Smith and Inuvik Statistique Canada,
9 KNOWLEDGE Scoping review CARIPP ( CARE for Indigenous Poisoned Patients ) PRACTICE Retrospective study Goal = Improve access and quality to evidenced-informed culturally competent acute care for Indigenous poisoned patients PERCEPTIONS Qualitative studies: patients / relatives Maude St-Onge Ella Diendere Richard Bélanger Gabrielle Castilloux Nancy Gros-Louis McHugh François Lauzier Mélanie Lemire Marie-Claude Lyonnais Marie-Claude René Jille Elaine Torrie Alexis Turgeon Pierre Ayotte
10 CURRENT LITERATURE Scoping review of the literature concerning North Americain Indigenous or Metis patients Objectives: Identify and describe within the literature what exists regarding acutely ill North American Indigenous or Metis patients Describe which proportion of the literature concerns acutely poisoned Indigenous patients Vigneault, Abi Hanna, Diendere, St-Onge, 2018
11 CURRENT LITERATURE Vigneault, Abi Hanna, Diendere, St-Onge, 2018
12 CURRENT LITERATURE / KNOWLEDGE Most articles concerned lung diseases (n=61), healthcare use (n=37), injuries (n=28), heart diseases (n=18) or neurological diseases (n=18) Only 6 articles concerning poisonings: Acetaminophene: 3 Sedatives-hypnotics: 1 Botulism: 1 Hydocarbone poisoning in two children: 1 Vigneault, Abi Hanna, Diendere, St-Onge, 2018
13 CURRENT KNOWLEDGE We know a little concerning chronic exposure to xenobiotics in Indigenous population. We no very little concerning Indigenous patients acutely poisoned except for epidemiologic data.
14 CURRENT CARE Retrospective study based on poison centre data Objectives: Describe the delays in the continuum of healthcare and clinical outcomes of Indigenous and non indigenous poisoned patients in rural regions Compare delays and clinical outcomes in both populations Calls for Indigenous or non-indigenous poisoned patients in rural regions (June 2016 June 2018) Diendere, St-Onge, Turgeon 2018
15 CURRENT CARE Indigenous poisoned patients in one of the 11 communities more than 50 km from urban regions and non-indigenous poisoned patients in rural or small town (150 per group) Patients excluded: with multiple exposures with concomitant trauma Diendere, St-Onge, Turgeon 2018
16 Eligible patients, N = 954 Individuals excluded n = 612 Cases observed at home (8) Not been referred or seen in an hospital (52) Not poisoning cases (22) Missing data concerning provided treatment (40) Minor clinical effect or nontoxic case, without follow-up phone call (351) Chronic poisoning (19) Impossible follow-up phone call (118) Excluded to be able to perform matching with same number in both groups (2) Final sample, n = 342 Indigenous patients (n = 171) Non-Indigenous patients (n = 171) Diendere, St-Onge, Turgeon 2018
17 Diendere, St-Onge, Turgeon 2018
18 Diendere, St-Onge, Turgeon 2018
19 Diendere, St-Onge, Turgeon 2018
20 Diendere, St-Onge, Turgeon 2018
21 CURRENT CARE The time to obtain all the management recommended by the poison center was higher in the Indigenous group compared to the Non- Indigenous group (11.7 hours vs. 9.2 hours, adults: OR 3.8 [1.0; 15.0], p = 0.05). No significant diffirences in outcomes. Many limitations. Diendere, St-Onge, Turgeon 2018
22 CURRENT CARE More questions than answers What happens to First Nations? Why Indigenous do not call the poison centre themselves? Which interventions recommended by the poison centre are delayed? Is our care culturally-sensitive? Diendere, St-Onge, Turgeon 2018
23 PERCEPTIONS Qualitative study using the Grounded Theory Approach: What are the determinants of access to culturally competent acute care for Indigenous poisoned patients (voluntary poisonings)? Objectives: To explore the determinants of access to culturally competent acute care by an in-depth understanding of: Indigenous poisoned patients experiences in the current healthcare continuum Relatives experiences of Indigenous poisoned patients in the current healthcare continuum St-Onge et al. 2018
24 CHALLENGES Still looking for funding. Patients and community involvement is key, but remains a challenge: How to reach them? To communicate with them? Who to reach? When to reach them? How long after a suicide attempt? How to collaborate to build studies with them? St-Onge et al. 2018
25 KNOWLEDGE Scoping review CARIPP ( CARE for Indigenous Poisoned Patients ) PRACTICE Retrospective study PERCEPTIONS Qualitative studies: patients / relatives Questions? Goal = Improve access and quality to evidenced-informed culturally competent acute care for Indigenous poisoned patients
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