Grants & Donations 2016 (Patient Associations, Scientific Societies and Charitable Contributions) ITALY

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1 Z Grants & Donations 2016 (s, Scientific Societies and Charitable s) ITALY Name of Beneficiary Institution Organization Program/Project Description Support A.D.I.PSO. Associazione per la Difesa degli Psoriasici A.M.R.E.R. Onlus (Associazione Malati Reumatici Emilia Romagna) A.R.R. Associazione Riconosciuta per la ricerca in Reumatologia AI.Ma.Me. (Associazione Italiana Malati di Melanoma) AIPI Onlus (Associazione Ipertensione Polmonare Italiana Onlus) AMICI Onlus AMIP Onlus - Associazione Malati di Ipertensione Polmonare Onlus Andrea Tudisco Onlus APMAR Onlus (Associazione Persone con Malattie Reumatiche) Associazione "Andrea Tudisco" Onlus Associazione "Salute con Stile" Associazione Culturale Giuseppe Dossetti Associazione NADIR Onlus Associazione Piccoli Grandi Cuori Associazione Sulla Strada Onlus AVIRALIA Onlus (Fondazione Italiana per gli Studi e le Ricerche Antivirali Onlus) University) A contribution given in partial support of the Press Campaign for the Psoriasis World Day to be held on October Financial Support Donation Italy EUR 15,000 3Q A contribution given in partial support of the project "Improvement and consolidation of the diagnostic/therapeutic path through the joint management of Gastroenterologist and Rheumatologist in patients with MICI and SpA". Financial Support Donation Italy EUR 14,000 4Q A contribution given to the Association in support of their institutional research. The contribution will be used for the Project Rationalization and Management of the Early Arthritis Clinic (EAC). Financial Support Donation Italy EUR 19,000 3Q A contribution given in partial support of the project "Support for people suffering from Melanoma". Financial Support Donation Italy EUR 10,000 4Q A contribution given in partial support of the Association's summer-autumn issue (July-September and October-December 2016) of their quarterly magazine AIPI news. Financial Support Donation Italy EUR 5,000 2Q A contribution in partial support of the projects of the Association AMICI Onlus, in particular for the study "The economic burden of IBD in Italy" whose objective is to estimate the direct and indirect costs of IBD in the Italian context. Financial Support Donation Italy EUR 10,000 2Q A contribution given in partial support of the Association's activities foreseen for In particular, a contribution to allow the Association to edit and send the December edition of their magazine and calendar for 2017 to their members. Financial Support Donation Italy EUR 5,000 2Q A contribution given in support of the project " Adopt a family from Andrew's House". Financial Support Donation Italy EUR 7,500 1Q A contribution given in partial support of the project "Theater therapy workshops". Financial Support Donation Italy EUR 5,000 4Q A contribution given to support the project "Adopt a family from the house of Andrea." Financial Support Donation Italy EUR 7,500 4Q A contribution given in support of the project "Mediterranean Diet as a tool for the reduction of the glycaemic variability in type 1 diabetes". Financial Support Donation Italy EUR 15,000 2Q A contribution given in support of the Association who through the organization of specific events such as conferences, debates, seminars, round tables and workshops give life to a cultural and programmatic comparison in which patient associations, researchers, scientific societies, exponents of the industry take part with the aim of bridging the gaps between the public and the institutions. Financial Support Donation Italy EUR 5,000 3Q A contribution given in support of the project "Doctor-Patient Communication: 10 Rules of behaviour". Financial Support Donation Italy EUR 10,000 3Q A contribution given in support of the project "Adopt a room" which provides help in the management of expenses for the "Polo dei Cuori" which is the association's house that provides hospitality for the young patients with congenital heart disease and their families during hospitalization at the S. Orsola-Malpighi in Bologna. Financial Support Donation Italy EUR 7,500 1Q A contribution given in partial support of the project "School for everyone" with the aim of ensuring access to education and power supply for children living in the most remote villages of Guatemala. The donation will be used in partial support of the acquisition of a means of transport that will take the children from their villages to the school. Financial Support Donation Italy EUR 7,500 1Q A contribution given in partial support of the AVIRALIA Foundation for their "Coupon Aids" campaign which began in the Likuni Mission in Milawi. The Foundation is engaged in the humanitarian program "SAVE THE FAMILIES FOR AFRICA" which aims to eliminate the vertical transmission of HIV "mother-child' in one of the African countries most affected by the scourge of AIDS: The Milawi. Within the scope of the project, the Foundation has developed a particular initiative called "Coupon Aids" facing women in 'sieropositive' pregnancies. Financial Support Donation Italy EUR 20,000 3Q

2 Name of Beneficiary Institution Organization Program/Project Description Support Comitato Accademia dei Pazienti Onlus Emergenza Sorrisi - Doctors for Smiling Children ONG FAI in Senegal Onlus Fondazione A.R.E.A. Fondazione Italiana Cuore e Circolazione Onlus GIRCCS Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale HEMOVE - Health and Motion Venice Association IncontraDonna Onlus Insieme contro il Cancro LORHEN Lombardy Rheumatology Network Medici in Africa Onlus Piccoli Grandi Cuori Progetto Emo-casa Rimettere le Ali Onlus Salute Donna Onlus A contribution given in partial support for the organization of their first workshop "The active and no longer passive participation of Patients in the process of Drug Research and Development" to be held in a two-day session (19-20 April 2016). Financial Support Donation Italy EUR 15,000 2Q A contribution given in support of the sporting event "Pietro Mennea: a champion of Solidarity" to be held 8-9 October Through this event the Association wants to raise awareness of public opinion and of young people to the values of sport and to support the Association's humanitarian interventions in favour of children with malformations to the face in poor countries by providing a humanitarian medical mission in Senegal in the coming months in memory of Pietro Mennea. Financial Support Donation Italy EUR 5,000 3Q A contribution given in support of the many activities and projects of the Association FAI in Senegal which includes allowing the most needy children to have access to education and healthcare, to help the infirmary to efficiently fight infant death, to increase the agricultural activity in the "Cooperative for Mothers" which allows the women to develop their productive activities. Financial Support Donation Italy EUR 15,000 4Q A contribution given in support of the organization of a training course dedicated to nursing staff engaged in the management of patients with diabetes mellitus. Financial Support Donation Italy EUR 7,000 1Q A contribution given to the Foundation for the project "Hearts on a Journey Cardiorace Sanit 2016". The first event will take place in Milan on September 29th on the occasion of the World Heart Day and subsequently repeated in Turin, Bologna, Florence, Bari and Rome. Financial Support Donation Italy EUR 12,000 3Q A contribution given in support of research and training activities of the GIRCCS, in particular for "The research and development project of genetic monitoring and mapping of the different phenotypes within the scope of rheumatic diseases: genetic database and therapeutic applications." Financial Support Donation Italy EUR 20,000 2Q A contribution given to HEMOV (an association for research on musculoskeletal diseases and related disabilities) in partial support of Project Colonna which is the first project of large impact that the Association HEMOVE intends to promote on illnesses of the vertebral column focusing in particular on low back pain and cervical pain. The Project was started in 2015 in a high school in Venice and is now being extended to other high schools in Verona, Padua and Matera. Financial Support Donation Italy EUR 10,000 3Q A contribution given in partial support of the Association's project "IncontraDonna Onlus theatrical laboratory" which provides theater therapy for the oncological patients and their families during 2016/2017. Financial Support Donation Italy EUR 20,000 2Q Other (Foundation that provides information and support for oncological patients through the A contribution given in support of a provision aimed at supporting an organization's institutional activity of primary prevention with particular reference to an activity of activities) education and awareness on the correct lifestyles of adolescents. Financial Support Donation Italy EUR 10,000 2Q A contribution in support of the association's institutional activities. In particular for the Project entitled "Improvement of the register Lorhen (Lombardy Rheumatology Network) and its management". Financial Support Donation Italy EUR 20,000 1Q A contribution given in partial support of the project "Ninna Nanna Africana" a training project for the staff dedicated to anesthesia and intensive care in the La Croix di Zinvié in Benin hospital. Financial Support Donation Italy EUR 6,250 4Q A contribution given in support of the project "Psychological assistance for children, Grown Up Congenital Heart (GUCH) patients and adults with congenital heart problems and their families". Financial Support Donation Italy EUR 5,000 3Q A contribution given in partial support of "Progetto Emo-casa" - Association for leukemia and other hematologic malignancies for clinical research and treatment at home. Financial Support Donation Italy EUR 3,000 3Q A contribution given in support of a Charity Dinner, organized by the Association "Rimettere le ali Onlus" in collaboration with "Borgo Ragazzi Don Bosco". The contribution will be used in support of activities run by this association, in particular for educational projects for young people in difficulty. Financial Support Donation Italy EUR 3,500 2Q A contribution given in partial support of the training activities provided to the volunteers of the Association. In 2016 five courses lasting two days each will be held in the Association's various regional branches. Financial Support Donation Italy EUR 10,000 3Q

3 Name of Beneficiary Institution Organization Program/Project Description Support Soccorso Clown S.C.S. Onlus Z Other (professional group operating in hospital wards) Grants & Donations OTHER INSTITUTIONS ITALY A contribution given in support of the project "Soccorso Clown" (project "Rescue Clowns" implemented at the "Bambino Gesù" hospital in Rome from September to December) through our participation in the "2016 Stelvio Challenge" event. Financial Support Donation Italy EUR 10,000 2Q EUR 334,750 Name of Beneficiary Institution Institution Program/Project Description Support Azienda Ospedaliera dei Colli, Monaldi-Cotugno in Azienda Ospedaliera Papa Giovanni XXIII in Bergamo Azienda Ospedaliera Papa Giovanni XXIII in Bergamo Azienda Ospedaliera Regionale S. Carlo ini Potenza Azienda Ospedaliera Universitaria "Federico II" in Azienda Ospedaliera Universitaria "Sant'Anna" in Ferrara Azienda Ospedaliera Universitaria in Azienda Ospedaliera Universitaria Meyerin Florence Azienda Ospedaliera Universitaria San Martino in Genoa in support of the implementation of an educational project in patients at high cardiovascular risk after being affected by Acute Coronary Syndrome Financial Support Donation Italy EUR 15,000 4Q given at supporting a project for the Fibroscan and splenic optimization post - liver transplantation Financial Support Donation Italy EUR 20,000 1Q given in support of a project entitled "Maintenance and optimization of computerized drug prescription procedure" Financial Support Donation Italy EUR 12,500 4Q to optimizing the clinical diagnostic process of framing the infertile patient in order to rule out or confirm the presence of a uterine factor among the causes of infertility Financial Support Donation Italy EUR 15,000 1Q Donation given to support the creation of a regional network for the study and management of endometriosis in patients with chronic pelvic pain and infertility Financial Support Donation Italy EUR 20,000 4Q aimed at the implementation of a project entitled "Analysis of the therapeutic adherence rate in ambulatory patients with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis" Financial Support Donation Italy EUR 10,000 2Q aimed at supporting the activities of the surgery for early detection of arthritis Financial Support Donation Italy EUR 15,000 4Q s aimed at supporting a project on the evaluation of the metabolic risk in adolescents through a public awareness campaign on Diabetes Financial Support Donation Italy EUR 15,000 1Q in support of a project entitled "Organizational Project to reduce dropouts and improve time to pregnancy in a MAP public center" aimed at rationalizing the use of resources in health Financial Support Donation Italy EUR 15,000 1Q Azienda Ospedaliera/Arcispedale S. Maria Nuova in Reggio Emilia Azienda Ospedaliero Universitaria in Modena Azienda Ospedaliero Universitaria Policlinico "Vittorio Emanuele" in Catania Azienda Sanitaria Unica Regionale, Area Vasta n. 3 in Civitanova Marche Fondazione CNR Regione Toscana "G. Monasterio " per la Ricerca Medica e di Sanità Pubblica in Pisa Fondazione Policlinico Universitario A. Gemelli - Università Cattolica del Sacro Cuore in Rome Fondazione Salvatore Maugeri, Riabilitazione cardiologica in Milan Fondazione Scientifica Mauriziana Onlus in Turin given to implement a project to improve the quality of life in patients with IBD through early diagnosis of rheumatological complications Financial Support Donation Italy EUR 20,000 1Q Monetary donation for the acquisition of one multidisciplinary portable ultrasound unit for carrying out a project to improve the management of patients in the hospital with sepsis Financial Support Donation Italy EUR 14,884 4Q given to support the implementation of a project entitled "Managing a rheumatology clinic dedicated to patients with poly arthritis in order to improve welfare benefits" Financial Support Donation Italy EUR 15,000 1Q given to support a multifactorial, multidisciplinary, active and dynamic cardiovascular rehabilitation project Financial Support Donation Italy EUR 12,000 3Q given to suppot a project titled "Characterization of cardiometabolic risk in the different hormonal phases in a woman's life: basis for prevention of gender" Financial Support Donation Italy EUR 15,000 1Q given to support the project "Towards a hospital without infections" an awareness campaign for hand hygiene aimed at developing a program of initiatives to combat hospital infections Financial Support Donation Italy EUR 15,000 2Q Monetary donation for the purchase of one portable echocardiography to enable the diagnostics directly at the bedside, allowing to quickly detect and timely fatal injuries for the patient Financial Support Donation Italy EUR 22,000 3Q Donation given in support of an annual multi-sponsor project that identifies the activity of counseling as way of managing prescriptive appropriateness Financial Support Donation Italy EUR 15,000 1Q

4 Name of Beneficiary Institution Institution Program/Project Description Support H&S Qualità nel Software in favour of Local Health Unit in Rieti (Lazio region) A. Murri in Fermo Istituto Auxologico Italiano in Milan Istituto Giannina Gaslini in Genoa Istituto Giuseppe Toniolo di Studi Superiori (Policlinico Agostino Gemelli) in Milan Istituto Nazionale Tumori - Fondazione Pascale in Local Health Unit Torino 2 - Ospedale Amedeo di Savoia in Birago di Vische, Turin Ospedale "A. Pugliese-Ciaccio" in Catanzaro Ospedale "San Luca" Vallo della Lucania (Salerno) Ospedale Pediatrico Bambino Gesù in Rome Ospedale Università Campus Bio-Medico in Rome Rete Ematologica Pugliese presso Azienda Ospedaliera-Universitaria Policlinico in Bari Other (company that develops software and software-related products together with given in support of the populations affected by the earthquake consumables for medical in Amatrice (province of Rieti) for the purchase of consumable materials devices) s aimed at supporting a project entitled "Optimization of multidisciplinary management of patients with inflammatory bowel used for clinical examinations done by medical measuring instruments Indirect Support Donation Italy EUR 12,200 4Q diseases" Financial Support Donation Italy EUR 10,000 4Q aimed at supporting the project titled "The Rheumatology speaks to women" Financial Support Donation Italy EUR 15,000 1Q aimed at supporting the project "Team vascular access" with aim of increasing patient safety and improving business efficiency Financial Support Donation Italy EUR 10,000 3Q given to improve and strengthen the activity of care and doctor-patient communication regarding patients involved in specific desensitizing treatment or risky diagnostic tests Financial Support Donation Italy EUR 15,000 1Q s aimed at financing an annual cooperation contract for one registered nurse to be employed for monitoring vital signs of patients receiving chemotherapy that perform sporting activities Financial Support Donation Italy EUR 20,000 3Q given for a project entitled "Strengthening the contribution of the pharmaceutical industry in the context of antimicrobial stewardship" interventions" that involves a pharmacist to coordinate project activities Financial Support Donation Italy EUR 18,000 4Q given to support the widening of outpatient aimed at providing better patient care with the aim of improving knowledge and skills in the treatment of acute coronary syndromes Financial Support Donation Italy EUR 15,000 4Q aimed at improving the diagnostic and therapeutic process of couples who approach the MAP techniques Financial Support Donation Italy EUR 15,000 4Q aimed at improving the assistance and care of patients with respiratory allergy Financial Support Donation Italy EUR 12,000 4Q aimed at supporting the project titled "Optimizing the care pathway dedicated to patients with ulcerative colitis" Financial Support Donation Italy EUR 15,000 1Q given in support of the Hematology Pugliese Network for the implementation of the computer system of the Puglia Hematology, including the architecture of the computer network system Financial Support Donation Italy EUR 20,000 1Q Seconda Università degli Studi in Seconda Università degli Studi in Società Italiana di Farmacologia in Milan Università "Sapienza" in Rome Università Cattolica del Sacro Cuore - Complesso Integrato Columbus in Rome Università Cattolica del Sacro Cuore - IBD Unit in Rome Università degli Studi "Tor Vergata" in Rome Università degli Studi dell'insubria in Varese Università degli Studi in Ancona Università degli Studi in Brescia given in support of an annual project entitled "Early Detection of Chronic Bowel Disease and the role of the general practitioner" Financial Support Donation Italy EUR 15,000 4Q s aimed at supporting a project to optimize the identification and clinical management nephropathic patient Financial Support Donation Italy EUR 10,000 4Q given to support the implementation of new management and improvement of the website Financial Support Donation Italy EUR 15,000 1Q Monetary donation for the purchase of a Holter ECG device and related software for the diagnosis and treatment of cardiovascular diseases Financial Support Donation Italy EUR 4,636 4Q to optimizing the interdisciplinary management of patients with spondyloarthritis and IBD through the development of an integrated care pathway (rheuma-gastroenterology) Financial Support Donation Italy EUR 20,000 1Q s given to support a project for the implementation of the multidiscipllinary management of IBD patients Financial Support Donation Italy EUR 15,000 4Q in support of the creation of an electronic database for the management of ambulatory patients of the Division of Hematology with aim of optimizing the management of the web platform Redcap (Research Electronic Data Capture) to be used for the acquisition of data for purposes of clinical care Financial Support Donation Italy EUR 15,000 4Q given to support a project entitled "Antimicrobial stewardship program in immunosuppressed patients after solid organ transplantation" with aim of improving the multidisciplinary management and patient outcomes Financial Support Donation Italy EUR 20,000 4Q given to support the project entitled "Strengthening the surgery of inflammatory bowel disease and creation of an IBD-Unit" for the optimization of the management of patients with IBD Financial Support Donation Italy EUR 10,000 2Q aimed to support the project "HIV infection in migrant" to promote early diagnosis and access to treatment of the migrant population affected by HIV with special attention to the identification of possible risk factors Financial Support Donation Italy EUR 15,000 1Q

5 Name of Beneficiary Institution Institution Program/Project Description Support Università degli Studi in Florence Università degli Studi in Foggia Università degli Studi in Palermo Università degli Studi in Perugia Università degli Studi in Perugia Università degli Studi in Verona Università degli Studi Magna Graecia in Catanzaro Università La Sapienza in Rome University Trust - "Le Scotte" in Siena given to support a project on an educational program for patients with diabetes Financial Support Donation Italy EUR 10,000 4Q aimed at supporting the project "Application of new classification criteria ASAS (Assessments in Ankylosing Spondylitis) for the detection of signs and symptoms of no radiographic Spondyloarthropathies (nr-axspa) in patients attending the Early SpA" Financial Support Donation Italy EUR 15,000 1Q given in support of a development project to implement an algorithm for the identification of patients with autosomal dominant hypercholesterolemia Financial Support Donation Italy EUR 15,000 4Q given for the development of patient support activity that verifies the ability of the patient to measure by himself the effectiveness of anti-hypertensive; project also aims at identifying hypertensive patients at high cardiovascular risk Financial Support Donation Italy EUR 5,000 2Q given to support a project entitled "Implementation of an outpatient for the assessment of cardiovascular risk and quality of life of those affected by rheumatic and chronic-inflammatory systemic autoimmune diseases" Financial Support Donation Italy EUR 15,000 1Q in support of the implementation of an Enhanced Recovery After Surgery Program (ERAS) for patients undergoing colorectal resection minimally invasive Financial Support Donation Italy EUR 15,000 1Q given in support of diagnostic and therapeutic activity of the adult patient with IBD aimed at promoting a process of proper diagnosis, treatment and follow-up of patients with chronic intestinal diseases Financial Support Donation Italy EUR 10,000 1Q given for the implementation of a project titled " Patient Report Outcomes (PROs) Optimizing Program into clinical practice in rheumatology" Financial Support Donation Italy EUR 10,000 1Q s aimed at supporting a project to improve the levels and care pathways for patients with rheumatic diseases Financial Support Donation Italy EUR 15,000 4Q EUR 693,220

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