Congratulations to Van Wyk Awardee Ron Rosenfeld! A great scholar A remarkable scientist A most influential thinker A wonderful mentor and friend

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1 Congratulations to Van Wyk Awardee Ron Rosenfeld! A great scholar A remarkable scientist A most influential thinker A wonderful mentor and friend

2 What does it take to win a Van Wyk Award? 1. Impeccable training 1968 B.A. Columbia University summa cum laude 1973 M.D. Stanford (with honors) Intern-resident-fellow at Stanford Private Practice, Santa Barbara

3 What does it take to win a Van Wyk Award? 2. Impactful Academic Positions Assistant to Full Professor, Stanford Chairman of Pediatrics - OHSU Senior VP - Lucile Packard Foundation

4 What does it take to win a Van Wyk Award? 3. Publication record Miller WB and Rosenfeld RG: A psychophysiological study of denial following acute myocardial infarction. J Psychosom Res 19:43 54, 1975 Followed by more than 600 papers in which he characterized IGFs, IGF-receptors, and IGFBPs, IGFBP proteases, IGFBP-RPs, Discovered Five different novel syndromes and several new molecules (4 NEJM papers)

5 What does it take to win a Van Wyk Award? 4. Many many grants More than 60 grants over thirty years >$30,000,000 total Included two CHRC, PO1s Many RO1s

6 What does it take to win a Van Wyk Award? 5. Win a lot of other awards 2014 Judson J. Van Wyk Award, Pediatric Endocrine Society 2014 Human Growth Foundation Award 2013 European Society for Pediatric Endocrinology (ESPE) International Award 2013 J.E. Wallace Sterling Lifetime Alumni Achievement Award, Stanford 2009 Technology/Innovation Award, Oregon Health & Science University 2008 Robert H. Williams Distinguished Leadership Award, The Endocrine Society 2008 Transatlantic Medal, The Society for Endocrinology 2007 Maureen Andrew Mentor Award, SPR-APS 2005 Joseph St. Geme Education Award, Society for Pediatric Research

7 What does it take to win a Van Wyk Award? 6. Helps to be entrepreneurial Inventor on 6 patents 2006 President and CEO, ProteoGenix, Inc President, STAT5, LLC

8 What does it take to win a Van Wyk Award? 7. Give a lot of lectures (>600) and change how people think!

9 What does it take to win a Van Wyk Award? 8. Train a lot of fellows (>70)

10 What does it take to win a Van Wyk Award? 9. Have outside interests

11 Rosenfeld RG: Survival of the Fittest: A Play in Three Acts (2003) Rosenfeld RG: Helios: A Play in Two Acts (2004)

12

13 H-index of Van Wyk Awardees Ron s golf score Ron s h-index Hintz Miller New Blizzard Grumbach Fisher Migeon Crigler RGR

14 What does it take to win a Van Wyk Award? 10. Work family balance

15

16 Pediatric Endocrine Society Ron Rosenfeld Vancouver May 5, 2014

17 I have been allotted 10 minutes: This is far more than is necessary to summarize my accomplishments But: Is woefully inadequate for giving thanks

18 Raymond Hintz, M.D. Melvin Grumbach, M.D.

19 Vivian Hwa, Ph.D.

20 Plus: All of my former fellows All of my colleagues All of my collaborators All of my family

21 GROWTH Universal feature of multicellular organisms Each species has its own unique pattern Determined by both heredity and environment Growth characteristics determined by evolution through natural selection

22 HUMAN GROWTH VELOCITY CANNOT BE EXPRESSED BY 6 th DEGREE POLYNOMIAL

23 GROWTH FAILURE If one excludes environmental factors, all cases of growth failure will have a molecular basis.

24 LESSONS LEARNED

25 Lessons Learned We are all part of an intellectual continuum Teams and mentors are critical Hire the smartest post-docs and learn from them Collaborate globally Research questions come from patients, colleagues, fellows and the research team Keeping abreast of related fields allows for advances in your own Don t belittle case reports; they can be prismatic Study enough patients; learn to recognize patterns Databases are very useful Be suspicious of the perfect test Be willing to give up on a test, even those you develop Be practical - think outside of the ivory tower We are lucky to be pediatric endocrinologists

26 Lessons Learned Every one in this room is caring or has cared for a patient who is a mystery waiting to be solved

27 All truths are easy to understand once they are discovered. The point is to discover them. Galileo

28 To those of you who have received honors, awards and distinctions, I say, well done. And to those of you who are C students, I say, you, too, can be President of the United States. George W. Bush

through meeting many remarkable individuals who played roles in our subsequent life and influenced my choice of a future career.

through meeting many remarkable individuals who played roles in our subsequent life and influenced my choice of a future career. John F. Crigler, Jr. 2011 Judson J. Van Wyk prize, an award of the Pediatric Endocrine Society for career achievement in pediatric endocrinology -Accepting comments May 1, 2011 References for these comments

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