THE FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE
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3 THE FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE
4 Funded Projects Funded Projects Per Fiscal Year
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9 What Has Been Clinical and Translational Research? 9
10 Expanded Definition of Clinical and Translational Research T1 translational research involves theoretical knowledge about a possible intervention. T2 translational research involves application of that theoretical knowledge in efficacy studies, resulting in efficacy knowledge about interventions that work in optimal settings. 10
11 Expanded Definition of Clinical and Translational Research T3 translational research involves translation from recommendations or guidelines into actual practice. T3 research involves real-world practice and/or community settings. Practice-based networks Studies of programs like Head Start Patient-provider communication 11
12 Expanded Definition of Clinical and Translational Research T4 research is an extension of T3 research to an entire population. T4 translational research involves populationbase outcomes assessments at the community or population (public health) level 12
13 What Has Been Clinical and Translational Research? 13
14 What Has Been Clinical and Translational Research? 14
15 Current Definition of Clinical and Translational Research 15
16 N Engl J Med, Vol. 344, No. 26 June 28,
17 Classic Academic Medical Center Clinical Research Large tertiary centers Limited patient numbers Skewed patient populations Skewed clinical skills of academic investigators Extrapolation of results from limited patient settings to real world of day-today practice 17
18 Practice-Based Research Network Studies Occur where most patients receive most of their care Identify problems in everyday practice that create gaps between care recommendations and delivery Test interventions in real world settings Can function as the laboratories to test system improvements in medical care 18
19 FSU COM Mission Statement The Florida State University College of Medicine will educate and develop exemplary physicians who practice patientcentered health care, discover and advance knowledge, and are responsive to community needs, especially through service to elder, rural, minority, and underserved populations.
20 FSU COM Mission Statement The Florida State University College of Medicine will educate and develop exemplary physicians who practice patientcentered health care, discover and advance knowledge, and are responsive to community needs, especially through service to elder, rural, minority, and underserved populations.
21 Florida State University College of Medicine Regional and Rural Campuses
22 Setting Up the Network Institutional commitment at all levels Strong leadership Carefully designed structure within the Office of Research Communication between Network organization and Clinical Faculty (Practices) 22
23 Key Positions in the FSU COM Translational Science Initiative Senior Associate Dean for Research Clinical (Translational) Research Advisory Committee Director of Translational Science Laboratory Director of the Clinical Research Network Regional Campus Dean for Research 23
24 Senior Associate Dean for Research Clinical (Translational) Research Advisory Committee Director of Translational Science Laboratory Research Coordinators Director of the Clinical Research Network Regional Campus Dean for Research Clinical Research Network Regional Campus Faculty Practices 24
25 Attributes of Successful Networks Bridge between practice and academia Conduct meaningful by feasible projects in the practice setting Not disruptive of full time practice Improve quality of care Provide useful service(s) to physicians and patients J Am Board Fam Med 23:
26 Network Physician Perceived Advantages in Participation Competence Intellectual stimulation Practicing physician as the clinical scientist Autonomy Enjoying research without academic work-life hassles Relatedness Positive influence from academic mentors Belonging to a group of individuals with like-minded goals Potent antidote to perceived intellectual isolation of the practitioner J Am Board Fam Med 23:
27 Physician Perceived Incentives Study of 185 network physicians in the Rochester, NY area Internal Medicine Family Medicine Pediatrics JABFM 23: ,
28 Physician Incentives *p<0.05 (IM; FM; Peds) JABFM 23: , 2010 Incentive Opportunity for quality improvement Percent stating important to their participation 77.8 Contribute to clinical knowledge 75.1 Intellectual stimulation 65.4 Interaction with colleagues on research issues 52.4 Academic recognition 36.2 *Opportunity to shape research questions, publication, authorship 35.1 (28.6; 54.1; 32.1) *Additional income source 30.4 (41.4; 24.3; 23.4) Recognition from colleagues 21.2 Recognition from patients
29 Setting the Network Recruitment Engagement Retention Start with doable project(s) as the demonstration 29
30 University of Florida CTSI Goal 1: Promote collaborative partnerships with communities Principles of community-based participatory research Development of practice-based networks Funding pilot studies Formation of Advisory Council 30
31 FSU-UF Community Research Collaborative Program (CRCP) UF translational researchers and the FSU Clinical Research Network New Florida Clustering Award Program Community-based projects Populations Public health Involve students and physician-student teams The pilot projects to inaugurate the FSU CRN 31
32 CRCP Project Health Risk Assessment in Primary Care Community Identify current practices assessing diet, exercise, obesity, alcohol, and tobacco use Pilot use of existing reliable health risk assessment tools in private practice using new information technology (Easily accessible and functional database with practice applications using i-pad) Using same technology to promote care guidelines 32
33 Initial CRCP Project Concussion-Traumatic Brain Injury Management Develop a community-based network for clinical management and research in pediatric head injury Utilize a proven, evidence-based tool for sports related head injury assessment that applicable to the practice office setting 33
34 Initial CRCP Projects Tests the usage of established clinical tools in the real world setting Provides value to the practice and the patient Sets the baseline for future development of newer and novel clinical tools 34
35 Future Network Growth after the CRCP Studies Studies in additional practice settings Primary care emphasis to start Feasibility Synergies Increasing scope over time Planning, personnel, funding, and patience are needed. 35
36 Research Network Potentials Psychosocial Humanities Medical Education Center for Medicine and Law Biomedical projects Biorepository/biomarkers Subspecialty projects Clinical trials 36
37 37
38 Revisions Rejected Approved 38
39 Final Thoughts Impressive research expansion for an upstart medical school Maintain and continue to expand the T-1 research base New frontier Utilization of our distributed, community-based model (T-2 T-4) 39
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