FULCVR Some parts of regimen
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1 Disease Group APPROVED REGIMENS TO BE ADMINISTERED IN L4 SITE AC AC DOCE AC DOCE+TRAS AC AC (DD) AC (DD)+TRAS AC AC +TRAS AC +TRAS (RT W) CMF(PO) CMF(PO)+TRAS DOCETRAS CYCLDOCE CYCLDOCE+TRAS FEC100 FEC D FEC D+TRAS +TRAS TRAS PCV CAPE (W) FU ECARBOF ECARBOX ECF ECX FLOX FU(IV CIV)LCVR FULCVR FULCVR(RT) FULCVR(RT GAST) FULCVR(W) MFOLFOX6 COMMENTS Some parts of regimen are concurrent with RTX Some parts of regimen are concurrent with RTX
2 OXALRALT RALT XELOX FULCV(DEGRAMONT) BEP(3D) BEP(5D) ETOP(5D) CMV MVAC MVAC(HD) (W) BEP(5D) ETOP(5D) DOCE ETOPPAC MTRX MTRX(5D) DOCE DOCEFU ABVD Currently given in L4's per STPT policy. Raltitrexed is high cost and ineligible for NDFP Currently given in L4's per STPT policy. Raltitrexed is high cost and ineligible for NDFP
3 BEACOPP BEND BEND+RITU CEPIOP CEPIOP+RITU If rituximab funded CEPP CEPP+RITU If rituximab funded CEOP CEOP+RITU If rituximab funded CHLO+RITU CHOEP CHOEP+RITU If rituximab funded CHOP CHOP+R CHOP14+R If rituximab funded CNOP COPP CVP+R CYBORD CYCLETOP DANAFARBER(CONT) ETOPMXNT FC FC(PO)+R FC+R FCM FCM+R FLUD(PO)+R FLUD+R GDP GDP+RITU If rituximab funded would need to be private POMP RITU RITU(MNT) CEPP(B) ADOC ETOP ETOP(PO) PEME VINO VINO(MOD) VINO(W) VNBL
4 PEME VINO VNBL (PO) DOCE DOCE MTRXVINO MTRXVNBL VAC ALL R3(MNT C8) OPPA COPP OEPA COPDAC CALGB8811(LATE INT) L4 potential; would need training for cytarabine CALGB8811(MNT) AC CAPE+TRAS CAPEDOCE (W) CMF(PO) CMF(PO)+TRAS DOCE DOCE(W) DOCE+PERT+TRAS DOCE+TRAS DOCE (W) EPIR EPIR(W) FAC FEC50 +PERT+TRAS +TRAS +PERT+TRAS +TRAS PMDR
5 TRAS VINO VINO+TRAS ZOLE PERT+TRAS VNBL PCV VNCR ADOC CAP CAV DOCE ETOP(PO) PEME RALT VINO DOCE (PO) PEME RALT VINO Procarbazine/lomustine are oral components of this regimen and are routinely dispensed at LRCP pharmacy due to availability. This would happen in conjunction with the patient's clinic appointment. IV component (vincristine on days 1 and 22) can be given in L4 satellites.
6 DOCE DOCE(W) PEME TOPO VAC VINO ZOLE PEME RALT DOCE PEME RALT CYCLTOPO If topotecan NDFP funded DOCE (W) PGLDX Kaposi's only VAC CAPE CAV ETOP ETOPMTTN As long as patient has access to mitotane (oral drug) CMV
7 CYCLDCRBVNCR DOCE DOCE(W) DOCE(W)PRED DOCEPRED MVAC MVAC(HD) MXNTPRED CYCL ZOLE DOCE FU DOCE DOCE(W) MTRX PAC+ETOP(PO) DCRB ETOP
8 CAV TOPO DOCE DOCE (W) PGLDX TOPO TOPO(W) VAC VINO CAPE CAPE CAPE+TRAS CAPE CAV ETOP(PO) +TRAS (W) If eligible for NDFP funding If eligible for NDFP funding If eligible for NDFP funding If trastuzumab eligible for NDFP funding If trastuzumab eligible for NDFP funding
9 FU FU+TRAS DOCE DOCE(W) ECARBOF ECARBOX ECF ECX ELF FLOX FOLFIRI FOLFIRI+BEVA FOLFIRINOX FU FU(CIV) FU(IV CIV)LCVR FU(W) FULCV(DEGRAMONT) FULCVR FULCVR(W) IRIN IRIN(Q2W)+CETU IRIN(Wx4) IRIN+CETU IRINRALT MFOLFOX6 MFOLFOX6+BEVA OXALRALT If trastuzumab eligible for NDFP funding requires prior authorization Historically can give, but raltitrexed not funded high cost, unrecoverable Raltitrexed does carry high wastage. Have done these treatments historically in the absence of ratitrexed funding as long as oxaliplatin funded
10 PNTM RALT TRAS If NDFP eligible (e.g. with cis/5fu) XELOX XELOX+BEVA Only if oxaliplatin/bevacizumab funded ALEM Only if compassionate supply available ALEM+RITU Only if compassionate supply available BMP Same as VMP BORT CHLVPP COPP CVP CVP(PO) CYBORP CYCL CYCL+RITU If rituximab funded ETOP FLUD PMDR VNBL GDP VNCR ZOLE BORTDEXALENA PAC+ETOP(PO) ECF current process: STPT approval case by case.
11 IRIN XELOX If NDFP/CBCRP funding available for oxaliplatin
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