Medicines availability short-term supply issues Last updated 01/05/18

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1 Short-term supply issues This resource includes availability information on medicines that are reported to have supply issues, with next expected availability within the next three months. This list is updated every week. This resource lists all manufacturers of brands and generics in the UK for each product and the current availability status. Medicines are listed alphabetically by generic name, with a brand name specified where applicable, together with the affected pack size(s), availability status and the manufacturer name. Name, form, strength Pack size(s) Brand (if applicable) Manufacturer Next availability update Zovirax GlaxoSmithKline UK Expected early May 2018 Aciclovir dispersible tablets 200mg (NEW) 25 Ranbaxy Aciclovir powder for solution for infusion Zovirax GlaxoSmithKline UK Expected mid May vials 250mg (NEW) available through AAH Adrenaline solution for injection pre-filled 1 Emerade Bausch & Lomb UK Ltd and Phoenix only disposable devices 150mcg/0.15ml (1 in 1000) 1 Jext ALK Abello Ltd Adrenaline solution for injection pre-filled disposable devices 150mcg/0.3ml (1 in 2000) Adrenaline solution for injection pre-filled disposable devices 300mcg/0.3ml (1 in 1000) 1 and 2 Epipen Jr. Meda Pharmaceuticals Ltd available through Alliance Healthcare only available through Alliance Healthcare only available through AAH 1 Emerade Bausch & Lomb UK Ltd and Phoenix only Packs of 1 in stock and packs of 2 1 and Epipen Meda Pharmaceuticals Ltd unknown available through 2 Alliance Healthcare only 1 Jext ALK - Abello Ltd available through

2 Adrenaline solution for injection pre-filled disposable devices 500mcg/0.5ml (1 in 1000) 1 Emerade Bausch & Lomb UK ltd Alliance Healthcare only available through AAH and Phoenix only Aldactide tablets 50mg 28 Pfizer Expected 1 June 2018 Amlodipine tablets 5mg 28 Dr Reddy s Laboratories Expected end of May 2018 Sandoz Amlodipine tablets 10mg 28 Dr Reddy s Laboratories Expected end of May 2018 Istin Pfizer Sandoz Expected 7 May 2018 AstraZeneca Atenolol tablets 50mg 28 Strides Shasun

3 Azithromycin oral suspension 200mg/5ml 30 mls (NEW) Bisacodyl tablets 5mg 30ml 60, 100, 500 and 1000 Calcium and Ergocalciferol tablets 28 Carbamazepine sugar free oral suspension 100mg/5ml Dipyridamole modified release capsules 200mg Doxycycline dispersible tablets sugar free 100mg (NEW) Zithromax Pfizer Expected 3 May 2018 Sandoz Chanelle Medical Packs of 500 expected July 2018 and packs of 1000 in stock Dr Reddy s Laboratories Genesis Pharmaceuticals Dulcolax Sanofi Expected 8 May 2018 Crescent Zanza Labs 300ml Expected w/e 4 May Persantin Retard Boehringer Ingelheim Attia Dr Reddy s Laboratories Ofcram Focus Expected May Vibramycin D Pfizer Expected w/e 18 May 2018 Duloxetine gastro resistant capsules 60mg 28 Duciltia Aristo Pharma Aspire Expected May 2018 Consilient Health Creo Pharma Dr Reddy s Laboratories Cymbalta Eli Lilly HBS Healthcare Rivopharm Zentiva

4 Expected 2 May 2018 Aspire Eplerenone tablets 25mg (NEW) 28 Creo Pharma Mylan Inspra Pfizer Expected w/e 4 May 2018 Pfizer Zentiva Aspire Eplerenone tablets 50mg (NEW) 28 Creo Pharma Inspra Pfizer Expected w/c 14 May 2018 Pfizer Expected w/e 5 May 2018 Zentiva Expected 28 May 2018 Chanelle Pharma Fexofenadine tablets 180mg 30 Dr Reddy s Laboratories Zentiva Fluoxetine dispersible tablets sugar free Concordia International 28 Olena 20mg (Amdipharm) Expected mid May 2018 Expected 30 April 2018 Laboratories Fluoxetine capsules 60mg 30 Dr Reddy s Laboratories Focus Pharmaceuticals Milpharm Medreich Mylan Fluticasone ointment 0.005% 15g Cutivate GlaxoSmithKline UK Expected late May 2018 Gemcitabine powder for solution for 1 Expected end of July 2018

5 infusion vials 1g Eli Lilly Pfizer (Hospira) Expected 29 June 2018 Sun Pharmaceuticals UK Bilxona Packs of 28 in stock and packs of 56 expected 22 May 2018 Zicron Concordia International 28 and Vamju (Amdipharm) 56 Gliclazide modified release tablets 30mg Glyceryl trinitrate solution for infusion ampoules 25mg/5ml (NEW) Human papillomavirus(type 16,18) vaccine (adsorbed) suspension for injection prefilled syringes 0.5ml Hypromellose eye drops 0.3% Latanoprost eye drops 50mcg/1ml (NEW) Nazdol MR Consilient Health Ziclaseg Lupin Diamicron MR Servier Laboratories Edicil 5 Pfizer Expected w/e 18 May 2018 (Hospital only) 1 Cervarix GlaxoSmithKline UK Expected Quarter ml 2.5ml Blumont Healthcare Vizulize Hypromellose East Midlands Pharma Mandanol M & A Pharmachem Martindale (Hospital only) Lumecare Medicom Healthcare Brolene Cool Eyes Sanofi Expected w/c 25 June 2018 Sai-Meds Expected w/c 20 July 2018 Martindale Pharma Medizol Medicom Healthcare Ltd Xalatan Pfizer Pfizer

6 Latanoprost 50mcg/1ml and timolol 5mg/1ml eye drops 2.5ml Zentiva Expected w/c 7 May 2018 Kent Pharmaceuticals Martindale Xalacom Pfizer Zentiva Expected w/c 14 May 2018 Levodopa/Carbidopa/Entecapone tablets 75/18.5/200mg 30 Sastravi Expected 14 May 2018 Levodopa/Carbidopa/Entecapone tablets 100/25/200mg 30 Sastravi Expected 14 May 2018 Levodopa/Carbidopa/Entecapone tablets 200/50/200mg 30 Sastravi Expected 14 May 2018 Medroxyprogesterone tablets 200mg (NEW) Memantine tablets 10mg 56 Metformin tablets 500mg 28 Mometasone furoate ointment 0.1% 30 Provera Pfizer Expected w/e 11 May g Marixino Consilient Health Crescent Niche Generics Expected July 2018 Expected 11 May 2018 Crescent Milpharm Relonchem Expected 9 May 2018 Glenmark Merck Sharp & Dohme

7 Mylan Expected mid July 2018 Ondansetron tablets 4mg 30 Novartis Oxybutynin tablets 2.5mg 56 and Niche Generics Expected early June Ditropan Sanofi Strides Shasun Oxybutynin tablets 5mg 56 and Niche Generics Expected early June Ditropan Sanofi Strides Shasun Expected 30 April 2018 Phenoxymethylpenicillin oral solution Laboratories 100ml sugar free 125mg/5ml Brown & Burk Expected mid May 2018 Kent Pharmaceuticals Quinapril tablets 20mg 28 Accupro Pfizer Expected 25 May 2018 Quinapril tablets 40mg (NEW) 28 Accupro Pfizer Expected w/e 25 May 2018 Ranitidine tablets 300mg 30 Zantac GlaxoSmithKline UK Expected late April 2018

8 Ranitidine solution for injection ampoules 50mg/2ml (NEW) Ranitidine oral solution sugar free 75mg/5ml (NEW) 5 300ml Risperidone tablets 1mg 20 Rizatriptan orodispersible tablets 10mg Salbutamol solution for injection ampoules 5mg/5ml (NEW) 3 and 6 Sildenafil film coated tablets 50mg 8 Tobramycin solution for injection vials 240mg/6ml (NEW) Tolterodine tablets 2mg Expected 11 May 2018 Concordia International Expected w/e 4 May 2018 Zantac GlaxoSmithKline UK Expected early June 2018 Focus GlaxoSmithKline UK Expected mid May 2018 Expected 26 May 2018 Aurobindo Expected 11 May ml Ventolin GlaxoSmithKline UK Expected late May 2018 Expected May 2018 Macleods Expected w/c 30 April 2018 Milpharm Mylan Pfizer Expected 11 May Pfizer Expected end of May Expected end of May 2018 Aspire Expected May 2018 Detrusitol Pfizer

9 Sandoz Expected end of April 2018 Tolterodine modified-release capsules 4mg Preblacon Expected 9 July 2018 (NEW) Neditol Aspire Detrusitol Pfizer 28 Santizor Pfizer Iconex Sandoz Mariosea Blerone Zentiva Tolterodine modified release capsules 4mg 28 Detrusitol XL Pfizer Expected 1 June Santizor XL Pfizer Creo Pharma Tranexamic acid tablets 500mg 60 Manx Healthcare Cyklokapron Meda Pharmaceuticals Rivopharm Sandoz Expected end of July 2018 Vincristine sulphate solution for injection vials 2mg/2ml 5 Pfizer Expected 25 May 2018 Vincristine sulphate solution for injection vials 5mg/5ml 5 Pfizer Expected 15 June 2018 Xylocaine pump spray 10mg/dose 50ml Aspen Expected 20 May 2018

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