Medicines availability long-term supply issues Last updated 10/04/18

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1 Long-term supply issues This resource includes availability information on medicines that are reported to have supply issues, with next expected availability greater than three months or no known date. This list is updated every three months. This resource lists all manufacturers of brands and generics in the UK for each product and the current availability status. Medicines are listed alphabetically by generic name, with a brand name specified where applicable, together with the affected pack size(s), availability status and the manufacturer name. Name, form, strength Pack size(s) Brand (if applicable) Manufacturer Next availability update Acetazolamide modified release capsules Eytazox PR mg Diamox SR Expected Quarter available through Adrenaline solution for injection ampoules 10 Alliance Healthcare only 1mg/1ml (1 in 1000) (NEW) 10 Martindale Pharmaceuticals Ltd Adrenaline solution for injection ampoules 10 Hamel Pharmaceuticals Ltd 10mg/10ml (1 in 1000) (NEW) 10 Martindale Pharmaceuticals Ltd Adrenaline dilute solution for injection ampoules 100mcg/1ml (1 in 10,000) (NEW) 10 Martindale Pharmaceuticals Ltd Adrenaline dilute solution for injection prefilled syringes 100mcg/1ml (1 in 10,000) 10 1 and Aguettant Ltd (NEW) 1 Martindale Pharmaceuticals Ltd Alprostadil urethral stick 250mcg 1 Muse Meda Pharmaceuticals Expected 6 July Muse Meda Pharmaceuticals Amorolfine mediated nail lacquer 5% 2.5ml

2 and 5ml Aspire Amylase/lipase/protease gastro-resistant tablets 5000/5600/330 units Loceryl Galderma Omicur Morningside Temporarily discontinued - unknown Zentiva 300 Pancrex V forte Essential Pharmaceuticals

3 Aspirin/dipyridamole modified release capsules 25mg/200mg Atorvastatin tablets 40mg 28 Celecoxib capsules 100mg Cetrimide/phenethyl alcohol/undecenoic acid shampoo 100 Molita Dr Reddy s Laboratories (Alternative available to order as an unlicensed medicine from IDIS Pharma on , by fax or uk@idispharma.com) Consilient Health Pfizer Lipitor Pfizer Ranbaxy Wockhardt 30 and ml and 500ml Ceftazidime injection vials 500mg 1 Zentiva Novartis Brown & Burk Pfizer Temporarily discontinued - unknown Ceanel concentrate Alliance Pharmaceuticals Bowmed Ibisqus Fortum GlaxoSmithKline UK Expected Quarter Ceftazidime injection vials 1g 1 Fortum GlaxoSmithKline UK Expected Quarter Ceftazidime injection vials 2g 1 Fortum GlaxoSmithKline UK Expected Quarter Ceftazidime injection vials 3g 1 Fortum GlaxoSmithKline UK Expected Quarter

4 Chlorhexidine gluconate gel 0.5% 30g Cepton clear gel Boston Healthcare Chloramphenicol eye drops 0.5% 10ml Martindale Chlorpromazine tablets 25mg 28 Dr Reddy s Laboratories Genesis Chlorpromazine tablets 100mg 28 Dr Reddy s Laboratories Expected July 2018 Genesis Pharmaceuticals Cimetidine tablets 200mg (Alternative available to order as 60 and an unlicensed medicine from IDIS 120 Tagamet Chemidex Pharma on , by fax or uk@idispharma.com) Essential Generics Cimetidine tablets 400mg 60 and 120 Tagamet Chemidex Pharma Ennogen Essential Generics Tillomed (Alternative available to order as an unlicensed medicine from IDIS Pharma on , by fax or uk@idispharma.com)

5 Clindamycin capsules 300mg 30 Clindamycin alcoholic solution 1% Co-amoxiclav powder for solution injection vials 500mg/100mg Co-codamol effervescent tablets sugar free 15mg/500mg Co-trimoxazole solution for infusion ampoules 160mg/800mg/10ml 30ml and 50ml 10 Dalacin T topical solution Rivopharm Pfizer Expected mid 2019 Bowmed Ibisqus Augmentin GlaxoSmithKline UK Wockhardt 4 x 25 Codipar 5 Aspen Expected 9 August 2018 Colestipol granules 5g 30 Colestid Pfizer Cophenotrope tablets 100 Concordia international Diazepam rectal tubes 10mg/2.5ml 5 Diazepam RecTubes Wockhardt Digoxin solution injection vials 250mcg 10 x 2ml Diclofenac tablets enteric-coated 50mg 84 Dopamine concentrate solution for infusion 40mg/ml 10 x 5ml Duloxetine gastro resistant capsules 30mg 28 Concordia international Dexcel Pharma Duciltia Aristo Pharma Aspire Consilient Health

6 Emulsifying ointment 500g Enalapril tablets 2.5mg 28 Enalapril tablets 5mg 28 Enalapril tablets 10mg 28 Enalapril tablets 20mg 28 Eprosartan tablets 300mg 28 Dr Reddy s Laboratories Cymbalta Eli Lilly HBS Healthcare Rivopharm Zentiva Ecolab Healthcare Information unavailable Pinewood Dexcel Pharma Innovace Merck Sharp and Dohme Dexcel Pharma Innovace Merck Sharp and Dohme Milpharm Dexcel Pharma Innovace Merck Sharp and Dohme Milpharm Dexcel Pharma Milpharm Innovace Merck Sharp and Dohme Temporarily discontinued - unknown Teveten

7 Erythromycin ethyl succinate tablets 500mg 28 Erythroped A Estradiol/levonorgestrel transdermal patches 50mcg/10mcg/24hours 4 and 12 Femseven Sequi Ferrous fumarate tablets 322mg 28 Fludroxycortide ointment % 60g Typharm Flumetasone/Clioquinol ear drops 0.02%/ 1% 7.5ml and 10ml Expected Quarter Fluocinolone cream % 50g Synalar 1 in 10 cream Reig Jofre Fluvoxamine tablets 50mg Fluvoxamine tablets 100mg Forceval capsules Ganirelix solution for injection pre-filled syringes 250mcg/0.5ml Ganirelix acetate solution for injection prefilled syringes 250mcg/0.5ml Gentamicin solution for injection ampoules 80mg/2ml 30 and and 60 15, 30 and 90 1 and 5 1 and 5 28 and 56 Faverin Tillomed Wockhardt Faverin Tillomed Wockhardt Alliance pharmaceuticals Packs of 15 and 30 in stock Packs of 90 is unknown Orgalutran Merck Sharp and Dohme Expected November 2018 Fyremadel Ferring Pharmaceuticals (Hospital only) Cidomycin Sanofi Wockhardt Gliclazide modified release tablets 28 and Bilxona

8 30mg 56 Zicron Vamju Nazdol MR Consilient Health Gliclazide modified release tablets 60mg Glipizide tablets 5mg 28 and and 56 Ziclaseg Lupin Diamicron MR Servier Laboratories Edicil Bilxona Vamju Packs of 28 in stock and packs of 56 unknown Laaglyda Consilient Minodiab Pfizer Griseofulvin spray 1% 20ml Grisol AF spray Transdermal Hepatitis A inactivated vaccine pre-filled syringe Human papillomavirus (type16,18) vaccine (adsorbed) suspension for injection prefilled syringes 0.5ml Hydrocortisone sodium phosphate solution for injection 100mg/1ml Hydrocortisone sodium phosphate solution for injection 500mg/1ml 1 and 10 Havrix GlaxoSmithKline Avaxim Sanofi Pasteur VAQTA Merck Sharp and Dohme 1 Cervarix GlaxoSmithKline UK 5 5 Expected Quarter Expected Quarter Hydrocortisone acetate aerosol 10% 20.8g Colifoam Meda Pharmaceuticals Expected mid 2018 Hydrocortisone acetate injection 25mg/1ml 10 Hydrocortistab

9 Hydrocortisone/urea cream 1%/10% 30g and 100g Irbesartan tablets 150mg 28 Irbesartan tablets 300mg 28 Alphaderm cream Alliance Pharmaceuticals Ifirmasta Consilient Health Lupin Milpharm Aprovel Sanofi Torrent Pharma Expected Quarter Ifirmasta Consilient Health Lupin Milpharm Aprovel Sanofi Kaolin and morphine mixture BP 200ml Care Thornton & Ross Dr Reddy s Laboratories Lacidipine tablets 2mg 28 Motens GlaxoSmithKline Dr Reddy s Laboratories Lacidipine tablets 4mg 28 Motens GlaxoSmithKline Molap Rivopharm Lacri-lube eye ointment 3.5g and 5g Allergan Lansoprazole orodispersible tablets 15mg 28 Zoton Pfizer

10 Levetiracetam oral solution sugar free 100mg/ml 300ml Levetiracetam tablets 750mg 60 Levetiracetam tablets 1000mg 60 Linezolid tablets 600mg 10 Ranbaxy Consilient Health Desitrend Desitin Pharma Rosemont Pharmaceuticals (Hospital only) Thame Laboratories Consilient Rivopharm Keppra UCB Pharma Zentiva Consilient Lupin Rivopharm Keppra UCB Pharma Zentiva Dr Reddys Laboratories Zyvox Pfizer Sandoz

11 Wockhardt Lisinopril tablets 2.5mg 28 Relonchem (on behalf of Genus) Lorazepam tablets 1mg 28 Genesis Morningside Losartan tablets 25mg 28 Genesis Pharmaceuticals Cozaar Merck Sharp and Dohme Sandoz Losartan tablets 50mg 28 Genesis Pharmaceuticals Cozaar Merck Sharp and Dohme Sandoz Losartan tablets 100mg 28

12 Memantine tablets 10mg 28 Memantine tablets 20mg 28 Consilient Health Cozaar Merck Sharp and Dohme Sandoz Marixino Consilient Crescent Dr Reddy s Laboratories Ebixa Lundbeck Niche generics Marixino Consilient Health Crescent Dr Reddy s Laboratories Ebixa Lundbeck Niche Generics Menadiol tablets 10mg 100 Alliance Pharmaceuticals Expected Quarter Meningococcal oligosaccharide A,C,W135 and Y vaccine powder and solvent for solution for injection vials 1 x 0.5ml Menveo GlaxoSmithKline Expected Quarter Meropenem powder for solution for 10 Fresenius Kabi

13 injection vials 500mg/20ml Kent Pharmaceuticals Meropenem powder for solution for injection vials 1g/30ml Mirtazapine orodispersible tablets 30mg Mirtazapine orodispersible tablets 45mg Morphine tartrate/cyclizine tartrate injection 10mg/50mg x 1ml Pfizer (Hospira) Fresenius Kabi Kent Pharmaceuticals Pfizer (Hospira) Focus Pharmaceuticals Zispin SolTab Merck Sharp and Dohme Milpharm Focus Zispin SolTab Merck Sharp and Dohme Milpharm Cyclimorph 10 Mupirocin cream 2% 15g Bactroban GlaxoSmithKline Expected Quarter Nifedipine modified release tablets 10mg 56 Adalat Retard Bayer Adipine Chiesi Ennogen Ethigen Tensipine Thornton & Ross

14 Nifedipine modified release tablets 40mg 28 Pericyazine tablets 10mg 84 Phenobarbital tablets 15mg 28 Prednisolone Acetate suspension for injection 25mg/1ml Quinapril tablets 10mg 28 Rabeprazole tablets 10mg 28 Rabeprazole tablets 20mg Fortipine LA Ennogen Ennogen Zentiva Accupro Pfizer Expected Quarter Pariet Eisai Milpharm Consilient Pariet Eisai Milpharm Rasagiline tablets 1mg 28

15 Rivastigmine transdermal patches 9.5mg/24 hours Rivastigmine transdermal patches 13.3mg/24 hours Simple eye ointment g Aristo Pharma Dr Reddy s Laboratories Flynn Pharma HBS Pharma Rivopharm Azilect Alzest Dr Reddys Laboratories Voleze Focus Exelon Novartis Almuriva Sandoz Voleze Focus Exelon Novartis Erastig Martindale Sodium fluoride oral drops 0.37% 60ml Endekay fluodrops Manx Healthcare Ltd Sodium fluoride mouthwash sugar free 2% 100ml Endekay fluorinse Manx Healthcare Ltd Sotalol tablets 40mg 28 Tillomed Sotalol tablets 80mg 28 and 30 Sotacor Myers Squibb

16 Tillomed Sucralfate suspension sugar free 1g/5ml 250ml Antepsin suspension Chugai Pharma (An alternative is available to order as an unlicensed medicine from IDIS Pharma on , by fax or Sucralfate tablets 1g 50 Antepsin tablets Chugai Pharma (An alternative is available to order as an unlicensed medicine from IDIS Pharma on , by fax or Sulfasalazine enteric coated tablets 500mg 112 Salazopyrin EN Pfizer Migraitan Laboratories Sumatriptan tablets 50mg 1,2,6 Aurobindo Pharma Ltd Expected Quarter Terbinafine tablets 250mg Consilient Health 14 and Dr Reddy s Laboratories 28 Medreich Lamisil Novartis Relonchem Testosterone gel unit dose tube 50mg/5ml 30 x 5g Testim Ferring Pharmaceuticals Testosterone gel unit dose sachets 50mg/5ml 30 Testogel Besins Healthcare Tetrahydrofurfuryl salicylate/ethyl Tranvasin heat rub 40g nicotinate/hexyl nicotinate rub cream Thornton & Ross

17 14%/2%/2% Ticarcillin/clavulanic acid injection 3.2g 4 Timentin GlaxoSmithKline Tobramycin injection ampoules 80mg/2ml 10 UK Tolterodine tablets 1mg 56 Trifluoperazine tablets 1mg 112 Trifluoperazine tablets 5mg 112 Trimethoprim oral suspension sugar free 50mg/5ml 100ml Aspire Detrusitol Pfizer Pfizer Sandoz Ennogen Ennogen Expected Quarter (Alternative available to order as an unlicensed medicine from IDIS Pharma on , by fax or uk@idispharma.com) Expected Quarter (Alternative available to order as an unlicensed medicine from IDIS Pharma on , by fax or uk@idispharma.com) Monotrim Chemidex Pinewood Typhoid polysaccharide vaccine pre-filled 1 and Typhim Vi Sanofi Pasteur

18 syringe 10 Viatim Sanofi Pasteur Venlafaxine tablets 37.5mg 28 and 56 Dexcel Pharma Ltd

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