ON LINE REGISTRATION

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1 Montreal, April 30 May 2, 2015 Centre Mont-Royal, 2200 Mansfield Street, Montreal (Quebec) H3A 3R8, Canada INFORMATION: ON LINE REGISTRATION CONTACT: Susanne Knoepfel : Tel (514) ext 4605, sknoepfel@jgh.mcgill.ca

2 Speakers Julio Garcia Aguilar, Memorial Sloan Kettering Cancer Center, New York, USA Carmen J Allegra, University of Florida, FL (TBC), USA Gerald Batist, Jewish General Hospital,, Montreal, Canada Geerard Beets, Maastricht University, Netherlands Kathleen Belley, Chief Technologist, Jewish General Hospital,, Montreal, Canada Alexandre Bouchard, Centre Universitaire de Québec, Québec, Canada Gina Brown, The Royal Marsden, UK Krzysztof Bujko,Maria Sklodowska-Curie Memorial Cancer Centre, Gliwice, Poland Bernard Cummings, Princess Margaret Hospital, Toronto, Canada Mark Davies, Patient Advocate Conor P Delaney, University Hospitals Case Medical Center, Cleveland, Ohio, USA Suzanne Fontaine, Hôpital St-Luc, Centre Hospitalier de l Université de Montréal, Canada Benoit Gallix, Chair or Radiology,, Montreal, Canada Jean-Pierre Gerard, Centre Antoine Lacassagne, Nice, France Angelita Habr-Gama, University of São Paulo School of Medicine, Brazil Anders Jakobsen, Vejle Hospital, Denmark John Marks, Lankenau Medical Center and Institute for Medical Research, Pennsylvania, USA Emanuele Lezoche, University of Ancona, Rome, Italy Sender Liberman, Health Centre, Montreal, Canada Corrie Marijnen, Leiden University, Netherlands Sylvain Martel, Institute of Biomedical Engineering, École Polytechnique de Montréal (EPM) John Monson, University of Rochester Medical Center, USA Remi Nout, Leiden University, Netherlands Lars Pahlman, University of Uppsala, Sweden Rodrigo Perez, University of São Paulo School of Medicine, Brazil Terry Phang, St. Paul s Hospital, The University of British Columbia, Canada Salvatore Pucciarelli, University of Padova, Italy Philip Quirke, Leeds Institute of Cancer & Pathology, UK Carole Richard, Centre Hospitalier de l Université de Montréal, Canada Lawrence Rosenberg, Executive Director, Jewish General Hospital,, Canada Eric Rullier, CHU Hôpitaux de Bordeaux, France Harm Rutten, Maastricht University, Netherlands David Sebag-Montefiore, Leeds institute of Cancer and Pathology, University of Leeds, UK Fraser Smith, North Cumbria University Hospitals NHS Trust, UK William Song, Medical Physics, Sunnybrook Health Sciences Centre, Toronto, Canada Barry Stein, President of the Colorectal Cancer Association of Canada Arthur Sun Myint, University of Liverpool, UK Vincenzo Valentini, Università Cattolica del Sacro Cuore, Rome, Italy Cornelis Van de Velde, Leiden University, Netherlands Veronique Vendrely, CHU Hôpitaux de Bordeaux, France Té Vuong, Jewish General Hospital,, Montreal, Canada Online abstract submission is now open for short oral presentations. Please submit abstracts by January 31, 2015: jghradiationoncology@gmail.com

3 Centre Mont-Royal, 2200 Mansfield Street, Montreal (Quebec) H3A 3R8, Canada Thursday, April 30, :00 08:10 Welcome Gerald Batist and Lorrie Rosenberg 08:10 08:15 Agenda of the meeting Té Vuong 08:15 08:20 Case Presentation Sender Liberman Socio-economics of colo-rectal cancer Moderator: DrLPahlman and C. Richard 08:25 08:40 Epidemiology 08:45 09:00 RT and Surgery C Van de Velde 09:05 09:20 How to select patients with locally advanced rectal H Rutten cancer for total or partial organ preservation 09:25 09:40 TME Standard surgery and importance of national John Monson wide data-base 09:45 10:00 Nation based tumor registry Lars Pahlman 10:05 10:20 Impact of colo-rectal cancer after 10 years of colorectal P Quirke cancer screening 10:20-10:40 Questions 10:40 11:00 Coffee break Surgery (indications and limits) Moderators: Dr S Liberman and Dr H Rutten 11:00 11:15 TME surgery and functional results Terry Phang 11:20 11:35 Functional results post HDRBT C Richard 11:40 11:55 Endoscopic surgical options for early rectal Tumors Conor P Delaney Tumor Imaging Moderators: Dr Oliver Chagnon/ Vincent Pellser 12:00 12:15 Imaging modalities for early and advanced rectal Gina Brown tumors: Which ones are best? 12:20 12:35 Post neoadjuvant CT-RT evaluation Benoit Gallix 12:40 12:55 Role of PET scan in the post treatment evaluation R Perez 12:55 13:15 Questions 13:15 14:15 Lunch The patient perspectives Moderators: Barry Stein/ G Beets 14:30 14:45 Québec patients perspectives: APR/coloanal/LAR C Richard 14:50 15:05 15:10 15:25 The non surgical option ( Quebec/UK) Medico-legal issues related to treatment choices A Fontaine/M Davies Barry Stein Moderators : Drs T Niazi/ V Valentini 15:30 15:45 Is adenocarcinoma of the rectum radio-resistant? Anders Jakobsen 15:50 16:05 Radiation therapy as a curative modality JP Gerard 16:10 16:25 Contact X-ray brachytherapy as a boost, does it work? Arthur SMyint 16:30 16:45 McGill s Experience R Nout 16:50 17:05 The Hebert trial C Marijnen 17:05 17:20 Questions Moderators : DrsDr Monson/ R Nout/ K Bujko 17:20 18:00 Case Discussions All participants 19:30 Dinner

4 Friday, May 1, 2015 Treatment alternatives to standard surgery Moderators: Drs Van de Velde/ J Marks 08:00 08:15 The TREC study (UK) Dr David Sebag Montefiore 08:20 08:35 The Carts study C Marinen 08:40 08:55 Early T2 tumors E Lezoche 09:00 09:15 The leader trial S.Pucciarelli 09:20 09:35 Julio Garcia Aguilar (USA) 09:40 09:55 Polish Experience K Bujko 10:00 10:15 Greccar 2 study V Vendrely 10:15 10:30 Coffee Break TEM related toxicities and neoadjuvant RT Moderators: Drs J Monson/Boutros 10:30 10:45 TEM related toxicities and neoadjuvant RT John Marks (Philadelphia) 10:50 11:05 Italian experience E Lezoche 11:10 11:25 Post TEM surgery R Perez 11:30 11:45 Pro and cons local excision vs Observation Eric Rullier (Bordeaux) 11:50 12:05 TEM for early cancer - Quebec experience Alexandre Bouchard 12:05 12:30 Questions 12:30 13:30 Lunch Defining complete responders Moderators: Dr J G Aguilar/ L Pahlman 13:30 13:45 Definition, timing and significance of complete response after chemotherapy and radiation AngelitaHabr-Gama 13:50 14:05 Defining complete response in 2015; is it time for a rethink? Fraser Smith 14:10 14:25 Watchful waiting for a clinical complete response after chemoradiation G Beets 14:30 14:45 The French experience JP Gerard 14:50 15:05 Salvage after watch and wait strategy A Habr-Gama Future trials Moderators: Drs Sender Liberman/ Dr R Nout/ R Perez 15:10 15:25 Opera trial JP Gerard 15:30 15:45 Greccar 12 E Rullier 15:50 16:05 US trial JG Aguilar 16:05 16:30 Questions 16:30 17:00 Coffee Break Case Discussions Moderators: Dr N Morin/ J Marks /J P Gerard 17:00 18:00 Case Discussions All participants

5 Saturday, May 2, 2015 Predictive models to radiation response and New radiation modalities Moderators: D Sebag Montefiore and B Cummings 08:00 08:15 Nanorobotic project S Martel 08:20 08:35 Molecular predictors of radiation response R Perez 08:40 08:55 Radiomics and prediction of pcr: state of art and new V Valentini developments 09:00 09:15 Intensity Modulated Brachytherapy W. Song 09:15 09:30 Questions 09:30 10:00 Coffee Break Timing between Chemotherapy and radiation Therapy Moderators: TBD 10:00 10:15 Kir study: Optimizing chemotherapy timing T Vuong 10:15 10:30 Role of Adjuvant Chemotherapy in Early-Stage Rectal Cancer C Allegra 10:30 12:00 Oral papers / poster sessions 9:00 11:00 Imaging workshop (G Brown /B Gallix / Frederick Desjardins) 12:00 Closing Remarks Workshops, scientific posters, oral presentations

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