Breeding Soybeans with a Robust Trait Pipeline. Rick Leitz February 22, 2010 Monsanto Company

Size: px

Start display at page:

Download "Breeding Soybeans with a Robust Trait Pipeline. Rick Leitz February 22, 2010 Monsanto Company"

Nathaniel Higgins
6 years ago
Views:

1 Breeding Soybeans with a Robust Trait Pipeline Rick Leitz February 22, 2010 Monsanto Company

2 2009 Growing Season Review The central US experienced one of the coolest and wettest summers on record White mold in Illinois, Iowa, Indiana and Ohio White Mold Incidence Map

Final Yield Data Confirms Genuity TM Roundup Ready 2 Yield Soybean Delivers RELATIVE MATURITIES 1 4 COMPARISONS: >40,000 APPROXIMATE BU/ AC ADVANTAGE FOR ROUNDUP READY 2 YIELD: 3.

3 Final Yield Data Confirms Genuity TM Roundup Ready 2 Yield Soybean Delivers RELATIVE MATURITIES 1 4 COMPARISONS: >40,000 APPROXIMATE BU/ AC ADVANTAGE FOR ROUNDUP READY 2 YIELD: 3.6 BUSHELS PER ACRE PERCENT YIELD ADVANTAGE FOR ROUNDUP READY 2 YIELD 1 : 7.1% Genuity TM Roundup Ready 2 Yield Competitive Products with Roundup Ready Trait Genuity Roundup Ready 2 Yield 2009 Trials Combine For 7+ Percent Over Competitive Roundup Ready in Three Year Summary Three year summary ( ) of head-to-head comparisons between all Roundup Ready 2 Yield products available for sale in 2010, includes Class of 2009 and advancement Class of 2010 products versus national competitive Roundup Ready products as of November 21, Source: Includes all breeding and commercial strip trial data data includes maturity groups 1, 2, 3 and 4. All head to head comparisons are within +/ 0.4 day maturity. Data is weighted equally by year.

2 bu 81% wins 77% wins IA South 4.8 bu 84% wins MO/KS East 4.3 bu 78% wins Delta West 5.2 3.4M bu 77% (4%) wins WI/IL N. 3.8 bu 9M 80% wins (12%) IL Central 4.0 bu 76% wins IL South 5.

4 Class of 2010 Genuity TM Roundup Ready 2 Yield Advancements Deliver Outstanding Results ND/MN North 4.3 bu 83% wins SD 3.6 bu 79% wins GEOGRAPHIC BREAK DOWN: GENUITY TM ROUNDUP READY 2 YIELD NE East 3.6 bu 71% wins MN West 4.2 bu 80% wins MN East 3.8 7M bu 82% (9%) wins IA West 10M IA East 4.7 bu (13%) 4.2 bu 81% wins 77% wins IA South 4.8 bu 84% wins MO/KS East 4.3 bu 78% wins Delta West M bu 77% (4%) wins WI/IL N. 3.8 bu 9M 80% wins (12%) IL Central 4.0 bu 76% wins IL South 5.6 bu 81% wins Delta East 6.2 bu 77% wins 1.9M (2.5%) MI/OH 4.5 bu 81% wins 5.4M (7%) IN North 4.4 bu 79% wins KY/S. IN/ OH 4.0 bu 70% wins Northeast 7.9 bu 92% wins Advancement Class of GENETIC BANDWIDTH AND DIVERSITY EXPANDS RAPIDLY 2009 <15 varieties 2010 >125 candidate varieties 2011 >1200 candidate varieties Advancement Class of 2010 represents Roundup Ready 2 Yield varieties to be deployed in their projected sales geographies. Comparisons are between Class of 2010 versus national competitive Roundup Ready products as of Nov. 21, Data includes breeding and commercial strip plot data. Seed treatments are equivalent in every individual head to head comparison. 1. Class of 2010 advancements represents Roundup Ready 2 Yield varieties to be deployed in their projected sales geographies. Comparisons are between Class of 2010 versus national competitive Roundup Ready products as of Nov. 21, 2009.

Class of 2011 Genuity Roundup Ready 2 Yield Soybeans Show Promise to Deliver Additional Advantage Versus Class of 2010 Genuity TM Roundup Ready 2 Yield Breeding Pipeline 2011 >1200 candidate

5 Class of 2011 Genuity Roundup Ready 2 Yield Soybeans Show Promise to Deliver Additional Advantage Versus Class of 2010 Genuity TM Roundup Ready 2 Yield Breeding Pipeline 2011 >1200 candidate varieties > 1.1bu/acre over Class of 2010 > 59%Win Rate > 28,000 Comparisons *Head to head comparisons from breeding trials between Class of 2011 candidates and Class of 2010 advancements as of Nov. 21, 2009.

SOYBEANS HIGHER YIELDING SOYBEANS DICAMBA TOLERANCE VISTIVE GOLD OMEGA-3 SOYBEANS 2010+ GENUITY ROUNDUP

6 Soybean Pipeline Products Designed to Provide Additional Grower Benefits 2 ND -GEN HIGHER YIELDING SOYBEANS HIGH-STEARATE SOYBEANS S0YBEAN-CYST NEMATODE RESISTANCE RUST TOLERANT SOYBEANS APHID-RESISTANT SOYBEANS HIGHER YIELDING SOYBEANS DICAMBA TOLERANCE VISTIVE GOLD OMEGA-3 SOYBEANS GENUITY ROUNDUP READY 2 YIELD Commercialization Depends on Many Factors, Including Successful Conclusion of Regulatory Process

2008/2009 Crop Year Medium Insect Pressure - 5 Sites Insecticide reduction Weed-control system performance 11% Yield improvement from

7 Insect-Protected Genuity Roundup Ready 2 Yield Advances to Phase 4, Ushering In International Soybean Trait Platform St. Helena de Goias, Brazil January 2009 Roundup Ready Soybeans Insect-Protected Roundup Ready 2 Yield Soybeans Initial Yield Results 2008/2009 Crop Year Medium Insect Pressure - 5 Sites Insecticide reduction Weed-control system performance 11% Yield improvement from Roundup Ready 2 Yield and insect control trait Discovery Phase 1 Phase 2 Proof of Concept Early Development Phase 3 Adv. Development Phase 4 Pre-Launch Launch

Dicamba-Tolerant Soybeans Expected to Provide the Most Effective Weed Management System Improved weed control options with two modesof-action.

Low residues of dicamba and dicamba metabolites may simplify registration of dicamba for over-thetop use.

8 Dicamba-Tolerant Soybeans Expected to Provide the Most Effective Weed Management System Improved weed control options with two modesof-action Southern Illinois University Trials Roundup plus dicamba provides excellent control of hard to control weeds and glyphosatetolerant weeds. Low residues of dicamba and dicamba metabolites may simplify registration of dicamba for over-thetop use. Non-treated Control Dicamba at 8 oz/a tank mixed with 22 oz/a of Roundup WeatherMax on RR2Y/dicamba-tolerant soybeans Discovery Phase 1 Proof of Concept Phase 2 Early Development Phase 3 Adv. Development Phase 4 Pre-Launch Launch

Higher-Yielding Soybeans Showed Improved Yield Across Five Seasons of Broad-Acre Yield Trials Intrinsic yield improvement through insertion of key genes Lead event shows an average yield advantage of

9 Higher-Yielding Soybeans Showed Improved Yield Across Five Seasons of Broad-Acre Yield Trials Intrinsic yield improvement through insertion of key genes Lead event shows an average yield advantage of 7 percent over controls in metaanalysis across 5 seasons of testing in 95 environments Developing regulatory data for phase advancement AVERAGE YIELD ADVANTAGE (BU/ACRE) Higher-Yielding Soybeans Outperform Controls In North And South American Trials Season 1 Season 2 Season 3 Season 4 Season 5 Cross-Season Average US 07 LAS US 08 LAS US 09 Summary Locations % Win 67% 100% 87% 85% 82% 84% Product Concept Yield Benefit Target Range COLLABORATION WITH Discovery Phase 1 Proof of Concept Phase 2 Early Development Phase 3 Adv. Development Phase 4 Pre-Launch Launch

10 SDA Omega 3 Soybean Oil Provides a Sustainable Source of Omega 3 s in Human Diet PRODUCT CONCEPT: Provide consumer health benefit (cardiovascular) Improve food product performance (taste and shelf life) Preferred sustainable source of omega 3 in food (flexible supply) Fatty Acid Composition (%) 16:0 Palmitic 18:0 Stearic 18:1 Oleic 18:2 Linoleic 18:3 Linolenic 18:4ω3 SDA Commodity Soy Key Food Applications Oil Based Foods Dairy Products Snack Foods Beverages Baked Goods Prepared Foods Increase Omega-3 Discovery Phase 1 Proof of Concept Phase 2 Early Development Phase 3 Adv. Development Phase 4 Pre-Launch Launch

SDA Omega-3 Soybean Oil Confirms Heart Health Benefits SDA Omega-3 Soybean oil for food applications (bread, cereal bars, dairy drinks, spreads, dressings)

2 0 Control 12 Weeks Soy Oil Diet Presented at: American Heart Association Scientific Sessions Nov. 14, 2009 by Dr.

001 compared to soy oil control; SDA and EPA not different p=0.

11 SDA Omega-3 Soybean Oil Confirms Heart Health Benefits SDA Omega-3 Soybean oil for food applications (bread, cereal bars, dairy drinks, spreads, dressings) triglycerides) Discovery Phase 1 Proof of Concept %EPA IN RED BLOOD CELLS Control 12 Weeks Soy Oil Diet Presented at: American Heart Association Scientific Sessions Nov. 14, 2009 by Dr. William Harris Control * 12 Weeks EPA Oil Diet Control 12 Weeks * SDA Oil Diet *Per protocol population of 157 subjects; p<0.001 compared to soy oil control; SDA and EPA not different p=0.101 Phase 2 Early Development CLINICAL STUDY RESULTS SHOW CONVERSION TO HEART HEALTHY EPA Aquaculture and feed applications SDA diet more than doubles heart healthy EPA levels compared to commodity soy SDA diet exhibited a significant reduction in triglycerides (26-30% versus control for subjects with high baseline triglycerides within subjects with high baseline Phase 3 Adv. Development Phase 4 Pre-Launch Launch

5 SDA provides excellent flavor and shelf life in taste tests SDA works in a broad variety of foods

0 5.0 We have a strong interest in evaluating SDA in foods based on these impressive samples Food

12 SDA Omega 3 Hitting Food Application Targets SDA Omega 3 soybean oil flavor profile outperforms alternative sources of Omega-3 Total Off Flavor 12 months Granola Bars 7.5 SDA provides excellent flavor and shelf life in taste tests SDA works in a broad variety of foods from cereal bars to beverages and spreads Low Score Wins! We have a strong interest in evaluating SDA in foods based on these impressive samples Food Company Feedback Control Soy SDA Soy Flax Algal Fish Encapsulated Fish 0-15 Scale National Food Laboratory. Nut and Berry Granola Bar Sensory Results. July 2008.

Vistive Gold Soybeans Provide Low Saturated Fat, High Stability, Zero Trans Fat Oil for Food PRODUCT CONCEPT: Specified by Food Companies Improve consumer health (reduce trans & sat fat) Improve food

13 Vistive Gold Soybeans Provide Low Saturated Fat, High Stability, Zero Trans Fat Oil for Food PRODUCT CONCEPT: Specified by Food Companies Improve consumer health (reduce trans & sat fat) Improve food product performance (increase oxidative stability) Establish soybean oil as preferred domestic source (>20M acres potential) Key applications: High Stability Frying, Snack Foods and Baked Goods Soybean Oil - Fatty Acid Composition (%) 16:0 Palmitic 18:0 Stearic 18:1 Oleic 18:2 Linoleic 18:3 Linolenic Commodity Soybean Oil Benefits Reduce Saturates Increase Stability Reduce Trans Fat Discovery Phase 1 Proof of Concept Phase 2 Early Development Phase 3 Adv. Development Phase 4 Pre-Launch Launch

Vistive Gold Designed to Deliver Food Nutrition Benefits and

30 PERCENT Designed to provide food companies a cost-effective

products that provide improved functional performance.

Merlin Development and Monsanto 0.8% TFA + 13.4% SFA 0.3% TFA + 13.

14 Vistive Gold Designed to Deliver Food Nutrition Benefits and Establish Consumer Platform French Fry Study Phase 4 Pre-Launch 30 PERCENT Designed to provide food companies a cost-effective vegetable oil that enables them to create new and better food products that provide improved functional performance. Consumer health benefits High Oleic Lowers saturated fats Eliminates trans fat Trans Fat 15.7% % Sat Fat & Trans Fat in French Fries Sat Fat 23.4% % TFA % SFA 5 0 Partial Hydro Soy Oil Gen I Vistive Soy Oil Source: 2009 Merlin Development and Monsanto 0.8% TFA % SFA 0.3% TFA % SFA High Oleic Low Lin Canola Vistive Gold Soy Oil Reduced saturated fat 43 percent and trans fat 98 percent in French fries Enables Zero Trans Fat on nutrition facts and Clean Labels (no trans-fat, low saturated fat)

15 Questions? Thank you for your time!!

Monsanto s s Pipeline for Biotech Crops. Vice President, Consumer Traits Monsanto Company

Monsanto s s Pipeline for Biotech Crops David M Stark Ph D David M. Stark, Ph.D. Vice President, Consumer Traits Monsanto Company 2 3 850+ million hungry grain consumption has exceeded production 7/10