Real Hydrophilic Ceramide. Series
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1 Real Hydrophilic Ceramide Series
2 Table of content What is Ceramide? Main functions of Ceramide Advantage of Ceracare Series Summary of Ceracare Series Properties of Ceracare Series Clinical study of Ceracare H30EX Directions of using Ceracare Series Commercial products of Ceracare Series Guide formula of Ceracare Series
3 About Ceramide Ceramide - one of main components for skin lipids well-known for its excellent efficacy for cosmetics. However, it is very difficult to apply because of its low solubility both into water and oil and forming recrystallization Normal Skin Damaged Skin Horny Layer : CERAMIDE 2 : CHOLESTEROL 3 : FREE FATTY ACID 1. Change of lipid composition - Lower contents of Ceramide (Causing skin troubles) 1. Composition of skin lipids - CERAMIDE : 40% - CHOLESTEROL : 25% - FREE FATTY ACID : 25% * FREE SPHINGOIDS : (nmol/mg protein) - PHYTOSPHINGOSINE : SPHINGOSINE : SPHINGANINE : 0.5 ref.) J Chromato B Biomed Appl 1994, 656(1):65-71 Epidermis Dermis 2. Dry skin - Dry and rough skin - Reduced elasticity - Causing wrinkle and troubles 3. More people have skin troubles - Bed smell in skin - Acne - Atopic troubles
4 Main functions of Ceramide TEWL Recovering effect by dosages of Ceramide Ceramide Moisurizing Blank ceramide NP 1.0% Effective for Transepidermal water loss Recovering Moisturizing effect increase as the content of ceramide increase Can make high moisturizing product
5 Main functions of Ceramide Change in the composition of the lipid of Caucasians' stratum corneum caused by aging External supply is needed since ceramide decreases by aging Healthy skin barrier - Ceramide, the essential ingredients for healthy skin
6 Advantage of Ceracare Series Ceracare H40EX, 30S overcame the problems of low-solubility and recrystallization of original Ceramide, thus it is easy and stable to disperse into water. SEM (x1000) SEM (x1000) [ Ceracare H40EX DSC Data ] SEM (x7000) SEM (x7000) 97.7 Pure ceramidenp Ceracare H30EX [ A Regular Shape ] [ Amorphous ] We modified Ceramide NP to amorphous form to prevent recrystallization Sh ift The solubility have been better. Pure Ceramide NP Amorphous Ceracare Series (Water dispersible)
7 Advantage of Ceracare Series [Microphotograph of 2% of Ceracare H30EX into water ] [Microphotograph of 1% of Ceracare H40EX into emulsion] 1 day after (X400) 3 years after (X400) <Formula : P. Water To Keltrol F 0.1% + Butylene Glycol 5% + Ceracare H30EX 2% + Phenonip 0.6%> 1 day after (X400) 3 years after (X400) Ceracare H30EX Ceramide Emulsion Ceracare H30EX 1% applied Unique moisturizing skin feeling after absorption Outstanding soft texture from ceramide
8 Summary of Ceracare Series Ceracare H40EX Ceracare H30EX Cerecare H5 Cerasterol Vita-cerasterol Ceramide Water Appearance Yellowish powder Yellowish powder A little yellowish or brownish Gel Yellowish powder Translucent Viscous Liquid A little milky opaque Liquid Ceramide NP Content 40±2% 30±1.5% 5± 0.2% 10±1% 1±0.2% 0.2 ± 0.05% Cholesterol Content % 0.5% 0.1% Sphingolipid Content % - 0.2% Tocopheryl acetate Content % - Benefit Luxurious feeling Suitable for Emulsion product Luxurious feeling Suitable for all products Suitable for Emulsion product Easy to use (Can add at the end) Ceramide NP, Sphingolipid, Cholesterol Similar with skin lipid Mixed with Tocopheryl acetate Vitamin concepr Substitute for purified water Low price Picture Recommend Emulsion Toner, Emulsion Emulsion, Hair care Toner, Emulsion All products All products Hydration Step Required Required None Required None None
9 Properties of Ceracare Series Origin of Ceramide Natural Yeast Fermentation The natural Ceramide same with human Ceramide It uses structurally the same natural ceramide with one in human skin. (Does not use Pseudo-Ceramide..) Ceramide Yeast Strain Pre-Ceramide Long-Lasting Moisturizing Effect Technical Benefits Water-dispersible Ceramide High skin-familiar structure High purity of Ceramide Application Benefits Instant Skin Texture Improving effect Increase softness and gloss of skin instantly Excellent for improving dry and aged skin
10 Corneometer (A.U.) Clinical study of Ceracare H30EX Clinical Data Before App.After App Clinical Center : The Clinical Trial Center for Bio-Industry at Semyung University Total Volunteer : 22 persons Hours Not Applied Normal Serum (Blank) 2% of H30S + Normal Serum (Contained 2% of H30S) It shows a differentiated long-lasting moisturizing effect compare with other moisturizing agents. Patch Test Clinical Center : The Clinical Trial Center for Bio-Industry at Semyung University Total Volunteer : 30 persons Analysis method: Checking is proceeded 30 mins, 24 hours and 48 hours after removing patch. Skin response was sorted by the standard of International Contact Dermatitis Research Group(ICDRG). Average skin response(mean Score) was estimated by the official formulation and determined by Patch Test standard table. Test result: There was no irritation 30 mins, 24 hours and 48 hours after removing the patch. Average skin response score was 0.00, so it determined as no-irritation. Mean Score 0.00 Decision No irritation
11 Directions of using Ceracare Series ( Direction 1 ) Applying into Oil-phase 1) Put Ceracare (H40EX, H30EX or Cerasterol) into oil phase (with other oil ingredients and emulsifiers) Ceracare H40EX, H30EX Homogenizer Heating 2) Heat it to about 75 while mixing for 10~15 mins(h/m 5000rpm). 3) And then, process the other steps of emulsifying and finish. Oil Phase Hot Plate The benefits of Direction 1 1. Very simple way to apply. H40EX H30EX Cerasterol ( Direction 2 ) Dissolving in Polyol Ceracare H40EX, H30EX Homogenizer Heating 1) Put Ceracare H30EX(or H40EX, Cerasterol) into Polyol(Dipropylene glycol, 1,3-Butylene glycol, Propylene glycol, Glycerin) and heat to 70~80 to solve them transparently. Polyol 2) Put the above 1) polyol base into the water heated to 70~80 and agitate it for 5 mins (H/M 5000rpm). Hot Plate 3) After checking whether the hydration be done well, add other ingredients into the water phase to solute or emulsify or just cool down it. The benefits of Polyol dissolving 1. Getting better skin-feel 2. Quickly dispersed into water Other Water or Oil Phase
12 Guide Formula_ [Ceramide Premium Cheese Cream] Phase Trade Name Con.(%) INCI Name Maker Purified Water Purified Water - A Ceracare H40EX 1.00 Ceramide NP, Hydrogenated Lecithin, PEG-10 Rapeseed Sterol, Glyceryl S tearate, Glycereth-20, Dipropylene Glycol Picocare SE 2.00 Hydrogenated Lecithin, Myristic Acid, Stearic Acid, Behenic Acid, Stearyl Alcohol, Behenyl Alcohol 60 Heating. Hydration, H/M 2000rpm, 20 min. B Kelterol-F 0.10 Xanthan Gum CP Kelco Glycerin 5.00 Glycerin KAO Turmericgel 1.00 Lactobacillus Ferment, Curcuma Longa (Turmeric) Root Extract, Bu tylene Glycol, 1.2-Hexanediol NF-Fucoidangel 2.00 Biosaccharide Gum-1, 1,2-Hexanediol 1,3-B.G Butylene Glycol KAO 80 Heating. Mixing, H/M 3000rpm, Paddle 25rpm, 10 min. C Stearic Acid 1.00 Stearic Acid Emery Lanette O 1.00 Cetearyl Alcohol BASF Simulsol Glyceryl Stearate, PEG-100 Stearate Seppic Montanov Arachidyl Alcohol, Behenyl Alcohol, Arachidyl Glucoside Seppic NF-Ester EHS 5.00 Ethylhexyl Stearate NF-HPIB Hydrogenated Polyisobutene Aqua Solution Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Lauryl PEG-9 Polydi methylsiloxy ethyl Dimethicone, Dimethicone/Vinyl Dimethicone Crosspol ymer, Cyclopentasiloxane NF-Silkysome TF 2.00 Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer Cosmol Diisostearyl Malate Nissin OilliO Vaseline 3.00 Petrolatum Merku Vitamin E Acetate 0.50 Tocopheryl Acetate BASF D Simulgel NS 1.00 Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolyme r, Squalane, Polysorbate 60 Seppic E Hydrolite 6 O ,2-Hexanediol Symrise 80 Heating. 25 Emulsifying, H/M 3500rpm, Paddle 25rpm, 10 min. Mixing, H/M 3000rpm, 5 min. 45, Mixing, H/M 3000rpm, 5 min. Vacuuming, Cooling, Paddle 15rpm. Filtering and Finish
13 Guide Formula_ [Ceramide Whitening Eye Cream] Phase Trade Name Con.(%) INCI Name Maker Purified Water Purified Water - Ceramide NP, Hydrogenated Lecithin, PEG-10 Rapeseed Sterol, Gly Ceracare H40EX 1.00 A ceryl Stearate, Glycereth-20, Dipropylene Glycol Picocare SE 3.00 Hydrogenated Lecithin, Myristic Acid, Stearic Acid, Behenic Acid, Stearyl Alcohol, Behenyl Alcohol 60 Heating. Hydration, H/M 2000rpm, 20 min. B Kelterol-F 0.20 Xanthan Gum CP Kelco Glycerin 5.00 Glycerin KAO Niacinamide PC 2.00 Niacinamide DSM Turmericgel 1.00 Lactobacillus Ferment, Curcuma Longa (Turmeric) Root Extract, But ylene Glycol, 1.2-Hexanediol NF-Fucoidangel 2.00 Biosaccharide Gum-1, 1,2-Hexanediol 1,3-B.G Butylene Glycol KAO 80 Heating. Mixing, H/M 3000rpm, Paddle 25rpm, 10 min. C Stearic Acid 1.00 Stearic Acid Emery Lanette O 2.00 Cetearyl Alcohol BASF Simulsol Glyceryl Stearate, PEG-100 Stearate Seppic Montanov Arachidyl Alcohol, Behenyl Alcohol, Arachidyl Glucoside Seppic NF-Ester EHS 6.00 Ethylhexyl Stearate NF-HPIB Hydrogenated Polyisobutene Aqua Solution Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Lauryl PEG-9 Polydimethylsiloxy ethyl Dimethicone, Dimethicone/Vinyl Dimethico ne Crosspolymer, Cyclopentasiloxane NF-Silkysome TF 3.00 Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer Vitamin E Acetat e 0.50 Tocopheryl Acetate BASF D Simulgel NS 0.50 E Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Polysorbate 60 Seppic NF-Velvet 1.50 Adipic Acid/Neopentyl Glycol Crosspolymer, Water, Aminodimethic one, Dimethicone, Hydroxypropyl Methylcellulose, VP/VA Copolym er. Hydrolite 6 O ,2-Hexanediol Symrise 80 Heating. 25 Emulsifying, H/M 3500rpm, Paddle 25rpm, 10 min. Mixing, H/M 3000rpm, 5 min. 45, Mixing, H/M 3000rpm, 5 min. Vacuuming, Cooling, Paddle 15rpm. Filtering and Finish
14 Guide Formula_ [Ceramide Fluid Essence] Phase Trade Name Con.(%) INCI Name Maker Purified Water Purified Water - 60 Heating. Ceracare H30EX 1.00 Ceramide NP, Hydrogenated Lecithin, PEG-10 Rapeseed Sterol, Glyceryl Streate, Glycereth- 20, Dipropylene Glycol A 1,3-B.G Butlyene Glycol KAO Keltrol F 0.10 Xanthan Gum CP Kelco NF-Fucoidangel 2.00 Biosaccharide Gum-1, 1,2-Hexanediol Mixing, H/M 3000rpm, Paddle 25rpm, 20 min. Turmericgel 1.00 Lactobacillus Ferment, Curcuma Longa (Turmeric) Ro ot Extract, Butylene Glycol, 1.2-Hexanediol B NF-Ellasome E Dimethicone/Vinyl Dimethicone Crosspolymer, Cyclop entasiloxane, Hydrogenated Lecithin, 1,2-Hexanediol, Water 45 Mixing, H/M 2500rpm, 5 min. C Hydrolite 6 O ,2-Hexanediol Symrise 25 Mixing, H/M 2500rpm, 5 min. Vacuuming, Cooling, Paddle 15rpm. Filtering and Finish
15 Commercial products of Ceracare Series (Skin-care) The history of Whoo : Hwahyun Cream The history of Whoo : All-in-one Cream The history of Whoo :Jinyul Essence Su:m 37 : Secret Programming Essence Manufacturer : LG H&H Package : 80 ml ($80) Launched in 2009 The history of Whoo : Qi&Jin Eye Cream Manufacturer : LG H&H Package : 20 ml ($60) Launched in 2011 ISAKNOX: Original recovery Skin & Lotion ISA KNOX X2D2 Ceramide 100 cream SUM 37: Secret Programing Eye Cream SUM 37: Time energy Skim Resetting Softening Emulsion The history of Whoo : Hwahyun Lotion
16 Commercial products of Ceracare Series (Skin-care) Whoo : Hwanyu Cream ISAKNOX: Original Hydra Skin & Lotion Re:NK Extra moisture - Hydra Queen Cream SUM 37: Losec Therapy Ampoule Danahan Anti-Wrinkle Essence, Cream, Lotion, Eyecream ISAKNOX: NOXLAB Skin & Lotion Sum 37 Sum 37 Sum 37 Secret for man programing Essence Flawless regenerating Eye-Cream Skin resetting repairing Serum SUM 37: Losec Therapy Ampoule Whoo: Qi&Jin Essence Sum 37 Flawless regenerating Skin
17 Commercial products of Ceracare Series (Make-up, Sun) Whoo Jinhaeyoon Sun Cream (SPF50+/PA+++) Belif Almighty Sun Powder (SPF50+/PA+++) The Saga of Soo Sunhyeyun Jadan Sun Cream (SPF50+/PA+++) Sum37 Sweet Smile Mild Sun Cushion (SPF32/PA++) 诗佳秀善蕙润紫断防晒霜 Beyond Timeless Cell Renew BB (SPF28/PA++) Belif Moisture Balm Cushion VDL Expert Color Lip Cube EX SPF10 TheFaceShop Collagen Ampoule Lipstick
18 Main Office : 인천연수구갯벌로 145번길 15-8 (15-8 Gaetbeol-ro 145beon-gil, Yeonsu-gu, Incheon City) Contact Number : Tel (82) / Fax (82) Contact Person : 영업부송재근과장 (Eric from Sales Department) eric.song@nfccos.com Homepage :
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