DEPARTMENT OF VIROLOGY

Transcription

1 DEPARTMENT OF VIROLOGY NELSON R MANDELA SCHOOL OF MEDICINE, UNIVERSITY OF KWAZULU-NATAL, and INKOSI ALBERT LUTHULI CENTRAL HOSPITAL, KZN BRANCH, NATIONAL HEALTH LABORATORY SERVICE Biomedscience III Virology (MVI311) (16 Credits) 2011 Venue: Westville Campus Department of Virology Secretary Contact Details: Mrs. Vaneshree Murugan Tel muruganv@ukzn.ac.za Department of Virology Course Co-ordinator Contact Details: Ms. Anneta Naidoo naidooa5@ukzn.ac.za Biomedscience Class Representative: Ngcoya Sibonelo BSc Med. Course Handout 2011 Page 1 of 7

2 Contents Page 3-4 Page 4 Page 5-7 Page 7 Time Table Written Assignments (WA) Lectures (LEC) Assessment BSc Med. Course Handout 2011 Page 2 of 7

3 Time Table DAY TIME PERIOD (M) Mondays (W) Wednesdays (T) Thursdays (F) Fridays 10h30-12h10 4, 5 13h15-14h00 7 8h40 9h h10-15h Table 1 : Timetable 2011 Date Time Topic Venue M 7 February h30-12h10 Introduction and Orientation AFN W 9 February h15-14h00 Viral Classification and Structure LS T 10 February h40 9h25 Viral Replication AFN F 11 February h10-15h50 Pathogenesis LS M 14 February h30-12h10 Viral Genetics and Evolution W 16 February h15-14h00 Self-Study T 17 February h40 9h25 Self-Study F 18 February h10-15h50 Immunology FC M 21 February h30-12h10 Oncogenesis NT W 23 February h15-14h00 Oncogenesis NT T 24 February h40 9h25 Self-Study F 25 February h10-15h50 Epidemiology AFN M 28 February h30-12h10 Apoptosis FC W 2 March h15-14h00 Genetherapy LS T 3 March h40 9h25 Self-Study F 4 March h10-15h50 Polio NT M 7 March h30-12h10 HIV FC W 9 March h15-14h00 Hepatitis B NT T 10 March h40 9h25 Self-Study F 11 March h10-15h50 TEST 1 M 14 March h30-12h10 Herpesviruses NT W 16 March h15-14h00 Hepatitis C FC T 17 March h40 9h25 Self-Study F 18 March 2011 Public Holiday M 21 March 2011 Public Holiday W 23 March h15-14h00 Influenza NT T 24 March h40 9h25 Self-Study F 25 March h10-15h50 Tutorial test and assignment 1 M 28 March h15-16h35 Emerging viruses FC W 30 March h15-14h00 Antivirals NT T 31 March h40 9h25 Self-Study F 1 April h10-15h50 Vaccines FC M 4 April h10-15h50 Laboratory Validity LS BSc Med. Course Handout 2011 Page 3 of 7

4 W 6 April h15-14h00 PCR AFN WA AFDUE T 7 April h30-12h10 Self-Study F 8 April h10-15h50 Hybridisation AFN M 11 April h30-12h10 Cloning AFN W 13 April h15-14h00 Laboratory Diagnosis AFN T 14 April h40 9h25 Self-Study F 15 April h10-15h50 Visit to laboratory AFN/LS M 18 April h30-12h10 Test 2 W 20 April h10-15h50 Sequencing AFN F 21 April 2 May 2011 HOLIDAY WEEK W 4 May h15-14h00 Drug Resistance LS T 5 May h40 9h25 Self-Study F 6 May h10-15h50 Viral loads AFN M 9 May h30-12h10 Bioinformatics LS W 11 May h15-14h00 Nanotechnology AFN T 12 May h40 9h25 Feedback on Test 2 F 13 May h10-15h50 Revision M 16 May h30-12h10 Revision W 18 May h15-14h00 Revision T 19 May h40 9h25 Revision F 20 May h10-15h50 Revision WRITTEN ASSIGNMENTS (WA) Please note the following regarding these sessions: WA: Emerging and re-emerging viral infections present a great challenge to modern medicine. The SARS outbreak in 2003, the re-emergence of Influenza annually and the ever changing HIV all have impacted on clinical and laboratory medicine greatly. Discuss emerging and re-emerging viral infections as follows: 1. Concept of Emerging and re-emerging viral infections 2. Viral and Host factors which influence these Emerging and re-emerging viral infections. 3. An approach to identifying suspected new viral pathogens. 4. Laboratory techniques which are used in identifying suspected new viral pathogens. 5. Current Emerging and re-emerging viral infections DUE DATE: WA: 6 April 2011 BSc Med. Course Handout 2011 Page 4 of 7

5 Assignment preparation must begin from the first day of lectures. Plagiarism of previous students work will not be tolerated and NO marks will be granted for such work. Definitely NO cutting and pasting from the internet. Each assignment must be 5 A4 pages. The Title, Student name and number must appear at the top of your work. Do not include a cover page. The format of the work -Font type- Times New Roman NOT bold type -Font Size- 12 -Line spacing Single sided print only The content of the work -An insightful discussion of the topic must be evident. -Appropriate headings and sub-headings are essential. -Diagrams and tables may be used cautiously and sparingly. -A minimum of 5 references must be consulted - of these only one is to be a university website, the others must be appropriate reference books and journals. The assignments will contribute 5% to the course assessment. All assignments must be handed to the lecturer on the due date. He/she will acknowledge receipt using the class register. Unless prior arrangements are facilitated and agreed to, delays will be penalized.( 2.5% will be deducted for each day of delay) LECTURE SESSIONS (LEC) Please note the following regarding these sessions: Appropriate attendance will facilitate accumulation of adequate knowledge and understanding to facilitate passing the final examinations Students are expected to take good notes during the lecture. Notes will only be made available when essential. The lectures are to facilitate your reading to supplement your knowledge. Reading before the lecture will obviously enhance learning during the lecture. BSc Med. Course Handout 2011 Page 5 of 7

6 LECTURE Topics and references 1. Viral Taxonomy Fields Virology 5 th edition. Volume I, Chapter 2, pgs Viral Structure Fields Virology 5 th edition. Volume I, Chapter 3 3. Replication Fields Virology 5 th edition. Volume I, Chapter 5 4. Viral Genetics and Viral Evolution Medical Virology. Fenner and White (4 th eds). Chapter 4 5. Pathogenesis Fields Virology 5 th edition. Volume I, Chapter Immunology Fields Virology 5 th edition. Volume I, Chapter 9 Fields Virology 5 th edition. Volume I, Chapter Oncogenesis Viral Pathogenesis. Nathanson (ed). Chapters 10 and Epidemiology Fields Virology 5 th edition. Volume I, Chapter Viral Vaccines Fields Virology 5 th edition. Volume I, Chapter Antivirals Fields Virology 5 th edition. Volume I, Chapter 14 Essentials of Diagnostic Virology. Storch (ed). Chapter Genetherapy Fields Virology 5 th edition. Volume I, Chapter 16 Clinical Virology 2 nd edition. Richman (ed). Chapter 15. Fields Virology 4 th edition. Fields (ed). Chapter Apoptosis Thomson BJ. Viruses and Apoptosis. (2001) International Journal of Experimental Pathology. April 82(2): Emerging Viruses Fields Virology 5 th edition. Volume I, Chapter Prions Fields Virology 5 th edition. Volume II, Chapter Hepatitis C Virus Fields Virology 5 th edition. Volume I, Chapter Hepatitis B Virus BSc Med. Course Handout 2011 Page 6 of 7

7 Fields Virology 5 th edition. Volume II, Chapter Polio Fields Virology 5 th edition. Volume I, Chapter Influenza virus Fields Virology 5 th edition. Volume I, Chapter Herpesviruses Fields Virology 5 th edition. Volume II, Chapter Human Immunodeficiency Virus Fields Virology 5 th edition. Volume II, Chapter 57 Location of References Westville Campus Main Library Librarian: Pravina Lalljeeth Health Sciences Level Pure Sciences Level ASSESSMENT TESTS: Test 1 date: 11 March 2011 Test 2 date: 18 April 2011 Venue to be announced. The mark allocation will be as follows: CLASS TEST=2 X 15% = 30% WA=1 X 10%= 10% FINAL EXAMINATION = 60% BSc Med. Course Handout 2011 Page 7 of 7