National Clinical Conference 2018 Baltimore, MD
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1 National Clinical Conference 2018 Baltimore, MD
2 No relevant financial relationships to disclose
3
4 Wound Care Referral The patient has been maximized from a vascular standpoint. She has no other options. Can you see what you can do?
5 Wound Care Strategy Basic Wound Care Wound Assessment and Classification
6 Foot Ulcer Etiology Arterial Venous Neuropathic Pressure Surgical Atypical Wound Care Specialist Management
7 Wound Care Strategy Basic Wound Care Wound Assessment and Classification Optimization of Disease Management Debridement Off Loading Compression Therapy Moist Wound Healing Infection Management Vascular Evaluation Advanced Wound Care
8 The Wound Care Center Unique Knowledge & Training Wound Care Specialist Evidence Based Algorithms & Protocols Specialized Technology HBOT Cellular and/or Tissue Based Products NPWT HIGH INDEX of Suspicion for Vascular Disease
9 Atherosclerosis Affects up to 10% of the Western population older than 65 years Expected to increase 22% by the year 2040 Population > 65 years Expected to have a huge financial impact on medicine. Using claudication is used as an indicator 2% of the population aged years 6% of the population older than 70 years
10 Ischemic Ulcers
11 Prevalence of PAD PAD prevalence rates by noninvasive testing: 2.5% at ages 40 to 59 years 8.3% at ages 60 to 69 years 18.8% at ages 70 to 79 years Prevalence has been shown to be higher in men than in women Critical Limb Ischemia 1% > 70 years Criqui MH, Denenberg JD, Langer RD, Fronek A. The epidemiology of peripheral arterial disease: importance of population at risk. Vasc Med 1997;2:221-6 Criqui MH, Denenberg JO, Langer RD, Fronek A. The epidemiology of peripheral arterial disease: importance of identifying the population at risk. Vasc Med 1997;2:221-6 Murabito JM, D'Agostino RB, Silbershatz H, Wilson WF. Intermittent claudication. A risk profile from The Framingham Heart Study. Circulation 1997;96:44-9.
12 PAD Associated Mortality Norgren L, Hiatt WR, Dormandy JA, TASC II Working Group et al (2007). "Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)". J Vasc Surg. 45 (Suppl S): S5 67
13 Death Rates By Disease The likelihood of a diabetic being dead five years after a amputation is nearly 50%. This is more than double the chance of death from prostate or breast cancer. Brem H, et al; Protocol for treatment of Diabetic Foot ulcers Am J Surg S pp 1-10
14 PAD Comorbid Conditions Cerebrovascular Disease CVD is present in 50-75% of PAD patients, 5% overlap between PAD, CAD, and CVD in men and women aged 62 years and older. Intermittent Claudication and Mortality Rate 5 year mortality 30% 10 year Mortality 50% 15 year mortality rates 70% Cardiovascular cause estimated to be responsible for 70% to 80% of deaths Criqui MH, Denenberg JO, Langer RD, Fronek A. The epidemiology of peripheral arterial disease: importance of identifying the population at risk. Vasc Med 1997;2:221-6 Management of peripheral arterial disease (PAD). TransAtlantic Inter-Society Consensus (TASC) Working Group. J Vasc Surg 2000;31(1 Pt.2):S5-S14, S93-S101 Ogren M, Hedblad B, Isacsson SO, Janzon L, Jungquist G, Lindell SE. Non-invasively detected carotid stenosis and ischaemic heart disease in men with leg arteriosclerosis. Lancet 1993;342:
15 Clinical Presentation Chronic Arterial Insufficiency Accompanying Physical Signs Absent Pulses Pallor Dependent Rubor Coolness Absent Hair Dry Skin Odor of Tobacco Prior Amputations
16 Ulcer Characteristics Location Typically distal Appearance +/- necrosis +/- dry Typically shallow Pain Typically painful
17 Vascular Evaluation Wound Care Clinic Physical Examination
18 Vascular Assessment: Pulses
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20 Palpable Pulses! In patients with PAD (as detected by ABI) 74% had a palpable pulse More than two thirds of the patients within the study group with evidence PAD had a palpable pulse The sensitivity of a non-palpable pulse for the diagnosis of PAD was 26% Pulse palpation is not sensitive for the detection of PAD when compared to ABI
21 Vascular Evaluation Wound Care Clinic Physical Examination Ankle/brachial index (ABI) Toe Brachial Index (TBI) Transcutaneous oxygen tension (TCOM) Skin Perfusion Pressure (SPP)
22 Vascular Assessment: ABI Ankle-Brachial Index Index = Highest of DP or PT pressures Highest of R or L Brachial Pressures Calculated For Each Leg Separately
23 Vascular Assessment: ABI Ankle-Brachial Index < 0.9 suggests atherosclerotic vascular disease with 95% sensitivity and 99% specificity Falsely elevated when arteries heavily calcified as is seen in diabetes Baumgartner I, Schainfeld R, Graziani L. Management of peripheral vascular disease. Annu Rev Med. 2005;56: Guo X, Li J, Pang W, Zhao M, Luo Y, Sun Y: Sensitivity and specificity of ankle-brachial index for detecting angiographic stenosis of peripheral arteries. Circ J 2008, 72:
24 Vascular Assessment: TCOM
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26 TCOM Clinical Guidelines TCOM > 40 mmhg in Diabetic Patient predicts likelihood of healing TCOM > 30 mmhg in Non-Diabetic Patient predicts likelihood of healing Identifies islands of ischemia in extremity TCOM can be used to measure response to oxygen during hyperbaric therapy
27 SPP Clinical Guidelines Skin Perfusion Pressure A distal arterial perfusion test Utilizes laser Doppler to evaluate reactive hyperemia Measures in millimeters of mercury (mmhg) the pressure at which blood flow first returns to capillaries following controlled release of occlusion SPP value is highly effective in detecting PAD, predicting healing potential and disease severity.
28 SPP Clinical Guidelines Sensilase Capillary occlusion Diamond marks: Return of blood flow SPP value Controlled cuff release
29 SPP Clinical Guidelines
30 Vascular Assessment Vascular Center - Referral Duplex Ultrasonography Advanced Imaging CTA / MRA Contrast Angiography
31 Second Opinion CRITICAL The patient has been maximized from a vascular standpoint. TRANSLATION The patient has been maximized based on my technical expertise
32 Case Study 63 year old male PMH of CAD, IDDM Right plantar foot ulcer 2 months duration Presented to ED with cellulitis and distal foot ischemia Admitted IV ABX Surgical debridement Open TMA TCOM Evaluation
33 2-18
34 2-18
35 3-19
36 5-3
37 5-3
38 5-24
39 6-12
40 6-26
41 7-24
42 12-3
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44 CASE STUDY 90 year old female DM, PAD Right Malleolar DFU with Osteo Multiple vascular surgical interventions No other options Scheduled for BKA Second Opinion No distal pulses TCOM evaluation at BKA level ALL less than 15mmHg ENDO-Revascularization Copyright 2017 KCI Licensing, Inc. and Systagenix Wound Management, Limited. All rights reserved. ME2018.#046.AWD
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49 CASE STUDY Wound Management Topical Regimen HBOT Copyright 2017 KCI Licensing, Inc. and Systagenix Wound Management, Limited. All rights reserved. ME2018.#046.AWD
50 02/20/2018
51 03/2/2018
52 03/7/2018
53 Thank You.
54 National Clinical Conference 2018 Baltimore, MD
USWR 23: Outcome Measure: Non Invasive Arterial Assessment of patients with lower extremity wounds or ulcers for determination of healing potential
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UC SF. Disclosures. Vascular Assessment of the Diabetic Foot. What are the best predictors of wound healing? None. Non-Invasive Vascular Studies
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Will it heal? How to assess the probability of wound healing
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