As adopted by HMPC 2006

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1 The role of -monographs in university research and teaching Liselotte Krenn 20 Years of ESCOP Cologne,

2 History of -Monographs 1989 ESCOP Scientific Committee starts work on the monographs 1992 first publication of monographs and submission to the CPMP 1996/1997/1999 publication of 60 monographs

3 History of -Monograph Monographs 2003 Second edition completely revised and expanded 2009 Supplement with 28 new monographs + 7 revised monographs

4 Elaboration of -Monographs Draft of expert or project leader Check by Sci. Comm. members Discussion in the Meeting Revision Final editing Board of Supervisors Approval in Sci. Comm.

5 As adopted by HMPC 2006

6 Citations of -Monographs based on a search in Scopus

7 Citations of -Monographs IRELAND

8 Advantages of - Monographs in Scientific Use balanced evaluation of literature due to the composition of the Sci. Comm. comprehensive compilations of relevant pharmacological, toxicological and clinical studies complete list of references up to 200 per monograph Publication of revisions!

9 Clinical studies since Drug monitoring studies Open studies Comparative studies Placebo-controlled studies Pharm. studies in humans Ginkgo Hypericum Cimicifuga Garlic Harpagophytum based on ESCOP-Monographs and Medline

10 Scientific Use of -Monographs for calculations of dosages in animal studies

12 Scientific Use of -Monographs for calculations of dosages in clinical studies

13 Scientific Use of -Monographs as a basis for reviews

14 Scientific Use of -Monographs to substanciate indications

15 Use of -Monographs in Teaching in the developement of courses in phytotherapy as a basis for examinations on respective plants as a basis in discussions ions of the feasibility of different assays, their advantages and limitations

16 New monographs in the Supplement Agrimoniae herba Ph.Eur. Aloe barbadensis Ph.Eur. Angelicae radix Ph.Eur. Ballotae nigrae herba Ph. Eur. Boswellia serrata (Olibanum) Capsici fructus Ph. Eur. Cardui mariae fructus Centellae asiaticae herba Ph.Eur. Crataegi fructus Ph. Eur. Cucurbitae semen Curcumae xanth. rhizoma Ph.Eur. Echinaceae angust. radix Ph.Eur Eur. Fumariae officinalis herba Graminis rhizoma Ph.Eur Eur. Grindeliae herba Lavandulae flos Ph.Eur. Malvae sylvestris flos Ph.Eur. Melaleucae aetheroleum Ph.Eur. Millefolii herba Ph.Eur. Paullinia cupana (Guaraná) Pruni africanae cortex Ph. Eur. Ratanhiae radix Ph.Eur. Rosae pseudo-fructus Ph.Eur. Symphyti radix for topical use Vaccinium macrocarpon (Cranberry) Violae herba cum flore Ph. Eur. Vitis viniferae folium

17 Samples of new monographs in the Supplement

18 Revisions in the Supplement Cynarae folium Echinacea pallidae radix Ph. Eur. Echinacea purp. radix Ph. Eur. Echinacea purp. herba Eleutherococci radix Ph. Eur. Harpagophyti radix Ph. Eur. Valerianae radix Ph. Eur. Zingiberis rhizoma Ph. Eur.

19 ESCOP Supplement 2009 IN PRESS and AVAILABLE SOON

20 New monographs under preparation

21 Many Thanks to the Supervising Editors Prof. Robert Anton Dr. Desmond Corrigan Prof. Pierre Delaveau Prof. Dr. Gerhard Franz Prof. Dr. Catherine Harvala Prof. Dr. Fritz H. Kemper Prof. Dr. med. Karin Kraft Prof. Wolfgang Kubelka Prof. Dr. Dr. Dieter Loew Prof. Evelyne Ollivier Prof. Dr. R. Saller Prof. Dr. Heinz Schilcher Prof. Dr. Thomas Simmet Prof. Dr. Otto Sticher Prof. Franco F. Vincieri Prof. Dr. Arnold Vlietinck

22 Many Thanks to the Members of the Sci. Comm. Anna Rita Bilia I Peter R. Bradley GB Jan G. Bruhn S Jozef G. Corthout B Ingunn Egeberg N Marijke Frater-Schröder CH Nicola Fuzzati I Lene Gudiksen DK Didier Guédon F Stephen Hicks GB Ingrid Hook IRL Stephan F.A.J. Horsten NL Frédérique Lafforgue Norbert Linnenbrink Maria Carmen Recio Georg Seidel Ekrem Sezik Barbara Steinhoff Sonja Sturm F. M. van den Dungen Eckhart Wildi Martin Willoughby Jens K. Wold F CH E D TR D A NL CH GB N

23 Thank you for your attention!

New developments from the European Scientific Cooperative on Phytotherapy (ESCOP)

5th World Congress on Medicinal and Aromatic Plants WOCMAP 2014 Brisbane (Australia), 17-20 August 2014 New developments from the European Scientific Cooperative on Phytotherapy (ESCOP) Cañigueral, S 1,2,