THURSDAY 26 TH APRIL 2018 SCHEDULE PAGE 1 15 TH ANNUAL CRITICAL CARE SYMPOSIUM KING S HOUSE CONFERENCE CENTRE, MANCHESTER

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1 THURSDAY 26 TH APRIL 2018 SCHEDULE PAGE Registration Introduction KEYNOTE ADDRESS Non-antibiotic solutions for pan-resistant microbial pathogens Prof Steven Opal SEPSIS 1 FLUIDS Prof Paul Dark & Prof Fang Gao Smith & Prof Michel Slama New sepsis guidelines, facts and controversies Practical implication on a national scale Dr Ron Daniels Host pathogen interactions Sepsis biomarkers - where do we stand? Questions What is the ideal fluid in Critical Care? Fluid resuscitation - when to stop fluid administration Prof Jan De Waele Albumin in sepsis Prof Yasser Sakr Questions Coffee Break Coffee Break TOPICS 1 SEPSIS - MANIFESTATIONS, DIAGNOSIS & MONITORING & & Dr Ron Daniels Lessons learnt from emergency healthcare responses to the Manchester Arena bombing Prof Paul Dark Risk stratification and management of the high risk surgical patient The carmal total artificial heart: where are we up to? Prof Bernard Cholley Hospital readmissions in ICU survivors Dr Nazir Lone Questions Fever - friend or foe? Prof Steven Opal Maternal sepsis Prof Fang Gao Smith Septic shock and ARDS Holistic Critical Care ultrasound - can rapidly document a source of sepsis Prof Daniel Lichtenstein Acid-base - Stewart s approach How not to run an incident investigation in your unit

2 THURSDAY 26 TH APRIL 2018 SCHEDULE PAGE 2 PRO-CON DEBATE Chairperson: Dr Andrew Bentley An ICU follow-up clinic is too late for survivors PRO Prof Tim Walsh CON Dr Peter Spronk Questions Lunch SEPSIS - MANIFESTATIONS, DIAGNOSIS & MONITORING (continued) & Dr Ron Daniels How should you choose haemodynamic monitoring in septic shock patients? Prof Jean-Louis Teboul Questions Lunch ARDS SEPSIS - MANAGEMENT 1 Prof Tim Walsh & & Fluid management in ARDS Prof Jean-Louis Teboul Human models to define new treatments for ARDS Use of stem cells in ARDS Prof Geoff Bellingan Future therapies in ARDS Questions Coffee Break Source control in septic shock Prof Jan De Waele Septic shock: is the endotoxin removal an option? Prof Massimo Antonelli Volume optimisation in sepsis: understanding the evidence Prof Yasser Sakr Practical use of vasopressors in septic shock Prof Jean-Louis Teboul Questions Coffee Break Safety in ICU Tricks in ICU REHABILITATION See next page SEPSIS - MANAGEMENT 2 See next page

3 THURSDAY 26 TH APRIL 2018 SCHEDULE PAGE 3 REHABILITATION SEPSIS - MANAGEMENT 2 Dr Nazir Lone & Dr Deepak Govil Prof Steven Opal & Dr Miguel Tavares What quality indicators should we use for ICU rehabilitation? Prof Tim Walsh Engaging the patient in rehabilitation - interactive gaming is the future Dr Peter Spronk Animal assisted activity in ICU Evidence for physical rehabilitation across the recovery continuum and the evidence reality gap Dr Bronwen Connolly Rehabilitation post-icu - the REVIVE trial Questions Alkaline phosphatase for sepsis induced AKI EGDT in sepsis for Sepsis bundles in a resource limited country Questions EDUCATION Associate Prof Aarti Sarwal & POCUS in Intensive Care Dr Jonathan Wilkinson Stimulation for education in ICU: new scopes and scenarios Associate Prof Aarti Sarwal Social media - from tweets to bedside Questions Anaemia and blood transfusion issues - update Prof Tim Walsh Prof Yasser Sakr Practice of the RRT in ICU - the questions you are reluctant to ask for SYMPOSIUM DINNER Admission by pre-booked ticket only SYMPOSIUM DINNER Venue: Directors Suite The Principal Manchester Oxford Street Manchester M60 7HA AFTER DINNER SPEECH Have we got sepsis wrong?

4 FRIDAY 27 TH APRIL 2018 SCHEDULE PAGE Registration KEYNOTE ADDRESS Chairperson: years of ARDS: what has been changed? Prof Massimo Antonelli NUTRITION Dr Bronwen Connolly & Dr Ravi Kumar What, when and how? A standard bag of TPN vs custom made ones - what is the point? Future direction of nutritional research Dr Zudin Puthucheary Questions Coffee Break PRO-CON DEBATE Chairperson: Can expenses in ICU be brought under control? ECMO, blood purification, stem cell and LVADs etc. for ALL PRO CON Questions ARDS 2 Prof Xavier Monnet & Prof Geoff Bellingan First line intervention in hypoxemic patients: HFOT or NV Prof Massimo Antonelli Ultrasound to assess the diaphragmatic function in ventilated and critically ill patients Prof Bernard Cholley ECCO2R in acute respiratory failure Latest update on interferon in ARDS Prof Geoff Bellingan Questions Coffee Break WEANING Prof Xavier Monnet & Dr Andrew Bentley NAVA - when, how and to whom? Dr Deepak Govil Weaning failure due to cardiac origin Prof Xavier Monnet Telemedicine Ultrasound of diaphragm during mechanical ventilation Associate Prof Aarti Sarwal & Haemodynamic monitoring Prof Bernard Cholley & Antibiotics - all you need to know in Intensive Care Prof Paul Dark & Prof Jan De Waele

5 FRIDAY 27 TH APRIL 2018 SCHEDULE PAGE 2 NEURO CRITICAL CARE WEANING (continued) Prof Yasser Sakr & Dr Ashley Miller Prof Xavier Monnet & Dr Andrew Bentley Peri-operative management of patients with acute ischemic stroke Early mobilisation in neuro critical care Associate Prof Aarti Sarwal Prevention of delirium in ICU patients Questions Lunch MANAGEMENT Dr Andrew Bentley & NOAC reversal: a dream come true Peri-operative management of patients with pulmonary hypertension Levosimendan in severe heart failure Dr Christian Sitzwhol Management of the obese in Critical Care Dr Andrew Bentley Questions Coffee Break Avoiding failed extubation Weaning from prolonged ventilation Dr Andrew Bentley Questions Lunch RENAL Prof Michel Slama & Prof Daniel Lichtenstein Fluid challenges for oliguria - useful or a knee-jerk reaction Biomarkers for acute kidney injury Early vs late initiation of CRRT The dark side of CRRT Questions Coffee Break Cardiovascular physiology relevant to Intensive Care Prof Xavier Monnet Prof Bernard Cholley Dr Miguel Tavares Ultrasound in Acute Care - all you are afraid to ask Moderator: Dr Jonathan Wilkinson Dr Deepak Govil Simulation in ICU Associate Prof Aarti Sarwal Dr Zudin Puthucheary ROUND TABLE: Quality, safety, burnout and research in ICU - ask the experts Chairperson: Prof Fang Gao Smith Dr Nazir Lone Dr Ravi Kumar Dr Bronwen Connolly

FRIDAY 27 TH APRIL 2018 SCHEDULE PAGE 3 TOPICS 2 & Prof

35 How to recognise failing right ventricle Prof Michel

50 When to stop antibiotics in sepsis Prof Paul Dark 15.

15 Mechanisms of spread of antibiotic resistance genes;

6 FRIDAY 27 TH APRIL 2018 SCHEDULE PAGE 3 TOPICS 2 & Prof Paul Dark How to recognise failing right ventricle Prof Michel Slama When to stop antibiotics in sepsis Prof Paul Dark Mechanisms of spread of antibiotic resistance genes; are we in a losing struggle? Prof Steven Opal Questions CLOSING LECTURE & Prof Paul Dark Future of Intensive Care - the challenges Closing remarks ENDORSED BY

THURSDAY 11 TH APRIL 2019 SCHEDULE PAGE 1 16 TH ANNUAL CRITICAL CARE SYMPOSIUM ROYAL NORTHERN COLLEGE OF MUSIC, MANCHESTER

THURSDAY 11 TH APRIL 2019 SCHEDULE PAGE 1 08.00 08.45 Registration 08.45 09.00 Introduction Dr Peter Spronk KEYNOTE ADDRESS 09.00 09.30 On the other side of the stethoscope: when the intensivist becomes