POULTRY PRODUCTION SOLUTIONS. Consistent Solutions for Ever Changing Production Demands

Transcription

1 POULTRY PRODUCTION SOLUTIONS Consistent Solutions for Ever Changing Production Demands

2 POULTRY PRODUCTION CHALLENGES AND SOLUTIONS PATHOGEN EXPOSURE NATURAL DEFENSES BACKGROUND The Veterinary Feed Directive brought a wave of regulatory change across animal agriculture influencing producers, nutritionists and veterinarians to generate new strategies for antibiotic use. Additional pressure on antibiotic use in meat production is being driven by retailer and consumer demands with many companies already expanding the amount of antibiotic-free product offerings. Although controversial, the new paradigm of antibiotic use and push toward antibiotic-free (ABF) production requires cooperation across all aspects of poultry production to be successful. In 2016, Novus launched Project Horizon, an initiative to help producers reduce the need for antibiotics in their production systems. Project Horizon is an opportunity for Novus to work in partnership with producers to optimize health through nutrition, minimizing the need for antibiotic use. By addressing the nutritional needs for health, both prevention and response to health challenge, reliance on antibiotics can be reduced. MODULATE IMMUNE RESPONSE Designed to provide access to Novus s expertise in gut health, nutrition and management strategies, Project Horizon has a dedicated team of resources and people available. Novus s wide portfolio of solutions helps optimize performance and improve animal health, animal wellbeing, and profitability.

3 INCREASED PATHOGEN LOAD WITHOUT ANTIBIOTIC TREATMENT SOLUTION: DECREASE PATHOGEN LOAD Physiological and environmental stress can alter intestinal gut flora, resulting in increased opportunity for pathogenic bacterial overgrowth leading to disease and poor performance. To encourage the predominance of beneficial bacteria, feed supplementation with high quality ingredients is essential in order to promote a healthy gastrointestinal tract to combat stressors. Enzymes, organic acids and probiotics have been proven to lower the levels of pathogenic bacteria in poultry, decreasing mortality and condemnations while improving live performance and profitability. Enzymes aid in supporting a healthy digestive system and reducing nitrogen excretion levels. CIBENZA DP100 protease shows a reduction in levels of C. perfringens and an improvement in intestinal villi strength through a reduction in systemic inflammation (Figures 1, 2). Protease enzymes also aid in digestion by breaking down non-digestible proteins, which reduces digesta viscosity, optimizing energy and efficiency while minimizing feed cost. FIGURE 1. C. perfinges Counts in the lleum at 15 Days of Age Clostridium perfringens (log cfu) Control Without Protease High Protein With Protease Yan et al., 2011 FIGURE 2. CIBENZA DP100 Improves the Crypt:Villus After 14 Days of Age Value Crypt:Villus Control Without Protease High Protein With Protease Yan et al., 2011 Organic acids are another strategy for fighting against C. perfringens and other pathogens. Research indicates ACTIVATE WD decreases lesion scores and mortality rates in birds infected with necrotic enteritis (NE) by minimizing the impact and colonization of foodborne pathogens after establishing stable gut microflora (Figures 3, 4). ACTIVATE WD has also been proven to decrease the total percentage of Salmonella in the ceca improving overall gut health. FIGURE 3. Total Percentage of Ceca Salmonella Positive at 49 Days of Age Salmonella Positive (%) Nonmedicated ACTIVATE WD 0.04% ACTIVATE WD 0.08% Mead et al., 1999 FIGURE 4. Less NE Lesion Scores in the Gut of Broilers, Challenged with Coccidia spp. and C. perfringens, After Supplying ACTIVATE WD MAX Lesion Scores at Day Positive Control P<0.05 ACTIVATE WD MAX Dibner et al., 2002

4 Probiotics can be added to feed in order to beneficially alter and maintain a bird s gut microflora for protection against harmful bacteria. SPORULIN, a three strain direct-fed microbial, targets the production of bacteriocins and competes with pathogens for adhesion sites and nutrients along the GI tract, supporting gut development and health. SPORULIN research shows a decrease in mortality (Figure 5) by reducing the incidence and severity of NE. In addition to reducing the impact of NE on mortality and live performance, SPORULIN has been shown to reduce horizontal transmission of Salmonella (Figure 6) and reduce pathogenic E. coli (Figure 7) in broilers. FIGURE 5. Mortality Due to Necrotic Enteritis Decreases with SPORULIN Mortality (%) Salinomycin Salinomycin + SPORULIN Coccidiosis Vaccine Coccidiosis Vacci + SPORULIN Starter (Day 0-14) Grower (Day 14-28) Finisher (Day 28-35) Withdrawal (Day 35-42) Day 42 Cumulative Calvert et al., 2014 FIGURE 6. Horizontal Transmission in Broilers: Percentage of Salmonella Enteriditis Recovery Percentage (%) Control Contacts Liver/Spleen SPORULIN Contacts Ceca Internal Trial, 2013 FIGURE 7. Population of E. coli F18 in the Gastrointestinal Tract of Broiler Chicks CFU of E. coli Resistant to Nalidixic Acid (Log10) Day 1* Day 2 Day 5 Day 8 Day 11 Control SPORULIN * Before E.coli F18 inoculation Statistical difference (P<0.05) Stringfellow et al., 2012 When gut health is optimized, energy usage is targeted to gaining weight and increasing feed conversion. ACTIVATE WD and MINTREX chelated trace minerals work together to give birds an advantage in feed conversion as well as gain when suppressed by infection (Figure 8; Table 1). FIGURE 8. Adjusted Feed Conversion of MINTREX Versus Other Sources Adjusted FCR Hydroxy TM Amino Acid Complex 40 ppm Sulfate MINTREX Welch et al., 2015 TABLE 1. Improved Feed Conversion and Live Weight Gain with ACTIVATE WD Treatment Day 42 Day 49 Adj. Feed Conversion Avg. Live Wt. Gain Adj. Feed Conversion Avg. Live Wt. Gain Nonmedicated kg kg ACTIVATE WD 0.04% ACTIVATE WD 0.08% kg kg kg kg Parker et al., 2011

5 COMPROMISED STRUCTURAL INTEGRITY FROM INCREASED DISEASE SOLUTION: BOOST STRUCTURAL INTEGRITY AND IMMUNITY Bird development begins in ovo when the breeder hen transfers essential trace minerals to the embryo. The enrichment of the egg yolk with zinc, copper and manganese results in improved mineralization of the bone and connective tissue in the progeny. Zinc, copper and manganese are required to support collagen, elastin and keratin development that is essential for skeletal health. Zn Cu Mn ZINC found in every tissue of the body accumulates in the bones deficiency symptoms: poor growth and reproduction COPPER required for crosslinking collagen gives strength and elasticity in bone, shell and connective tissues MANGANESE important for cartilage development deficiency symptons: shortened, deformed skeletal structures and slipped tendons referred to as perosis Collagen and elastin make up approximately 30 percent of the total protein in birds and are essential for proper development, bird health and well-being. Hundreds of enzyme reactions depend on zinc, copper, and manganese. Structural integrity includes immunity and cellular health. The challenges of a commercial production environment require birds to have optimal immune function. MINTREX can lower lesion scores and boost gut health in birds challenged with disease (figure 9). In addition to improvements in structural integrity, MINTREX chelated trace minerals have demonstrated improved immune response to viral vaccines and have been shown to have a positive effect on plasma peroxide levels (Figure 10). FIGURE 9. Improved Tissue Integrity of Birds Supplemented with MINTREX FIGURE 10. Strengthened Immune Response with MINTREX Infectious Bronchitis Newcastle Disease P= P=0.02 Grade 1 and 2 Footpads, (%) Day 46 Day 54 Average Titer ITM MINTREX Average Titer ITM MINTREX Control MINTREX Manangi et al., 2010 Internal Novus Trial

6 INCREASED FEED COST DUE TO POOR FEED QUALITY SOLUTION: IMPROVE FEED QUALITY BY REDUCING FEED OXIDATION Feed cost accounts for approximately 70 percent of the total cost of broiler production. Stabilization of fats, meals and dietary lipids is critical for production of high quality feed. Properly stabilized fats and ingredients reduce the oxidative loss of energy, vitamins and pigments in feed formulations and promote optimum performance and efficiency of poultry production. Unstabilized ingredients in feeds can result in a variety of gut health issues associated with feed passage and flushing, which in turn lead to poor performance, compromised bird health and increased production cost. SANTOQUIN feed preservative is proven to prolong the shelf life of feeds, especially during non-optimal storage conditions (i.e. excess heat, moisture, etc.), leading to improved weight gain and feed conversion rates. PROLONG SHELF LIFE during non-optimal storage conditions SANTOQUIN is proven to improve feed conversion by two points and to reduce days to six pounds for production efficiency by 1.26 days (Figures 11, 12). IMPROVE weight gain and FCR FIGURE Data: Feed Conversion Ratio with Dried Distillers Grains in Diet FCR Average Jan-15 Feb-15 Mar-15 Apr-15 May-15 Jun-15 Jul-15 Aug-15 Sep-15 Oct-15 2 pts Nov-15 Dec-15 No SANTOQUIN SANTOQUIN Broiler Industry Statistical Reporting Services, 2015 FIGURE Data: Days to Six Pounds with Dried Distillers Grains in Diet Days Average Jan-15 Feb-15 Mar-15 Apr-15 May-15 Jun-15 Jul-15 Aug-15 No SANTOQUIN SANTOQUIN Sep-15 Oct Days Nov-15 Dec-15 Broiler Industry Statistical Reporting Services, 2015

7 NOVUS SOLUTIONS FOR POULTRY HEALTH A supplemental protease enzyme that optimizes digestion and absorption of nutrients, reducing the amount of anti-nutritive factors that pass through to the lower gastrointestinal tract. A blend of organic acids that creates an environment to support positive microflora balance and helps mitigate bacterial shed and spread. A direct-fed spore-based microbial that is an effective source of Bacillus subtilis that is proven to reduce pathogen levels and decrease feed conversion. Delivers the most bioavailable sources of Zn, Cu and Mn for physiological functions including a stronger immune system, improved gut microflora balance as a result of Cu supplementation, and improved oxidative balance. Manages gut level oxidative stress by stabilizing nutrients to support a healthy environment and improved animal oxidative balance for improved performance. SANTOQUIN also preserves the energy content of fats in complete feeds to optimize feed efficiency and reduce feed cost for gain. Delivers antimicrobial properties and enhances performance as the leading source of methionine in the North America.

8 Novus employs a dedicated team of employees and researchers committed to making poultry production more efficient and profitable in the face of ABF production. The Novus staff has more than 50 PhDs and DVMs dedicated to helping poultry producers realize greater efficiency and profitability. Through partnerships with scientists and universities on a global scale, we invent custom solutions for enhancing poultry health and producer profitability! Join us on our journey with Project Horizon! Novus International, Inc. 20 Research Park Dr. St. Charles, MO USA Products not available in all countries. NOTICE: While the information contained herein ( Information ) is presented in good faith and believed to be correct as of the date hereof, Novus International, Inc., does not guarantee satisfactory results from reliance upon such Information, disclaims all liability for any loss or damage arising out of any use of this Information or the products to which said Information refers and MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE OR OF ANY OTHER NATURE WITH RESPECT TO THE INFORMATION OR PRODUCTS, except as set forth in Novus s standard conditions of sale. Nothing contained herein is to be construed as a recommendation to use any product or process in conflict with any patent, and Novus International, Inc., makes no representation or warranty, express or implied, that the use thereof will not infringe any patent., ALIMET, MHA, SANTOQUIN, CIBENZA, ACTIVATE, SPORULIN, ZORIEN,and MINTREX are trademarks of Novus International, Inc., and are registered in the United States and other countries. TM ACIDOMATRIX is a trademark of Novus International, Inc Novus International, Inc. All rights reserved. 562_v1_R