Deep Brain Stimulation Surgery for Parkinson s Disease
|
|
|
- Lambert Wilkerson
- 6 years ago
- Views:
Transcription
1 Deep Brain Stimulation Surgery for Parkinson s Disease Demystifying Medicine 24 January 2012 Kareem A. Zaghloul, MD, PhD Staff Physician, Surgical Neurology Branch NINDS
2 Surgery for Parkinson s Disease Medically refractory PD Thalamotomy (VIM/VOP) Tremor suppression Risks of speech impairment, memory loss, and hemiparesis Pallidotomy (Posteroventral) Rigidity and bradykinesia Risks of visual deficit and speech impairment Perrine, K. et. al. (1998) Cognitive functioning after pallidotomy for refractory Parkinson s disease Journal of Neurology, Neurosurgery, and Psychiatry 65:
3 Indications FDA approved for: Parkinson s Disease (2002) Essential Tremor (1997) Dystonia (2003) OCD (HDE 2009)
4 Basal Ganglia
5 Basal Ganglia Circuitry
6 Parkinson s Disease
7 Parkinson s Disease Hammond, C et al (2007) Pathological synchronization in Parkinson s disease: networks, models, and treatments Trends in Neurosciences 30:
8 Parkinson s Disease Hammond, C et al (2007) Pathological synchronization in Parkinson s disease: networks, models, and treatments Trends in Neurosciences 30: Kuhn, A et al (2009) Pathological synchronisation in the subthalamic nucleus of patients with Parkinson s disease relates to both bradykinesia and rigidity Experimental Neurology 215:
9 Deep Brain Stimulation
10 Electrode Ablation
11 Parkinson s Disease
![High frequency stimulation Movement amplitude [% BL] Individual beta power [% BL] Kuhn, A et al (2008) High-frequency stimulation of the subthalamic nucleus suppresses oscillatory B activity in](/docs-images/80/81214191/images/12-1.jpg "patients with Parkinson s disease in parallel with improved motor performance Journal of Neuroscience 28: 6165-6173 Hammond, C et al (2007) Pathological synchronization in Parkinson s disease:")
12 High frequency stimulation Movement amplitude [% BL] Individual beta power [% BL] Kuhn, A et al (2008) High-frequency stimulation of the subthalamic nucleus suppresses oscillatory B activity in patients with Parkinson s disease in parallel with improved motor performance Journal of Neuroscience 28: Hammond, C et al (2007) Pathological synchronization in Parkinson s disease: networks, models, and treatments Trends in Neurosciences 30:
13 Basal Ganglia Courtesy of Kirk Finnis, Medtronic
14 Basal Ganglia
15 Basal Ganglia
16 Basal Ganglia Caudate
17 Basal Ganglia Caudate Putamen, GP
18 Basal Ganglia Caudate Putamen, GP Internal Capsule
19 Basal Ganglia Caudate Putamen, GP Internal Capsule Red Nucleus
20 Basal Ganglia Caudate Putamen, GP Internal Capsule Red Nucleus STN
21 Basal Ganglia Caudate Putamen, GP Internal Capsule Red Nucleus STN Substantia Nigra
22 Basal Ganglia
23 Basal Ganglia Red Nucleus
24 Basal Ganglia STN Red Nucleus
25 Stereotactic Surgery Victor Horsley & Robert Henry Clarke
26 Stereotactic Surgery Ernest Spiegel & Henry Wycis 1947 Spiegel, E et al (1947) Stereotaxic apparatus for operations on the human brain Science 106:
27 Stereotactic Neurosurgery
28 Stereotactic Neurosurgery
29 Anterior Commissure-Posterior Commissure
30 Anterior Commissure-Posterior Commissure
31 Anterior Commissure-Posterior Commissure
32 Anterior Commissure-Posterior Commissure
33 Anterior Commissure-Posterior Commissure
34 Stereotactic Neurosurgery
35 Stereotactic Neurosurgery
36 Microelectrode Recording (MER) Courtesy of Kirk Finnis, Medtronic
37 Microelectrode Recording (MER) Courtesy of Kirk Finnis, Medtronic
38 Microelectrode Recording (MER) Rt Type A Rt Type B STN SNpr I Hutchison, WD et al (1998) Neurophysiological Idenification of the Subthalamic Nucleus in Surgery for Parkinson s Disease Annals of Neurology 44(4):
39 Microelectrode Recording (MER)
40 Deep Brain Stimulation
41 Deep Brain Stimulation
42 Efficacy PD Weaver, FM et al (2009) Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson s disease JAMA 301: Andrade, P et al (2009) A systematic review of the efficacy of globus pallidus stimulation in the treatment of Parkinson s disease J Clin Neuro 16:
43 Efficacy Subthalamic Nucleus Rigidity and bradykinesia; ~40% reduction of medication Globus Pallidus Rigidity and bradykinesia Ventral Intermediate Nucleus (Thalamus) Tremor suppression
44 Efficacy Subthalamic Nucleus Rigidity and bradykinesia; ~40% reduction of medication Globus Pallidus Rigidity and bradykinesia Ventral Intermediate Nucleus (Thalamus) Tremor suppression Pedunculopontine Nucleus Gait and postural instability
45 Deep Brain Stimulation Courtesy of Kirk Finnis, Medtronic
46 Thank you
47
Deep Brain Stimulation for Parkinson s Disease & Essential Tremor
Deep Brain Stimulation for Parkinson s Disease & Essential Tremor Albert Fenoy, MD Assistant Professor University of Texas at Houston, Health Science Center Current US Approvals Essential Tremor and Parkinsonian
Deep Brain Stimulation: Indications and Ethical Applications
Deep Brain Stimulation Overview Kara D. Beasley, DO, MBe, FACOS Boulder Neurosurgical and Spine Associates (303) 562-1372 Deep Brain Stimulation: Indications and Ethical Applications Instrument of Change
PACEMAKERS ARE NOT JUST FOR THE HEART! Ab Siadati MD
PACEMAKERS ARE NOT JUST FOR THE HEART! Ab Siadati MD WHAT IS DEEP BRAIN STIMULATION? WHY SHOULD YOU CONSIDER DBS SURGERY FOR YOUR PATIENTS? HOW DOES DBS WORK? DBS electrical stimulation overrides abnormal
Deep Brain Stimulation and Movement Disorders
Deep Brain Stimulation and Movement Disorders Farrokh Farrokhi, MD Neurosurgery Maria Marsans, PA-C Neurosurgery Virginia Mason June 27, 2017 OBJECTIVES Understand the role of Deep Brain Stimulation (DBS)
Indications. DBS for Tremor. What is the PSA? 6/08/2014. Tremor. 1. Tremor. 2. Gait freezing/postural instability. 3. Motor fluctuations
Indications Deep brain stimulation for Parkinson s disease A Tailored Approach 1. Tremor 2. Gait freezing/postural instability Wesley Thevathasan FRACP DPhil.Oxf 3. Motor fluctuations Consultant Neurologist,
Surgical Treatment for Movement Disorders
Surgical Treatment for Movement Disorders Seth F Oliveria, MD PhD The Oregon Clinic Neurosurgery Director of Functional Neurosurgery: Providence Brain and Spine Institute Portland, OR Providence St Vincent
EMERGING TREATMENTS FOR PARKINSON S DISEASE
EMERGING TREATMENTS FOR PARKINSON S DISEASE Katerina Markopoulou, MD, PhD Director Neurodegenerative Diseases Program Department of Neurology NorthShore University HealthSystem Clinical Assistant Professor
COGNITIVE SCIENCE 107A. Motor Systems: Basal Ganglia. Jaime A. Pineda, Ph.D.
COGNITIVE SCIENCE 107A Motor Systems: Basal Ganglia Jaime A. Pineda, Ph.D. Two major descending s Pyramidal vs. extrapyramidal Motor cortex Pyramidal system Pathway for voluntary movement Most fibers originate
Deep Brain Stimulation: Surgical Process
Deep Brain Stimulation: Surgical Process Kia Shahlaie, MD, PhD Assistant Professor Bronte Endowed Chair in Epilepsy Research Director of Functional Neurosurgery Minimally Invasive Neurosurgery Department
Basal Ganglia. Steven McLoon Department of Neuroscience University of Minnesota
Basal Ganglia Steven McLoon Department of Neuroscience University of Minnesota 1 Course News Graduate School Discussion Wednesday, Nov 1, 11:00am MoosT 2-690 with Paul Mermelstein (invite your friends)
VL VA BASAL GANGLIA. FUNCTIONAl COMPONENTS. Function Component Deficits Start/initiation Basal Ganglia Spontan movements
BASAL GANGLIA Chris Cohan, Ph.D. Dept. of Pathology/Anat Sci University at Buffalo I) Overview How do Basal Ganglia affect movement Basal ganglia enhance cortical motor activity and facilitate movement.
Anatomy of the basal ganglia. Dana Cohen Gonda Brain Research Center, room 410
Anatomy of the basal ganglia Dana Cohen Gonda Brain Research Center, room 410 danacoh@gmail.com The basal ganglia The nuclei form a small minority of the brain s neuronal population. Little is known about
Surgical Treatment of Movement Disorders. Surgical Treatment of Movement Disorders. New Techniques: Procedure is safer and better
Surgical Treatment of Movement Stephen Grill, MD, PHD Johns Hopkins University and Parkinson s and Movement Center of Maryland Surgical Treatment of Movement Historical Aspects Preoperative Issues Surgical
Punit Agrawal, DO Clinical Assistant Professor of Neurology Division of Movement Disorders OSU Department of Neurology
Deep Brain Stimulation for Movement Disorders Punit Agrawal, DO Clinical Assistant Professor of Neurology Division of Movement Disorders OSU Department of Neurology History of DBS 1 History of DBS 1987
Lecture XIII. Brain Diseases I - Parkinsonism! Brain Diseases I!
Lecture XIII. Brain Diseases I - Parkinsonism! Bio 3411! Wednesday!! Lecture XIII. Brain Diseases - I.! 1! Brain Diseases I! NEUROSCIENCE 5 th ed! Page!!Figure!!Feature! 408 18.9 A!!Substantia Nigra in
Deep Brain Stimulation: Patient selection
Deep Brain Stimulation: Patient selection Halim Fadil, MD Movement Disorders Neurologist Kane Hall Barry Neurology Bedford/Keller, TX 1991: Thalamic (Vim) DBS for tremor Benabid AL, et al. Lancet. 1991;337(8738):403-406.
DEEP BRAIN STIMULATION
DEEP BRAIN STIMULATION Non-Discrimination Statement and Multi-Language Interpreter Services information are located at the end of this document. Coverage for services, procedures, medical devices and drugs
Neurodegenerative Disease. April 12, Cunningham. Department of Neurosciences
Neurodegenerative Disease April 12, 2017 Cunningham Department of Neurosciences NEURODEGENERATIVE DISEASE Any of a group of hereditary and sporadic conditions characterized by progressive dysfunction,
Parkinson disease: Parkinson Disease
Surgical Surgical treatment treatment for for Parkinson disease: Parkinson Disease the Present and the Future the Present and the Future Olga Klepitskaya, MD Associate Professor of Neurology Co-Director,
The Surgical Management of Essential Tremor
The Surgical Management of Essential Tremor International Essential Tremor Foundation Learning About Essential Tremor: Diagnosis and Treatment Options Albuquerque, NM September 24, 2005 Neurosurgeon Overview:
Basal ganglia Sujata Sofat, class of 2009
Basal ganglia Sujata Sofat, class of 2009 Basal ganglia Objectives Describe the function of the Basal Ganglia in movement Define the BG components and their locations Describe the motor loop of the BG
Functional Neuroanatomy and Physiology for Movement Disorders
Functional Neuroanatomy and Physiology for Movement Disorders Chang, Won Seok Division of Stereotactic and Functional Neurosurgery, Department of Neurosurgery, Brain Research Institute, Yonsei University
10/13/2017. Disclosures. Deep Brain Stimulation in the Treatment of Movement Disorders. Deep Brain Stimulation: Objectives.
Deep Brain Stimulation in the Treatment of Movement Disorders Disclosures None Eleanor K Orehek, M.D. Movement Disorders Specialist Noran Neurological Clinic 1 2 Objectives To provide an overview of deep
NIH, American Parkinson Disease Association (APDA), Greater St. Louis Chapter of the APDA, McDonnell Center for Higher Brain Function, Barnes-Jewish
Mechanism of Action of Deep Brain Stimulation In Parkinson Disease Samer D. Tabbal, M.D. Associate Professor of Neurology Washington University at St Louis Department of Neurology June 2011 Conflict of
Parkinsonism or Parkinson s Disease I. Symptoms: Main disorder of movement. Named after, an English physician who described the then known, in 1817.
Parkinsonism or Parkinson s Disease I. Symptoms: Main disorder of movement. Named after, an English physician who described the then known, in 1817. Four (4) hallmark clinical signs: 1) Tremor: (Note -
Surgical Treatment: Patient Edition
Parkinson s Disease Clinic and Research Center University of California, San Francisco 505 Parnassus Ave., Rm. 795-M, Box 0114 San Francisco, CA 94143-0114 (415) 476-9276 http://pdcenter.neurology.ucsf.edu
Deep Brain Stimulation
Deep Brain Stimulation for Parkinson s Disease 2 Blair Ford, M.D. Associate Professor, Department of Neurology Columbia University Medical Center Scientific Editor for the Parkinson s Disease Foundation
BASAL GANGLIA. Dr JAMILA EL MEDANY
BASAL GANGLIA Dr JAMILA EL MEDANY OBJECTIVES At the end of the lecture, the student should be able to: Define basal ganglia and enumerate its components. Enumerate parts of Corpus Striatum and their important
Deep Brain Stimulation for Treatment of Parkinson s Disease Deep brain stimulation, Parkinson s disease, subthalamic nucleus, stereotactic surgery
ISPUB.COM The Internet Journal of Neuromonitoring Volume 7 Number 1 Deep Brain Stimulation for Treatment of Parkinson s Disease Deep brain stimulation, Parkinson s disease, subthalamic nucleus, stereotactic
Dr. Farah Nabil Abbas. MBChB, MSc, PhD
Dr. Farah Nabil Abbas MBChB, MSc, PhD The Basal Ganglia *Functions in association with motor cortex and corticospinal pathways. *Regarded as accessory motor system besides cerebellum. *Receive most of
Alim-Louis Benabid and Mahlon DeLong win the 2014 Lasker~DeBakey Clinical Medical Research Award
Alim-Louis Benabid and Mahlon DeLong win the 2014 Lasker~DeBakey Clinical Medical Research Award The 2014 Lasker~DeBakey Clinical Medical Research Award recognizes the extraordinary efforts of two physician-scientists,
Deep Brain Stimulation. Is It Right for You?
Deep Brain Stimulation Is It Right for You? Northwestern Medicine Deep Brain Stimulation What is DBS? Northwestern Medicine Central DuPage Hospital is a regional destination for the treatment of movement
Troubleshooting algorithms for common DBS related problems in tremor and dystonia
Troubleshooting algorithms for common DBS related problems in tremor and dystonia Elena Moro, MD, PhD, FEAN, FAAN Movement Disorder Center, CHU Grenoble, Grenoble Alpes University, INSERM U1216, Grenoble,
Making Things Happen 2: Motor Disorders
Making Things Happen 2: Motor Disorders How Your Brain Works Prof. Jan Schnupp wschnupp@cityu.edu.hk HowYourBrainWorks.net On the Menu in This Lecture In the previous lecture we saw how motor cortex and
Functional Distinctions
Functional Distinctions FUNCTION COMPONENT DEFICITS Start Basal Ganglia Spontaneous Movements Move UMN/LMN Cerebral Cortex Brainstem, Spinal cord Roots/peripheral nerves Plan Cerebellum Ataxia Adjust Cerebellum
Basal Ganglia George R. Leichnetz, Ph.D.
Basal Ganglia George R. Leichnetz, Ph.D. OBJECTIVES 1. To understand the brain structures which constitute the basal ganglia, and their interconnections 2. To understand the consequences (clinical manifestations)
WHAT DEFINES YOPD? HANDLING UNIQUE CONCERNS REBECCA GILBERT, MD, PHD VICE PRESIDENT, CHIEF SCIENTIFIC OFFICER, APDA MARCH 14, 2019
WHAT DEFINES YOPD? HANDLING UNIQUE CONCERNS REBECCA GILBERT, MD, PHD VICE PRESIDENT, CHIEF SCIENTIFIC OFFICER, APDA MARCH 14, 2019 YOUNG ONSET PARKINSON S DISEASE Definition: Parkinson s disease diagnosed
Extrapyramidal Motor System. Basal Ganglia or Striatum. Basal Ganglia or Striatum 3/3/2010
Extrapyramidal Motor System Basal Ganglia or Striatum Descending extrapyramidal paths receive input from other parts of motor system: From the cerebellum From the basal ganglia or corpus striatum Caudate
The motor regulator. 1) Basal ganglia/nucleus
The motor regulator 1) Basal ganglia/nucleus Neural structures involved in the control of movement Basal Ganglia - Components of the basal ganglia - Function of the basal ganglia - Connection and circuits
For more information about how to cite these materials visit
Author(s): Peter Hitchcock, PH.D., 2009 License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution Non-commercial Share Alike 3.0 License: http://creativecommons.org/licenses/by-nc-sa/3.0/
Damage on one side.. (Notes) Just remember: Unilateral damage to basal ganglia causes contralateral symptoms.
Lecture 20 - Basal Ganglia Basal Ganglia (Nolte 5 th Ed pp 464) Damage to the basal ganglia produces involuntary movements. Although the basal ganglia do not influence LMN directly (to cause this involuntary
A. General features of the basal ganglia, one of our 3 major motor control centers:
Reading: Waxman pp. 141-146 are not very helpful! Computer Resources: HyperBrain, Chapter 12 Dental Neuroanatomy Suzanne S. Stensaas, Ph.D. March 1, 2012 THE BASAL GANGLIA Objectives: 1. What are the main
A. General features of the basal ganglia, one of our 3 major motor control centers:
Reading: Waxman pp. 141-146 are not very helpful! Computer Resources: HyperBrain, Chapter 12 Dental Neuroanatomy Suzanne S. Stensaas, Ph.D. April 22, 2010 THE BASAL GANGLIA Objectives: 1. What are the
GBME graduate course. Chapter 43. The Basal Ganglia
GBME graduate course Chapter 43. The Basal Ganglia Basal ganglia in history Parkinson s disease Huntington s disease Parkinson s disease 1817 Parkinson's disease (PD) is a degenerative disorder of the
Surgical treatment for Parkinson's disease. Citation Hong Kong Practitioner, 1999, v. 21 n. 3, p
Title Surgical treatment for Parkinson's disease Author(s) Leung, GKK; Hung, KN; Fan, YW Citation Hong Kong Practitioner, 1999, v. 21 n. 3, p. 106-115 Issued Date 1999 URL http://hdl.handle.net/10722/45396
EVALUATION OF SURGERY FOR PARKINSON S DISEASE
EVALUATION OF SURGERY FOR PARKINSON S DISEASE A Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology Mark Hallett, MD; Irene Litvan, MD; and the Task Force
symptoms of Parkinson s disease EXCEPT.
M. Angele Theard, M.D Asst. Professor, Washington University, St. Louis, MO Quiz team; Shobana Rajan, M.D; Suneeta Gollapudy, MD; Verghese Cherian, M.D, M. Angele Theard, MD This quiz is being published
Prospective Memory as a Specific Form of Task Switching. Intention and Executive Control
Prospective Memory as a Specific Form of Task Switching Intention and Executive Control Yehene E, Meiran N, Soroker N Taskalternationcostwithoutask alternation:measuringintentionality. A behavioral dissociation
Over the last 20 years, Deep Brain Stimulation (DBS)
Deep Brain Stimulation in Parkinson s Disease: Past, Present, and Future Though it has been underutilized over the past two decades, deep brain stimulation is an effective intervention for many individuals
Strick Lecture 4 March 29, 2006 Page 1
Strick Lecture 4 March 29, 2006 Page 1 Basal Ganglia OUTLINE- I. Structures included in the basal ganglia II. III. IV. Skeleton diagram of Basal Ganglia Loops with cortex Similarity with Cerebellar Loops
CN V! touch! pain! Touch! P/T!
CN V! touch! pain! Touch! P/T! Visual Pathways! L! R! B! A! C! D! LT! E! F! RT! G! hypothalamospinal! and! ALS! Vestibular Pathways! 1. Posture/Balance!!falling! 2. Head Position! 3. Eye-Head Movements
THE EFFECTS OF SUBTHALAMIC NUCLEUS DEEP BRAIN STIMULATION ON VOCAL TRACT DYNAMICS IN PARKINSON S DISEASE
11 th Bienniel Speech Motor Control Conference, Colonial Williamsburg, Virginia, 2002. THE EFFECTS OF SUBTHALAMIC NUCLEUS DEEP BRAIN STIMULATION ON VOCAL TRACT DYNAMICS IN PARKINSON S DISEASE Steven Barlow,
See Policy CPT/HCPCS CODE section below for any prior authorization requirements
Effective Date: 1/1/2019 Section: SUR Policy No: 395 1/1/19 Medical Policy Committee Approved Date: 8/17; 2/18; 12/18 Medical Officer Date APPLIES TO: Medicare Only See Policy CPT/HCPCS CODE section below
High-Field in vivo Visualization of the Human Globus Pallidus Using 7T MRI
Niederer 1 High-Field in vivo Visualization of the Human Globus Pallidus Using 7T MRI Abstract In the past several decades the introduction of high-resolution, three-dimensional modeling techniques have
Basal Ganglia General Info
Basal Ganglia General Info Neural clusters in peripheral nervous system are ganglia. In the central nervous system, they are called nuclei. Should be called Basal Nuclei but usually called Basal Ganglia.
Deep Brain Stimulation
Deep Brain Stimulation Policy Number: 7.01.63 Last Review: 8/2017 Origination: 8/2001 Next Review: 8/2018 Policy Blue Cross and Blue Shield of Kansas City (Blue KC) will provide coverage for deep brain
DBS efficacia, complicanze in cronico e nuovi orizzonti terapeutici
DBS efficacia, complicanze in cronico e nuovi orizzonti terapeutici TECNICHE DI NEUROMODULAZIONE Invasiva: odeep Brain Stimulation Non Invasiva: o Transcranial Magnetic Stimulation (TMS) o Transcranial
Effects of nicotine on neuronal firing patterns in human subthalamic nucleus. Kim Scott Mentor: Henry Lester SURF seminar, January 15, 2009
Effects of nicotine on neuronal firing patterns in human subthalamic nucleus Kim Scott Mentor: Henry Lester SURF seminar, January 15, 2009 Smoking tobacco protects against Parkinson s Disease (PD). Identical
A Parkinson s Disease and related disorders
A 3.5.2 Parkinson s Disease and related disorders 10 November 2016 Marinela Vavla marinela.vavla@kcl.ac.uk Learning objectives Basal ganglia: components and localization (inter)connections and functions
As clinical experience with deep-brain stimulation (DBS) of
ORIGINAL RESEARCH K.V. Slavin K.R. Thulborn C. Wess H. Nersesyan Direct Visualization of the Human Subthalamic Nucleus with 3T MR Imaging BACKGROUND AND PURPOSE: Electrical stimulation of the subthalamic
Neuroinformatics. (credits: Daniel Novák, Tomáš Sieger) 12th March Lecture 4: Case study - Deep brain stimulation for Parkinson s disease
Neuroinformatics Eduard Bakštein (credits: Daniel Novák, Tomáš Sieger) 12th March 2015 Lecture 4: Case study - Deep brain stimulation for Parkinson s disease Overview Why this lecture? Because... Parkinson
Deep Brain Stimulation For Parkinson s Disease
Deep Brain Stimulation For Parkinson s Disease What s new in brain circuit training Associate Professor Robert Wilcox Flinders University & University of South Australia Neurology Department, Flinders
SUPPLEMENTAL DIGITAL CONTENT
SUPPLEMENTAL DIGITAL CONTENT FIGURE 1. Unilateral subthalamic nucleus (STN) deep brain stimulation (DBS) electrode and internal pulse generator. Copyright 2010 Oregon Health & Science University. Used
Palladotomy and Pallidal Deep Brain Stimulation
Palladotomy and Pallidal Deep Brain Stimulation Parkinson s disease Parkinson s Disease is a common neurodegenerative disorder that affects about 1:100 individuals over the age of 60. In a small percentage
Pre- and Postoperative MR Evaluation of Stereotactic Pallidotomy
AJNR Am J Neuroradiol 19:1075 1080, June 1998 Pre- and Postoperative MR Evaluation of Stereotactic Pallidotomy Michael C. Cohn, Patricia A. Hudgins, Scott K. Sheppard, Phillip A. Starr, and Roy A. E. Bakay
Basal nuclei, cerebellum and movement
Basal nuclei, cerebellum and movement MSTN121 - Neurophysiology Session 9 Department of Myotherapy Basal Nuclei (Ganglia) Basal Nuclei (Ganglia) Role: Predict the effects of various actions, then make
Critical Review: Can sub-thalamic deep brain stimulation (STN-DBS) improve speech output in patients with Parkinson s Disease?
Copyright 2007, Iulianella, I. Critical Review: Can sub-thalamic deep brain stimulation (STN-DBS) improve speech output in patients with Parkinson s Disease? Iulianella, I. M.Cl.Sc. (SLP) Candidate School
Subthalamic Nucleus Deep Brain Stimulation (STN-DBS)
Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) A Neurosurgical Treatment for Parkinson s Disease Parkinson s Disease Parkinson s disease is a common neurodegenerative disorder that affects about
DBS Programming. Paul S Fishman MD, PhD University of Maryland School of Medicine PFNCA 3/24/18
DBS Programming Paul S Fishman MD, PhD University of Maryland School of Medicine PFNCA 3/24/18 Disclosure The University of Maryland has received research funding form InSightec and the Focused Ultrasound
Supplementary Information for Decreased activity of single subthalamic nucleus neurons in Parkinson patients responding to placebo
Supplementary Information for Decreased activity of single subthalamic nucleus neurons in Parkinson patients responding to placebo Fabrizio Benedetti, 1,2 Luana Colloca, 1,2 Elena Torre, 1 Michele Lanotte,
Property of Chonghao Zhao, MD, Ph.D.
UCLA Orofacial Pain Lecture Series # 2 March 17 th 2011 Overview of Basal Ganglion, Thalamus, Hypothalamus, Brainstem, and Spinal Cord Neuroanatomy and MR Anatomy Chong-hao Zhao, MD, PhD American Board
Motor Fluctuations in Parkinson s Disease
Motor Fluctuations in Parkinson s Disease Saeed Bohlega, MD, FRCPC Senior Distinguished Consultant Department of Neurosciences King Faisal Specialist Hospital & Research Centre Outline Type of fluctuations
Surgical Management of Parkinson s Disease
Surgical Management of Parkinson s Disease Shyamal H. Mehta MD, PhD Assistant Professor of Neurology, Movement Disorders Division Mayo Clinic College of Medicine Mayo Clinic, Arizona 2016 MFMER slide-1
Transcranial sonography in movement disorders
Transcranial sonography in movement disorders Uwe Walter 1st Residential Training of the European Society of Neurosonology and Cerebral Hemodynamics September 7-12, 2008 Bertinoro, Italy Department of
Connections of basal ganglia
Connections of basal ganglia Introduction The basal ganglia, or basal nuclei, are areas of subcortical grey matter that play a prominent role in modulating movement, as well as cognitive and emotional
MOVEMENT OUTLINE. The Control of Movement: Muscles! Motor Reflexes Brain Mechanisms of Movement Mirror Neurons Disorders of Movement
MOVEMENT 2 Dr. Steinmetz 3 OUTLINE The Control of Movement: Muscles! Motor Reflexes Brain Mechanisms of Movement Mirror Neurons Disorders of Movement Parkinson s Disease Huntington s Disease 1 4 TYPES
Name of Policy: Deep Brain Stimulation
Name of Policy: Deep Brain Stimulation Policy #: 347 Latest Review Date: June 2013 Category: Surgery Policy Grade: B Background/Definitions: As a general rule, benefits are payable under Blue Cross and
modulation of multiple brain networks.
Neuroanatomy of Deep Brain Stimulation: modulation of multiple brain networks. Dr. med. Ettore A. Accolla Maladie de Parkinson: un diagnostic clinique 1. Bradykinésie 2. Tremblement de repos (4-6 Hz) 3.
Parkinson s Disease Webcast January 31, 2008 Jill Ostrem, M.D. What is Parkinson s Disease?
Parkinson s Disease Webcast January 31, 2008 Jill Ostrem, M.D. Please remember the opinions expressed on Patient Power are not necessarily the views of UCSF Medical Center, its medical staff or Patient
Ablative procedures for the treatment of Parkinson s disease
Ablative procedures for the treatment of Parkinson s disease Zeiad Y. Fayed MD Neurosurgery department Ain Shams University 1 2 Pallidotomy Pallidotomy Indications: Non tremor dominant PD Levodopa induced
Parkinson s Disease and Cortico-Basal Ganglia Circuits
Continuing Medical Education 213 Parkinson s Disease and Cortico-Basal Ganglia Circuits Ming-Kai Pan, Chun-Hwei Tai, Chung-Chin Kuo Abstract- Cortico-basal ganglia circuit model has been studied extensively
SYNCHRONIZATION OF PALLIDAL ACTIVITY IN THE MPTP PRIMATE MODEL OF PARKINSONISM IS NOT LIMITED TO OSCILLATORY ACTIVITY
SYNCHRONIZATION OF PALLIDAL ACTIVITY IN THE MPTP PRIMATE MODEL OF PARKINSONISM IS NOT LIMITED TO OSCILLATORY ACTIVITY Gali Heimer, Izhar Bar-Gad, Joshua A. Goldberg and Hagai Bergman * 1. INTRODUCTION
Shaheen Shaikh, M.D. Assistant Professor of Anesthesiology, University of Massachusetts Medical center, Worcester, MA.
Shaheen Shaikh, M.D. Assistant Professor of Anesthesiology, University of Massachusetts Medical center, Worcester, MA. Shobana Rajan, M.D. Associate staff Anesthesiologist, Cleveland Clinic, Cleveland,
BME 701 Examples of Biomedical Instrumentation. Hubert de Bruin Ph D, P Eng
BME 701 Examples of Biomedical Instrumentation Hubert de Bruin Ph D, P Eng 1 Instrumentation in Cardiology The major cellular components of the heart are: working muscle of the atria & ventricles specialized
Parkinson's Disease KP Update
Parkinson's Disease KP Update Andrew Imbus, PA-C Neurology, Movement Disorders Kaiser Permanente, Los Angeles Medical Center No disclosures "I often say now I don't have any choice whether or not I have
Kinematic Modeling in Parkinson s Disease
Kinematic Modeling in Parkinson s Disease Alexander Hui Department of Bioengineering University of California, San Diego La Jolla, CA 92093 alexhui@ucsd.edu Abstract Parkinson s disease is a slowly progressing
ORIGINAL CONTRIBUTION. Subthalamic Stimulation in Parkinson Disease
Subthalamic Stimulation in Parkinson Disease A Multidisciplinary Approach ORIGINAL CONTRIBUTION J. L. Houeto, MD; P. Damier, MD, PhD; P. B. Bejjani, MD; C. Staedler, MD; A. M. Bonnet, MD; I. Arnulf, MD;
1/2/2019. Basal Ganglia & Cerebellum a quick overview. Outcomes you want to accomplish. MHD-Neuroanatomy Neuroscience Block. Basal ganglia review
This power point is made available as an educational resource or study aid for your use only. This presentation may not be duplicated for others and should not be redistributed or posted anywhere on the
Basal Ganglia. Today s lecture is about Basal Ganglia and it covers:
Basal Ganglia Motor system is complex interaction between Lower motor neurons (spinal cord and brainstem circuits) and Upper motor neurons (pyramidal and extrapyramidal tracts) plus two main regulators
The webinar will begin momentarily. Tractography-based Targeting for Functional Neurosurgery
Welcome The webinar will begin momentarily. Tractography-based Targeting for Functional Neurosurgery Vibhor Krishna, MD, SM Assistant Professor, Center for Neuromoduation, Dept. of Neurosurgery and Dept.
Imaging alone versus microelectrode recording guided targeting of the STN in patients with Parkinson s disease
CLINICAL ARTICLE Imaging alone versus microelectrode recording guided targeting of the STN in patients with Parkinson s disease Christopher S. Lozano, BSc, 1 Manish Ranjan, MBBS, 1 Alexandre Boutet, MD,
Long-Term Effects of Thalamic Deep Brain Stimulation on Force Control in a Patient with Parkinson s Disease-Driven Action Tremor
Long-Term Effects of Thalamic Deep Brain Stimulation on Force Control in a Patient with Parkinson s Disease-Driven Action Tremor Karen L. Francis, PhD* Waneen W. Spirduso, EdD Tim Eakin, PhD Pamela Z.
Biomedical Instrumentation
Biomedical Instrumentation BME 523 (Fall 2009) Final Project Report Deep Brain Stimulation for Movement Disorder Diseases by HAO SU Submitted to Prof. Yitzhak Mendelson Date of Submission: December 18,
First described by James Parkinson in his classic 1817 monograph, "An Essay on the Shaking Palsy"
Parkinson's Disease First described by James Parkinson in his classic 1817 monograph, "An Essay on the Shaking Palsy" Parkinson s disease (PD) is a neurological disorder characterized by a progressive
Deep Brain Stimulation (DBS)
Deep Brain Stimulation (DBS) [For the list of services and procedures that need preauthorization, please refer to www.mcs.com.pr go to Comunicados a Proveedores, and click Cartas Circulares.] Medical Policy:
Validation of basal ganglia segmentation on a 3T MRI template
Validation of basal ganglia segmentation on a 3T MRI template Claire Haegelen, Nicolas Guizard, Pierrick Coupé, Florent Lalys, Pierre Jannin, Xavier Morandi, D. Louis Collins To cite this version: Claire
Deep Brain Stimulation. Description. Section: Surgery Effective Date: April 15, 2015
Subject: Deep Brain Stimulation Page: 1 of 22 Last Review Status/Date: March 2015 Deep Brain Stimulation Description Deep brain stimulation (DBS) involves the stereotactic placement of an electrode into
Movement Disorders. Psychology 372 Physiological Psychology. Background. Myasthenia Gravis. Many Types
Background Movement Disorders Psychology 372 Physiological Psychology Steven E. Meier, Ph.D. Listen to the audio lecture while viewing these slides Early Studies Found some patients with progressive weakness
Medical Policy Deep Brain Stimulation. Description. Related Policies. Policy. Subsection. Effective Date February 27,
7.01.63 Deep Brain Stimulation Section 7.0 Surgery Subsection Effective Date February 27, 2015 Original Policy Date December 18, 2009 Next Review Date February 2016 Medical Policy Description Deep brain