2014 Faculty Senate Awards

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1 2014 Faculty Senate Awards Mission College of Pharmacy Research Award Nominee Name: David Lee Phone: Department: FA.OSU/OHSU College of Pharmacy Nomination Submissions and Required Documents Included in Packet 1. Nomination Letters 1 a. Jon Furuno 2. Summary 3. CV

2 Faculty Senate Awards To the Selection Committee, Please accept this letter of nomination for Dr. David Lee for the OHSU Research Award. Dr. Lee is a relatively new faculty member, who joined the faculty of the Oregon State University/Oregon Health & Science University College of Pharmacy as an Assistant Professor in September Nonetheless, in that time, Dr. Lee has amassed an impressive research portfolio which forecasts well for a successful research career. Dr. Lee s training is in clinical pharmacy and pharmacology and has chosen geriatric pharmacotherapy and pharmacoepidemiology as his primary research and clinical interests. To support this work, Dr. Lee recently received a New Investigator Award from the Medical Research Foundation of Oregon and has previously received support from the American Society of Clinical Pharmacology and Therapeutics. Dr. Lee has seven peer-reviewed publications including two, recent, first author papers in JAMA Internal Medicine and Medical Care. Both are large studies of the effect of cardiovascular medications on important cardiovascular and pulmonary outcomes as a well physical activity. These findings are sure to garner interest from the scientific and lay community given the high prevalence of both the diseases under study and use of these drugs, which is likely to increase given recent guidelines. In short, Dr. Lee is an excellent scientist addressing important public health questions and he would be an excellent choice for the OHSU Research Award. Jon P. Furuno, Ph.D. Associate Professor

3 Summary Since starting my position at OHSU/OSU College of Pharmacy in September of 2011, my research has been focused on the adverse effects of statins on physical activity, muscle mass, and physical function in older adults. The first of these was just accepted to JAMA Internal Medicine (in press), Statins and Physical Activity in Older Men: The Osteoporotic Fractures in Men Study (MrOS). Two other studies are currently under way are looking at statins and muscle mass in men (MrOS) and women (Women s Health Initiative). Both of these manuscripts are currently in preparation. Other firstauthored publications include Journal of Pharmacy Technology (cognitive impairment and medication complexity) and Medical Care (use of beta-blockers in coronary and pulmonary disease) examined how medical treatment can affect medical care in older adults. My future interests include exploring barriers to care after discharge from the hospital or emergency department (visits) in older adults. These events are generally precipitating a large change in prescription usage, some may or may not be for the best. This research will include interviews of older patients from OHSU hospitalizations and ED visits and follow the patients for subsequent hospitalization or ED visit. I m excited for these research opportunities at OHSU/OSU.

4 Program Director/Principal Investigator (Last, First, Middle): Lee, David S. BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME Lee, David S era COMMONS USER NAME (credential, e.g., agency login) DAVLEE POSITION TITLE Assistant Professor, Department of Pharmacy Practice EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.) DEGREE INSTITUTION AND LOCATION MM/YY FIELD OF STUDY (if applicable) Georgia Institute of Technology, Atlanta GA BS 12/99 Chemistry Virginia Commonwealth University, School of Pharmacy, Richmond VA Virginia Commonwealth University, School of Pharmacy, Richmond VA Pharm.D. 08/09 Pharmacy Ph.D. 08/09 Clinical Pharmacology Yale School of Medicine, New Haven CT Postdoctoral Fellow 08/11 Geriatric Epidemiology A. Personal Statement B. Positions and Honors Positions and Employment Postdoctoral Fellow, Geriatric Clinical Epidemiology and Aging-related Research, Yale School of Medicine, Section of Geriatrics, New Haven CT Pharmacy Fellow, Geriatric Consult Clinic, West Haven Veterans Administration Hospital, West Haven CT Licensed Pharmacist, State of Connecticut 2011-Present Assistant Professor, Oregon State University/Oregon Health and Science University, College of Pharmacy, Portland OR 2012-Present Licensed Pharmacist, State of Oregon 2013-Present Assistant Professor, Oregon State University, Center for Healthy Aging Research, Corvallis OR 2014-Present Clinical pharmacist, Oregon Health and Science University, Department of Pharmacy Services and Geriatrics consult, Portland OR Other Experience and Professional Memberships 2005-Present Member, American Association of Pharmaceutical Scientists Chair, VCU Student-chapter of American Association of Pharmaceutical Scientists 2006-Present Member, American College of Clinical Pharmacology 2006-Present Member, American Society for Clinical Pharmacology and Therapeutics Fellow, American Foundation for Pharmaceutical Education Member, Connecticut Chapter, American Society of Consultant Pharmacists Member, Coalition for Medication Misuse and Abuse in the Elderly, New Haven CT 2009-Present Member, American Geriatrics Society 2010-Present Scientific Awards Selection Task Force, American Society for Clinical Pharmacology and Therapeutics PHS 398/2590 (Rev. 06/09) Page 1 Biographical Sketch

5 Program Director/Principal Investigator (Last, First, Middle): Lee, David S Present Member, American Society of Consultant Pharmacists, Research Council 2013-Present OHSU Faculty Senate, OSU/OHSU College of Pharmacy Representative Senate committees: Faculty Senate Awards Committee, Education Policy Committee Honors 2004 Inducted, Rho Chi, Pharmacy Honor Society 2006 Virginia Commonwealth University, Kamlesh Thakker Award for Excellence in Research and Scholarship, Richmond VA Fellow, American Foundation for Pharmaceutical Education 2008 Dissertation Scholar Award, Southern Regional Education Board, Scholar s Program 2009 Trainee Award, American College of Clinical Pharmacology, for outstanding abstract submitted for presentation to the 2009 ACCP Annual Meeting, San Antonio TX 2009 Wayne A. Colburn Memorial Award, American College of Clinical Pharmacology for most outstanding research presentation at the 2009 ACCP Annual Meeting, San Antonio TX Young Investigator Award, American Society for Clinical Pharmacology and Therapeutics March Member of the Month, American Society for Clinical Pharmacology and Therapeutics 2013 Abstract award, American Society for Consultant Pharmacists, 2013 Annual Meeting, Seattle WA C. Selected Peer-reviewed Publications Manuscripts: Lee DSH, De Rekeneire N, Hanlon JT, Gill TM, Bauer DC, Meibohm B, Harris TB, Jeffery SM. Cognitive Impairment and Medication Complexity in Community-Living Older Adults: The Health, Aging and Body Composition Study. J Pharm Technol 2012;28: Albrecht JS, Gruber-Baldini AL, Fromme EK, McGregor JC, Lee DSH, Furuno JP. Quality of Hospice Care for Patients with Dementia. J Am Geriatr Soc 61: , 2013 Lee DSH, Markwardt S, McAvay GJ, Gross CP, Goeres L, Ling H, Peduzzi P, Han L, Dodson J, Tinetti ME. Effect of Beta Blockers on Cardiac and Pulmonary Events and Death in Older Adults with Cardiovascular Disease and Chronic Obstructive Pulmonary Disease. Medical Care 52:S45-S51, March Tinetti ME, Han L, Lee DSH, McAvay GJ, Peduzzi P, Gross CP, Zhou B, Lin HQ. Anti-hypertensive medications and serious fall injuries in older adults. JAMA Intern Med, Published online February 24, Lorgunapai SJ, Grammas M, Lee DSH, McAcay G, Charpentier P, Tinetti ME, Potential Therapeutic Competition in Community-living Older Adults in the U.S.: Use of Medications That May Adversely Affect a Coexisting Condition. PLOS ONE, 2014;9(2):e Lee DSH, Markwardt S, Goeres L, Lee CG, Eckstom E, Williams C, Fu R, Orwoll E, Cawthon P, Stefanick M, Mackey D, Bauer D, Nielson C. Statins and Physical Activity in Older Men: the Osteoporotic Fractures in Men (MrOS) Study. JAMA Intern Med, In press. Tinetti ME, Han L, McAvay GJ, Lee DSH, Peduzzi P, Dodson JA, Gross CP, Zhou B, Lin HQ. Anti- Hypertensive medications and cardiovascular events in older adults with multiple chronic conditions. PLOS ONE, In press. D. Research Support Completed Research Support Medical Research Foundation of Oregon New Investigator Award Lee DSH (PI) 12/01/12 11/30/13 Title: The Effects of Statins on Lean Body Mass, Strength and Performance, and Physical Activity in Community-living Older Men Role: Principale investigator PHS 398/2590 (Rev. 06/09) Page 2 Biographical Sketch

6 Program Director/Principal Investigator (Last, First, Middle): Lee, David S. American Society for Clinical Pharmacology and Therapeutics Young Investiagator Award Lee DSH (PI) 7/01/10 6/30/11 Title: Effect of Beta Blockers on Cardiac and Pulmonary Events and Death in Older Adults with Cardiovascular Disease and Chronic Obstructive Pulmonary Disease. Role: Principale investigator NIH/NIA T32 Research Fellowship Geriatric Clinical Epidemiology and Aging-related Research Yale University, School of Medicine, Department of Internal Medicine, Section of Geriatrics Gill TM (PI) 09/01/09 09/14/11 Title: Cognitive impairment and medication complexity in older community-living adults: The Health, Aging and Body Composition Study. Role: Postdoctoral Fellow PHS 398/2590 (Rev. 06/09) Page 3 Biographical Sketch

7 February 13, 2014 To whom it may concern, I write in strong support of Dr. David S. Lee s nomination for the Oregon Health and Science University Faculty Senate Research Award. I have known David since 2009, when he started as a postdoctoral fellow. I have found him to be an intelligent, hard-working, and a thorough researcher. Our work together has produced several important manuscripts in journals such as, Medical Care, PLOS ONE, and JAMA Internal Medicine. David s work explores the important field of therapeutic competition in older adults the problem of using medications for one medical condition, but that may worsen their overall health. In addition, his own independent research has been published in Journal of Pharmacy Technology and JAMA Internal Medicine. These manuscripts have further enumerated the possible adverse effects of medications or medical conditions on overall health in older adults, including cognitive function and physical activity. For these reasons, I believe David is deserving of this award and I recommend him without reservation.

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