Name : PD Dr. Shrikant Ramesh Mulay
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1 Name : PD Dr. Shrikant Ramesh Mulay Qualification : Ph.D. (Human Biology) Habilitation (Experimental Medicine) Date of birth : Nationality : Indian Address for correspondence : Klinikum der Universität Medizinische Klinik und Poliklinik IV Schillerstrasse 42, Munich, Germany Shrikant_Ramesh.Mulay@med.uni-muenchen.de Research experience 2017-till date Assistant Professor, Faculty of Medicine, Medical Clinic and Policlinic IV, Ludwig-Maximilians University (LMU) of Munich, Germany Principal Investigator at the Division of Nephrology, Ludwig Maximilians University of Munich, Germany. Research areas: Necroinflammation (cell death and inflammation loop) in tissue injury, repair/regeneration and remodeling/fibrosis and Pathomechanisms of crystallopathies Post-doctoral research fellow at Division of Nephrology, with the research group of Prof. Hans- Joachim Anders, Ludwig Maximilians University of Munich, Germany. Research areas: Molecular mechanisms of crystal induced cell death Doctoral Research Fellow at the Division of Nephrology, Ludwig Maximilians University of Munich, Germany. Research project: Role of murine double minute (MDM)-2 in kidney injury and repair Research Scholar at Dept. of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India. Research project: Effect of combination of aspirin and telmisartan on STZ induced type 1 diabetic nephropathy in SD rats Education Habilitation (Experimental Medicine) (Dr. habil.), Faculty of Medicine, Medical Clinic and Policlinic IV, Ludwig-Maximilians University (LMU) of Munich, Germany Ph.D. (Human Biology) (Dr. rer. hum. biol.), Division of Nephrology, University of Munich (LMU), Munich, Germany (summa-cum-laude) [Distinction] M.S. Pharm. (Pharmacology & Toxicology), Dept. of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India [Distinction] B. Pharmacy, NDMVP s College of Pharmacy, University of Pune, Nashik, India [Distinction]
2 Awards and Scholarships ERA-EDTA Stanely Shaldon Young Investigators Award 2018 Copenhagen, Denmark European Renal Association International Award - Rolf-Becker Prize from Faculty of Medicine, Ludwig Maximilians University of Munich, Germany - Travel Grant Award for European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) at Vienna, Austria - Best Scientific Abstract Award at the German Society of Nephrology (DGfN) meeting at Berlin, Germany - Outstanding Scientific Presentation Best abstract presented by Young scientist at European Renal Association- European Dialysis and Transplant Association (ERA-EDTA) at London, UK - Travel Grant Award for European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) at London, UK Travel Grant Award for Oxaluria and Hyperoxaluria Foundation meeting at Chicago, Illinois, USA Wissenschaftliches Institute of Nephrology (WiNe) Prize WiNe-Scientific Institute for Nephrology, German Kidney Center (Deutsche Nierenzentren (DN) e.v.), Germany - Hugo Wilhelm von Ziemssen-Prize from Medizinische Klinik und Poliklinik IV, Ludwig Maximilians University of Munich, Germany The publication Murine double minute-2 links inflammation and tubular healing in acute kidney injury of mice. Kidney Int Jun; 81(12): is selected for Faculty of 1000: post publication peer review Travel Grant Award for European Renal Association- European Dialysis and Transplant Association (ERA-EDTA) at Paris, France Research Fellowship at National Institute of Pharmaceutical Education and Research (NIPER) SAS Nagar, Punjab, India Certificates Federation of European Laboratory Animal Science Associations (FELASA), Category C Academic Teacher Training Certificates, Munich, Germany 2012 Federation of European Laboratory Animal Science Associations (FELASA), Category B Pharmacist: Registered Pharmacist in Maharashtra State Pharmacy Council, India
3 Invited lectures in International Meetings 2018 Copenhagen, Denmark, 2018 Inflammasome activation in chronic kidney diseases Indian Pharmacological Society Conference (IPSCON) 2017, Mumbai, India, 2018 Novel mechanisms of crystalline nephropathies German Society for Clinical Chemistry and Laboratory Medicine (DGKL), Annual Meeting, Mannheim, Germany, Crystallopathies How crystals kill cells? - German Society of Nephrology (DGfN) Annual Meeting, Berlin, Germany, Necroinflammation in kidney disease Vienna, Austria, Beta-hydroxybutyrate inhibits NLRP3 mediated inflammation and delays progressive renal failure during primary hyperoxaluria related kidney stone disease - OxalEurope Spring Meeting, Munich, Germany, Novel therapeutic strategies for hyperoxaluria related kidney stone disease - German Society of Nephrology (DGfN) Annual Meeting, Berlin, Germany, Murine double minute-2 blockade ameliorate severe glomerulonephritis London, UK Calcium oxalate crystals induce RIPK3-MLKL mediated necroptosis in tubular cells - German Society of Nephrology (DGfN) Annual Meeting, Berlin, Germany, 2014 Progressive oxalate nephropathy depends on TNFR1/2 because they are needed for CaOx crystal adhesion to tubule epithelium - Oxalosis and Hyperoxaluria Foundation (OHF) meeting Chicago, USA, 2014 Progressive oxalate nephropathy depends on TNFR1/2 because they are needed for CaOx crystal adhesion to tubule epithelium European Renal Cell Study Group (ERCGS) meeting Oxford, UK, 2013 Calcium oxalate crystals activate renal cells to secrete TNF which drives renal inflammation and acute kidney injury European Renal Cell Study Group (ERCGS) meeting Riva del Garda, Italy, 2011 Role of murine double minute (MDM)-2 in ischemic renal injury IGSDHD Workshop, Cologne, Germany, 2009 Effect of aspirin in combination with telmisartan on STZ induced type 1 diabetic nephropathy
4 Poster Presentations in International Meetings (First or Last author only) 2018 Copenhagen, Denmark, 2018 Crystal nephrotoxicity involves two distinct molecular pathways of regulated necrosis - American Society of Nephrology (ASN) San Diego, USA, Calcium oxalate crystal-induced acute kidney injury involves RIPK3-MLKL mediated tubular cell necroptosis American Society of Nephrology (ASN) Philadelphia, USA, 2014 Progressive oxalate nephropathy depends on TNFR1/2 because they are needed for CaOx crystal adhesion to tubule epithelium 2013 Istanbul, Turkey 2013 Progressive oxalate nephropathy depends on TNFR1/2 because they are needed for CaOx crystal adhesion to tubule epithelium American Society of Nephrology (ASN) San Diego, USA, 2012 Murine double minute (MDM)-2 mediates podocyte loss, proteinuria, and subsequent tubular injury and interstitial fibrosis in progressive focal-segmental glomerulosclerosis Paris, France 2012 Calcium oxalate crystals induce renal inflammation and acute kidney injury by activating NLRP3 inflammasome-mediated interleukin-1β secretion in renal dendritic cells - American Society of Nephrology (ASN) Philadelphia, USA, 2011 Murine double minute-2 links inflammation and tubular healing in acute kidney injury of mice 2011 Prague, Czech Republic 2011 Murine double minute-2 in inflammation and tubular repair during acute kidney injury International symposium on Nuclear Architecture & Chromatin Dynamics, India, 2008 Calorie restriction reduces the progression of diabetic nephropathy involving changes in epigenetic modifications of histone H3 Industry Collaborations Industry Name Inositec AG, Zurich, Switzerland Role Principal Investigator (LMU Munich) Project Title Validation and Efficacy of a Novel Therapy for Hyperoxaluric Kidney Stone Disease Expert Evaluation Activities for Research Journals Cardiovascular Research - Journal of Visual Experiments - Kidney International Reports - American journal of physiology and renal physiology - Kidney International
5 JCI Insights - International Journal of Molecular Sciences - Mediators of Inflammation - Cardiovascular Research - Kidney International - Pharmacological Reports BMC Nephrology - PLoS One Nephrology Dialysis Transplant (NDT) Editorial Activities for Research Journals 2017 Guest Editor on a Special Issue Journals Frontiers in Immunology (IF 6.43) and Frontiers in Pharmacology (IF 4.4) Title Nano- and Microparticle-induced Cell Death, Inflammation, and Immune Responses Co-Editors Prof. Hans-Joachim Anders, Germany; Prof. Rostyslav Bilyy, Ukraine; Prof. Alexander Gabibov, Russia; Prof. Martin Herrmann, Germany. Lead Guest Editor on a Special Issue Journal Mediators of Inflammation (IF 3.23) Title Role of the Innate Immune System in Maintaining Homeostasis or Regaining Homeostasis after Injury Co-guest Editors Dr. Onkar P. Kulkarni, India; Dr. Julia Lichtnekert, USA; Prof. Hans-Joachim Anders, Germany. Number of PubMed Publications (as of Aug, 2018) First author Co-author Last/Corresponding Total Impact Factor H Index Publications Publications Author publications (ISI Web of Science) ISI Web of Science= Google scholar=21 List of Publications
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