YANNICK MARCHALANT, PH.D.

Size: px

Start display at page:

Download "YANNICK MARCHALANT, PH.D."

Melvin Page
5 years ago
Views:

1 YANNICK MARCHALANT, PH.D. THE OHIO STATE UNIVERSITY PSYCHOLOGY DEPARTMENT 1835 NEIL AVENUE COLUMBUS, OH PHONE (614) FAX (614) FRENCH CITIZEN ACADEMIC EXPERIENCE 2008 to present: Research Assistant Professor, The Ohio State University, Columbus, OH. Research interest: Influence of endocannabinoids on normal and pathological aging, particularly on neurogenesis and neuroinflammation to 2008: Postdoctoral researcher, The Ohio State University, Columbus, OH, with Dr. Gary L. Wenk; Research Interest: Role of the endocannabinoid system in the regulation of inflammation and aging in rodents : Postdoctoral Fellow, Division of Neural Systems, Memory & Aging, University of Arizona, Tucson, AZ, with Dr. Gary L. Wenk. Research Interests: Role of inflammation in a transgenic mouse and aging rodent model of Alzheimer disease. 2004: Ph.D. Biology, Medicine and Health Care, option Molecular and Cellular Aspects of Biology, University of Caen, France: Dissertation Title: Physiological mechanisms of cerebral activation : Modulatory role of the galaninergic and the ascending cholinergic system in the relationship between cerebral blood flow, metabolism and neuronal activity in the rat whiskers stimulation paradigm 2000: M.S. in Cellular Biology option Neurosciences, University of Caen, France. 1998: B.S. in Biochemistry option Immunology and Neurosciences, University of Caen, France. TEACHING EXPERIENCE 2008: Lecturer: Barbiturates and Benzodiazepines and The opioid system in course Drugs, Brain and Behaviour, Department of Psychology, The Ohio State University, Columbus, OH. 2008: Lecturer: Dementia and Aging in course behavioural neuroscience, Department of Neuroscience, The Ohio State University, Columbus, OH 2007: Lecturer: Learning and Memory in course Introduction to Psychobiology, Department of Psychology, The Ohio State University, Columbus, OH. 2007: Lecturer: Barbiturates and Benzodiazepines and The cholinergic system in course Drugs, Brain and Behaviour, Department of Psychology, The Ohio State University, Columbus, OH. 2006: Lecturer: Learning and Memory in course Introduction to Psychobiology, Department of Psychology, The Ohio State University, Columbus, OH. 2006: Lecturer: Barbiturates and Benzodiazepines and The cholinergic system in course Drugs, Brain and Behaviour, Department of Psychology, The Ohio State University, Columbus, OH. 2005: Lecturer: Barbiturates and Benzodiazepines in course Drugs, Brain and Behaviour, Department of Psychology, University of Arizona, Tucson. AZ. 2001: Lecturer (1 semester, biology module) in Psychology (first year), University of Caen.

2 PUBLICATIONS 2009: Marchalant Y., Brothers H.M., Norman G.H., Karelina K., Devries A.C., Wenk G.L.: CANNABINOIDS ATTENUATE THE EFFECTS OF AGING UPON NEUROINFLAMMATION AND NEUROGENESIS.. Neurobiol. Dis., in press 2008: Marchalant Y., Cerbai F., Brothers H.M., Wenk G.L.: CANNABINOID RECEPTOR STIMULATION IS ANTI-INFLAMMATORY AND IMPROVES MEMORY IN OLD RATS. Neurobiology of aging 29(12): : Marchalant Y., Brothers, H.M., Wenk G.L: NEUROINFLAMMATION IN YOUNG AND AGED RATS: INFLUENCE OF ENDOCANNABINOIDS AND CAFFEINE. Journal of neuroimmunology vol. 197 (2): : Marchalant Y., Brothers, H.M., Wenk G.L.: INFLAMMATION AND AGING: CAN ENDOCANNABINOIDS HELP?. Biomedecine and Pharmacotherapy vol. 62 (4), : Marchalant Y, Rosi S, Wenk GL : ANTI-INFLAMMATORY PROPERTY OF THE CANNABINOID AGONIST WIN IN A RAT MODEL OF CHRONIC BRAIN INFLAMMATION. Neuroscience Feb 23;144(4): : Barbelivien A, Vaussy C, Marchalant Y, Maubert E, Bertrand N, Beley A, Roussel S, Mackenzie ET, Dauphin F.: DEGENERATION OF THE BASALOCORTICAL PATHWAY FROM THE CORTEX INDUCES A FUNCTIONAL INCREASE IN GALANINERGIC MARKERS IN THE NUCLEUS BASALIS MAGNOCELLULARIS OF THE RAT. J Cereb Blood Flow Metab Nov;24(11): : Gsell W., De Sadeleer C., Marchalant Y., MacKenzie E.T., Schumann P., Dauphin F. THE USE OF CEREBRAL BLOOD FLOW AS AN INDEX OF NEURONAL ACTIVITY IN FUNCTIONNAL NEUROIMAGING : EXPERIMENTAL AND PATHOPHYSIOLOGICAL CONSIDERATIONS. (2000) J. Chem. Neuroanat. 20 (3-4) Submitted or in preparation: Marchalant Y., Brothers H.M., Wenk G.L.: CANNABINOID RECEPTOR AGONIST STIMULATES NEUROGENESIS IN OLD RATS. Submitted to Neuroscience Marchalant Y., Barbelivien A., Brothers H.M., Schumann-bard P., Wenk G.L.., Dauphin F.: GALANIN INNERVATES CORTICAL VESSELS AND THAT INNERVATION IS ALTERED FOLLOWING AN IMMUNOSELECTIVE LESION OF THE NUCLEUS BASALIS MAGNOCELLULARIS Submitted to Journal of cerebral blood flow and metabolism Brothers H.M., Marchalant Y., Burgess L., Wenk G.L.: EFFECT OF CHRONIC NEUROINFLAMMATION ON DOPAMINERGIC CELLS OF THE SUBSTANTIA NIGRA AND NEUROGENESIS In preparation for J.Neuroscience BOOK CHAPTERS 2008: Wenk, G.L. & Marchalant, Y. Neuropharmacology. In: G.G. Berntson & J.T. Cacioppo, (Eds.) Handbook of Neuroscience for the Behavioral Sciences, John Wiley & Sons, in press. GRANTS AND AWARDS 2005: Grant from the Philippe Foundation, Inc.: Role of the endocannabinoid system in the regulation of inflammation in a rodent model of Alzheimer disease. 2003: One year grant from the Lilly Institute: Influence of the cholinergic basalocortical pathway on the relationships between cerebral blood flow, metabolism and neuronal activity.

3 2002: One year grant from the French Pharmacological Society: Influence of the cholinergic basalocortical pathway on the relationships between cerebral blood flow, metabolism and neuronal activity : pharmacological study. 2002: First price poster (LARC, October 2002): Marchalant Y., Barbelivien A., Maubert E., Divoux D., MacKenzie E.T., Dauphin F. : Anatomical and functionnal evidence for the existence of an innervation of rat cerebrovascular vessels by galanin, french. INVITED PRESENTATIONS AND MEETING ATTENDANCE Invited presentations; 2009: Moderator of the debate on the legalization of Marijuana: heads versus feds with Steve Hager, editor of High Times and Bob Stutman, Ex director of the DEA in New York, Ohio State University, USA 2008: Coffee and marijuana may prevent Alzheimer s and Parkinson s disease, Society for Neuroscience, Washington DC, USA 2008: Influence du système cannabinoide sure la neuroinflammation et le vieillissement cérébral, Université de Bordeaux, France 2008: Influence du système cannabinoide sure la neuroinflammation et le vieillissement cérébral, Centre Cyceron, Caen, France 2007: Alzheimer s disease and Neuroinflammation, Ohio State University, USA 2007: Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats. International cannabinoid research society meeting, Saint sauveur, QC, Canada 2007: Of fire and Smoke: Neuroinflammation and aging. Ohio State University, USA 2001: Anatomical and functionnal evidence for the existence of an innervation of rat cerebrovascular vessels by galanin. European Congress of Cytometry Applied to Pathology, Caen, France. Poster presentation : 2008: Marchalant Y, Brothers H, L. Burgess, Wenk GL. Endocannabinoid effects on neuroinflammation and neurogenesis in aged rats, Society for Neuroscience meeting, Washington DC. Marchalant Y, Brothers H, Wenk GL. Role of endocannabinoides and Memantine on neuroinflammation, memory and neurogenesis in aged rats. International conference on Alzheimer s disease, July 2008, Chicago, USA. Brothers H.M., Cerbai F., Marchalant Y., Wenk G.L. Regional susceptibility to inflammation: neuron-glia interactions in the hippocampus and substantia nigra and rescue by the NMDA antagonist Memantine. Poster presented at the ICAD meeting, Chicago, Illinois. Wenk G.L., Brothers H.M., Marchalant Y. Neuron-Glia intercommunication during neuroinflammation associated with Alzheimer's disease and other neurodegenerative disorders. Poster presented at the ICAD meeting, Chicago, Illinois. Cerbai F, Brothers H.M., Marchalant Y., Giovannini M.G., Wenk G.L. Role of CD200 in neuron-glia intercommunication during inflammation. Poster presented at the FENS meeting, Geneva, Switzerland Wenk GL., Brothers H, Marchalant Y.: Neuron-glia intercommunication during neuroinflammation associated with Alzheimer s disease and other neurodegenerative disorders. International Behavioral Neuroscience society meeting, June 2008, St Thomas, Virgin Islands. Marchalant Y, Brothers H, Wenk GL. Neuroinflammation in young and aged rats: Influence of endocannabinoides and caffeine Neuroimmunology symposium, March 2008, Dublin, Ireland. 2007: Marchalant Y, Brothers H, Cerbai F, Wenk GL. Endocannabinoids receptors effects on

4 neuroinflammation and memory in aged rats. Neuropharmacolgy conference, November 2007, San diego, USA. Marchalant Y, Brothers H, Cerbai F, Wenk GL. Endocannabinoids receptors effects on neuroinflammation and memory in aged rats. Society for Neuroscience meeting, November 2007, San diego, USA. Brothers H, Marchalant Y, Cerbai F, Wenk GL. The effects of the adenosine receptor disease. Society for Neuroscience meeting, November 2007, San diego, USA Marchalant Y, Cerbai F, Brothers H, Wenk GL. Cannabinoid receptor stimulation is antiinflammatory and improves memory in old rats. Ohio Society for Neuroscience chapter meeting, April 2007, Columbus, OH, USA. Brothers H.M., Marchalant Y., Cerbai F., Wenk G.L. The effects of the adenosine receptor disease. Poster presented at the SfN Central Ohio Chapter meeting, Columbus, Ohio 2006: Marchalant Y, Cerbai F, Brothers H, Wenk GL. Endocannabinoids agonist effects on inflammation and aging in rats. Society for Neuroscience meeting, october 2006, Atlanta, USA. Cerbai F, Marchalant Y, Brothers H, Wenk GL. Do endocannabinoids regulate the MAP Kinase pathway on inflammation and aging? Society for Neuroscience meeting, october 2006, Atlanta, USA. Brothers H, Marchalant Y, Cerbai F, Wenk GL. The effects of the adenosine receptor disease. Society for Neuroscience meeting, october 2006, Atlanta, USA. Marchalant Y, Rosi S, Wenk GL : Anti-Inflammatory Actions of the Endocannabinoid System in a Rodent Model of Chronic Neuroinflammation. International conference on alzheimer s disease meeting, July 2006, Madrid, Spain. 2005: Marchalant Y, Rosi S, Wenk GL : Anti-inflammatory property of the cannabinoid agonist WIN in a neuroinflammation rat model of Alzheimer disease. Society for Neuroscience meeting, November 2005, Washington DC, USA. Rosi S; Vazdarjanova A, Ramirez-Amaya V, Marchalant Y, Worley P.F, Barnes C.A, Wenk G.L. : the consequences of neuroinflammation upon hippocampal immediate early gene expression can be reversed by the NMDA receptor antagonist Memantine. Society for Neuroscience meeting, November 2005, Washington DC, USA. 2003: Marchalant Y., Barbelivien A., MacKenzie E.T., Dauphin, F.: Anatomical and functionnal evidence for the existence of an innervation of rat cerebrovascular vessels by galanin. Brain03 congress, july 2003, calgary, Canada. 2002: Marchalant Y., Barbelivien A., Maubert E., Divoux D., MacKenzie E.T., Dauphin F. : Contribution à la mise en évidence d une innervation galaninergique des vaisseaux sanguins cérébraux intraparenchymateux chez le rat. Annual meeting of the LARC-Neurosciences, Caen, October Marchalant Y., Barbelivien A., Maubert E., Divoux D., MacKenzie E.T., Dauphin F. : contribution à la mise en evidence d une innervation galaninergique des vaisseaux sanguins cerebraux intraparenchymateux chez le rat. Annual meeting of on the IFR 47 (medical imagery and health care), Caen, April ADVISORY POSITIONS Reviewer for the following journals Journal of pharmacology and Experimental Therapeutics

5 Journal of Applied physiology Learning and Memory Molecular Neurobiology Neurobiology of Aging Neuroscience SOCIETY MEMBERSHIP Society for neuroscience International cannabinoid research society MEDIA COVERAGE OF RESEARCH Television: ABC news 2008, Columbus affiliates for the implication of my research in the treatment of Alzheimer s disease ( Journal, Magazine, newspapers: Marijuana and Alzheimer s disease coverage by: Msn.com ( Health Day, Time, Reuters, Bloomberg, Scientific American, Wired, WebMD, CBS News, Nature, Boston globe, New York Daily News (and journals in England, Spain, Brazil, Germany, India, Australia )

Yannick Marchalant Born in Bayonne, France, the 09/09/1975 French citizen

Yannick Marchalant Born in Bayonne, France, the 09/09/1975 French citizen Professional address: Central Michigan University Health Profession Building HP 2181 Mount Pleasasnt, MI, 48859, USA Academic Experience: