PROVINCIAL EXAMINATION MINISTRY OF EDUCATION BIOLOGY 12 GENERAL INSTRUCTIONS

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INSERT STUDENT I.D. NUMBER (PEN) STICKER IN THIS SPACE AUGUST 1999 PROVINCIAL EXAMINATION MINISTRY OF EDUCATION BIOLOGY 12 GENERAL INSTRUCTIONS 1. Insert the stickers with your Student I.D. Number (PEN) in the allotted spaces above and on the back cover of this booklet. Under no circumstance is your name or identification, other than your Student I.D. Number, to appear on this booklet. 2. Ensure that in addition to this examination booklet, you have an Examination Response Form. Follow the directions on the front of the Response Form. 3. Disqualification from the examination will result if you bring books, paper, notes or unauthorized electronic devices into the examination room. 4. All multiple-choice answers must be entered on the Response Form using an HB pencil. Multiple-choice answers entered in this examination booklet will not be marked. 5. For each of the written-response questions, write your answer in ink in the space provided in this booklet. 6. When instructed to open this booklet, check the numbering of the pages to ensure that they are numbered in sequence from page one to the last page, which is identified by END OF EXAMINATION. 7. At the end of the examination, place your Response Form inside the front cover of this booklet and return the booklet and your Response Form to the supervisor. 1999 Ministry of Education

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BIOLOGY 12 PROVINCIAL EXAMINATION Value Suggested Time 1. This examination consists of two parts: PART A: 50 multiple-choice questions 50 45 PART B: 10 written-response questions 50 75 Total: 100 marks 120 minutes 2. Electronic devices, including dictionaries and pagers, are not permitted in the examination room. 3. The time allotted for this examination is two hours.

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PART A: MULTIPLE CHOICE Value: 50 marks INSTRUCTIONS: Suggested Time: 45 minutes For each question, select the best answer and record your choice on the Response Form provided. Using an HB pencil, completely fill in the circle that has the letter corresponding to your answer. 1. Which of the following organelles is correctly matched with its product? A. nucleolus DNA B. mitochondria ATP C. Golgi apparatus lipid D. smooth endoplasmic reticulum protein 2. Which of the following organelles breaks down dead cells? A. nucleus B. lysosome C. Golgi apparatus D. rough endoplasmic reticulum - 1 - OVER

Use the following diagram to answer questions 3 and 4. X Y 3. The structure labelled X is composed mostly of A. glycogen and protein. B. nucleic acid and glycogen. C. protein and phospholipids. D. nucleic acid and phospholipids. 4. One function of the structure labelled Y is to A. replicate DNA. B. control cell division. C. digest food molecules. D. produce digestive enzymes. - 2 -

5. A substance which helps maintain a constant ph in a solution is a(n) A. salt. B. acid. C. base. D. buffer. Use the following diagram to answer question 6. H H O H O H N C C OH H N C C OH H H 2 O H H 6. The diagram illustrates a step in the A. hydrolysis of a protein. B. synthesis of an enzyme. C. production of nucleic acid. D. conversion of glucose molecules to starch. 7. The building blocks or monomers that make up carbohydrates are A. nucleotides. B. amino acids. C. monosaccharides. D. fatty acids and glycerol. 8. Compared to saturated fats, unsaturated fats contain less A. oxygen. B. glycerol. C. hydrogen. D. fatty acids. - 3 - OVER

9. The number of adenine bases in a DNA molecule equals the number of thymine bases because A. DNA contains equal numbers of all four bases. B. thymine always follows adenine on each DNA strand. C. DNA is made of alternating adenine and thymine bases. D. adenine on one strand bonds to thymine on the other strand. 10. The product of transcription is A. DNA. B. protein. C. mrna. D. a ribosome. 11. Which of the following molecules is a building block or monomer of RNA? A. CH 2 OH B. O H C OH C H OH C O H C H C OH CH 3 ( CH 2 ) 16 CH 3 ( CH 2 ) 16 C O C O O O CH 2 CH H OH CH 3 ( CH 2 ) 16 C O CH 2 C. H H O D. P N N H N C C H OH - 4 -

Use the following chart to answer question 12. Three-letter codons of messenger RNA, and the amino acids specified by the codons AAU AAC Asparagine CAU CAC Histidine GAU GAC Asparatic acid UAU UAC Tyrosine AAA AAG Lysine CAA CAG Glutamine GAA GAG Glutamic acid UAA UAG Stop ACU ACC ACA ACG Threonine CCU CCC CCA CCG Proline GCU GCC GCA GCG Alanine UCU UCC UCA UCG Serine AGU AGC AGA AGG Serine Arginine CGU CGC CGA CGG Arginine GGU GGC GGA GGG Glycine UGU UGC UGA UGG Cysteine Stop Tryptophan AUU AUC AUA AUG Isoleucine Methionine CUU CUC CUA CUG Leucine GUU GUC GUA GUG Valine UUU UUC UUA UUG Phenylalanine Leucine 12. A strand of DNA has the following bases: C A C G G C C If the adenine base was deleted, which amino acids would be coded for? A. valine, proline B. glycine, alanine C. proline, arginine D. glycine, arginine 13. The process by which new blood vessels supply a growing tumour is A. metastasis. B. promotion. C. malignancy. D. vascularization. - 5 - OVER

14. Which of the following is capable of changing a proto-oncogene into an oncogene? A. virus B. antibody C. bacterium D. lymphocyte 15. An experiment was carried out to study the carcinogenic effects of certain chemicals on mice. Similar amounts of these chemicals were applied to their skins over a 6-month period. The results are shown below. CHEMICAL X CHEMICAL Y CHEMICALS X AND Y CONTROL (NO TREATMENT) 18% developed skin tumours 0% developed skin tumours 84% developed skin tumours 1% developed skin tumours Given the results, which of the following statements is correct? A. Chemical Y is a promoter. B. Chemical X can act only as a promoter. C. Chemical Y can act only as an initiator. D. Neither X nor Y is an initiator or a promoter. 16. Molecules in the cell membrane that function as receptors are A. proteins. B. glycerol. C. cholesterol. D. phospholipids. - 6 -

Use the following diagrams to answer question 17. Initial Two hours later Cl Na + Cl starch glucose protein Na + glucose starch protein H 2 O H 2 O Cl starch Na + protein glucose H 2 O starch protein Cl H 2 O Na + glucose Selectively Permeable Membrane Selectively Permeable Membrane 17. The diagrams illustrate that the membrane selects according to the A. size of the molecules. B. temperature of the solution. C. concentration of the molecules. D. electronic charge of the molecules. Use the following diagram to answer question 18. 18. The diagram shows a white blood cell ingesting a bacterium. The bacterium enters the white blood cell by A. diffusion. B. pinocytosis. C. phagocytosis. D. active transport. - 7 - OVER

19. Enzymes function to increase the rate of a metabolic reaction by A. denaturing the substrate. B. adding energy to the reaction. C. decreasing the energy of activation. D. increasing the concentration of the reactants. Use the following graphs to answer question 20. Graph 1 Graph 2 X Amount of Product (mg) Amount of Product (mg) 0 15 30 0 15 30 Time (minutes) Time (minutes) 20. Graph 1 represents the rate of reaction between lipase and its substrate. In graph 2, what occurred at time X that caused the change in the reaction? A. Fat was added. B. The ph was changed from 5 to 8. C. A competitive inhibitor was added. D. The temperature of the reaction was raised to 100 C. - 8 -

Use the following diagram to answer questions 21 and 22. X Y W Z 21. The structure labelled X releases a substance after the ingestion of A. fat. B. starch. C. protein. D. carbohydrate. 22. Digestion of peptides and absorption of their products occurs in which of the structures? A. W B. X C. Y D. Z - 9 - OVER

23. The reaction shown below is catalyzed by secretions from which organs? A. pancreas and liver B. liver and duodenum C. stomach and pancreas D. duodenum and stomach protein + H 2 O peptides 24. Increasing the secretion of insulin would have which of the following effects? A. decreased blood sugar B. decreased metabolic rate C. increased protein synthesis D. increased digestion of carbohydrate 25. High levels of toxins in the blood may indicate a problem with the function of the A. liver. B. stomach. C. pancreas. D. small intestine. Use the following characteristics to answer question 26. one-way valves thin elastic layer near skeletal muscle 26. The characteristics above describe which type of vessel? A. vein B. artery C. arteriole D. capillary - 10 -

Use the following diagram to answer question 27. X 27. The structure labelled X is the A. iliac vein. B. renal vein. C. subclavian vein. D. posterior vena cava. - 11 - OVER

Use the following diagram to answer question 28. W X Y Z 28. Which letter indicates a portal vein? A. W B. X C. Y D. Z 29. Oxygen is delivered to the heart muscle by the A. aorta. B. carotid artery. C. coronary artery. D. pulmonary artery. - 12 -

30. A person s blood pressure was measured at five blood vessels and plotted on the graph below. Blood Pressure (mm of Hg) Heart X Tissues Heart The reading taken at X would be at the A. renal artery. B. pulmonary vein. C. posterior vena cava. D. peritubular capillaries. - 13 - OVER

Use the following diagram to answer question 31. X 31. In the fetus, the function of the structure labelled X is to A. take blood to the lungs. B. ensure adequate blood flow to the brain. C. return blood from the placenta to the heart. D. direct some of the blood away from the lungs. 32. Blood capillaries and lymph capillaries both A. filter bacteria. B. have one-way valves. C. contain red blood cells. D. have walls which are one-cell thick. - 14 -

Use the following information to answer question 33. transport gases maintain body temperature protect the body against blood loss produce hormones that stimulate metabolism carry digestive enzymes to the small intestine 33. How many of the above are functions of the blood? A. two B. three C. four D. five 34. Which of the following correctly matches structure with function? A. platelets provide immunity B. plasma proteins carry oxygen C. red blood cells carry carbon dioxide D. white blood cells initiate blood clotting - 15 - OVER

Use the following graph to answer question 35. Nutrient Use During Starvation carbohydrates in cells stored fats plasma proteins Quantity of Nutrients Stored in Body 0 4 8 Weeks of Starvation 35. The graph illustrates how the body consumes stored nutrients during a prolonged period of starvation. After eight weeks, A. blood pressure will increase. B. fluids will accumulate in tissues. C. glycogen production will increase. D. hemoglobin will not release oxygen. - 16 -

Use the following diagram to answer question 36. Y X W Z 36. Which area indicated in the diagram is the location of the AV node? A. W B. X C. Y D. Z - 17 - OVER

Use the following diagram to answer question 37. X 37. The structure labelled X is the A. larynx. B. trachea. C. bronchus. D. diaphragm. 38. Inhalation is caused by A. the diaphragm moving up and the ribs moving in. B. the diaphragm moving up and the ribs moving out. C. the diaphragm moving down and the ribs moving in. D. the diaphragm moving down and the ribs moving out. - 18 -

Use the following graph to answer question 39. 30 Average Breathing Rate (breaths per minute) 20 10 0 Time 39. Which of the following would cause the effect shown? A. increased oxygen in the blood B. increased numbers of red blood cells C. increased carbon dioxide in the blood D. decreased concentration of hydrogen ions 40. The exchange of oxygen and carbon dioxide in external respiration occurs by A. osmosis. B. diffusion. C. active transport. D. facilitated diffusion. 41. Which of the following reactions occurs in a capillary of the leg? A. Hb + H + HHb B. HbCO 2 Hb + CO 2 C. Hb + oxygen HbO 2 D. H + + HCO 3 H 2 CO 3-19 - OVER

Use the following diagram to answer questions 42 and 43. X Y W 6 4 7 4 8 Z 42. The structure labelled X is a(n) A. node. B. axon. C. synapse. D. dendrite. V 43. If an impulse started at V, it would travel to A. W and X. B. W and Z. C. X and Z. D. Y and Z. - 20 -

Use the following diagram to answer question 44. X Y 44. If molecule X causes depolarization at Y, what could X be? A. sodium ions B. calcium ions C. acetylcholine D. acetylcholinesterase 45. Which of the following is a true statement about the sympathetic and parasympathetic nervous systems? A. Sympathetic system causes increased rates of digestion while the parasympathetic system causes decreased rates of digestion. B. Sympathetic system causes decreased breathing rate while the parasympathetic system causes increased breathing rate. C. Sympathetic system causes constriction of the iris while the parasympathetic system causes dilation of the iris. D. Sympathetic system causes increased heart rate while the parasympathetic system decreases heart rate. - 21 - OVER

Use the following diagram to answer question 46. Y X W Z 46. At which location would the greatest concentration of glucose be found? A. W B. X C. Y D. Z 47. The inability to regulate the concentration of sodium ions in the blood could be due to improper functioning of the A. adrenal cortex, since it produces ADH. B. adrenal cortex, since it produces aldosterone. C. adrenal medulla, since it produces ADH. D. adrenal medulla, since it produces aldosterone. - 22 -

48. Increased secretion of FSH (follicle-stimulating hormone) will result in increased production of A. sperm. B. progesterone. C. seminal fluid. D. human chorionic gonadotropin (HCG). 49. The part of a sperm cell containing the greatest number of mitochondria is the A. head. B. flagellum. C. acrosome. D. mid-piece. X Use the following diagram to answer question 50. W Y Z 50. In which area does fertilization normally occur? A. W B. X C. Y D. Z This is the end of the multiple-choice section. Answer the remaining questions directly in this examination booklet. - 23 - OVER

PART B: WRITTEN RESPONSE Value: 50 marks INSTRUCTIONS: 1. Use a pen for this part of the examination. 2. Write your answers in the space below the questions. Suggested Time: 75 minutes 3. Organization and planning space has been incorporated into the space allowed for answering each question. 4. You may not need all of the space provided to answer each question. Use the following diagram to answer question 1. CH 2 OH H C OH C H OH C O H C H C OH H OH 1. a) Identify the molecule above. (1 mark) b) What is the general term given to polymers formed from this molecule? (1 mark) c) List two biological functions of these polymers. (2 marks) i) ii) - 24 -

2. Using the table below, list three differences between RNA and DNA. (3 marks: 1 mark for each contrasting pair) RNA DNA - 25 - OVER

Use the following diagram to answer question 3. outside inside Na + Na + Na + P P P Na + Na + Na + P P P Na + Na + Na + P X membrane 3. a) Identify the process shown in the diagram above. (1 mark) b) Give one example in which this process is used in the body. (1 mark) c) Describe the function of the molecule represented by P P P : (1 mark) d) What is the function of molecule X? (1 mark) - 26 -

Use the following diagrams to answer question 4. Y 2 glucose molecules O X 4. a) The diagrams illustrate a reaction that occurs in the small intestine. Give the specific name for each of the following. Molecule X: (1 mark) Molecule Y: (1 mark) b) In a laboratory experiment, substance Y was added in increasing amounts until it eventually had no effect on the rate of the reaction. Explain why. (1 mark) c) A solution containing lead ions was added to the reaction. How will the addition of this solution affect the reaction? Explain why. (2 marks) - 27 - OVER

Use the following diagram to answer question 5. X Y Z 5. a) State two functions of structure Z. (2 marks) i) ii) - 28 -

b) For each of the following structures, list one enzyme it secretes and the substrate that the enzyme acts upon. (4 marks: 1 mark each for enzyme; 1 mark each for substrate) Structure X: Enzyme: Substrate: Structure Y: Enzyme: Substrate: - 29 - OVER

6. Describe how the structure of each of the following aids in its function. (3 marks) Artery: Semi-lunar valve: Capillary: 7. Identify three substances transported by hemoglobin in the blood and give the name of each form of hemoglobin. (3 marks: 1 2 mark each) SUBSTANCE TRANSPORTED FORM OF HEMOGLOBIN - 30 -

Use the following diagram to answer question 8. X Y 8. Describe, in correct order, the events that occur during the transmission of a nerve impulse from point X to point Y. (8 marks) - 31 - OVER

Use the following diagram to answer question 9. X Y W Z 9. Identify the following structures and give a different function of each structure. (8 marks: 1 mark each for name; 1 mark each for function) Structure W: Name: Function: Structure X: Name: Function: - 32 -

Structure Y: Name: Function: Structure Z: Name: Function: - 33 - OVER

10. a) Give two functions of each of the following hormones. Estrogen: (2 marks) i) ii) LH (luteinizing hormone): (2 marks) i) ii) b) Describe two hormonal changes that occur in the mother as a result of implantation. (2 marks) i) ii) END OF EXAMINATION - 34 -

INSERT STUDENT I.D. NUMBER (PEN) STICKER IN THIS SPACE BIOLOGY 12 August 1999 Course Code = BI

FOR OFFICE USE ONLY BIOLOGY 12 August 1999 Course Code = BI Score for Question 1: 1. (4) Score for Question 2: 2. (3) Score for Question 3: 3. (4) Score for Question 8: 8. (8) Score for Question 9: 9. (8) Score for Question 10: 10. (6) Score for Question 4: 4. (5) Score for Question 5: 5. (6) Score for Question 6: 6. (3) Score for Question 7: 7. (3)