Emergency Poultry Disease Response Certificate Course

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The 9 th annual Emergency Poultry Disease Response certificate course will be offered by the University of Delaware to participants from around the world in 2017. Up to 22 participants will share their experiences and learn the latest information on avian influenza and its control during the five-day course. Topics will include understanding the influenza virus, surveillance, biosecurity, outbreak response and control, incident command structures, depopulation, disposal, composting, and decontamination. The course presents the Delaware Model, which emphasizes close cooperation between government, industry and educational institutions to successfully manage and control avian influenza outbreaks utilizing best management practices and technologies. Hands-on practical training exercises are a key feature of the course. Participants will earn continuing education units (CEU) necessary for veterinary or veterinary technician continuing education requirements: 3.2 CEUs (32 training hours) Dates: June 12 16, 2017 Location: Charles C. Allen, Jr. Biotechnology Laboratory, University of Delaware, Course Objectives: 1. Trainees will understand the elements of successfully planning for and responding to a poultry disease outbreak, including state/regional and national policies, dealing with live bird markets/backyard flocks, incident command management structures, surveillance of wild birds and commercial poultry and multi-jurisdictional cooperation. 2. Trainees will understand the personnel requirements to successfully respond to poultry disease outbreaks. 3. Trainees will understand the Personal Protective Equipment (PPE) requirements for personnel responding to an outbreak. 4. Trainees will understand the options available to cull sick flocks (CO2, foam, etc.). 5. Trainees will understand the options to dispose of culled flocks including inhouse composting. 6. Trainees will learn the key characteristics of a disinfection strategy and techniques to clean and disinfect poultry houses and equipment. Schedule:

Day 1: Monday, June 12, 2017 Topic Instructor Time (hours) Introduction Eric Benson, Robert Alphin and 08:00 08:15 Soma Chakrabarti Avian Influenza Basics Jack Gelb 08:15 09:00 Break 09:00 9:15 HPAIV and LPAIV - The current world Erica Spackman 09:15 10:05 situation US HPAI Disaster Response 2015 - Jonathan Zack/Fidelis Hegngi 10:05 10:55 2016 Break 10:55 11:10 Surveillance in Wild Birds and Poultry Brian Ladman 11:10 12:00 Welcome & Participants Introduction US Senator Chris Coons 12:00 12:45 Lunch 12:45 01:15 USDA Prospective Jack Shere, U.S. Chief 01:15 1:45 Veterinary Officer Break 01:45 02:00 AI Vaccination as a Control Measure Erica Spackman 02:00 02:45 Personal Protective Equipment Krista Murray 02:45 03:30 Break 03:30 03:45 PPE & Biosecurity Procedures for Proper AI Surveillance Swab Collection Surveillance Swabbing-Hands On Demonstration Robert Alphin 03:45 04:30 Student Interns 04:30 05:15 Day 2: Tuesday, June 13, 2017 Zoonotic & Foreign Animal Diseases: Robin King 08:30 09:20 One Health Concept Break 09:20 09:30 One Health Concept and the Human Health Side of AI Outbreaks US Poultry Industry Diane McGinnis-Hainsworth 09:30 10:20 Georgie Cartanza and Jon Moyle 10:20 11:10

Break 11:10 11:20 The US Live Bird Market System Aliza Simeone 11:20 12:10 Lunch 12:10 12:40 International Backyard Flocks and Live Jarra Jagne 12:40 01:30 Bird Markets* Picture Exchange: Participants local Participants 01:30 01:50 live bird markets Break 01:50 02:00 Biosecurity: A Day to Day Tool: Risk Robert Alphin 02:00 02:50 Assessment Biosecurity: A Response Tool Eric Benson 02:50 03:40 Break 03:40 03:50 Application of Incident Command Systems to Poultry Disease Outbreaks Certification Quiz 1: Introduction through Biosecurity Eric Benson 03:50 04:40 04:40 05:00 Day 3: Wednesday, June 14, 2017 Depart Newark, DE for tour of Delmarva Broiler Industry Robert Alphin and Dan Hougentogler 07:30 Visit commercial hatchery 9:30 10:30 Visit commercial broiler farm 10:30 12:00 Lunch at Georgia House, Millsboro, Michael Scuse, Secretary, 12:15 01:30 DE Delaware Depart. of Ag. Visit processing plant 01:45 03:00 Visit and dinner in Rehoboth, DE 04:00 06:30 (participant purchased dinner) Arrive back in Newark, DE 08:00 Day 4: Thursday, June 15, 2017 Guidelines, Methods and Criteria for Robert Alphin 08:30 09:30 Depopulation Break 09:30 09:40

Whole house and partial house CO2 Pamela Kuipers 09:40 10:30 gassing Break 10:30 10:40 Foam Depopulation Eric Benson 10:40 11:50 Lunch 11:50 12:20 Lessons Learned in Implementing Kofi Kwansah-Filson 12:20 01:00 EPDR Internationally (Web based from Ghana) Industry Lessons Learned in Recent Dan Hougentogler 01:00 01:50 HPAIV Outbreaks Break 01:50 02:00 Depopulation Demonstration 02:00 03:20 Surveillance, Preparedness and Fidelis Hegngi 03:20 04:10 Indemnification Building Capacity: Strengthening Erin Sorrell 04:10 05:00 Health Systems and Capacity Dinner (program provided) 06:30 08:00 Day 4: Friday, June 16, 2017 The University of Delaware and You Dean Mark Rieger 08:30 09:00 Break 09:00 09:10 Disposal Options Eric Benson 09:10 10:00 Break 10:00 10:10 Implementing Composting Robert Alphin 10:10 11:00 Break 11:00 11:10 Composting Lessons Learned from Edward Malek 11:10 12:00 Current US Outbreak Lunch 12:00 12:30 Cleaning and Disinfection Jeff Odle 12:30 01:20 Break 01:20 01:30

Composting Demonstration 01:30 03:00 Break 03:00 03:10 Certification Quiz 2: Depopulation 03:10 03:25 through Disinfection Wrap up 03:25 04:30 Module Descriptions: Influenza Viruses and Detection: What is the Avian bird flu? What are hemagglutinin and neuraminidase, and what do they do? How are new influenza subtypes created? How can influenza viruses be detected? HPAIV and LPAIV - The current world situation: An overview of the recent history of HPAIV and LPAIV avian influenza outbreaks in poultry and wild birds around the globe. US HPAI Disaster Response 2015-2016: A review of emergency poultry disease response to recent HPAI avian influenza outbreaks in the United States in 2015 and 2016. Surveillance in Poultry and Wild Birds: A critical step in emergency poultry disease preparedness and response involves wild bird and commercial poultry surveillance programs. These programs involve the testing of migratory birds nationally and internationally including the USDA, DOI and its cooperators (including the State of Delaware and the University of Delaware). In January 2006, the U.S. commercial poultry industry initiated an avian influenza testing program. All broiler flocks from participating companies, including all broiler companies on the Delmarva Peninsula, are tested and confirmed AI negative before going to slaughter. USDA Animal and Plant Health Inspection Service (APHIS) Prospective: Most of the participants for this year s EPDR course are supported through the efforts of USDA APHIS. Participants will have the opportunity to learn more about the role and programs of USDA APHIS. Avian Influenza Vaccination as a Control Measure: What AI vaccines are currently available and what are the results of recent AI vaccination studies. What are the implications of using a vaccination program on exports and disease control? Why vaccination is not currently used in the US. Personnel Protective Equipment: What types of personal protective equipment (PPE) are required during an outbreak response? The use and appropriateness of N95 masks, powered air purifying respirators and self-contained breathing apparatus will be discussed.

PPE and Biosecurity Procedures for Proper AI Surveillance Swab Collection: What types of personal protective equipment (PPE) and biosecurity procedures are required to collect surveillance field samples properly? Proper Surveillance Swabbing-Hands-On: Demonstration and participation in proper collection of field samples and the use of personal protective equipment. Zoonotic & Foreign Animal Diseases One Health Concept: Why do existing and emerging zoonotic and foreign animal diseases represent a continuing threat to national and international agriculture, human health, and national security? How the confluence of veterinary and human health should require the One Medicine Concept approach to dealing with the problem. One Health Concept and the Human Health Side of AI Outbreaks: Certain avian influenza viruses are zoonotic causing human infections and death. This is an example of when human health must be protected during a response and on a larger perspective for human populations in general requiring the One Health Concept. Overview of US Industry: An introduction to the US poultry industry will be presented including discussion of methods of commercial table egg and meat production. East Coast Live Bird Market System: The East Coast of the United States has a number of regional live bird markets which are managed differently than the larger integrated commercial poultry industry. These differences can pose biosecurity challenges. Strategies to deal with the challenges of the US live bird market system will be discussed. International Backyard flocks and Live Bird Market Systems: Live bird markets and village/backyard flocks present a unique challenge for both developed and developing nations. Backyard flocks and live bird market systems in countries in Africa and Asia will be discussed. This will include specific programs in Nigeria and Bangladesh geared towards biosecurity in farms and markets and how these programs can be used to reduce the risk of AI transmission. The module will also discuss the new trend of raising backyard poultry in the US and the risk it poses to the US poultry industry. Case reports will be used to illustrate the risks. Picture Exchange: Participants local live bird markets: This is an opportunity for participants to share pictures of their home country s live bird markets, backyard flocks and share comments of the challenges on dealing with avian influenza outbreaks in these situations. Biosecurity-A Day to Day Tool: Risk Assessment: Biosecurity is one of the principle steps in preventing the spread of disease. Biosecurity is the one aspect of avian influenza control that can be practiced on a daily basis. Examples of current methods, including risk assessment biosecurity programs will be discussed.

Biosecurity: A Response Tool: How do biosecurity procedures change during and outbreak. What is the purpose of the quarantine process and how is the process implemented and how are biosecurity procedures affected? Application of Incident Command Systems (ICS) to Poultry Emergencies: ICS is a scalable framework designed for emergency response. ICS can be used for emergencies such as fire protection to poultry diseases response. The system provides the framework for people from multiple agencies to work together. The same framework can be used for disease response, structural incidents, and similar. Tour of the Delmarva Broiler Industry: This is a bus tour to include visiting a commercial hatchery, broiler (meat) farm and processing plant. The tour will be followed by a visit to Rehoboth Beach located on the Atlantic Ocean for dinner and shopping. Guidelines, Methods and Criteria for Depopulation: There are a limited number of mass emergency depopulation procedures. Guidelines from the US Department of Agriculture, American Veterinary Medical Association, OIE, and others guide the selection of appropriate depopulation techniques. The advantages and disadvantages of several gas depopulation techniques will be discussed. Whole House and Partial House CO2 Gassing: Learn what equipment and supplies are required to use CO2 gas to depopulate table-egg layer and floor reared broiler or turkey houses. Learn what gassing and safety procedures need to be followed. How can you monitor carbon dioxide levels in the house? Foam Depopulation: Foam depopulation was developed as a fast, humane, and easy method to implement mass emergency depopulation. The procedure reduces the number of people required and can rapidly depopulate floor reared poultry. Participants will learn the characteristics of foam, the science behind the procedure, and how to implement foam depopulation. Lessons Learned in Implementing EPDR Internationally: Web based presentation from previous EPDR participant from Ghana who has implemented principles and procedures learned in the EPDR program in his home country. Lessons Learned from Recent US HPAI Outbreaks: The US has dealt with several HPAI outbreaks involving turkeys and chickens in the last few years. Foam depopulation was the primary method used for depopulation of floor reared poultry during recent US outbreaks. What were some of the challenges in being deployed to this outbreak and using this depopulation method during these outbreak? Depopulation Demonstration: Different water based foam depopulation methods will be demonstrated. Depending on time and conditions, participants will have the opportunity to operate the equipment.

USDA Surveillance, Preparedness and Indemnification: What are the current USDA surveillance, preparedness and indemnification programs and how do they operate? Building Capacity-Strengthening Health Systems and Capacity: What are the elements required to support and strengthen health systems and laboratory capacity building for disease detection, reporting, risk assessment, and response? Disposal Options: After catastrophic poultry emergencies, such as avian influenza and heat stress, disposing of large numbers of birds is necessary. One of the critical concerns in selecting a disposal method is biosecurity. Depending on the circumstances, the options may be limited. The advantages and disadvantages of several disposal options including on-farm burial, landfilling, incineration, and composting are reviewed. Implementing Composting: Composting is an effective on-farm means of inactivating avian influenza virus. Composting is suitable for international and domestic carcass disposal. Composting has been used for both daily and catastrophic mortality disposal. Daily mortality disposal has been successfully used on Delmarva since the 1980 s, while in-house composting is slightly newer. Procedures for both daily and catastrophic mortality are reviewed, including the mix & pile and layering techniques. Composting Lesson Learned from Recent AI Outbreaks: The current avian influenza outbreak in the US has impacted different sectors of the poultry industry including turkeys, caged layers and broilers. These sectors have different housing and production methods that impact emergency response including depopulation and disposal. Composting methods that were used in the recent outbreaks along with lessons learned will be discussed. Cleaning and Disinfection: How are disinfectants classified? What are the advantages and disadvantages of these different classes of disinfectants? What is different about the newer generation of disinfectants? What is the impact of organic material on the efficacy of these agents? What are the key characteristics of a disinfection strategy? Which chemicals should be used and how should they be applied? What consideration should be given to disinfecting equipment? Composting Demonstration: Both daily and catastrophic composing will be demonstrated.

Instructors: Robert L. Alphin, Jr., M.S. Senior Instructor & Allen Laboratory Manager Department of Animal and Food Sciences 107 Charles C. Allen Biotechnology Laboratory ralphin@udel.edu 302-831-0825 Eric R. Benson, Ph.D., M.S. Professor Animal and Food Science Department 242 Townsend Hall ebenson@udel.edu 302-275-2131 Georgie Cartanza Extension Agent II Carvel Research and Education Center Georgetown, DE 19947 cartanza@udel.edu Jack Gelb, Jr., Ph.D. Professor and Avian Biosciences Center Director Department of Animal and Food Sciences 034 Townsend Hall jgelb@udel.edu Fidelis N. Hegngi, D.V.M, M.S. Senior Staff Veterinarian Avian Health Avian, Swine and Aquatic Animal Health Center Surveillance, Preparedness and Response Services USDA, APHIS, Veterinary Services 4700 River Road, Unit 46, 4B-04.2 Riverdale, MD 20737-1231 fidelis.n.hegngi@aphis.usda.gov

Dan Hougentogler, B.S. Research Associate II 202A O.A. Newton Poultry Building dhoug@udel.edu Jarra F. Jagne, D.V.M., ACPV Senior Extension Associate Veterinary Support Services Cornell University Animal Health Diagnostic Center 113 Burleigh Drive, Ithaca, NY 14850 Jj34@cornell.edu Robin King, D.V.M. Food Protection Program Manager US Army Institute of Public Health, Retired quilpie21@gmail.com Pamela Kuipers, B.Sc. (Agr) Project Manager Egg Farmers of Ontario 7195 Millcreek Drive Mississauga, ON L5N 4H1 pamk@getcracking.ca A. H. Kofi Kwansah-Filson, D.V.M., MSc.Vet Regional Veterinary Officer, Retired Veterinary Services Directorate Bungalow Number 3, Old Berwai Road, Nhyiaeso Kumasi, Ghana kwanfilson@gmail.com Brian S. Ladman, Ph.D., M.S., M.B.A. Associate Scientist Department of Animal and Food Sciences 109 Allen Laboratory bladman@udel.edu

Edward Malek, B.Sc. National Operations Specialist Canadian Food Inspection Agency Government of Canada Ontario, Canada edward.malek@inspection.gc.ca Jonathan Moyle, Ph.D. Poultry Specialist Cooperative Extension Service University of Maryland Lower Eastern Shore Research and Education Center 27664 Nanticoke Road Salisbury, MD 21801 jmoyle@umd.edu Krista Murray, M.S., RBP, CBSP Assistant Director Environmental Health & Safety 132 General Services Building klmurray@udel.edu Jeff Odle Technical Sales Manager Disinfection US & Canada LANXESS 200 Powder Mill Road, Building 402 Wilmington, DE 19803 Jeffrey.Odle@lanxess.com Jack Shere, D.V.M., M.S.Ed. U.S. Chief Veterinary Officer USDA, APHIS, Veterinary Services Washington D.C. Aliza Simeone, D.V.M. Veterinarian Pennsylvania Department of Agriculture 1015 Bridge Road Collegeville, PA 19426 asimeone@state.pa.us

Erin Sorrell, Ph.D., M.S. Assistant Professor Department of Microbiology Center for Global Health Science and Security NW 306, Medical-Dental Building 3900 Reservoir Road Georgetown University N.W., Washington D.C. 20007 Erin.Sorrell@georgetown.edu Erica Spackman, Ph.D., M.S. Research Microbiologist Exotic and Emerging Avian Viral Diseases Unit, SEPRL US Dept. of Agriculture, Agricultural Research Service 934 College Station Rd. Athens, GA 30605 Erica.Spackman@ars.usda.gov Jonathan Zack, D.V. M. Director of Preparedness and Incident Coordination USDA APHIS, Veterinary Services 4700 River Road, Unit 41 Riverdale, MD 20737 jonathan.t.zack@aphis.usda.gov Other Activities: There will be an optional tour of the University of Delaware on Saturday, June 11. Please be present in the hotel lobby at 10:00 am to participate. Lunch will be provided at the end of the tour. Other Instructions The program cost includes lodging and limited meals (breaks and lunches, dinner on Thursday) for the participants during the program. Dress for the program is casual / corporate casual. Participants are encouraged to bring shoes that they can wear during equipment demonstrations in a farm environment. Acknowledgements: Funding for the Emergency Poultry Disease Certificate course in over the last nine years has been provided by USDA APHIS. Funding for the initial development of the Emergency Poultry Disease Certificate course was provided by the USDA Avian Influenza Combined Agriculture Project titled Prevention and Control of Avian Influenza in the U.S. (AICAP 2).

Website: Additional information can be found at the website: http://canr.udel.edu/avianbiosciences/