12th & 13th May 2016 Weston Education Centre, Kings College Hospital London

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EUROSON SCHOOL CEUS Course How to Incorporate CEUS into your Imaging Practice 12th & 13th Weston Education Centre, Kings College Hospital London CPD points for two days: EFSUMB 16 CME points BMUS 12 CPD points RCR 12 CPD points BMUS THE BRITISH MEDICAL ULTRASOUN Course fees: Standard fee - 400 Trainees & Sonographers - 320 EFSUMB & BMUS members - 360 To register visit: www.bmus.org

12th 09.20-09.30 Welcome Liver and Vascular Session - Prof. Paul Sidhu A welcome and short introduction over coffee and pastries with an overview of the programme. The 2-day programme will be reviewed and social events detailed. 09.30-10.00 Introduction to CEUS - Prof. Martin Krix Technical and clinical basis o CEUS for application in daily practice. Prof. Martin Krix, Bracco Imaging, Konstanz, 10.00-10.20 EFSUMB CEUS Liver Guidelines - Prof. David Cosgrove The evolving CEUS Guidelines are introduced with the mechanism of production explained, in particular the enormous effort that goes into producing these guidelines by a large group of experts. 10.20-10.40 Malignant Focal Liver Lesions - Dr. Hans-Peter Weskott Malignant focal liver lesions: B-mode, colour Doppler imaging and contrast enhanced ultrasound criteria, typical cases will be presented. 10.40-11.00 Hepatocellular Carcinoma: Current Imaging Guidelines - Prof. Fabio Piscaglia Ultrasonography is the recommended method of surveillance in patients with cirrhosis for early diagnosis of hepatocellular carcinoma (HCC), occuring in 2-5% per year. CEUS is able to display the internal vascularization of any nodules, leading to the ability to establish a diagnosis of HCC, achievable in the same patient session. Moreover, when the conclusive typical findings of HCC are not present, CEUS has superb ability to suggest that a nodule is benign or malignant. The lecture will illustrate how to correctly interpret CEUS information for focal lesion in cirrhosis. 11.00-11.20 Break 11.20-11.50 Benign Focal Liver Lesions - Dr. Hans-Peter Weskott Benign focal liver lesions: B-mode, colour Doppler imaging and contrast ehanced ultrasound CEUS criteria, typical cases will be presented. 11.50-12.20 Potential Conundrums of Hypervascular Lesions - Prof. Adrian Lim The potential pitfalls in characterising the hypervascular lesion, particularly in patients with a background of known malignancy or significant chronic liver disease will be discussed. 12.20-12.40 Imaging Management of Incidental Focal Liver Lesions - Dr. Suzanne Ryan The evaluation of the focal liver lesion, both benign and malignant will be discussed, with particular emphasis on the problem solving imaging technique. Prof. David Cosgrove Professor of Clinical Ultrasound, Imperial College London & King s College Hospital, Dr. Hans-Peter Weskott Central Ultrasound Dept Klinikum Region Hannover, Klinikum Siloah, Hannover, Prof. Fabio Piscaglia Unit of Internal Medicine, Department of Medical & Surgical Sciences, University of Bologna, Itlay Prof. Adrian Lim Adjunct Professor of Imaging, Charing Cross Hospital, Imperial College Dr. Suzanne Ryan Consultant Hepatobiliary Hospital,

12th 12.40-14.00 Lunch 14.00-14.20 NICE guidelines on CEUS Liver - Dr James Pilcher The National Institute for Health and Clinical Excellence (NICE) have issued two sets of guidelines on the use of CEUS in liver lesions; the clinical usefulness and position in the imaging pathway, and also implementation advice. 14.20-14.40 Liver Transplantation - Prof. Paul Sidhu The role of CEUS in the pre- and post-transplant patient will be discussed with emphasis on vascular complications. 14.40-15.00 Liver abscesses and collections - Dr Gibran Tim Yusuf The ultrasound diagnosis of an abscess may be difficult with varying B-mode appearances; CEUS clearly demonstrates the liquid centre. Additionally intra-cavity CEUS plays a role in the assessment of the interna architecture of an abscess. 15.00-15.20 Gallbladder and Biliary Disease - Dr Hans-Peter Weskott Inflammatory changes of the gallbladder wall, benign and malignant tumors, contrast enhanced ultrasound in bile duct pathology. 15.20-15.40 Quantitative Measurement: Techniques and Challenges - Dr Robert Eckersley A discussion of the potential and limitations of contrast enhanced ultrasound imaging for quantitative measurement of blood flow. Particular attention will be paid to practical approaches and the avoidance of common pitfalls. 15.40-16.00 Break 16.00-16.30 Aorta and EVAR - Prof. Dirk-Andre Clevert CEUS plays an important role in the assessment of aortic disease particular in the detection of complications following EVAR procedures. 16.30-17.00 Carotid Disease - Prof. Dirk-Andre Clevert The early usefulness of CEUS in the assessment of vessel narrowing has been documented, with further advances in plaque neo-vascularization stratifying risk factors. Dr. James Pilcher Consultant Radiologist, St George s Hospital Dr. Gibran Tim Yusuf Senior Radiology Fellow Kings College Hospital, London, Dr. Hans-Peter Weskott Central Ultrasound Dept Klinikum Region Hannover, Klinikum Siloah, Hannover, Dr. Robert Eckersley Senior Lecturer in Biomedical Engineering at King s College London Prof. Dirk-Andre Clevert Institut fu r Klinische Radiologie, Ludwig Maximilian Universitaẗ Klinikum der Universitaẗ Mu nchen, 17.00-17.30 Interesting Cases: an interactive quiz - Whole faculty 19.30-22.30 Course Dinner

13th 09.00-09.20 Registration and Welcome & Non-hepatic session - Prof. Paul Sidhu 09.20-09.40 CEUS Non-Liver Guidelines - Dr Vito Cantisani EFSUMB guidelines and recommendations on CEUS non-liver applications; the many areas where the usefulness has been pioneered by European based researchers. 09. 40-10.00 Legal aspects: using CEUS off license - Prof Paul Sidhu This lecture will demonstrate the standing in legal terms for the use of medicines off label in the adult population, with extrapolation to the child. Evidence based findings, regulatory view, and the legal aspect will be discussed. Dr. Vito Cantisani Department of Radiological Sciences Oncology and Pathology, Policlinico Umberto I, University Sapienza, Rome, Italy 10.00-10.20 Renal disease: technique and quantification - Dr Konrad Friedrich Stock How to perform CEUS of the kidney and how to quanitfy and document kidney perfusion. 10.20-10.50 Renal Disease: solid and cystic lesions - Dr Christopher Harvey Contrast-enhanced US can accurately characterise indeterminate renal lesions, solid lesions, complex cysts and focal inflammatory lesions with no nephrotoxicity. CEUS is excellent for assessing the microcirculation of kidneys. 10.50-11.10 Renal Disease: transplantation - Dr Konrad Friedrich Stock Different fields of CEUS-application for kidney transplants as applied directly to clinical practice. 11.10-11.30 Break Dr. Konrad Friedrich Stock Internist, Consultant, Ultrasound Section, Dept of Nephrology, Klinikum rechts der lsar der Technischen Universitat, Dr. Christopher Harvey Consultant Radiologist, Hammersmith Hospital, Imperial College 11.30-12.00 Pancreas: Tumour and inflammation - Prof. Mirko D Onofrio CEUS can improve the diagnosis of pancreatic diseases during the ultrasound study. CEUS can characterize pancreatic neplasms immediately after the detection during the ultrasound examination allowing a better management of pancreatic tumors. Prof. Mirko D Onofrio Institute of Radiology, GB Rossi Hospital University of Verona, Verona, Italy 12.00-12.30 Salivary Glands and Thyroid - Dr Vito Cantisani Current update knowledge, limitations and perspectives on CEUS for salivary, parathyroid and thyroid lesion characterisation. 12.30-12.50 Testis: Tumours and Inflammation - Dr Dean Huang To illustrate the usefulness of CEUS in improving diagnostic confidence for testicular pathology, in particular in the context of characterising vascularity and confirming benignity. Dr. Dean Huang Consultant Interventional Hospital,

13th 13.10-14.20 Lunch 14.20-14.50 CEUS in Paediatric Blunt Abdominal Trauma - Dr Annamaria Deganello The use of CEUS in blunt abdominal trauma in children is detailed, with the position of CEUS in relation to CT of the abdomen highlighted with the reduction in radiation paramount in our practice. 14..50-15.20 CEUS in the Paediatric Liver: A Problem Solving Tool - Dr Maria Sellars Our extensive experience of assessing and characterising incidental focal liver lesions in children. The position of CEUS in the imaging pathway is discussed. 15.20-15.40 Break 15.40-16.00 Miscellaneous application in paediatric practice - Dr Annamaria Deganello A tour of the areas where improvisation and lateral thinking allows a radiation free diagnostic procedure in the child. Dr. Annamaria Deganello Consultant Paediatric Hepatobiliary Radiologist, King s College Hospital, London, Dr. Maria Sellars Consultant Paediatric Hepatobiliary Radiologist, Kings College Hospital, London Dr. Keshthra Satchithananda Consultant Radiology and Director of Breast Screening, King s College Hospital, 16.00-16.20 Sentinel node detection in breast malignancy - Dr Keshthra Satchithananda The role of CEUS in identifying the sentinel axillary node in primary breast cancer and its place in the multidisciplinary management and decision making in the treatment of breast cancer. 16.20-16.50 Intervention using CEUS - Dr Dean Huang This will provide an illustration of a spectrum of routinely performed US-guided procedures where the innovative use of CEUS could be rewarding. Dr. Dean Huang Consultant Interventional Hospital, 16.50-17.00 Course assessment & course closes