Citation for published version (APA): Romanos, J. (2011). Genetics of celiac disease and its diagnostic value. Groningen: s.n.
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1 University of Groningen Genetics of celiac disease and its diagnostic value Romanos, Jihane IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2011 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Romanos, J. (2011). Genetics of celiac disease and its diagnostic value. Groningen: s.n. Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date:
2 CURRICULUM VITAE C.V. JIHANE ROMANOS
3 206 Curriculum Vitae Jihane Romanos was born on 23 rd January 1982 in Haret-Sakhr, Lebanon. She lived in Sao Paulo, Brazil, for two years before moving back to Lebanon where she grew up and went to school at the Soeur des Saint Coeur college in Kfarhbab. After taking the French baccalaureate in 2000, she went to the American University of Beirut where she majored in Biology (BSc). In 2003 Jihane moved back to Brazil, where she followed a three-month training course at the genetics department of the University of Sao Paulo. In 2004, she started her MSc degree in that department, working on the screening of mutations in the OTOF gene in patients with hearing impairment and its relation with auditory neuropathy, under the supervision of Prof. Regina Celia Mingronino-Netto, PhD. She graduated in 2006 with an MSc in Biology, specializing in genetics. In 2007, she started her PhD work at the Department of Genetics, University Medical Center Groningen, the Netherlands, under the supervision of Prof. Cisca Wijmenga, PhD. Her main topic has been the genetics of celiac disease and assessing its diagnostic value. As someone holding both the Brazilian and Lebanese nationalities, Jihane has excellent language skills. She is fluent in Arabic, French, English and Portuguese, and has also learned some basic Dutch.
4 207 Publications (H-index in Sept 2011 = 8) *Both authors contributed equally to the manuscript 1. Trynka G, Hunt KA, Bockett NA, Romanos J, Mistry V, Szperl A, Bakker SF, Bardella MT, Bhaw- Rosun L, Castillejo G, de la Concha EG, Almeida RC, Dias KM, van Diemen CC, Dubois PCA, Duerr RH, Edkins S, Franke L, Fransen K, Gutierrez J, Heap GAR, Hrdlickova B, Hunt S, Plaza Izurieta L, Izzo V, Joosten LAB, Langford C, Mazzilli MC, Mein CA, Midah V, Mitrovic M, Mora B, Morelli M, Nutland S, Núñez C, Onengut-Gumuscu S, Pearce K, Platteel M, Polanco I, Potter S, Ribes-Koninckx C, Ricaño-Ponce I, Rich SS, Rybak A, Santiago JL, Senapati S, Sood A, Szajewska H, Troncone R, Varadé J, Wallace C, Wolters VM, Zhernakova A, CEGEC (Spanish Consortium on the Genetics of Coeliac Disease), PreventCD Study Group, Wellcome Trust Case Control Consortium, Thelma B.K., Cukrowska B, Urcelay E, Bilbao JR, Mearin ML, Barisani D, Barrett JC, Plagnol V, Deloukas P, Wijmenga C, van Heel DA. Dense genotyping reveals and localises multiple common and rare variant association signals in celiac disease. Nat. Genet. 2011; in press 2. Sperandeo MP, Tosco A, Izzo V, Tucci F, Troncone R, Auricchio R, Romanos J, Trynka G, Auricchio S, Jabri B, Greco L. Potential celiac patients: a model of celiac disease pathogenesis. PLoS One. 2011; 6(7):e Zhernakova A, Stahl EA, Trynka G, Raychaudhuri S, Festen EA, Franke L, Westra HJ, Fehrmann RS, Kurreeman FA, Thomson B, Gupta N, Romanos J, McManus R, Ryan AW, Turner G, Brouwer E, Posthumus MD, Remmers EF, Tucci F, Toes R, Grandone E, Mazzilli MC, Rybak A, Cukrowska B, Coenen MJ, Radstake TR, van Riel PL, Li Y, de Bakker PI, Gregersen PK, Worthington J, Siminovitch KA, Klareskog L, Huizinga TW, Wijmenga C, Plenge RM. Metaanalysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-hla shared loci. PLoS Genet. 2011; 7(2):e Romanos J and Wijmenga C. Predicting susceptibility to celiac disease by genetic risk profiling. Annals of Gastroenterology and Hepatology. 2010; 1(1): Hogen Esch CE, Rosén A, Auricchio R, Romanos J, Chmielewska A, Putter H, Ivarsson A, Szajewska H, Koning F, Wijmenga C, Troncone R, Mearin ML. The PreventCD Study design: towards new strategies for the prevention of coeliac disease. Eur J Gastroenterol Hepatol. 2010; 22(12):
5 Zhernakova A, Elbers CC, Ferwerda B, Romanos J, Trynka G, Dubois PC, de Kovel CG, Franke L, Oosting M, Barisani D, Bardella MT; Finnish Celiac Disease Study Group, Joosten LA, Saavalainen P, van Heel DA, Catassi C, Netea MG, Wijmenga C. Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection. Am J Hum Genet. 2010; 86(6): Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek WH, Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA. Multiple common variants for celiac disease influencing immune gene expression. Nat Genet. 2010; 42(4): Romanos J*, van Diemen CC*, Nolte IM, Trynka G, Zhernakova A, Fu J, Bardella MT, Barisani D, McManus R, van Heel DA, Wijmenga C. Analysis of HLA and non-hla alleles can identify individuals at high risk for celiac disease. Gastroenterology 2009; 137(3):834-40, 840.e Romanos J, Kimura L, Fávero ML, Izarra FA, de Mello Auricchio MT, Batissoco AC, Lezirovitz K, Abreu-Silva RS, Mingroni-Netto RC. Novel OTOF mutations in Brazilian patients with auditory neuropathy. J. Hum. Genet. 2009; 54(7): Romanos J*, Koskinen L*, Kaukinen K, Mustalahti K, Korponay-Szabo K, Barisani D, Bardella M.T, Ziberna F, Vatta S, Széles G, Pocsai Z, Karell K, Haimila K, Ádány R, Not T, Ventura A, Mäki M, Partanen J, Wijmenga C, Saavalainen P. Cost-effective HLA-typing with tagging SNPs predicts celiac disease risk haplotypes in Finnish, Hungarian and Italian populations. Immunogenetics 2009; 61(4): Romanos J and Wijemenga C. Letter to the editor in response to the article Two single nucleotide polymorphisms identify highest-risk diabetes human leukocyte antigen genotype: potential for rapid screening by Barker et al. Diabetes 2009; 58(1):e1; author reply e Romanos J, Barisani D, Trynka G, Zhernakova A, Bardella MT, Wijmenga C. Six new celiac
6 209 disease loci replicated in an Italian population confirming association to celiac disease. J Med Genet. 2009; 46(1): Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-κB signalling. Gut 2009; 58(8): Monsuur AJ, de Bakker PI, Zhernakova A, Pinto D, Verduijn W, Romanos J, Auricchio R, Lopez A, van Heel DA, Crusius JB, Wijmenga C. Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms. PLoS One 2008; 28;3(5):e Hunt KA, Zhernakova A, Turner G, Heap GAR, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R, Takeuchi F, McLaren WM, Holmes GKT, Howdle PD, Walters JRF, Sanders DS, Playford RJ, Trynka G, Mulder CJJ, Mearin ML, Verbeek WHM, Trimble V, Stevens FM, O Morain C, Kennedy NP, Kelleher D, Pennington DJ, Strachan DP, McArdle WL, Mein CA, Wapenaar MC, Deloukas P, McGinnis R, McManus R, Wijmenga C, van Heel DA. Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genetics 2008; 40: Romanos J*, Rybak A*, Wijmenga C, Wapenaar MC. Molecular diagnosis of celiac disease: Are we there yet? Expert Opin. Med. Diagn. 2008; 2(4): Abreu-Silva RS, Batissoco AC, Lezirovitz K, Romanos J, Rincon D, Auricchio MT, Otto PA, Mingroni-Netto RC. Correspondence regarding Ballana et al., Mitochondrial 12S rrna gene mutations affect RNA secondary structure and lead to variable penetrance in hearing impairment. Biochem Biophys Res Commun. 2006; 343(3): Fávero ML, Romanos J, Mingroni-Netto RC, Balieiro CR, Donini TS, Spinelli M. Auditory neuropathy due to mutations in OTOF gene. Arq. Otorrinolaringol. 2005; 9(4): Viana-Morgante AM (The Human Cytogenetics Study Group including Romanos J). The ratio of maternal to paternal UPD associated with recessive diseases. Hum Genet. 2005; 117(2-3):
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