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1 Note: Page numbers of article titles are in boldface type. A ACCORD (Action to Control Cardiovascular Risk in Diabetes), 20 Action in Diabetes and Vascular Disease (ADVANCE), 20 Action to Control Cardiovascular Risk in Diabetes (ACCORD), 20 ADVANCE (Action in Diabetes and Vascular Disease), 20 Advancement flaps, Amputations. See also Partial foot amputations. prostheses for, Angiosomes, in revascularization, 22 Ankle-brachial index, in peripheral vascular disease, Ankle-foot orthosis, Antibiotics for Charcot neuroarthropathy, for infections, 60, Antiplatelet therapy, for peripheral vascular disease, 21 Apligraf BAT, Aspirin, for peripheral vascular disease, 21 Atherectomy, for peripheral vascular disease, 23 Autonomic neuropathy, in Charcot neuroarthropathy, B BATs. See Bioengineered alternative tissues. Beta blockers, perioperative, 3, 7 Bilayer bioengineered alternative tissues, 92, Bilobed flaps, 137 Bioengineered alternative tissues, acellular, 92, 95 cellular, 92 future of, indications for, 90 principles of, risks of, 93 types of, Biopsy for Charcot neuroarthropathy, 156 for infections, 60, 62 Bisphosphonates, for Charcot neuroarthropathy, 157 Bone grafts, for Charcot neuroarthropathy, 161 Braces. See Offloading options. Clin Podiatr Med Surg 31 (2014) podiatric.theclinics.com /14/$ see front matter ª 2014 Elsevier Inc. All rights reserved.

2 188 C Callus, offloading options for, 73 CAPRIE (Clopidogel versus Aspirin in Patients at Risk of Ischemic Events) study, 21 Carbon copy foot, 181 Cardiac disease, perioperative management of, 2 3, 5, CARDS (Collaborative Atorvastatin Diabetes Study), Cast, total contact, 75, 83, 85, Cement, antibiotic-impregnated, for infections, Central ray or toe, amputation of, Charcot neuroarthropathy, classification of, complexity of, definition of, 152 deformity correction algorithm for, diagnosis of, , etiology of, history of, orthotic walker for, 83 prevalence of, 152 recurrence of, 157 treatment of, Chopart amputation, Chronic ischemic diabetic foot, cell therapies for, drugs for, incidence of, 28 pathophysiology of, 28 rheologic treatment for, Clopidogel versus Aspirin in Patients at Risk of Ischemic Events (CAPRIE) study, 21 Collaborative Atorvastatin Diabetes Study (CARDS), Computed tomography, 51 52, Computed tomography angiography, for peripheral vascular disease, Contraction, of skin grafts, C-reactive protein in infections, 59 in peripheral vascular disease, 13 Culture for Charcot neuroarthropathy, 156 for infections, 59, 62 Cultured epithelial autografts (epidermal bioengineered alternative tissues), Cushioning liners, of prosthesis, C-Walk foot, 181 Cytokines, in Charcot neuroarthropathy, D De Marco formula, for ischemic foot, 37 Debridement for infections, 60, of skin graft recipient bed, 140

3 189 Dermagraft, Dermal bioengineered alternative tissues, 92, Dermatome, for skin graft harvesting, 141 Diabetic foot and ankle amputations for, bioengineered tissues for, Charcot neuropathy of, 83, chronic ischemia in, infections of. See Infections and osteomyelitis. offloading of, pathology of, perioperative management of, 1 10 peripheral vascular disease and, prosthetic options for, soft tissue coverage for, Digital subtraction angiography, for peripheral vascular disease, 19 Doppler evaluation, for peripheral vascular disease, Double V-to-Y flaps, Dressing, for skin graft, 142 E Ectoskeletal shank, of prosthesis, 176 Eichenholtz stage, of Charcot neuroarthropathy, 157 Electrocardiography, perioperative, 3 Endoskeletal shank, of prosthesis, 176 Endovascular techniques, for peripheral vascular disease, Energy-returning feet, Epidermal bioengineered alternative tissues, Epidex, 94 Erythrocyte sedimentation rate, in infections, 59 Exostectomy, for Charcot neuroarthropathy, 160 External fixation, for Charcot neuroarthropathy, F Femoropopliteal bypass, Fifth ray, amputation of, First ray, amputation of, Fixation, for Charcot neuroarthropathy, Flaps, anatomy of, 129 complications of, decision ladder for, 127 for amputation coverage, patient health parameters and, physiology of, 130 principles of, 128 technique for, types of, Flex foot,

4 190 Fluid control knees, 177, 179 Friction-controlled knee, 177 G Glucose control, perioperative, 6 9, 20 GraftJacket, Granulocyte colony-stimulating factor, for ischemic foot, 36 H Hallux, amputation of, Healing, of skin grafts, , Heart Outcomes Prevention Evaluation (HOPE), 20 Heberprot-P, for ischemic foot, HELP (heparin-induced extracorporeal low-density lipoprotein precipitation), for ischemic foot, 38 Hematoma, in skin graft, 143 Heparin-induced extracorporeal low-density lipoprotein precipitation (HELP), for ischemic foot, 38 HOPE (Heart Outcomes Prevention Evaluation), 20 Human epidermal growth factor, for ischemic foot, Hydraulic (fluid control) knee, 177, 179 Hypertension, treatment of, 20 I ICECROSS liners, of prosthesis, Imaging, See also specific modalities. computed tomography, magnetic resonance imaging, radiography, 44, 50 radionuclide bone scans, single-photon emission computed tomography, ultrasonography, 44 Infections and osteomyelitis, anatomic considerations in, 61 diagnosis of, in Charcot neuroarthropathy, , in peripheral vascular disease, 15 in skin grafts, 143 nonoperative treatment of, outcomes of, 65 pathology of, 58 prevalence of, 57 recurrence of, 66 statistics on, 58 surgical treatment of, wound closure for, Inflammation, uncontrolled, in Charcot neuroarthropathy, Infrapopliteal percutaneous transluminal angioplasty, for peripheral vascular disease, Insulin, perioperative, 6 9

5 191 Insulin resistance, Integra, Intelligent (microprocessor) knee, 177, Intramedullary screws, for Charcot neuroarthropathy, 162 Ischemic diabetic foot. See Chronic ischemic diabetic foot. iwalk prosthetic foot, 182 K Kidney disease, perioperative management with, 3 5, 7 L Limberg flaps, Liners, of prosthesis, Lipoaspirate cell therapy, for ischemic foot, Lipo-prostaglandin, for ischemic foot, Lisfranc disarticulation, 123 Locking liners, of prosthesis, M Magnetic resonance imaging, for Charcot neuroarthropathy, for infections, Magnetic resonance imaging angiography, for peripheral vascular disease, 19 Manual locking knee, 177 Matristem, 96 Meshing, of skin graft, Metatarsophalangeal amputation, 183 Microprocessor foot, 182 Microprocessor knee, 177, Midfoot amputation, Midtarsal amputation, Multi-axis foot, 181 Muscle flaps, for infections, Myocardial infarction, perioperative, 3, 5 Myskin, 94 N Negative Pressure Wound Therapy, for skin graft, 142 Nephropathy, perioperative management with, 3 5, 7 Neuropathy, Charcot. See Charcot neuroarthropathy. Neurotraumatic theory, of Charcot neuroarthropathy, Neurovascular theory, of Charcot neuroarthropathy, Nitric oxide, in peripheral vascular disease, 13 Nonenergy-returning feet,

6 192 O Oasis BAT, 96 Offloading options, accommodative, 72 clinical correlation and, complications of, foot presentations and, for ideal foot, functional, 72 Oral hypoglycemic agents, perioperative, 6 Orcel BAT, 97 Organization phase, of skin graft healing, 139 Orthotics. See Offloading options. Osteomyelitis. See Infections and osteomyelitis. P Partial foot amputations, central ray, fifth ray, first ray, hallux, midfoot, options for, procedure for, protheses for, rearfoot, transmetatarsal, Patellar tendon-bearing sockets and modifications, of prosthesis, Pedal bypass grafts, Pedorthic strategies. See Offloading options. Perfusion tests, in peripheral vascular disease, 16 Perioperative management. See also specific procedures. assessment in, 2 glucose control in, 6 9, 20 history in, 4 in cardiac disease, 2 3 in kidney disease, 3 5, 7 Peripheral vascular disease, atypical presentations of, 14 epidemiology of, 12 imaging for, pathology of, patient history of, physical examination for, surgical options with, treatment of, PermaDerm, 98 Pie-crusting, of skin graft, Plantar plating, for Charcot neuroarthropathy, Plastizote, for orthotics, 78 80

7 193 Plate fixation, for Charcot neuroarthropathy, Pneumatic (fluid control) knee, 177, 179 Polycentric axis knee, 177, 179 Polyvinylpyrrolidone, in De Marco formula, 37 Porcine xenograft, 140 Positron emission tomography, for Charcot neuroarthropathy, Postoperative periods, offloading options for, Power knee, 177, 180 Preoperative period, offloading options for, PriMatrix, Probe-to-bone test, 15, 59 Procaine, in De Marco formula, 37 Processed lipoaspirate cell therapy, for ischemic foot, Proprio foot, 182 Prostaglandins, for ischemic foot, Prostheses, ankle-foot, below-knee, components of, history of, partial-foot, Pulse, in peripheral vascular disease, Pulse volume recordings, in peripheral vascular disease, 16 R Radiography, 44, 50, Radionuclide bone scans, 45 47, 59 RANKL, in Charcot neuroarthropathy, Rearfoot amputation, Recanalization, for peripheral vascular disease, 23 Revascularization for peripheral vascular disease, for skin graft healing, 138 Rheological treatment, for ischemic foot, 37 Rhomboid flaps, Rocker bottom shoes, Rotation flaps, S SACH foot, 180 Seal-in liners, of prosthesis, Seattle foot, 181 Serum imbibition, in skin graft healing, 138 Shanks, of prosthesis, 176 Shoes for partial amputations, therapeutic, 80 Silver sulfasdiazine, for skin graft recipient bed, 140 Single lobe flaps,

8 194 Single rotation flaps, Single-axis foot, 180 Single-axis knee, Single-photon emission computed tomography, 52 53, 60 Skin grafts, anatomy of, 129 application of, 142 complications of, contraction in, decision ladder for, 127 donor site harvesting of, 141 dressing for, 142 for infections, healing of, , indications for, 140 meshing, patient health parameters and, physiology of, pie-crusting of, postoperative care for, principles of, 128 recipient bed preparation for, thickness classification of, Sleeves, of prosthesis, Socket, of prosthesis, Soft tissue coverage, See also Flaps; Skin grafts. anatomy of, 129 bioengineered alternative tissues, decision ladder for, 127 patient health parameters and, principles of, 128 Stem cell transplantation autologous, for ischemic foot, for BAT, Stents, for peripheral vascular disease, 23 Stroke, perioperative, 3, 5 Subintimal recanalization, for peripheral vascular disease, 23 Suspension system, of prosthesis, 176 Syme amputation distal central ray, 112 distal hallux, T Tarsometatarsal joint amputation, 123, Theraskin, Tissuetech, Toe amputation, protheses for, Total contact cast, 75, 83, 85, Total surface-bearing socket, of prosthesis, 175 Transmetatarsal amputation, ,

9 195 Transposition flaps, Transtarsal amputation, Transtibial sockets, of prosthesis, U UKPDS (United Kingdom Prospective Diabetes Study), 20 Ulcer(s) examination of, in peripheral vascular disease, from orthosis, 87 infected. See Infections and osteomyelitis. offloading options for, Ultrasonography, 44 for infections, for peripheral vascular disease, United Kingdom Prospective Diabetes Study (UKPDS), 20 Urokinase, for ischemic foot, V VADT (Veterans Affairs Diabetes Trial), 20 Vascular examination, in peripheral vascular disease, Vascular failure, in skin graft, 143 Veterans Affairs Diabetes Trial (VADT), 20 V-to-Y flaps, 132 W Wound closure, bioengineered alternative tissues for,

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