Day 1: Saturday, November 10, Inauguration Day: Saturday, November 10, 2018
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1 The USERN 2018 Congress and Prize Awarding Festival + Post PID Course Day 1: Saturday, November 10, 2018 Inauguration Day: Saturday, November 10, :00 11:00 Visit to the Archeological Museum of Magna Graecia and Bronzi di Riace 10:00 11:00 Registration (Participants) 11:00 13:30 Opening Session 11:00 11:10 Italian National Anthem - USERN Introductory Clip 11:10 11:25 Welcome to Calabria by the Rector of the Università Mediterranea and by Institutional Representatives 11:25 11:35 Welcoming Speech by the ESGM President - Giovanni Romeo (IT) 11:35 11:55 Introductory Speech by the USERN Founding President - Nima Rezaei (IR) 11:55-12:25 Keynote Speech Science is Legality Marco Lombardo (IT) 12:25-12:45 Autism research at CNR-ISASI (Messina) - Giovanni Pioggia (IT) 12:45 13:30 Official Opening of the USERN Prize Festival in 5 Fields of Science on the occasion of the UNESCO World Science Day for Peace and Development Musical Intermissions of the Choir of the Università Mediterranea 13:30 14:30 Buffet lunch 14:30 14:50 Multidisciplinary Collaborations - Kathleen Sullivan (USA)
2 14:50 15:10 Talk by USERN Laureate in Social Sciences 15:10 15:30 How Gene Therapy Can Change Life of Sick Kids in the Future? - Alessandro Aiuti (IT) 15:30 15:50 Talk by USERN Laureate in Medical Sciences 15:50 16:10 The Role of Genetics in Health and Disease - Alessandro Plebani (IT) 16:10 16:30 Talk by USERN Laureate in Biological Sciences 16:30 16:50 Relevance of Genetic Studies in a Sardinian Isolated Population - Francesco Cucca (IT) 16:50 17:10 Talk by USERN Laureate in Physical Sciences 17:10 17:30 To Drive the Science toward Peace; with or without Humans? - Massimo Cappaccioli (IT) 17:30 17:50 Talk by USERN Laureate in Formal Sciences 18:00-20:00 Awarding the 12 Prizes of the International Festival for Pediatric Patients Paintings (with musical intermissions) 20:00 20:15 Closing Ceremony of USERN Festivals and UNESCO World Science Day Day 2: Sunday, November 11, 2018 Epidemiology and Manifestations of PIDs 9:00 9:10 Opening of the 4th PID Course - Giovanni Romeo (IT) and Nima Rezaei (IR) 9:10 9:30 Introduction to Calabria Grecanica and ESGM - Giovanni Romeo (IT) 9:30 10:15 The most recent discoveries in the Primary Immunodeficiency Diseases field - Nima Rezaei 10:15-11:00 An overview of PID pathogenic mechanisms in PID - Marco Gattorno (IT) 11:00-11:30 Coffee Break 11:30-12:15 EBV associated Immunodeficiencies - Kathleen Sullivan (USA) 12:15-13:00 Newborn screening for immunodeficiency - Lennart Hammarstrom (SE) 13:00 13:45 Keynote Speech The Genetics of Autism -Evan Eichler (USA) 13:45 14:15 Question and Answers for the Whole Session 14:15 15:30 Buffet Lunch 15:30 17:30 Round table discussion on PID comorbidities, genetic disorders and vaccines (with the participation of patients and families)
3 Day 3: Monday, November 12, 2018 Diagnostic and Therapeutic Approaches for PID 9:00-9:45 Trans-omics beyond the genetics of PID - Lennart Hammarström (SE) 9:45-10:30 New horizons in immunophenotyping for PID diagnosis - Mirjam van der Burg (NL) 10:30-11:15 Early onset IBD - Kathleen Sullivan (USA) 11:15-11:45 Coffee Break 11:45-12:30 Update on treatment of primary antibody deficiencies - Alessandro Plebani (IT) 12:30 13:15 Gene therapy for primary immunodeficiencies - Alessandro Aiuti (IT) 13:15 14:00 Immune reconstitution after HSCT - Eleonora Gambineri (IT) 14:00-15:00 Buffet Lunch 15:00 15:30 Question and Answers for the morning session 15:30-17:00 Posters Vision and PID Clinic 1 with patients from Calabria Grecanica Day 4: Tuesday, November 13, 2018 Translational Immunology and Immunogenetics 9:00-9:45 New Immune Dysregulation Defects - Kaan Boztug (A) 9:45-10:30 Immune Dysregulation: mechanisms, diagnostics, and therapeutics - Craig Platt (USA) 10:30-11:15 Autoimmune cytopenias as a new warning sign of PID - Eleonora Gambineri (IT) 11:15-11:45 Coffee Break 11:45 12:30 Update on autoinflammatory diseases with immunodeficiencies - Marco Gattorno (IT) 12:30 13:15 DNA repair failures in the immune system - Mirjam van der Burg (NL) 13:15 13:45 Question and Answers for the whole session 13:45-14:45 Buffet Lunch 14:45 17:00 USERN PID Workshop: NGS Data Analysis - Craig Platt (USA) Day 5: Wednesday, November 14, :00 9:30 Best Posters Presentations and Awards 9:30 11:00 PID Clinic 2 with patients from Calabria Grecanica 11:00 11:30 Coffee Break
4 11:30 12:00 Closing Ceremony Inauguration Day: Saturday, November 10, 2018 Some references to the Institutions and contents mentioned in this program Buildings of the Università Mediterranea of Reggio Calabria, where the USERN 2018 Congress and Prize Awarding Festival + Post PID Course will be hosted 10 November, UNESCO World Science Day for Peace and Development ( USERN The Universal Scientific Education and Research Network (USERN) was inaugurated in 2015 aiming at the diffusion of science without borders through peaceful and humanitarian universal initiatives in the fields of education and research. Its membership includes some of the top 1% scientists from 21 scientific fields as advisory board members who manage and supervise the educational and research programs. There are more than 6,500 additional members from 65 countries. More than 13 Nobel Laureates and 300 top scientists accepted to serve as advisory board members. The USERN prize is an international award, established by the USERN, which every year is bestowed upon junior researchers less than 40 years of age for any novel advancement or achievement in scientific education, research, or serving the humanity in five fields, including formal sciences, physical sciences, biological sciences, medical sciences, and social sciences. The International Festival for Awarding USERN prize is held every year on November 10 th in the World Science Day for Peace and Development. European School of Genetic Medicine: Since 1988 more than 7000 young geneticists, in particular physicians and biologists, have been trained by the European School of Genetic Medicine (ESGM). They come to Italy from everywhere in Europe, from the Southern rim of the Mediterranean sea, from the Middle East and from all over the world. ESGM is recognized and sponsored with scholarships by many Universities across Europe, by the European Society of Human Genetics
5 (ESHG) and by other scientific societies. ESGM is therefore having a tremendous impact on the practice and research in human/medical genetics far beyond Europe. Primary immunodeficiency diseases (PID) PID are a heterogeneous group of inherited disorders with defects in one or more components of the immune system. Some of these disorders have a frequency of 10-fold higher the Calabria Grecanica with respect to other parts of Italy. Monogenic PID may provide unique opportunities to uncover the genetic bases and mechanisms of complex autoimmune disorders (AID), the study of which has already helped to unravel the pathways that drive autoimmunity. The PID course organized in conjunction with the annual USERN meeting addresses the need to increase awareness of these conditions worldwide and also to define the resource requirements for diagnosis, genetic counseling and treatment in the Calabria Grecanica. Calabria Grecanica ISASI: CNR Institute for research on Autism Bronzi di Riace (Riace s Warriors) at the Museo Archeologico Nazionale di Reggio Calabria
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