Madan M. Rehani, Pedro Ortiz López International Atomic Energy Agency Vienna, Austria
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1 Keynote Lecture IRPA12, TS II.2.4 Protection of Patients in Medical Exposures Madan M. Rehani, Pedro Ortiz López International Atomic Energy Agency Vienna, Austria
2 Topics What is patient protection in medical exposure Magnitude of the problem How to achieve patient protection IAEA Resources
3 What is meant by Radiation Protection of Patients Diagnostic X ray & nuclear medicine examinations Interventional Procedures Purpose is not to give radiation exposure but to achieve diagnosis or specific clinical purpose- thus reduction of dose is the AIM, without compromising on quality Radiotherapy: Radiation is deliberately given to kill cells or achieve pain relief- So reduction of dose in NOT the aim But unnecessary dose reduction- Yes
4 What we want to achieve in Patient Protection Overall objective: Benefits outweighing the risks Specific objectives: 1. Radiation exposure should be no more than necessary for getting the desired clinical information or the outcome of the procedure; and 2. Deterministic injuries in interventional procedures and accidental exposures in radiotherapy should be avoided. 3. Communication with the patient and assurance to the patient that the patient is getting radiation exposure no more than necessary and that at this level of radiation exposure, the risks are much smaller than the benefits
5 Topics What is patient protection in medical exposure Magnitude of the problem How to achieve patient protection IAEA Resources
6 The size of the issue- Global (UNSCEAR)* Annually About 3.6 billion diagnostic X-ray examinations About 35 million nuclear medicine examinations About 5 million patients radiotherapy treatments * Report yet to be released
7 Then & Now Previously: I have to work whole life with radiation, whereas the patient may undergo procedure only few times Now 200 1
8 Then & Now Staff Patients
9 Long fluoroscopy times and/or thick body masses Coronary Angioplasty lbs; 63 min FT Radiofrequency Ablation 17 yo; ~ min FT TIPS placement lb Coronary angioplasty 350 lb; 50 min FT Courtesy L. Wagner Coronary angioplasty 75 yo woman; 42 min FT Uterine Embolization 270 lb, 5 2 ; ~34 cm thick
10 A patient may get more radiation exposure in 5 CT scans than a staff working in X ray department for full working life with adequate protection
11 Cataract in the eye of interventional radiologist s Staff protection in some situations is still important
12 TOTAL ~ msv Nuclear power < msv Occupational Chernobyl Atmospheric testing Medical 0.61 msv > 99.97% Global annual per caput dose from man-made sources ( ) UNSCEAR 2008 Unpublished
13 A word of history Before the 70 s patient protection, not an issue, excluded from safety standards 1973 First national survey in the USA ( NEXT programme) Early 80 s surveys in UK, 1984 EC- Medical Directive 1991 first Agency s CRP on dose reduction 1996 BSS includes patient protection 2001 First International Conference, Unit on the Radiological Protection of Patients established 2002, Approval of International Action Plan (IAEA)
14 Topics What is patient protection in medical exposure Magnitude of the problem How to achieve patient protection IAEA Resources
15 Diagnostic Radiology Patient Protection in
16 Specific situations: Radiography TWO MAIN things that have helped immensely in patient protection: 1.Introduction of better intensifying screens (rare earth) resulting in halving of radiation dose to patient 2.Diagnostic Reference Levels (DRL)
17 Trends in average effective doses for medical examinations (UNSCEAR 2008) Average effective dose per examination (msv) Examination Health care level I Chest radiography Abdomen X-ray Mammography
18 Are there further challenges in Radiography? Some developing countries are where developed countries were 30 years ago (e.g.next, NRPB ) There are number of countries that are still using calcium tungstate screens and manual film processing They need to go through the exercise Going through the PROCESS is: Educative Build capability in dose assessment and dose management
19 Are there further challenges in Radiography? Many countries have shifted or are shifting to digital radiography Easy to delete images and not know what happened Use of improper field size- common Diagnostic image can be obtained at 50% of dose but generally doses have increased by 2 times Unclear where problems really is in the data stream Popularity and ease is making for increased frequency Result: Patients getting MORE DOSE than necessary
20 Are there further challenges in Radiography? How often have studies shown patient doses higher than DRL, including in developing countries?
21 AJR June 2008
22 Are there further challenges in Radiography? DRLs need to be reduced Most people do not take into account higher screen speed Advice: Look for bigger fish
23
24 Trends in average effective doses for medical examinations (UNSCEAR 2008) Average effective dose per examination (msv) Examination Health care level I Chest radiography Abdomen X-ray Mammography CT scan * *Type of equipment varied from single to multi slice
25 Global CT data ( ) Wide variation in equipment among well developed countries (~ 10 fold): 93 scanners per million population in Japan 32 in the US 14 in Germany, Finland and Spain and 7-8 in U.K and France ~40,000 CT scanners worldwide ~ million CT scans done annually Globally CT scans are about 5% of x-ray procedures and account for 35-40% of collective effective dose (~0.8 of 2.3 million person-sv)
26 Collective effective population doses: Comparison ~ 2,000 person-sv annually from occupational exposure ~2,300,000 person-sv annually from radiology. ~800,000 person-sv annually from CT ~400,000 person-sv worldwide over all time from entire Chernobyl release* * UNSCEAR 2007
27 Patient dose management in CT Reference dose quantities have been agreed upon (CTDI, DLP) There are people who argue death of CTDI Most modern machines now provide dose value (CTDIv, DLP) DRLs for adult are well established Dose/exam can be but in actual practice Collective dose by few 100% (600%)
28 Is there a cancer risk from CT? 1.4 Relative risk CT scan sequence 3-phase CT liver scan % of CT scan patients A-bomb data show 50 a statistically significant increase at > 50 msv Organ dose (msv)
29 Pediatric CT DRL for children not yet widely agreed upon, but UK & some other countries values available for different age groups Issue of pediatric phantom
30 Arch & Frush. Pediatric body MDCT: A 5-year follow-up survey AJR August 2008 Web-based survey, comparing data w.r.t to pediatric radiologists in 61 responses Significant reduction in kvp, mas 98% use weight-based adjustment in tube current Awareness main factor
31 Wallace et al. IRPA12, pediatric hospitals in Australia Dose reduction through MDCT optimization seminar DLP & Effective dose >50% reduction Role of training
32 DLP for chest CT > DRL Estonia Czech Republic Bosnia & HerzegovinaBulgaria (Republic of Srpska) Serbia Morocco MaltaMacedonia Tunisia Syria Kuwait Algeria Japan Ghana Sudan Kenya Tanzania Thailand
33 Computed Tomography In a number of countries adult exposure factors are being used for CT examinations of Children
34
35 Automatic Exposure Control Quite a large number of reports documenting benefits Personal interactions- many places find it impracticable- reason: image quality Academic centres with expertise in use of AEC find that claims as in research papers are valid
36 Automatic Exposure Control Dose increases if one does not select factors properly e.g. Noise index or image quality parameter If one selects High noise index- poor image quality, low dose Low noise index- good quality, high dose Example: Kidney for stones: unlikely to be missed even in low dose scan, but for appendicitis- higher dose scan is needed Heavy patient- upper value may reach
37 Patient Doses in CT- Future aspects Are there reports of patient dose changes in any department with time? Practically No Are there reports of holistic look? e.g. reduction by AEC ) say 30%, shielding (say 30%), centring of patient properly (say X%). No Total dose reduction?--no
38 Learning from Success Stories Occupational radiation protection Dose limits have been continuously brought down (1930 s- 500 msv to 20 msv/year now, Actual doses are 1 msv/yr for 95% of staff
39 Patient dose management in CT What is the single most important carry home point? Appeal to our distinguished colleagues sitting here to develop mechanism to be able to say that my patient was getting..x.. dose in (say) 2002 and gets..y.. dose now?
40 Use of DRLs We can ALL tell that the Car was costing X.. in (say) 2002, now it costs Y, Same about the salary.the house rent etc. Keep a regular record of patient dose for individual study (say abdomen, CTA ) in DRL quantities and show how it has changed with time.
41 Patient Protection in interventional procedures using X rays
42 Interventional Procedures The focus shifts from stochastic risk to deterministic injuries Earlier lack of awareness Equipment were not geared to measure dose Now KAP meters (stochastic risk) and new equipment with cumulative air kerma (for deterministic risk) Gaf chromic dosimtery films
43 Patient protection in Interventional Procedures DRLs for some procedures e.g. PTCA Initial reaction to DRL- not positive Complexity index
44 Udine- Cardiac Interventions Number of procedures per patient >7 Number of patients Number of Patients Mean DAP Number of patients with DAP>300Gycm Gycm % Nearly 6% of patients had 3 or more interventions
45 PTCA values exceeding Reference levels (KAP) Out of 20 countries for which data is available, 11 >Ref levels Slovenia Croatia Bulgaria Tunisia Algeria Lebanon Syria UAE Pakistan Thailand Kenya
46 Patients PSD >2 Gy. Lithuania Slovenia Croatia Bosnia & Herz. Armenia Tunisia Algeria Lebanon Syria Pakistan Thailand
47 Patient Protection Results from IAEA project in Latin American Countries (RLA9057): Please see the IRPA12 Abstract Book for papers in Interventional CT Mammography Radiography
48 Topics What is patient protection in medical exposure Magnitude of the problem How to achieve patient protection IAEA Resources
49
50 Approved Training Package IAEA Training Material on Radiation Protection in Diagnostic and Interventional Radiology Dose Area Product (DAP) Transm ission ionization cham ber in collaboration with Version: January 2005
51 Approved Training Package IAEA Training Material on Radiation Protection in Radiotherapy Accidental exposure Transport Use a m obile safe this can double up as em ergency container Treating 4 blocks as one Computer calculates correct treatment tim e Catheters indexed to avoid mixing up Lessons learned from accidental exposures in radiotherapy Inappropriate use of treatm ent planning C onsequences of accidents in collaboration with Version: January 2005
52 Approved Training Package IAEA Training Material on Radiation Protection in Nuclear Medicine READY FOR A NEW PATIENT A Radiation Safe sign is posted at the door after decontamination and clearing of room King Faisal Specialist Hospital and Research Center, Riyadh Shall the patient be hospitalized? Can the patient leave? Any restrictions? PREGNANCY AFTER THERAPY Radiopharmaceutical All activities Avoid pregnancy up to (MBq) (months) Au-198 colloid I-131 iodide (thyroid ca) I-131 iodide (thyrotoxicosis) I-131 MIBG P-32 phosphate Sr-89 chloride Y-90 colloid (arthritic joints) Y-90 colloid (malignancy) BREASTFEEDING SAFE ADMINISTRATION PATIENT SURVEY Typical Graph of the Exposure Rate at 1 m from the Patient Administered with of 5.5 GBq I Exposure Rate (mr/hr) Avoid mis-administration Days of Isolation Abdalla Al-Haj in collaboration with Version: January 2005
53 Draft Training Package IAEA Training Material on Radiation Protection in PET/CT in collaboration with Version: September 2008
54
55 Dissemination CD is sent to anyone who requests to or to anyone in the Unit Professional societies are given permission to make copies of CDs and distribute to members Conference organizers also given permission
56 Training courses- Medical Since regional training courses have been organized and 35 national training courses have been supported
57
58 IAEA Regional Projects Projects on patient dose management in radiography, interventional procedures, mammography and CT Latin America: RLA 9057 Europe: RER 9093 Asia: RAS 9047 Africa: RAF
59 Patient Protection in Radiotherapy
60
61
62
63 Summary There is definite progress in radiological protection of patient Doses in radiography have reduced Patient doses in CT have increased Interventional procedures require attention Multiple procedures on same patient is becoming a BIG issue
64 Working towards making medical exposure a Safer practice
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