Probabilistic Risk-Cost-Benefit Analysis of Additional Benzene Emissions Controls

Size: px
Start display at page:

Download "Probabilistic Risk-Cost-Benefit Analysis of Additional Benzene Emissions Controls"

Transcription

1 Probabilistic Risk-Cost-Benefit Analysis of Additional Benzene Emissions Controls Arthur F. Eidson, Ph.D. Senior Risk Assessor The Shaw Group 1401 Enclave Parkway, Suite 250 Houston, Texas June 16, 2010

2 Overview Problem and Objective Emission controls upgrade plant expansion Estimate cost of derived health risk benefit Analytical Methods Analysis of risk, benefit, and cost Uncertainties Probabilistic analysis Conclusions

3 Problem and Objective Petrochemical Plant Expansion Additional equipment required to meet MACT standard for benzene Cost and Benefit Costs being developed by Plant Benefits Continued favorable regulatory compliance Continued good standing with local public groups Increased production throughput What is the cost of the human health risk benefit for benzene vapor controls?

4 Vapor Dispersion Modeling Benzene vapor emission rate estimates Current and proposed control equipment Local meteorological data Dispersion modeling (AERMOD; EPA, 2003) Not strongly sensitive to terrain Predicted/Observed concentrations - City locations Average: 0.70 Range: 0.83 x Average to 1.40 x Average 10th and 90th percentiles of lognormal distribution assumed

5 Receptor Locations

6 Modeled Air Concentrations at City Receptor Locations

7 Inhalation Pathway Exposure C i FLoc i EF i ED i E R = i AT E R = benzene exposure of population R (µg/m 3 ) C i = benzene concentration at location i (µg/m 3 ) FLoc i, EF i (days/year), ED i (years) AT = averaging time (70 years = 25,550 days)

8 Exposure Parameters Receptors Students Hospital Lifetime Residents Workers a Elementary High School College Patient Resident b General Exposure Factors Exposure Frequency, EF (days/year) Exposure Duration, ED (year) - Child c 7 7 Exposure Duration, ED (year) - Adult d Averaging Time-carcinogens, ATc (days) 25,550 Fraction of Time at Location (FLoc) Residence (FRes) 1.00 (1-FW) (1-FEs) (1-FHs) None (1-FH) b Workplace (FW) (8 hr/day) 0.33 FW Elementary School (FEs) (6.5 hr/day) 0.27 FEs High School (FHs) (6.5 hr/day) 0.27 FHs College (FC) (campus resident) 1.00 FC Hospital Patient (FH) (one year) 1.00 FHs a Workers at Schools, College, Hospital b Lifetime resident attending elementary school, high school, college, working at elementary school (highest special location benzene concentration). FRes = (FW+FEs+FHs+FC+FH). c Resident from childhood (age 1 through 7) to adulthood (age 7 through 31). d Resident as adult for entire exposure duration.

9 Risk Characterization General Risk Equation ELCR R E R URF ELCR R = Excess Lifetime Cancer Risk Probability of cancer occurrence from benzene in population R above unexposed population with same characteristics

10 Benzene Toxicity Benzene is a carcinogen URF range (EPA IRIS, 2006) 2.2E-6 (µg/m 3 ) -1 to 7.8E-6 (µg/m 3 ) -1 Age Dependent Adjustment Factor (ADAF) Applies to carcinogens with mutagenic mechanism Benzene action unclear (EPA, 2005), ADAF = 1 here URF assumptions Uniform distribution over URF range

11 Cost Analysis Net Present Value of Proposed Controls Capital Cost of Equipment - $51.7M Assumption: normal distribution ± $100K Operation and Maintenance (O&M) - $100K/yr Assumption: normal distribution ± $10K std dev Depreciation 30 yr Discount Rate 10% (EPA, 1983; OMB, 1996) Assumption: normal distribution ± 1% std dev

12 Health Risk Benefit Analysis Health Benefit Reduced cancer risk achieved by new controls Monetizing benefit is subjective to many risk assessors Economists address willingness to pay (WTP) Such data not available at this time Avoided cancer cases from benzene inhalation discussed here

13 Cost Cost Benefit Ratio Net Present Value of proposed controls ($NPV) Benefit Expected benzene cancer cases = ELCR x City population of 112,000 Avoided cases = Baseline cases Controlled cases Cost/Benefit Ratio Cost/Benefit = $NPV per Benzene Cancer Cases Avoided

14 Probabilistic Analysis Effect of Uncertainty Assumptions on: Risk Estimates (Cancer Cases Avoided) Benzene concentrations, occupancy factors, toxicity factors Cost Estimates ($NPV) Capital, O&M, depreciation, discount rate Cost/Benefit Ratio $NPV / Benzene Cancer Case Avoided

15 Modeled Baseline Concentrations

16 Modeled Controlled Concentrations

17 Maximum Reduction in Risk

18 Risk Benefit

19 Cost Estimate

20 Cost per Cancer Case Avoided

21 Cost per Cancer Case Avoided

22 Cost / Benefit Ratio Mean Value Estimate Average = $72.4M per case Most likely = ~$67M per case 95% probability $43M to $117M per case

23 Conclusions Most likely cost per benzene cancer case avoided somewhat similar to capital cost (~$52M) Other benefits not considered here Cancer reduction from carcinogens other than benzene Regulatory compliance (penalties avoided) Continued good public standing Increased production from upgraded plant

24 References U.S. Environmental Protection Agency (USEPA), 2003, AERMOD: Latest Features and Evaluation Results, EPA-454/R , June. U.S. Environmental Protection Agency (USEPA), 2008, Integrated Risk Information System (IRIS), accessed at U.S. Environmental Protection Agency (USEPA), 2005, Guidelines for Carcinogen Risk Assessment, EPA/630/P-03/001B, Risk Assessment Forum, Washington, D. C. March 25. U.S. Environmental Protection Agency (USEPA), 1983, Guidelines for Performing Regulatory Impact Analysis, as updated through 1991, Office of Policy, Planning, and Evaluation, Washington, D. C. Office of Management and Budget (OMB), 1996, Economic Analysis of Federal Regulations Under Executive Order 12866, January 11.

25 Disclaimer To the extent permissible by law, The Shaw Group assumes no responsibility for information presented herein and disclaims all liability in respect of such information. Shaw is not liable for any injury and/or damage to persons or property as a result of any actual or alleged infringements of intellectual property or privacy rights, professional or product liability, whether resulting from negligence or otherwise, including without limitation, from any use or operation of any ideas, instructions, procedures, products or methods contained in the material presented herein. Shaw does not warrant that the information provided is accurate or free from error. Information provided is intended solely for the purpose of providing general information.

1, 2, 3-Trichloropropane (TCP): Assessment of Risks from Drinking Water

1, 2, 3-Trichloropropane (TCP): Assessment of Risks from Drinking Water 1, 2, 3-Trichloropropane (TCP): Assessment of Risks from Drinking Water 1, 2, 3-Trichloropropane (TCP): Assessment of Risks from Drinking Water Prepared for Alaimo Group (Engineers and Architects) 200

More information

Risk Characterization

Risk Characterization Risk Characterization 1 Learning Objectives By the end of this module, participants should have an understanding of: The purpose of risk characterization Integrating the results of hazard identification,

More information

ETHYLENE OXIDE: AN UPDATE

ETHYLENE OXIDE: AN UPDATE May 23, 2012 ETHYLENE OXIDE: AN UPDATE BILL GULLEDGE ACC s Ethylene Oxide Panel EO Panel Overview ACGIH TLV Review of EO EPA Development of EO IRIS Assessment Other Activities- EO Mode of Action Ethylene

More information

Ethylene Oxide

Ethylene Oxide Ethylene Oxide 75-21-8 Hazard Summary The major use of ethylene oxide is as a chemical intermediate in the manufacture of ethylene glycol. Ethylene oxide is also used as a sterilizing agent for medical

More information

APPENDIX IV.I.1. Delivery Truck HRA

APPENDIX IV.I.1. Delivery Truck HRA APPENDIX IV.I.1 Delivery Truck HRA Diesel Particulate Matter (DPM) Health Risk Assessment (HRA) of Delivery Trucks from the Project at Pico and Sepulveda, Los Angeles, California Introduction This health

More information

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY REGION IX 75 Hawthorne Street San Francisco, CA 94105

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY REGION IX 75 Hawthorne Street San Francisco, CA 94105 UNITED STATES ENVIRONMENTAL PROTECTION AGENCY REGION IX 75 Hawthorne Street San Francisco, CA 94105 To: From: Interested Parties ;;f\i Lynn Suer, Ph.D.1:t::J Remedial Project Manager Superfund Division

More information

Updates to HSRA Risk Reduction Standards

Updates to HSRA Risk Reduction Standards Updates to HSRA Risk Reduction Standards Georgia AWMA Regulatory Update Conference May 11, 2017 Chris Saranko, Ph.D, DABT Atlanta, GA Presentation Outline 2017 Hazardous Site Response Rulemaking Phased

More information

Appendix C Risk Calculations Western Margin of Northern Plumes

Appendix C Risk Calculations Western Margin of Northern Plumes Appendix C Calculations Western Margin of Northern Plumes Consolidated Human Health Assessment - 2010 General Parameters Air s During Irrigation (Reference: Guidelines for the Assessment and Management

More information

RISK ASSESSMENT OF EXPOSURE TO BENZENE, TOLUENE AND FORMALDEHYDE IN RESIDENTIAL ENVIRONMENT IN CHINA

RISK ASSESSMENT OF EXPOSURE TO BENZENE, TOLUENE AND FORMALDEHYDE IN RESIDENTIAL ENVIRONMENT IN CHINA RISK ASSESSMENT OF EXPOSURE TO BENZENE, TOLUENE AND FORMALDEHYDE IN RESIDENTIAL ENVIRONMENT IN CHINA C Zheng 1, GQ Zhang 1,*, J.H Hao 2, J.P Lin 2, YH Liu 2 1 College of Civil Engineering, Hunan University,

More information

Development of NJ Human Health-based Criteria and Standards

Development of NJ Human Health-based Criteria and Standards Development of NJ Human Health-based Criteria and Standards Gloria Post NJDEP Office of Science Presented to: Public Health Standing Committee October 18, 2010 Human Health-based Criteria and Standards

More information

APPENDIX I. Soil Risk Calculation Supporting Details. Revised EE/CA. Lower Duwamish Waterway Superfund Site: T-117 Early Action Area

APPENDIX I. Soil Risk Calculation Supporting Details. Revised EE/CA. Lower Duwamish Waterway Superfund Site: T-117 Early Action Area APPENDIX I Soil Risk Calculation Supporting Details Lower Duwamish Waterway Superfund Site: T-117 Early Action Area Revised EE/CA Appendix I. Soil Risk Calculation Supporting Details This appendix provides

More information

Sacramento Rendering Company Health Risk Assessment

Sacramento Rendering Company Health Risk Assessment Sacramento Rendering Company Health Risk Assessment The SMAQMD regulates emissions of toxic substances under Rule 402 and SMAQMD s guidance document, Health Risk Management Programs for Existing, Modified

More information

Chapter 6 Quantifying Exposure

Chapter 6 Quantifying Exposure What s Covered in Chapter 6: Chapter 6 Quantifying Exposure 6.1 Inhalation Exposure Pathways 6.2 Ingestion Exposure Pathways 6.3 Dermal Exposure Pathways 6.4 Exposure Frequency 6.5 Exposure Duration 6.6

More information

Updated Health Risk Assessment Guidelines

Updated Health Risk Assessment Guidelines Updated Health Risk Assessment Guidelines California OEHHA s Air Toxics Hot Spots Program March 31 st, 2015 Insert then choose Picture select your picture. Right click your picture and Send to back. Copyright

More information

UNIVERSAL C/P BRONZE Version 1.1 Print Date 07/03/2009 REVISION DATE: 09/01/2006

UNIVERSAL C/P BRONZE Version 1.1 Print Date 07/03/2009 REVISION DATE: 09/01/2006 SECTION 1 - PRODUCT IDENTIFICATION Trade name : Product code : 015101 529 COMPANY : Tremco Incorporated 3735 Green Road Cleveland, OH 44122 Telephone : (216) 292-5000 8:30-5:00 EST Emergency Phone: : (216)

More information

and Benchmark Toxicology Services HEALTH RISK ASSESSMENT OF ATMOSPHERIC EMISSIONS EXPANSION OF WAGERUP REFINERY TO 4.7 MTPA

and Benchmark Toxicology Services HEALTH RISK ASSESSMENT OF ATMOSPHERIC EMISSIONS EXPANSION OF WAGERUP REFINERY TO 4.7 MTPA and Benchmark Toxicology Services HEALTH RISK ASSESSMENT OF ATMOSPHERIC EMISSIONS EXPANSION OF WAGERUP REFINERY TO 4.7 MTPA for Alcoa World Alumina Australia ENVIRON Australia Pty Ltd Level 2, Adelaide

More information

GPS Safety Summary Diethylene glycol methyl ether

GPS Safety Summary Diethylene glycol methyl ether GPS Safety Summary Diethylene glycol methyl ether This Product Safety Summary is intended to provide a general overview of the chemical substance. It contains basic information and is not intended to provide

More information

Risk Assessment Report for AGSS-ICS

Risk Assessment Report for AGSS-ICS 1. INTRODUCTION This Risk Assessment evaluated the human health risks from exposure during and after application of AGSS-ICS. This information will determine whether AGSS-ICS used to treat soil will present

More information

HEALTH CONSULTATION. Tom Lea Park EL PASO COUNTY METAL SURVEY EL PASO, EL PASO COUNTY, TEXAS EPA FACILITY ID: TX

HEALTH CONSULTATION. Tom Lea Park EL PASO COUNTY METAL SURVEY EL PASO, EL PASO COUNTY, TEXAS EPA FACILITY ID: TX HEALTH CONSULTATION Tom Lea Park EL PASO COUNTY METAL SURVEY EL PASO, EL PASO COUNTY, TEXAS EPA FACILITY ID: TX0000605388 September 6, 2002 Prepared by: The Texas Department of Health Under a Cooperative

More information

TRICHLOROETHYLENE: ASSESSING & MANAGING VAPOR INTRUSION RISKS. Kelly Schumacher EPA Region 7

TRICHLOROETHYLENE: ASSESSING & MANAGING VAPOR INTRUSION RISKS. Kelly Schumacher EPA Region 7 TRICHLOROETHYLENE: ASSESSING & MANAGING VAPOR INTRUSION RISKS Kelly Schumacher EPA Region 7 TCE CHRONIC RFC = 2 MCG/ M 3 Two co-critical endpoints (each can support RfC independently) Autoimmune disease

More information

Human Health Risk Assessment. Marian Olsen U.S. EPA ERRD October 13, 2011

Human Health Risk Assessment. Marian Olsen U.S. EPA ERRD October 13, 2011 Human Health Risk Assessment Marian Olsen U.S. EPA ERRD October 13, 2011 Presentation Overview Conceptual Site Model Defining Risk Assessment Conceptual Site Model Superfund Risk Assessment Process Data

More information

: EPDM REPAIR TAPE - 6" CURED

: EPDM REPAIR TAPE - 6 CURED SECTION 1 - PRODUCT IDENTIFICATION Trade name Product code COMPANY Telephone Emergency Phone: Product use : : 68106B503 : Tremco Incorporated 3735 Green Road Cleveland, OH 44122 : (216) 292-5000 8:30-5:00

More information

Company overview. Highlights for the 1 st quarter 2018 (January-March)

Company overview. Highlights for the 1 st quarter 2018 (January-March) Company overview Vaccibody is a clinical-stage biopharmaceutical company dedicated to the discovery and development of novel immunotherapies. The company is a leader in the rapidly developing field of

More information

Substance Evaluation Conclusion document EC No SUBSTANCE EVALUATION CONCLUSION DOCUMENT. as required by REACH Article 48.

Substance Evaluation Conclusion document EC No SUBSTANCE EVALUATION CONCLUSION DOCUMENT. as required by REACH Article 48. SUBSTANCE EVALUATION CONCLUSION DOCUMENT as required by REACH Article 48 for Buta-1,3-diene EC No 203-450-8 CAS No 106-99-0 Evaluating Member State(s): Germany 22 October 2015 Evaluating Member State Competent

More information

Applications of Genomics to Toxic Torts

Applications of Genomics to Toxic Torts Applications of Genomics to Toxic Torts Gary Marchant & Andrew Askland Arizona State University College of Law Center for the Study of Law, Science, & Technology Potential Uses of Toxicogenomics Medical

More information

POWERPLY 300 FR - WHITE GRANULE Version 1.0 Print Date 04/15/2013 REVISION DATE: 04/12/2013

POWERPLY 300 FR - WHITE GRANULE Version 1.0 Print Date 04/15/2013 REVISION DATE: 04/12/2013 SECTION 1 - PRODUCT IDENTIFICATION Trade name : Product code : 36300FR601 COMPANY : Tremco Incorporated 3735 Green Road Cleveland, OH 44122 Telephone : (216) 292-5000 8:30-5:00 EST Emergency Phone: : (216)

More information

Pesticide Product Labels What the label says.and Why. Dr. Jeff Birk BASF Corporation Regulatory Manager

Pesticide Product Labels What the label says.and Why. Dr. Jeff Birk BASF Corporation Regulatory Manager Pesticide Product Labels What the label says.and Why Dr. Jeff Birk BASF Corporation Regulatory Manager Regulation of Pesticides The pesticide industry is regulated by the USEPA. The pesticide industry

More information

Risk Assessment Approaches for Nanomaterials

Risk Assessment Approaches for Nanomaterials Risk Assessment Approaches for Nanomaterials Eileen D. Kuempel, PhD Nanotechnology Research Center Education and Information Division National Institute for Occupational Safety and Health The findings

More information

CHARACTERIZING THE IMPACTS OF UNCERTAINTY AND SCIENTIFIC JUDGMENT IN EXPOSURE LIMIT DEVELOPMENT

CHARACTERIZING THE IMPACTS OF UNCERTAINTY AND SCIENTIFIC JUDGMENT IN EXPOSURE LIMIT DEVELOPMENT CHARACTERIZING THE IMPACTS OF UNCERTAINTY AND SCIENTIFIC JUDGMENT IN EXPOSURE LIMIT DEVELOPMENT Andrew Maier, Ph.D., CIH, DABT TERA Robert Sussman, Ph.D., DABT SafeBridge Consultants, Inc. Bruce Naumann,

More information

of HAWAI'I UNIVERSITY MEMORANDUM NUMBER TO: M.R.C. Greenwood President University of Hawaii VIA:

of HAWAI'I UNIVERSITY MEMORANDUM NUMBER TO: M.R.C. Greenwood President University of Hawaii VIA: UNIVERSITY of HAWAI'I SYSTEM MEMORANDUM NUMBER 12.07 Dl'i:.~ ~~446 Offtce of Capital knprowmentl April 12, 2012 TO: VIA: M.R.C. Greenwood President University of Hawaii Howard Todo A.-J ~ Vice President

More information

MATERIAL SAFETY DATA SHEET Consumer Product

MATERIAL SAFETY DATA SHEET Consumer Product Page 1 of 6 1. PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: GENERAL USE: Nail Care PRODUCT DESCRIPTION: PRODUCT FORMULATION NAME: CHEMICAL FAMILY: Nail Care GENERIC NAME: Green Pigment MANUFACTURER

More information

DEVELOPMENT OF THE CHROMIUM PUBLIC HEALTH GOAL

DEVELOPMENT OF THE CHROMIUM PUBLIC HEALTH GOAL DEVELOPMENT OF THE CHROMIUM PUBLIC HEALTH GOAL Robert A. Howd, Ph.D. Chief, Water Toxicology Unit Office of Environmental Health Hazard Assessment, California Environmental Protection Agency Oakland and

More information

Occupational exposure limits

Occupational exposure limits Occupational exposure limits Cancer is one of the most frequent causes of deaths due to occupational illness. There are industrial workplaces where it is impossible to prevent exposure to carcinogenic

More information

MAJOR ACCOMPLISHMENTS

MAJOR ACCOMPLISHMENTS Exposure Assessment Applications, LLC Mark R. Stenzel, President 6045 N. 27 th Street Arlington, VA 22207 703.532.2755 (phone) Mark_Stenzel@EAApps.com 703.532.2772 (fax) http://www.eaapps.com MAJOR ACCOMPLISHMENTS

More information

1Q 2014 Earnings Release

1Q 2014 Earnings Release 1Q 2014 Earnings Release April 2014 DISCLAIMER Financial results for 1Q 2014 are provisional and accordingly subject to change according to the outside independent auditors review. This presentation contains

More information

Max Chou Toxicologist and Certified Marine Chemist Trainee

Max Chou Toxicologist and Certified Marine Chemist Trainee Max Chou Toxicologist and Certified Marine Chemist Trainee Three Objectives: 1) Regulations regarding local toxic substances 2) Origin of regulations and extrapolation to maritime industry 3) The difference

More information

MATERIAL SAFETY DATA SHEET

MATERIAL SAFETY DATA SHEET MATERIAL SAFETY DATA SHEET 1. CHEMICAL PRODUCT AND COMPANY INFORMATION Manufacturer Name And Address Emergency Telephone Hospira, Inc. Product Names Synonyms Hospira, Inc. 275 North Field Drive Lake Forest,

More information

Table H3-1 Values Used for Daily Intake/Absorbed Dose Inhalation of Particulates

Table H3-1 Values Used for Daily Intake/Absorbed Dose Inhalation of Particulates Table H3-1 Values Used for Daily Intake/Absorbed Dose of Particulates Exposure Point Receptor Age: Particulates See Below Adult Exposure Parameter Parameter Definition Units RME RME Equation/ Route Code

More information

UNIVERSITY OF CALIFORNIA, BERKELEY 2020 LRDP FINAL EIR 11.2B REGIONAL & LOCAL AGENCY COMMENTS 11.2B.6 RESPONSE TO COMMENT LETTER B6 RESPONSE TO COMMENTS B6-1 THRU B6-3 See Thematic Response 8 for a comprehensive

More information

Outline: risk assessment. What kind of environmental risks do we commonly consider? 11/19/2013. Why do we need chemical risk assessment?

Outline: risk assessment. What kind of environmental risks do we commonly consider? 11/19/2013. Why do we need chemical risk assessment? Outline: Human health h and ecological l risk assessment Purpose of risk assessment Methodology for quantifying risk Case study: Children s exposure to As from CCA wood staircases Issues practical and

More information

Material Safety Data Sheet

Material Safety Data Sheet * * * Section 1 - Chemical Product and Company Identification * * * Chemical Name: Calcium Carbonate Product Use: Mineral Additive Synonyms: RiverCal 8102 GCC, RiverCal 8102 (C) GCC, RiverCal 8103 GCC,

More information

Development of safe levels of elemental impurities

Development of safe levels of elemental impurities Development of safe levels of elemental impurities ICH Q3D MASSET Dominique Head of Pharmaceutical Quality Non Clinical and Viral Safety Department Evaluation division 5 april 2016 EMA London Safe Levels

More information

Texas Private School Equitable Services Monitoring System

Texas Private School Equitable Services Monitoring System Texas Private School Equitable Services National Elementary and Secondary Education Act (ESEA) Conference Kansas City, Missouri LaNetra Guess Director and Texas Ombudsman Texas Education Agency Federal

More information

PAH - Sources and Measurement Mike Woodfield - AEAT

PAH - Sources and Measurement Mike Woodfield - AEAT PAH - Sources and Measurement Mike Woodfield - AEAT The Background (1) PAH in Ambient include substances known to produce cancer; World Health Organisation considers the risk to human health from ambient

More information

IHS CHEMICAL Upgradation of Pygas C 5 Cut to Produce Isoprene and Other Products

IHS CHEMICAL Upgradation of Pygas C 5 Cut to Produce Isoprene and Other Products ` IHS CHEMICAL Upgradation of Pygas C 5 Cut to Produce Isoprene and Other Products April 2016 ihs.com Upgradation of Pygas C 5 Cut to Produce Isoprene and Other Products Rajesh Kumar Verma Principal Analyst

More information

Exposure to Diesel Particulate Matter (DPM) During Construction

Exposure to Diesel Particulate Matter (DPM) During Construction Health Risk Assessment - Construction Exposure to Diesel Particulate Matter (DPM) During Construction Phase 1 Construction Receptors that would be exposed to DPM during construction of Phase 1 would include

More information

Benzene is potentially toxic, flammable, and unstable. It is a carcinogen, which means it can cause cancer. PPT-SM-B

Benzene is potentially toxic, flammable, and unstable. It is a carcinogen, which means it can cause cancer. PPT-SM-B Benzene Benzene is a clear, colorless liquid with a sweet odor. It is a natural component of crude oil and refined petroleum, volcanic emissions, and cigarette smoke. PPT-SM-B 2017 2 Benzene is potentially

More information

CHAPTER 8 RISK CHARACTERIZATION

CHAPTER 8 RISK CHARACTERIZATION CHAPTER 8 RISK CHARACTERIZATION This chapter describes the final step of the baseline health risk assessment process, risk characterization. In this step, the toxicity and exposure assessments are summarized

More information

MATERIAL SAFETY DATA SHEET THYROSYN (levothyroxine sodium) Tablets

MATERIAL SAFETY DATA SHEET THYROSYN (levothyroxine sodium) Tablets MATERIAL SAFETY DATA SHEET 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATIONS AND OF THE COMPANY UNDERTAKING Product Name Product Description Manufacturer/Supplier Address Thyroid replacement for dogs VEDCO,

More information

Sudbury Human Health Risk Assessment Briefing

Sudbury Human Health Risk Assessment Briefing Sudbury Human Health Risk Assessment Briefing September 22, 2008 Prepared by Environmental Defence September 22, 2008 The following report was commissioned by Mine-Mill Local 598CAW and Local 6500 Steelworkers

More information

Complete Policy Title: Tobacco & Smoke Free Campus Policy Approved by: Board of Governors (anticipated) Policy Number (if applicable):

Complete Policy Title: Tobacco & Smoke Free Campus Policy Approved by: Board of Governors (anticipated) Policy Number (if applicable): Page 1 Complete Policy Title: Tobacco & Smoke Free Campus Policy Approved by: Board of Governors (anticipated) Date of Original Approval(s): Policy Number (if applicable): Date of Most Recent

More information

MATERIAL SAFETY DATA SHEET

MATERIAL SAFETY DATA SHEET MATERIAL SAFETY DATA SHEET 1. PRODUCT AND COMPANY IDENTIFICATION Product Chemical characterization Supplier Enzyme Mix Buffered Enzyme Mix Solution Edge BioSystems 201 Perry Parkway, Suite 5 Gaithersburg,

More information

GPS Safety Summary White mineral oil (petroleum)

GPS Safety Summary White mineral oil (petroleum) GPS Safety Summary White mineral oil (petroleum) Chemical Identity Name: White mineral oil (petroleum) CAS number: 8042 47 5 IUPAC name: White mineral oil (petroleum) Molecular formula: UVCB substance

More information

Screening Level Health Risk Assessment of PCCD/PCDF Contamination Da Nang Airbase Case Study

Screening Level Health Risk Assessment of PCCD/PCDF Contamination Da Nang Airbase Case Study Regional Capacity Building Program for Health Risk Management of Persistent Organic Pollutants (POPs) in South East Asia Program 7/15/2009 SLIDE 1 Screening Level Health Risk Assessment of PCCD/PCDF Contamination

More information

MATERIAL SAFETY DATA SHEET RILEXINE (cephalexin monohydrate) Chewable Tablets

MATERIAL SAFETY DATA SHEET RILEXINE (cephalexin monohydrate) Chewable Tablets MATERIAL SAFETY DATA SHEET 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATIONS AND OF THE COMPANY UNDERTAKING Product Name Product Description Chewable antibiotic tablets for dogs Manufacturer/Supplier Virbac

More information

Approaches to Integrating Evidence From Animal and Human Studies in Chemical Assessments

Approaches to Integrating Evidence From Animal and Human Studies in Chemical Assessments Approaches to Integrating Evidence From Animal and Human Studies in Chemical Assessments Kris Thayer, National Center for Environmental Assessment (NCEA) Integrated Risk Information System (IRIS) Division

More information

MATERIAL SAFETY DATA SHEET NAME OF PRODUCT: Protect 2000/2100 Part B MSDS DATE: 2/18/13

MATERIAL SAFETY DATA SHEET NAME OF PRODUCT: Protect 2000/2100 Part B MSDS DATE: 2/18/13 SECTION 1: PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: PRODUCT CODES: Protect 2000/2100 Part B 2000-B/2, 2100-B/2 MANUFACTURER: Protective Industrial Polymers ADDRESS: 7875 Bliss Parkway North Ridgeville,

More information

GPS Safety Summary Ferric sodium EDTA

GPS Safety Summary Ferric sodium EDTA GPS Safety Summary Ferric sodium EDTA Chemical Identity Name: Ferric sodium EDTA CAS number: 15708-41-5 Molecular formula: C 10 H 12 FeN 2 O 8.Na Structure IUPAC name: iron(3+) sodium 2,2',2'',2'''-(ethane-1,2-

More information

Product Stewardship Summary

Product Stewardship Summary Product Stewardship Summary Dipropyleneglycol diacrylate General Statement Dipropyleneglycol diacrylate is a colorless liquid. It is a di-functional acrylate monomer that is known for its polymerization

More information

B Supporting Information for Human Health Risk Assessment

B Supporting Information for Human Health Risk Assessment B Supporting Information for Human Health Risk Assessment 001688.OY06.06_PT083 Appendix B Table of Contents 1. Calculation of Infant Body Weight 2. Calculation of Consumption Rate of Meat for Native American

More information

EVALUATION OF POLYCYCLIC AROMATIC HYDROCARBONS IN CLAY TARGET FRAGMENTS AND SURFACE SOIL AT SHOT GUN RANGE SITES Presenter: Glenn Hoeger and Brian

EVALUATION OF POLYCYCLIC AROMATIC HYDROCARBONS IN CLAY TARGET FRAGMENTS AND SURFACE SOIL AT SHOT GUN RANGE SITES Presenter: Glenn Hoeger and Brian EVALUATION OF POLYCYCLIC AROMATIC HYDROCARBONS IN CLAY TARGET FRAGMENTS AND SURFACE SOIL AT SHOT GUN RANGE SITES Presenter: Glenn Hoeger and Brian Magee ARCADIS/Malcolm Pirnie May 11, 2011 Objectives 1.

More information

GAF Safety Data Sheet SDS # 2093 SDS Date: July 2018

GAF Safety Data Sheet SDS # 2093 SDS Date: July 2018 GAF Safety Data Sheet SDS # 2093 SDS Date: July 2018 SECTION 1: PRODUCT AND COMPANY INFORMATION PRODUCT NAME: TRADE NAME: MANUFACTURER: Timberline HD Lifetime Shingles Timberline Ultra HD Lifetime Shingles

More information

Carcinogenicity of Diesel Exhaust: Old and New Technology Diesel

Carcinogenicity of Diesel Exhaust: Old and New Technology Diesel April 5-7, 2016 Carcinogenicity of Diesel Exhaust: Old and New Technology Diesel Katherine Walker Senior Scientist Health Effects Institute Boston, MA Who is the Health Effects Institute? An independent,

More information

5 $3 billion per disease

5 $3 billion per disease $3 billion per disease Chapter at a glance Our aim is to set a market size large enough to attract serious commercial investment from several pharmaceutical companies that see technological opportunites,

More information

Accommodation and Compliance Series. Employees with Latex Allergy

Accommodation and Compliance Series. Employees with Latex Allergy Accommodation and Compliance Series Employees with Latex Allergy Preface The Job Accommodation Network (JAN) is a service of the Office of Disability Employment Policy of the U.S. Department of Labor.

More information

Texas Commission on Environmental Quality

Texas Commission on Environmental Quality Roberta L. Grant, Susan L. Santos, Mike L. Dourson, Stephanie Shirley, Neeraja K. Erraguntla, R. Jeffrey Lewis, and Nancy B. Beck Society of Toxicology, March 22-26, 2015 San Diego, CA Texas Commission

More information

Health Risk Evaluation of Site Specific Ambient Air Measurements in Garfield County, Colorado (October December 2017)

Health Risk Evaluation of Site Specific Ambient Air Measurements in Garfield County, Colorado (October December 2017) Health Risk Evaluation of Site Specific Ambient Air Measurements in Garfield County, Colorado (October December 2017) March 26, 2018 Prepared for: Garfield County Public Health 195 West 14th Street Rifle,

More information

Rutgers Environmental Health and Safety (REHS)

Rutgers Environmental Health and Safety (REHS) Rutgers Environmental Health and Safety (REHS) Program Name: Occupational Noise and Hearing Conservation Program Responsible Executive: Executive Director of REHS Adopted: June 30, 2000 Reviewed/Revised:

More information

SILICA, CRYSTALLINE (RESPIRABLE DUST)

SILICA, CRYSTALLINE (RESPIRABLE DUST) SILICA, CRYSTALLINE (RESPIRABLE DUST) CAS number: Cristobalite 14464-46-1 Quartz 14808-60-7 Tridymite 15468-32-3 Tripoli 1317-95-9 Synonyms: Chemical formula: α quartz, crystallized silicon dioxide, silica,

More information

Safety Cleaning Wipes MATERIAL SAFETY DATA SHEET. Section 1: CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

Safety Cleaning Wipes MATERIAL SAFETY DATA SHEET. Section 1: CHEMICAL PRODUCT AND COMPANY IDENTIFICATION Effective Date: 8/25/05 Supersedes: 3/01/02 Page 1 of 6 Section 1: CHEMICAL PRODUCT AND COMPANY IDENTIFICATION Product Name: Safety Cleaning Wipes For Information: 1-800-553-5340 Product Code: 8595 For

More information

GPS Safety Summary. N-(2-Methacryloxyethyl) ethylene urea (25 % solution in methyl methacrylate)

GPS Safety Summary. N-(2-Methacryloxyethyl) ethylene urea (25 % solution in methyl methacrylate) GPS Safety Summary (25 % solution in methyl methacrylate) The Product Safety Summary is intended to provide a general overview of the chemical substance in the context of ICCA Global Product Strategy.

More information

Appendix C Risk Calculations: Western Margin of Northern Plumes

Appendix C Risk Calculations: Western Margin of Northern Plumes Appendix C Calculations: Western Margin of Northern Plumes Consolidated Human Health Assessment - 2017 Table of Contents C1.0 Introduction... C-1 C2.0 Calculation of Exposure and : Young Children... C-2

More information

Managing cost considerations and access to technology for cost effective vaccine manufacture in developing countries.

Managing cost considerations and access to technology for cost effective vaccine manufacture in developing countries. Managing cost considerations and access to technology for cost effective vaccine manufacture in developing countries. Amol R. Dindokar Serum Institute of India ltd. Overview Disease Control Priorities

More information

ISO INTERNATIONAL STANDARD

ISO INTERNATIONAL STANDARD INTERNATIONAL STANDARD ISO 15197 First edition 2003-05-01 In vitro diagnostic test systems Requirements for blood-glucose monitoring systems for self-testing in managing diabetes mellitus Systèmes d'essais

More information

Setting The setting was the community. The economic study was conducted in Yokohama city, Japan.

Setting The setting was the community. The economic study was conducted in Yokohama city, Japan. Cost-benefit analysis of community based rehabilitation program using willingness to pay measured by the contingent valuation method Toida M, Takemura S Record Status This is a critical abstract of an

More information

RISK ASSESSMENT GUIDANCE FOR SUPPLEMENTAL GUIDANCE FOR INHALATION RISK ASSESSMENT SUPERFUND, PART F: Midwestern States Risk Assessment

RISK ASSESSMENT GUIDANCE FOR SUPPLEMENTAL GUIDANCE FOR INHALATION RISK ASSESSMENT SUPERFUND, PART F: Midwestern States Risk Assessment RISK ASSESSMENT GUIDANCE FOR SUPERFUND, PART F: SUPPLEMENTAL GUIDANCE FOR INHALATION RISK ASSESSMENT Michael Sivak EPA Region 2 Superfund Program Midwestern States Risk Assessment Symposium - November

More information

Material Safety Data Sheet

Material Safety Data Sheet TRAVABON * * * Section 1 - Chemical Product and Company Identification * * * Chemical Name: TRAVABON Product Use: Skin Protection Manufacturer Information Stockhausen GmbH & Co.KG Phone: ++49-2151-38-1370

More information

EUROPEAN COMMISSION DG Employment, Social Affairs and Inclusion. The Advisory Committee on Safety and Health at Work. Supplementary Opinion

EUROPEAN COMMISSION DG Employment, Social Affairs and Inclusion. The Advisory Committee on Safety and Health at Work. Supplementary Opinion Doc.819_2015_EN EUROPEAN COMMISSION DG Employment, Social Affairs and Inclusion Employment and Social Legislation, Social Dialogue Health, Safety and Hygiene at Work The Advisory Committee on Safety and

More information

Human Health Risk Assessment Overview [For the APS/OPP Roundtable]

Human Health Risk Assessment Overview [For the APS/OPP Roundtable] Human Health Risk Assessment Overview [For the APS/OPP Roundtable] Christina Swartz, USEPA Nov. 12, 2008 [Slides Courtesy of Mike Metzger, USEPA] The Risk Assessment Paradigm: The Red Book Hazard Identification

More information

10 facts you should know about carcinogens in the workplace

10 facts you should know about carcinogens in the workplace 10 facts you should know about carcinogens in the workplace Carcinogens are the time bombs of hazardous substances in the workplace. That s because many substances do not develop their deadly effect until

More information

MATERIAL SAFETY DATA SHEET

MATERIAL SAFETY DATA SHEET Emergency Phone: CHEMTREC 1-800-424-9300 For more Information Call: 1-800-537-3407 MATERIAL SAFETY DATA SHEET I. Product and Company Identification Product: MASCOBOND LO MOD, COMPONENT A Revision Date:

More information

ANNEX A. Subchapter A. GENERAL PROVISIONS * * * * *

ANNEX A. Subchapter A. GENERAL PROVISIONS * * * * * ANNEX A TITLE 25. ENVIRONMENTAL PROTECTION PART I. DEPARTMENT OF ENVIRONMENTAL PROTECTION SUBPART D. ENVIRONMENTAL HEALTH AND SAFETY ARTICLE VI. GENERAL HEALTH AND SAFETY CHAPTER 250. ADMINISTRATION OF

More information

2010 Sharing Hope Program for men

2010 Sharing Hope Program for men 2010 Sharing Hope Program for men Criteria and Application Made possible by participating sperm banks and fertility centers Program Overview Goal Cancer patients have little opportunity to save for the

More information

STANDARDIZED RADIOGENIC CANCER RISK COEFFICIENTS: A REVIEW OF THE METHODOLOGY PRESENTED IN FEDERAL GUIDANCE REPORT NO. 13

STANDARDIZED RADIOGENIC CANCER RISK COEFFICIENTS: A REVIEW OF THE METHODOLOGY PRESENTED IN FEDERAL GUIDANCE REPORT NO. 13 STANDARDIZED RADIOGENIC CANCER RISK COEFFICIENTS: A REVIEW OF THE METHODOLOGY PRESENTED IN FEDERAL GUIDANCE REPORT NO. 13 ABSTRACT Michael Boyd and Christopher Nelson, U.S. Environmental Protection, Office

More information

12 HEALTH RISK ASSESSMENT

12 HEALTH RISK ASSESSMENT 12 HEALTH RISK ASSESSMENT 12.1 Introduction The control of health risks from the exposure to any physical, chemical or biological agent is informed by a scientific, ideally quantitative, assessment of

More information

GPS Product Safety Summary

GPS Product Safety Summary Document Number: GPSSR 20 15 MAGNESIUM CHLORIDE GENERAL STATEMENT GPS summary is intended to provide a general overview of the chemical substances in context of ICCA Global Product Strategy. The information

More information

Radiation Dose Specification

Radiation Dose Specification Chapter 9 Dose Limits for Exposure to Ionizing Radiation Dose Limits for exposure to Ionizing Radiation apply to: Occupational workers Nonoccupational workers Radiation Dose Specification Equivalent Dose

More information

GPS Safety Summary Sodium hydrogensulfite

GPS Safety Summary Sodium hydrogensulfite GPS Safety Summary Sodium hydrogensulfite Chemical Identity Name: Sodium hydrogensulfite CAS number: 7631 90 5 Molecular formula: H 2 O 3 S.Na Structure IUPAC name: sodium hydrogen sulfite BASF brand names:

More information

Part 2. Chemical and physical aspects

Part 2. Chemical and physical aspects Part 2. Chemical and physical aspects 12. Chemical and physical aspects: introduction 12.1 Background information used The assessment of the toxicity of drinking-water contaminants has been made on the

More information

Development of Computational Code for Internal Dosimetry

Development of Computational Code for Internal Dosimetry Slide 1 IRPA Regional Congress, Tokyo, Japan 3 rd Asian and Oceanic Congress on Radiation Protection (AOCRP-3) Oral Session 7: Dosimetry - May 25, 2010 Development of Computational Code for Internal Dosimetry

More information

Environmental, Health and Safety

Environmental, Health and Safety Environmental, Health and Safety Codes of Practice The Environmental, Health and Safety (EHS) Codes of Practice set forth Zimmer EHS requirements for our business functions and facilities worldwide. In

More information

MATERIAL SAFETY DATA SHEET

MATERIAL SAFETY DATA SHEET MATERIAL SAFETY DATA SHEET 1. CHEMICAL PRODUCT AND COMPANY INFORMATION Manufacturer Name And Address Hospira Inc. 275 North Field Drive Lake Forest, Illinois USA 60045 Emergency Telephone CHEMTREC: North

More information

Material Safety Data Sheet

Material Safety Data Sheet * * * Section 1 - Chemical Product and Company Identification * * * Product Use: All purpose skin protection Company Information Evonik Stockhausen, LLC Non-Emergency # 800-242-2271 2401 Doyle Street Greensboro,

More information

: POLYSHIM II.090X.375-1/16 SHIM 1000FT/CS

: POLYSHIM II.090X.375-1/16 SHIM 1000FT/CS SECTION 1 - PRODUCT IDENTIFICATION / PREPARATION INFORMATION Product Information Trade name Product code : : 7242YA3760 Supplier : Tremco Canada division 220 Wicksteed Avenue Toronto, ON M4H 1G7 Telephone

More information

SAFETY DATA SHEET. Natural Guard Neem RTU. Effective Date: 23-Mar PRODUCT AND COMPANY IDENTIFICATION

SAFETY DATA SHEET. Natural Guard Neem RTU. Effective Date: 23-Mar PRODUCT AND COMPANY IDENTIFICATION 1. PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: Neem RTU EPA Reg. No.: 70051-13-7401 COMPANY IDENTIFICATION: Bonham, TX. 75418 2. HAZARDS IDENTIFICATION 2.1. Classification of the substance or mixture

More information

Collyrium Eye Wash Solution MATERIAL SAFETY DATA SHEET. Section 1: CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

Collyrium Eye Wash Solution MATERIAL SAFETY DATA SHEET. Section 1: CHEMICAL PRODUCT AND COMPANY IDENTIFICATION Effective Date: 11/14/05 Supersedes: 1/29/01 Page 1 of 6 Section 1: CHEMICAL PRODUCT AND COMPANY IDENTIFICATION Product Name: Collyrium Eye Wash Solution For Information: 1-800-553-5340 Product Code(s):

More information

Investor Presentation

Investor Presentation ASX:THC B u i l d i n g a M e d i c i n a l C a n n a b i s B u s i n e s s Investor Presentation November 2017 DISCLAIMER The material in this presentation (material) is not and does not constitute an

More information

MANGANESE & HEALTH: A BALANCE OF STORIES

MANGANESE & HEALTH: A BALANCE OF STORIES MANGANESE & HEALTH: A BALANCE OF STORIES November 2014 1 Overview 2. Analysis of Literature on Carcinogenicity & Mutagenicity 1. Uses of inorganic Mn substances 3. Research to better understand Carcinogenicity

More information