ADULT OXYGENATORS CATALOGUE
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1 ADULT OXYGENATORS CATALOGUE
2 A solution for every need Clinical flexibility Optimized priming High performance gas exchange Low contact surface Low GME activity Easy to set up and debubbling
3 The path of biocompatibility Phosphorylcoline or PC is the predominant lipid headgroup found in the outer layer of cell membranes. PC has a natural affinity for water and binds water tightly around itself. As a result, the outer layer of the cell membrane does not promote clots formation (thrombosis). low thrombogenic low inflammatory stable resistant to bacterial adhesion resistant to protein deposition PHOSPHORYLCHOLINE COATING S U R FA C E FOREIGN S U R FA C E Roberto Cavicchioli Eurosets all rights reserved FOREIGN ALKALINE CHAINS SPREAD ACROSS THE SURFACE YELDING A STABLE COATING THROUGH HYDROPHOBIC INTERACTIONS ZWITTERIONIC PC GROUPS EXPRESSED OUTWARDS FROM THE SURFACE LAYER OF HYDRATATION AROUND PC - WITH A COATED SUBSTRATE THE BLOOD THEREFORE SEES A LAYER OF WATER BLOOD\BODY FLUID CONTACT LAYER
4 OXYGENATOR MODULE TECHNICAL FEATURES purging line cardioplegia blood outlet arterial blood outlet H.E. water in/out venous blood inlet
5 ALONE OXYGENATOR MODULE Priming volume: 190 ml Contact surface area: 1,35 m 2 Max blood flow rate: 7,0 l/min Innovative Heat Exchanger Heat Exchanger surface area: 0.08 m 2 H.E. Performance Factor η = 0.64 (@ 4 l/min) Coating: PC phosphorylcholine O2T (cc/min) O2T vs Qb 400,0 350,0 300,0 250,0 200,0 150,0 100, CO2T (cc/min) CO2T vs Qb 350,0 300,0 250,0 200,0 150,0 100, Performance Factor 1,00 0,90 0,80 0,70 0,60 0,50 0,40 0,30 0,20 0,10 H.E. Performance Factor vs Qb (Water Flow 10 l/min) 0, AMG OXYGENATOR MODULE Priming volume: 220 ml Contact surface area: 1,81 m 2 Max blood flow rate: 8,0 l/min Innovative Heat Exchanger Heat Exchanger surface area: 0.08 m 2 H.E. Performance Factor: η = 0.64 (@ 4 l/min) Coating: PC phosphorylcholine O2T vs Qb O2T (cc/min) CO2T (cc/min) CO2T vs Qb Performance Factor H.E. Performance Factor vs Qb (Water Flow 10 l/min)
6 SINGLE VENOUS HARDSHELL RESERVOIR Clinical flexibility Low contact surface Agile PC Coating High volume Capacity Low GME activity Easy-to-use holder Max volume capacity 4600 ml (approx) Max operating level 4500 ml (approx) Min. operating level 200 ml (approx) Venous Filter Pore Size: 80 μm Cardiotomy Filter Pore Size: 40 μm Cardiotomy reservoir ready for vacuum (equipped with over-under safety valve) Connectors: 6 x 1/4 1 x POS Lock 1 x 3/8 2 x Luer Lock 1 x POS Lock - Luer Lock 1 x Unfiltered Luer Lock Conical dispenser to reduce suckers microembolic activity
7 DUAL CHAMBER VENOUS RESERVOIR LIPIDS AND LEUCOCYTES REDUCER Despite improvements in cardiopulmonary bypass (CPB) brain injury remains a significant sequela of cardiac surgery. Cardiopulmonary bypass is associated with an inflammatory reaction that involves activation of plasma proteins and cells. Activation of leukocytes, in particular neutrophils, directly contributes to issue and organ injury. CARDIOTOMY Capacity (activated blood section): 1800 ml (approx) Two steps lipid-leukocytes depletion: Multilayer cascade filtration (for lipids and leukocytes) Supernatant separator (lipids only) VENOUS RESERVOIR supernatant separator level Capacity (non activated blood section): 3200 ml (approx) Filter Pore Size: 80 μm Ready for vacuum (equipped with over-under safety valve) Connectors: 2 x 1/4 1 x 3/8 2 x Luer Lock 1 x POS Lock - 1/4 1 x Luer Lock unfiltered 1 x 1/4 Dedicated intracavitary port LIPIDS REDUCTION [%] Cardiotomy ready for vacuum (equipped with over-under safety valve) Connectors: 2 x 1/4 1 x 3/8 2 x Luer Lock 1 x POS Lock - Luer Lock 1 x 1/4 Cell Saver outlet Line TIME (min) LAB TEST Conical dispenser to reduce suckers microembolic activity WBC s REDUCTION [%] TIME (min) LAB TEST
8 ordering guide COMBINE OXYGENATOR MODULE RESERVOIR A.L.ONE (1.35 m 2 ) AG5000 (N 3 pcs/pack) SINGLE VENOUS HARDSHELL RESERVOIR SKIPPER EU5007 (N 2 pcs/pack) (Oxy Module PC Coating only) SKIPPER AG5007 (N 2 pcs/pack) DUAL CHAMBER VENOUS RESERVOIR LIPIDS AND LEUCOCYTES REDUCER REMOWELL AG5015 (N 1 pcs/pack) AMG MODULE(1.81 m 2 ) AG5012 (N 3 pcs/pack) AMG Single Chamber AG5011 (N 2 pcs/pack) AMG Leuko-Lipid AG5025 (N 1 pcs/pack) EU2331 (N 1 pcs/pack) EU2054/P (N 1 pcs/pack) Holder (Oxy Gas Module + Reservoir) Holder for A.L.ONE/AMG gas module *REMOWELL REFERENCES The diffuse brain damage (DBD) after cardiac operation is reported as a frequency within a range of between 20% and 80%. karl Gunnar Engstrom. The embolic potential of liquid fat in pericaldial suction blood, and its elimination. Perfusion 2003; 18:69-74 Current estimates indicate that > 50% of patients who undergo to CPB have neurological or neuropsychological deficits during the first week after surgery, 10% to 30% have long-term or permanent deficits, and 1% to 5% experience severe disability or die. William R. Brown et al. Longer duration of cardiopulmonary bypass is associated with greater numbers of cerebral microemboli. Stroke2000; 31: The scavenging of pericardial suction blood is a potential mayor source of lipid emboli during cardiopulmonary by pass. Robert F. Brooker et al. Cardiotomy Suction: a Major Source of Brain Lipid Emboli during Cardiopulmonary bypass. Ann Thorac Surg 1998; 65: Lipid particles in the side range of 10 μm to were characterized in shed mediastinal blood, until 300,000 particles per milliliter of blood were found. Atli Eyjolfsson, Henrik Jonsson et al. Charatcterization of Lipid Particles in Shed Mediastinal Blood. Ann Thorac Surg 2008; 85: Embolization of lipids is not a phenomenon restricted to the brain, but affected other organs which kidneys1, spleen1 and lung2. 1 Henrik Jonsson et al. Differential Distribution of Lipid Microemboli After Cardiac Surgery. Ann Thorac Surgery 2006; 81: AJ de Vries et al. The rationale for fat filtration during cardiac surgery. Perfusion 2002; 17: Activation of the systemic inflammatory response during CPB has been a mayor problem for clinicians because of the potenzial deleterious effect on organs such as the heart, brain, lung, kidneys. one strategy may be the use of leukocyte-depleting filters. Oliver Warren et al. The effect of various leukocyte fitration strategyes in cardiac surgery. Eur J Cardiothorac Surg 2007; 31: Shalini Boodram et al. Use of Leukocyte-depleting Filters During Cardiac Surgery with Cardiopulmonary bypass: A Review. JECT 2008; 40: Rev. 02 / 2017 Prodotto da Manufactured by Fabriquè par Hersteller Fabricado por Eurosets s.r.l. Strada Statale 12, n Medolla (MO) Italy Tel: Fax: info@eurosets.com eurosets.com Distribuito da Distributed by Distribuè par Vertrieb Distribuido por Copyright 2017 by Eurosets S.r.l. - Catalogue, products, pictures may differentiate from the actual product appearance. Specifications are subject to change without prior notice.
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