Burn Pathology.
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1 Burn Pathology
2 While there is life, there s hope - Theocritus (3 rd Century B.C.)
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4 Cutaneous Burn Multi-Organ System Problems
5 Immobilization and Bed Rest Effects
6 Organ System Involvement Integumentary System
7 Hypertrophic versus Keloid Scars
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19 Heat Tolerance in Patients with Extensive Healed Burns Ben-Simchon C, et al. Plast Reconst Surg 1981;67: Austin KG, et al. J Burn Care Rehabil 2003;24:9-14
20 Cutaneous Sensory Changes Following Burn Injury Ward RS, et al. J Burn Care Rehabil 1991;12: Malenfant, et al. Pain 1998; 77:
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22 Organ System Involvement Respiratory System
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25 Organ System Involvement Cardio-vascular System
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28 Pressure Gradients Hydrostatic pressure Oncotic pressure
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34 Cardio-vascular Changes Decrease cardiac output Decreased stroke volume Reduced MAP Increased RHR Increased HR with exercise
35 Hematolgic Effects Hemoconcentration Decreased intravascular fluid Increased hematocrit Increased blood viscosity Wound conversion Thrombotic susceptibility
36 Musculo-Skeletal System Muscle protein metabolism Muscle atrophy
37 Strength loss from muscle disuse 3% per day 20% per week 50% in 3 5 weeks Halar & Bell, 1990
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41 Heterotopic Ossification Etiology Calcium mobilization from immobilization High protein intake Microtrauma >20% total body burn Sepsis
42 Heterotopic Ossification Incidence 0.1% - 3.3% (Retrospective studies) 13.6% - 23% (Prospective studies)
43 Heterotopic Ossification Location Highest elbow, shoulder, hip Other knee, ankle, wrist, hand, TMJ, cricoarytenoid joint Full-thickness injuries Areas that remain unhealed for prolonged period of time May appear in areas other than burn
44 Heterotopic Ossification Symptoms Pain with range of motion Quality of pain change Point-specific pain Limitation of motion Bony end feel
45 Heterotopic Ossification Prognosis good
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47 Additional Musculo-Skeletal Problems Osteoporosis Fractures Joint dislocations Septic arthritis Amputations Bone spurs Bone retardation
48 Peripheral Neuropathy Etiology 1. Polyneuropathy Uncertain May be neurotoxin > 20% total body burn
49 Peripheral Neuropathy Etiology 2. Local neuropathy Direct thermal injury rare Management injury due to pressure Improper position in bed or operating room Compression from edema, bandages, or tourniquet Entrapment secondary to HO Injections
50 Peripheral Neuropathy Incidence 15% - 29% Prospective studies
51 Peripheral Neuropathy Location Brachial plexus Ulnar nerve Peroneal nerve Median nerve*
52 Peripheral Neuropathy Symptoms Muscle paralysis/weakness Paresthesias/Anesthesia Prognosis: Spontaneous recovery
53 Burn Pain Worst experience for human Continues until all wounds are healed Greatest obstacle to rehabilitation Non-reproducible
54 Pain Management Realize patient has pain Resist taking confrontations personally Allow patient to express pain/emotions Provide for rest periods Encourage patient participation
55 Treatment Interventions Sensory reappraisal Patient preparation/education Time pain medication with therapy treatment
56 Pain is temporary, Pride is forever!
57 Psychologic Issues
58 Pain is inevitable, Suffering is optional!
59 Specialized Senses Opthalmic Audiologic
60 Marjolin s Ulcer (1828) Latent period: years Etiology: Chronic local infection or irritation Delayed healing Predilection: Extremities & joint creases
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