SOUTH EASTERN KENYA UNIVERSITY UNIVERSITY EXAMINATION 2015/2016 FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF PUBLIC HEALTH

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1 SOUTH EASTERN KENYA UNIVERSITY UNIVERSITY EXAMINATION 2015/2016 FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF PUBLIC HEALTH HPH 102: MEDICAL MICROBIOLOGY DATE: 7/12/2015 TIME:10:30-12:30PM INSTRUCTIONS 1. Answer the questions as per the instructions under each part. 2. Part I : Multiple choice questions (20 Marks) 3. Part II :short answer questions (20 Marks) 4. Part III : Long answer/essay questions (30Marks) 5. All questions must be answered on the examination booklet except for part I 6. Enter your registration number and NOT your name in the space provided on your answer booklet 7. Each candidate must sign in the examination attendance list 1

2 PART I: MULTIPLE CHOICE QUESTIONS (MCQS). Choose one correct answer (20MARKS) 1. One of the following is a microscopical feature of the Streptococcus pneumoniae A. Gram negative B. It s flagellated C. It s elongated (lancet-shaped) Diplococcus D. It s non capsulated 2. Is a toxin produced by Clostridium Perfringens:- A. Toxin type A B. Toxin type B C. Toxin type Z D. Theta toxin 3. It is an antigenic structure that is found in the envelopes of Salmonella spp A. Vi antigens B. H antigens C. O antigens D. K antigen 4. Chlamydia psittaci can cause A. Paratrachoma B. Pneumonia or mild influenza like illness C. Nongonococcal urethritis D. Cervicitis and pelvic inflammatory disease 5. Is a biological importance of fungal spores A. Rapid identification (also helps with classification) B. Source of inocula for human infection C. Source of inocula for contamination D. Allows fungus to survive periods of adversity. 6. Tinea cruris refers to dermatophytosis of the A. Foot, toes and fingers B. Proximal medial thighs, perineum and buttocks. C. Beards and skin D. Scalp and skin 2

3 7. Is a fungus known to cause mycetoma A. Actinomadura madurae B. Streptomyces pelletieri C. Periellidium boydii D. Nocardia brasiliensis 8. Is a member of the Paramyxoviruses A. Alpha viruses B. Respiratory Syncytial virus C. Smallpox D. Measles virus 9. One of the unique characteristics of mycoplasmas is that: A. Have a cell wall B. Lack a cell wall C. Only survive in a host cell D. Have plenty of hemoglobin in the granules 10. Which of the following bacteria is spore forming:- A. Bacillus anthracis B. Mycobacterium tuberculosis C. Treponema pallidum D. Brucella melitensis 11. Gram positive bacteria include:- A. Neisseria gonorrhea, Corynebacterium diptheriae, Hemophilus influenza B. Corynebacterium diptheriae, Hemophilus influenza, Bacillus anthracis C. Corynebacterium diptheriae, Bacillus anthracis, Staphylococcus aureaus D. Bacillus anthracis; Staphylococcus aureaus; Treponema pallidum 12. Which scientist discovered the theory of fermentation:- A. William Budd B. Joseph Lord Lister C. Robert Koch D. Louis Pasteur 13. Two methods of disinfection are:- A. Heat and chemical disinfection B. Antiseptic and chemical disinfection C. Incineration and chemical disinfection D. Incineration and heat 3

4 14. Which of the following is the most frequent cause of blood transfusion associated hepatitis:- A. Hepatitis A virus B. Hepatitis B virus C. Hepatitis C virus D. Hepatitis D virus 15. Yellow fever is caused by:- A. Virus B. Fungi C. Protozoa D. Bacteria 16. The fungal infection of the scalp is :- A. Tinea capitis B. Tinea corporis C. Tinea pedis D. Tinea versicolor 17. Bacteria which grows in complete absence of oxygen are called:- A. Aerobes B. Anaerobes C. Facultative aerobes D. Facultative anaerobes 18. Which of the following organisms causes relapsing fever and is transmitted by an anthropod:- A. Treponema B. Borrelia C. Leptospira D. Mycobacteria 19. A disease that affects many people in different countries is known as : A. A sporadic episode B. Pandemic C. Endemic D. Epidermic 20. Indicate true or false for the following statements about Pseudomonas aeruginosa; i. It is Oxidase positive ii. Can grow in tap water 4

5 PART II: SHORT ANSWER QUESTIONS (SAQS). Answer any four of the following questions (20MARKS) 1. State the following virulence factors mode of activity (1 mark each) i. Coagulase ii. Lytic toxins iii. Staphylokinase iv. Capsule v. Pili 2. Explain the significance of haemolytic activity of Streptococci and the three categories (5 mks) 3. Outline two ways in which women become susceptible to candidiasis (5 marks) 4. State five preventive measures of anthrax (5 marks) 5. Outline the steps of viral replication cycle (5 marks) PART III: LONG ANSWER QUESTIONS (LAQS). Answer any two of the following questions (30MARKS) Question one i. Differentiate between gram positive and gram negative bacteria (5 marks) ii. Explain the chain of infection of Syphilis (10 marks) Question two i. Explain five ways through which viruses are transmitted to man giving one example for each (10 marks) ii. Outline five differences between viruses and bacteria (5 marks) Question three i. State five ways in which man can prevent fungal infections (5 marks) ii. Explain the chain of infection of Cryptococcus neoformans (10 marks) 5