DENTAID S MISSION. Advancing through research

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1 VADEMECUM

2 DENTAID S MISSION Dentaid, founded in 1980, is a pioneer oral research company whose goal is to improve oral health throughout society, by providing the best scientifically-backed solutions to consumers around the globe. Our commitment to research and innovation and our strong working relationship with dental and pharmaceutical professionals and major European and American universities have contributed to our status as world-wide leaders. Advancing through research We are one of the few European laboratories specialised in the microbiological research of dental biofilms. By combining state-ofthe-art technology and highly qualified staff, we are able to consistently guarantee quality levels in all of our brands. 2

3 In search of new challenges To cover the population s oral hygiene needs, we are constantly working to innovate by creating new products and improving our existing ones. To innovate, our advanced facilities are exclusively devoted to research and development. Our business strategy is based on a strong commitment to continuous research and development of high quality, innovative products. Through this commitment, we have become what we are today: a multinational leader in oral health. DENTAID is present in more than 60 countries EUROPE Andorra Belgium Bulgary Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Hungary Iceland Ireland Italy Latvia Lithuania Luxembourg Malta The Netherlands Norway Poland Portugal Romania Russia Slovakia Slovenia Spain Sweden Switzerland Ukraine United Kingdom AMERICA Bolivia Chile Colombia Dominican Republic Guatemala Mexico Paraguay Peru Uruguay ASIA Iran Iraq Japan Jordan Kazakhstan Kingdom of Bahrain Kingdom of Cambodia Kuwait Lebanon Malaysia Myanmar Qatar Saudi Arabia Singapore United Arab Emirates AFRICA Algeria Benin Burkina Faso Egypt Libya Mali Morocco Niger Togo Tunis Mauritus Gabon Senegal subsidiaries OCEANIA New Zeland 3

4 INDEX CHLORHEXIDINE + CPC 4

5 TOOTHBRUSHES Toothbrushes Monotip Attack zone disrupts even the most resistant dental biofilm. Protective cap Keeps filaments together and in optimal conditions while isolating them from external contact. Filaments Made of end-rounded, textured Tynex preventing damage to enamel and gum. Brushing surface Different formats for accessing interdental spaces in every situation. Brush head Small and rounded for easy brushing and better access to hard-to-reach areas. Handle Ergonomic and adaptable, can be bent to the form of your mouth. 5

6 TOOTHBRUSHES SOFT Normal brush head with soft filaments MEDIUM Normal brush head with medium strength filaments HARD Normal brush head with hard filaments JUNIOR Child-size brush head with soft filaments ACCESS SOFT Small brush head with soft filaments ACCESS MEDIUM Small brush head with medium strength filaments GINGIVAL For gently cleaning delicate gums SENSITIVE For gently cleaning sensitive teeth ULTRASOFT ORTHODONTIC Specifically designed for cleaning fixed orthodontic appliances Very gentle cleaning for cases of extreme sensitivity ACCESS ORTHODONTIC SURGICAL Small brush head specifically designed for cleaning fixed orthodontic appliances Extremely gentle cleaning after surgical interventions PERIO Specific cleaning for periodontal treatments or wide spaces MONOTIP For efficiently cleaning braces, prostheses and implants 6

7 IMPLANT implant The most complete and specialised product range for hygiene, care and protection of dental implants Innovation applied to implant hygiene Cutting edge toothbrushes, designed specifically for disrupting oral biofilm around implants with the utmost precision, penetrate the peri-implant sulcus, to mechanically break up the biofilm, enhancing the effects of antimicrobial agents Special situations IMPLANT ANGULAR Indicated for cleaning the area where implants and gums meet Small brush head that with soft Tynex filaments efficiently reaches areas around implants that are normally hard to clean. Provides easy access to lingual surfaces of the anterior and posterior sections of the dental arches. IMPLANT SULCULAR Indicated in people with implants, prostheses and periodontsal problems Small, narrow and linear brush head with soft Tynex filaments arranged in two rows. Specifically indicated for cleaning the gingival and/or peri-implant sulcus. Indicated for gently and thoroughly cleaning mouths with implans Indicated for cleaning implants and prostheses IMPLANT BRUSH Small, rounded brush head for daily brushing, care and hygiene in people with dental implants. Extra-soft Tynex filaments provide gentle, but deep, cleaning of gums when mucogingival problems are present. IMPLANT MONOTIP Small brush head. Tynex filaments arranged in a monotuft. Designed specifically to access very small spaces that require maximum cleaning precision of implant-supported prostheses. 7

8 DENTAL FLOSS & TAPE dental floss & tape WAXED DENTAL FLOSS WAXED DENTAL TAPE WITH FUORIDE AND MINT Waxed dental floss Easy-glide cleaning. Eliminates interdental bacterial plaque. Ideal for creating good flossing habits. Waxed dental tape with fluoride and mint Cleaning that strengthens enamel. Eliminates interdental bacterial plaque. Fluoride strengthens enamel. Contains sodium fluoride. SOFT WAXED DENTAL FLOSS Soft waxed dental floss with fluoride and mint Gentle cleaning in people with braces, implants and prosthetics. Eliminates interdental bacterial plaque. Textured floss expands when in contact with saliva. Contains sodium fluoride. 8

9 WHITENING whitening Effectively whitens and prevents dental sensitivity Repairing and Whitening action Hydroxyapatite Nanoparticles Natural tooth element that integrates and forms a protective, wash-resistant coating. - Fill irregular tooth surfaces - Repair tooth enamel, making surface smoother and brighter. DENTAID technology - Form a protective coating to prevent dental sensitivity nanorepair Toothpaste Mouthwash Hydroxyapatite Nanoparticles Repair dental enamel for a smoother and brighter surface. 0.45% % Sodium monofluorophosphate Polyvinylpyrrolidone (PVP) Reinforces enamel. Removes stains from the surface of tooth enamel and prevents their formation. 1.10% 0.172% Tetrapotassium pyrophosphate Sodium tripolyphosphate Sodium hexametaphosphate Delay or prevent calculus formation: crystallization of bacterial plaque (oral biofilm). Remove stains and prevent their formation. Perlite Polishes and smoothes dental enamel without damaging it. Gives surface a smoother and brighter finish. Restores the natural shine of teeth. _ Sizes 100ml 500ml REFERENCES: 1. Dentist-controlled clinical efficacy study. Barcelona, Ribeiro S. VITIS Whitening. A clinical study. Poster communication at XV Congresso Associaçao Portuguesa de Higienistas Orais In vitro study of whitening and stain prevention on teeth and on hydroxyapatite discs. Dentaid Research Center,

10 ANTICARIES anticaries Prevents the onset of caries and protects against dental erosion The first anticaries product that repairs, strengthens and remineralises tooth enamel by way of 3 mechanisms of action Repairs damaged enamel Forms an erosion-resistant protective layer Strengthens and remineralises enamel DENTAID technology nanorepair + Fluoride + Xylitol Toothpaste Mouthwash Hydroxyapatite Nanoparticles Repair and strengthen enamel, thereby preventing tooth decay. Form an erosion-resistant coat when ph is low. 0.45% % Sodium monofluorophosphate Remineralises enamel and prevents dental caries. 1.10% 0.172% Xylitol Moisturises the oral cavity and prevents tooth decay. Provides a fresh feeling throughout the mouth. 10% 3.3% Sizes 100ml 500ml REFERENCES: 1. Soler A., Massoli A., León R., Blanc V. In vitro evaluation of the remineralising effect of a dentifrice containing hydroxyapatite nanoparticles, sodium monofluorophosphate and xylitol. Internal study conducted at Dentaid Research Center,

11 SENSITIVE sensitive Relieves sensitive teeth. Repairs and protects enamel. Helps to prevent tooth sensitivity Protects gums Reinforces enamel Daily use. Starts working from the first application Toothpaste Mouthwash Hydroxyapatite Nanoparticles Form a protective coat to prevent dental sensitivity. 0.45% % Potassium nitrate Sodium fluoride Pro-vitamin B5 (Panthenol) Allantoin Vitamin E Prevents tooth sensitivity. Reinforces enamel. Protects gums. Promotes healthy gums. Protects gums. 5.00% 1450 ppm 1.0% 0.1% 0.30% 1.00% 226 ppm 0.5% 0.10% Sizes 100ml 500ml REFERENCES: 1. Gil Loscos, F.; Iborra, I.; Marti, M.; Alpiste, F. In vitro study of a hydroxyapatite nanoparticle-based toothpaste. Research Team at the University of Valencia. Poster published at the Spanish Society of Periodontology 2012 Meeting. 2. Clinical trial to evaluate the efficacy and tolerability of a desensitising toothpaste. Dentist-controlled independent study Ohta, K., Kawamata, T., Ishizaki T., Hayman, R. Occlusion of Dentinal Tubules by Nano-Hydroxyapatite. J Dent Res, Vol.86, Special Issue A(New Orleans Abstracts), 2007; SANGI Co., Ltd, Tokyo, Japan 11

12 ORTHODONTIC Reinforces enamel Keeps gums healthy Reduces plaque (biofilm) build-up Prevents bad breath Helps keep braces clean VITIS ORTHODONTIC KIT Cetylpyridinium chloride Sodium fluoride Aloe Vera Allantoin Reduces biofilm accumulation. Reinforces enamel. Promotes healthy gums. Promotes healthy gums. Toothpaste 1450ppm 0.126% 0.10% Mouthwash 226ppm 0.10% VITIS orthodontic wax Creates a protective coating that protects against rubbing caused by orthodontic appliances. VITIS orthodontic tablets Prevent plaque buildup and bad odour. Get rid of stains from tea, coffee, smoking. Do not harm metallic parts of orthodontic appliances. Sizes 100ml 150ml/500ml 2 units 32 units REFERENCES: 1. Herrera D, Pérez L, Escudero N, Alonso B, Serrano J, Martin C, Sanz M. Evaluation of Cetylpyridinium chloride. Formulations in orthodontic patients: Periodontal outcomes. Comunication at IADR Munich Sept

13 GINGIVAL Reduces plaque (biofilm) build-up For delicate gums Reinforces enamel Protects gums VITIS GINGIVAL KIT 30 ml VITIS gingival mouthwash 15 ml VITIS gingival toothpaste VITIS gingival toothbrush Toothpaste Mouthwash Cetylpyridinium chloride Sodium fluoride Reduces biofilm accumulation. Reinforces enamel. 1450ppm Pro-vitamin B5 (Panthenol) Protects and gums. 1% 0.5% Zinc lactate Increases the substantivity of CPC, lengthening its activity. 0.25% 0.14% Sizes 100ml 150ml/500ml REFERENCES: 1.García V, Rioboo M, Serrano J, Herrera D, SANZ M. Plaque Inhibitory Effect of a Cetyl-Pyridinium Chloride Mouthrinse. Journal of Dental Research 2008; 87 (special issue). 2.Sanz M, Herrera D. Clinical and microbiological efficacy on an antimicrobial mouthrinse containing 0,05% CPC in patients with gingivitis. International Journal of Dental Hygiene (accepted sept 2010) 13

14 INTENSIVE CARE INTENSIVE CARE 0.12% CHLORHEXIDINE + CPC FIGHTS ORAL BIOFILM PERIO AID INTENSIVE CARE MOUTHWASH Before and after in-office dental care For excessive dental plaque (oral biofilm) formation PERIO AID INTENSIVE CARE GEL Before and after in-office dental care For excessive dental plaque (oral biofilm) formation For topical use Can be combined with a chlorhexidine-based mouthwash as it does not contain anionic agents which may alter the efficacy of chlorhexidine PERIO AID INTENSIVE CARE SPRAY Before and after in-office dental care For excessive dental plaque (oral biofilm) formation When brushing is painful and/or other methods are difficult to perform For cleaning backmost areas of the mouth Mouthwash Spray Gel Chlorhexidine digluconate Efficiently fights dental biofilm. 0.12% 0.12% 0.12% Cetylpyridinium chloride Reduces biofilm accumulation. Sizes 150ml/500ml 5000ml 50ml 75ml REFERENCES: 1. Herrera D., Roldán S., Santacruz I., Santo S., Masdevall M., Sanz M. Differences in antimicrobial activity of four commercial 0.12% chlorhexidine mouthrinse formulations: an in vitro contact test and salivary bacterial counts study. Journal of Clinical Periodontology 2003; 30: Blanc V., Isabel S., Sánchez MC., Llama-Palacios A., Herrera D., Sanz M., León R. Characterization and application of a flow System for in vitro multispecies oral biofilm formation. Journal of Periodontal Research 2014 Jun: 49(3):

15 ACTIVE CONTROL ACTIVE CONTROL CHLORHEXIDINE + CPC ACTIVELY CONTROLS ORAL BIOFILM LONG TERM USE PERIO AID ACTIVE CONTROL MOUTHWASH After in-office dental care For excessive dental plaque (oral biofilm) formation When proper brushing and oral hygiene are not possible Chlorhexidine digluconate Cetylpyridinium chloride Sizes Efficiently fights dental biofilm. Reduces biofilm accumulation. Mouthwash 150ml/500ml REFERENCES: 1. Evaluation of the antimicrobial activity of chlorhexidine rinses on multispecies oral biofilms. Internal study, conducted in DENTAID Research Center Quirynen M., Soers C., Desnyder M., Dekeyser C., Pauwels M., van Steenberghe. A cetyl pyridinium chloride / chlorhexidine mouthrinse during maintenance phase after initial periodontal therapy. D. J Clin Periodontol 2005; 32: Escribano M., Herrera D., Morante S., Teughels W., Quirynen M., Sanz M. Efficacy of a low-concentration chlorhexidine mouth rinse in non-compliant periodontitis patients attending a supportive periodontal care programme: a randomized clinical trial. Clin Periodontol 2010; 37:

16 INTERPROXIMAL CLEANING INDICATIONS Cleans all spaces for complete oral hygiene Interdental spaces Implants Diastema Orthodontic Fixed appliances prosthesis Furcal areas Quality and Hygiene Plastic coated wire that protects teeth, gums and dental implants High quality black and white Tynex filaments for detecting plaque and bleeding The cap protects the brush and guarantees optimal hygiene after use Flexibility The head and the handle are flexible and do not have any memory effect allowing easier access to every interdental space Plastic lined neck for added protection, flexibility and anchoring of the wire Specific design Angled head for better access to posterior spaces Longer and rigid handle Comfort and precision Anti-slip groove for precision and comfort during brushing 16

17 INTERPROXIMAL CLEANING SIZES RANGE Cleans all spaces for complete oral hygiene SAMPLING BOX Cetylpyridinium chloride Sodium fluoride Zinc lactate Allantoin Sizes Reduces biofilm accumulation. Reinforces enamel. Increases the substantivity of CPC, lengthening its activity. Promotes healthy gums. Gel 0.3% 1450ppm 0.14% 0.10% 20ml REFERENCES: 1. Schmidt B, Jentsch H. Comparison Between Two Interproximal Cleaning Procedures in Periodontitis Patients: A Six-month, Single-blind, Randomised Controlled Clinical Trial. Oral Health Prev Dent. 2015;13(3): *ISO 16409: International standard for manual interdental brushes 17

18 Reduces dental biofilm build up Control bad breath Chlorhexidine digluconate Efficiently fights dental biofilm. Toothpaste Mouthwash Spray Tongue cleaner Cetylpyridinium chloride Sodium fluoride Zinc Lactate Reduces biofilm accumulation. Reinforces enamel. Increases the substantivity of CPC, lengthening its activity. 1450ppm 0.14% 0.14% 0.14% Removes the dental biofilm that forms on the tongue surface. Xylitol Moisturises oral cavity and caries prevention. 10% Sizes 75ml 150ml/500ml 15ml REFERENCES: 1.S. Roldán, E.G. Winkel, D. Herrera, M. Sanz, A.J. van Winkelhoff. The effects of a new mouthrinse containing chlorhexidine, cetylpyridinium chloride and zinc lactate on the microflora of oral halitosis patients: a dualcentre, double-blind placebo-controlled study. J Clin Periodontol 2003; 30: MOISTURES THE ORAL CAVITY Daily use toothpaste and mouthwash that helps moisturise the oral cavity Gel for patients requiring increased moisture STIMULATES THE NATURAL PRODUCTION OF SALIVA Spray to stimulate natural production of saliva Betaine Sodium fluoride Aloe Vera Xylitol Allantoin Malic acid Buffer system Long-lasting moisturiser and osmotic protective agent. Reinforces enamel. Promotes healthy gums. Moisturises oral cavity and caries prevention. Promotes healthy gums. Stimulates natural saliva production; does not erode enamel. Consisting of phosphate ions, keeps ph from dropping below 5.5 while tablets dissolve in the mouth, preventing enamel erosion. Toothpaste Mouthwash Gel Spray 4.0% 1.33% 1.0% 1450ppm 226ppm 15ppm 226ppm 10.0% 3.30% 10.0% 10.0% 0.10% 0.10% 1.0% Sizes 75ml 500ml 50ml 15ml REFERENCES: 1. ADSP da Mata, DN da Silva Marques, JML Silveira, JROF Marques, ET de Melo Campos Felino, NFRPM Guilherme. Effects of gustatory stimulants of salivary secretion on salivary ph and flow: a randomized controlled trial. Oral Diseases (2009) 15,

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