Brånemark System Facts & Figures

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1 Brånemark System Facts & Figures Brånemark System is synonymous with the revolution in dental care by the introduction of safe and effective implants. Professor Brånemark, its inventor, always put the patient in focus and secured the outcome by meticulous clinical evidence. The first patient was treated in 1965, and Brånemark System is today the most used and documented implant system on the market. More than 1000 articles, published in scientific journals, report on the use and the excellent outcome of Brånemark System implants. A dominating position In a published review 6 on prospective, long-term clinical studies, Brånemark System had a dominating position; more than 50% of the reviewed articles reported on studies performed with Brånemark System implants. Prospective long-term clinical studies The reference tables below shows an overview of some of the Brånemark System long-term studies with at least 5 years of follow-up. The references are divided according to indication areas; i.e., full-arch, partial and single-tooth replacements.

2 Table 1. Overview of cumulative survival/success rates () in full arch replacements. Full arch replacements Prosthesis F-up Attard NJ & Zarb GA 2004 OD 15 y 96% 100% Attard NJ & Zarb GA 2004 FB 20 y 87% 84% Bergendal T & Engquist B 1998 OD 5 y 100% 75% - - Eliasson A et al 2000 FB 5 y 99% Ericsson I et al 2000 FB 5 y 100% Ekelund JA et al 2003 FB 20 y 99% - 100% - Friberg B et al 1997 FB 5 y 100% 87% 97% Hemmings KW et al 1994 OD 5 y 93% Jemt T 1994 FB 5 y - 92% - 96% Jemt T et al 2002 FB 5 y - 93% - 95% Naert I et al 1998 Naert I et al 2004 OD OD 5y 10 y 99% 99% Watson RM et al 1997 OD 5 y 72% 100% 78% Åstrand P et al 2004 FB 5 y 95% - Örtorp A et al 2004 FB 5 y 99.5% 100%* 89% 97%* 100% 100%* 95% 96.5%* FB, fixed bridge; OD, overdenture; * The reference includes 2 study groups.

3 Table 2. Overview of cumulative survival/success rates () in partial replacements. Partial replacements Prosthesis F-up Attard N et al 2003 FPD 8 y 92% 89% Glauser R et al 2007 FPD 5y 97% - - Gunne J et al 1999 FPD 10 y 88% % - Jemt T & Lekholm U 1993 FPD 5 y 97% 100% Jemt T et al 2003 (Group A) FPD 5 y 99% 100% 97.5% Lekholm U et al 1994 Lekholm U et al 1999 FPD FPD 5 y 10 y 92% 90% 86.5% Wyatt CCL & Zarb GA 1998 FPD 5 y 97% Zarb GA & Schmitt A 1993 FPD 5 y 92% 98% - - Zarb GA & Schmitt A 1993 FB/OD 5 y 89% 100% 100% FB, fixed bridge; OD, overdenture; FPD, fixed partial denture Table 3. Overview of cumulative survival/success rates () in single tooth replacements. Single tooth replacements F-up Andersson B et al y NR 98.5% NR 94 % Andersson B et al y - 100% - 97% Henry PJ et al y NR 97% - - Polizzi G et al y 93% - Scheller H et al y NR 98% NR 91 % NR, not reported in the table (< 20 implants)

4 References 1. Andersson B, Ödman P, Lindvall A-M, Brånemark P-I. Cemented single crowns on osseointegrated implants after 5 years: Results from a prospective study on CeraOne. Int J Prosthodont 1998;11: Andersson B, Ödman P, Lindvall A-M, Brånemark P-I. Five-year prospective study of prosthodontic and surgical single-tooth implant treatment in general practices and at a specialist clinic. Int J Prosthodont 1998;11: Attard NJ, Zarb GA. Implant prosthodontic management of partially edentulous patients missing posterior teeth: The Toronto experience. J Prosthet Dent 2003;89: Attard NJ, Zarb GA. Long-term treatment outcomes in edentulous patients with implant-fixed prostheses: The Toronto study. Int J Prosthodont 2004;17: Attard NJ, Zarb GA. Long-term treatment outcomes in edentulous patients with implant overdentures: The Toronto study. Int J Prosthodont 2004;17: Berglundh T, Persson L, Klinge B. A systematic review of the incidence of biological and technical complications in implant therapy reported in prospective longitudinal studies of 5 years. J Clin Periodontol 2002;29 (suppl 3): Bergendal T, Engquist B. Implant-supported overdentures: A longitudinal prospective study. Int J Oral Maxillofac Implants 1998;13: Carlsson GE, Lindquist LW, Jemt T. Long-term marginal periimplant bone loss in edentulous patients. Int J Prosthodont 2000;13: (See also reference Ekelund JA et al 2003) 9. Ekelund JA, Lindquist L, Carlsson G, Jemt T. Implant treatment in the edentulous mandible: A prospective study on Brånemark system implants over more than 20 years. Int J Prosthodont 2003;16: Eliasson A, Palmqvist S, Svenson B, Sondell K. Five-year results with fixed complete-arch mandibular prostheses supported by 4 implants. Int J Oral Maxillofac Implants 2000;15: Ericsson I, Randow K, Nilner K, Peterson A. Early functional loading of Brånemark dental implants: 5-year clinical follow-up study. Clin Implant Dent Relat Res 2000;2: Friberg B, Nilson H, Olsson M, Palmquist C. MkII: the self-tapping Brånemark implant. 5-year results of a prospective 3-center study. Clin Oral Impl Res 1997;8: Glauser R, Zembic A, Ruhstaller P, Windisch S. Five-year results of implants with an oxidized surface placed predominantly in soft quality bone and subjected to immediate occlusal loading. J Prosthet Dent 2007;97(suppl): S59-S Gunne J, Åstrand P, Lindh T, Borg K, Olsson M. Tooth-implant and implant supported fixed partial dentures: a 10- year report. Int J Prosthodont 1999;12: Hemmings KW, Schmitt A, Zarb GA. Complications and maintenance requirements for fixed prostheses and overdentures in the edentulous mandible: A 5-year report. Int J Oral Maxillofac Implants 1994;9: (See also reference Attard NJ & Zarb GA 2004) 16. Henry PJ, Laney WR, Jemt T, Harris D, Krogh PHJ, Polizzi G, Zarb GA, Herrmann I. Osseointegrated implants for single-tooth replacement: A prospective 5-year multicenter study. Int J Oral Maxillofac Implants 1996;11: Jemt T. Fixed implant-supported prostheses in the edentulous maxilla. A five-year follow-up report. Clin Oral Impl Res 1994;5: Jemt T, Chai J, Harnett J, Heath M R, Hutton J E, Johns R B, McKenna S, McNamara D C, van Steenberghe D, Taylor R, Watson R M, Herrmann I. A 5-year prospective multi-center follow-up report on overdentures supported by osseointegrated implants. Int J Oral Maxillofac Implants 1996;11:291-8.(See also reference Watson RM et al 1997) 19. Jemt T, Bergendal B, Arvidson K, Bergendal T, Karlsson U, Lindén B, Rundcrantz T, Wendelhag I. Implantsupported welded titanium frameworks in the edentulous maxilla: A 5-year prospective multicenter study. Int J Prosthodont 2002;15: Jemt T, Lekholm U. Oral implant treatment in posterior partially edentulous jaws: A 5-year follow-up report. Int J Oral Maxillofac Implants 1993;8: Jemt T, Henry P, Lindén B, Naert I, Weber H, Wendelhag I. Implant-supported laser-welded titanium and conventional cast frameworks in the partially edentulous jaw: A 5-year prospective multicenter study. Int J Prosthodont 2003;16:

5 22. Lekholm U, van Steenberghe D, Herrmann I, Bolender C, Folmer T, Gunne J, Henry P, Higuchi K, Laney WR, Lindén U. Osseointegrated implants in the treatment of partially edentulous jaws: A prospective 5-year multicenter study. Int J Oral Maxillofac Implants 1994;9: Lekholm U, Gunne J, Henry P, Higuchi K, Lindén U, Bergström C, van Steenberghe D. Survival of the Brånemark Implant in partially edentulous jaws: A 10-year prospective multicenter study. Int J Oral Maxillofac Implants 1999;14: Lindquist LW, Carlsson GE, Jemt T. A prospective 15-year follow-up study of mandibular fixed prostheses supported by osseointegrated implants. Clinical results and marginal bone loss. Clin Oral Impl Res 1996;7: (See also reference Ekelund JA et al 2003) 25. Naert I, Gizani S, Vuylsteke M, van Steenberghe D. A 5-year randomized clinical trial on the influence of splinted and unsplinted oral implants in the mandibular overdenture therapy. Part I: Peri-implant outcome. Clin Oral Impl Res 1998;9: Naert I, Alsaadi G, van Steenberghe D, Quirynen M. A 10-year randomized clinical trial on the influence of splinted and unsplinted oral implants retaining mandibular overdentures: peri-implant outcome. Int J Oral Maxillofac Implants 2004;19: Olsson M, Gunne J, Åstrand P, Borg K. Bridges supported by free-standing implants versus bridges supported by tooth and implant. A five-year prospective study. Clin Oral Impl Res 1995;6: (See also reference Gunne J et al 1999) 28. Polizzi G, Fabbro S, Furri M, Herrmann I, Squarzoni S. Clinical application of narrow Brånemark System implants for single-tooth restorations. Int J Oral Maxillofac Implants 1999;14: Scheller H, Pi Urgell J, Kultje C, Klineberg I, Goldberg PV, Stevenson-Moore P, Alonso JMN, Schaller M, Corria RM, Engquist B, Toreskog S, Kastenbaum F, and Smith CR. A 5-year multicenter study on implant-supported single crown restorations. Int J Oral Maxillofac Implants 1998;13: Watson RM, Jemt T, Chai J, Harnett J, Heath MR, Hutton JE, Johns RB, Lithner B, McKenna S, McNamara DC, Naert I, Taylor R. Prosthodontic treatment, patient response, and the need for maintenance of complete implantsupported overdentures: An appraisal of 5 years of prospective study. Int J Prosthodont 1997;10: Wyatt CCL, Zarb GA. Treatment outcomes of patients with implant-supported fixed partial prostheses. Int J Oral Maxillofac Implants 1998;13: Zarb GA, Schmitt A. The longitudinal clinical effectiveness of osseointegrated dental implants: The Toronto study. Part I: Surgical results. J Prosthet Dent 1990;63:451-7; Part II: The prosthetic results. J Prosthet Dent 1990;64:53-61; Part III: Problems and complications encountered. J Prosthet Dent 1990;64: (See also reference Attard Nj & Zarb GA 2004) 33. Zarb GA, Schmitt A. Osseointegration and the edentulous predicament. The 10-year-old Toronto study. Br Dent J 1991;170: (See also reference Attard NJ & Zarb GA 2004) 34. Zarb GA, Schmitt A. The longitudinal clinical effectiveness of osseointegrated dental implants in anterior partially edentulous patients. Int J Prosthodont 1993;6: Zarb GA, Schmitt A. The longitudinal clinical effectiveness of osseointegrated dental implants in posterior partially edentulous patients. Int J Proshtodont 1993;6: Åstrand P, Engquist B, Dahlgren S, Gröndahl K, Engquist E, Feldmann H. Astra Tech and Brånemark system implants: a 5-year prospective study of marginal bone reactions. Clin Oral Impl Res 2004;15: Örtorp A, Jemt T. Clinical experiences of computer numeric control-milled titanium frameworks supported by implants in the edentulous jaw: A 5-year prospective study. Clin Implant Dent Relat Res 2004;6:

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