Controversies and Advances in the Treatment of Cardiovascular Disease The Sixteenth in the Series. November 17 & 18, 2016 Montage Beverly Hills

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1 Controversies and Advances in the Treatment of Cardiovascular Disease The Sixteenth in the Series November 17 & 18, 2016 Montage Beverly Hills Wednesday, November 16, :00 8:00 PM Welcome Reception & Registration Montage Beverly Hills, Marquesa Foyer Oral Abstract Presentation Session Chair: Wen Cheng, MD Thursday, November 17, :00 7:45 AM Registration, Continental Breakfast, and Visit Exhibits 7:45 7:50 AM Welcome Address Program Directors: Raj Makkar, MD, FACC, John G. Harold, MD, MACC 7:50 8:00 AM ACC Welcome Address Garwood Gee, MD, FACC Session I: Atherosclerosis and Dyslipidemia Chair: P.K. Shah, MD, MACC 8:00 8:30 AM Novel Pathways to Inflammation in Atherosclerosis: From Gut Microflora to Don t Eat Me Signals P.K. Shah, MD, MACC 8:30 8:50 AM LDL-C Lowering: New Pathways Alan Brown, MD, FACC 8:50 9:10 AM Rethinking Dietary Fat Dariush Mozaffarian, MD, DrPH

2 9:10 9:30 AM Elevated Triglycerides: Legitimate Target or Not? Henry Ginsberg, MD 9:30 10:00 AM Roundtable Discussion 10:00 10:30 AM Break & Visit Exhibits Session II: Hypertension Chair: Ronald G. Victor, MD, FACC 10:30 10:45 AM New BP Goals to SPRINT or Not to SPRINT? Franz H. Messerli, MD, FACC 10:45 11:00 AM Are There Any Indications for Renal Artery Stenting After ASTRAL and CORAL? Jeffrey W. Olin, DO, FACC 11:00 11:15 AM Benefits of Heart Rate Lowering BEAUTIFUL, SIGNIFY, and SHIFT Reanalyzed Franz H. Messerli, MD, FACC 11:15 11:30 AM Fibromuscular Dysplasia: The Rare Disease That Isn t Jeffrey W. Olin, DO, FACC 11:30 11:45 AM Can Barbers Cut Blood Pressure Too? The LA Barbershop Blood Pressure Study Ronald G. Victor, MD, FACC 11:45 12:00 PM Renal Denervation Where Do We Go From Here? Florian Rader, MD, MSc, FACC 12:00 12:10 PM Roundtable Discussion 12:10 1:10 PM Lunch Thrombolytic Therapy / Catheter-directed Therapy for Acute Submassive PE 1:10 1:20 PM For Victor Tapson, MD 1:20 1:30 PM Against Timothy A. Morris, MD 1:30 1:40 PM Roundtable Discussion Suhail V. Dohad, MD, FACC, Timothy A. Morris, MD, Victor Tapson, MD

3 Session III: Update on MACRA: Medicare Access and CHIP Reauthorization Act of 2015 Chair: John G. Harold, MD, MACC 1:40 2:00 PM The Doc Fix Bill A Deep Dive into How MACRA (Medicare Reform Law and CHIP Reauthorization Act of 2015) Will Affect Your Practice C. Michael Valentine, MD, FACC 2:00 2:20 PM New Payment Models: What Does This Mean for Cardiology? Paul N. Casale, MD, MPH, FACC 2:20 2:40 PM Medicare Access and CHIP Reformation Act of 2015: Examining Physician Efforts to Prepare for Medicare Payment Reforms Richard F. Wright, MD, FACC 2:40 3:00 PM Piecing Together the MACRA Puzzle: How the ACC and NCDR Will Help Members Navigate Radical Changes Ahead Ralph G. Brindis, MD, MPH, MACC 3:00 3:10 PM Roundtable Discussion 3:10 3:20 PM Quantifying the Promise of a Connected Future Raj Khandwalla, MD, FACC 3:20 3:50 PM Keynote Lecture: Duchenne Muscular Dystrophy and the HOPE Trial Eduardo Marbán, MD, PhD, FACC 3:50 4:10 PM Break & Visit Exhibits Session V: Controversies in Advanced Heart Disease Chairs: Jon A. Kobashigawa, MD, FACC, Alfredo Trento, MD, FACC 4:10 4:30 PM Innovations in the Treatment of Pulmonary Hypertension Victor Tapson, MD Pulmonary Hypertension in Left Heart Disease: Is There an Indication to use Pulmonary Arterial Hypertension (PAH) Specific Therapy? 4:30 4:40 PM Pro: PAH Specific Therapy is Beneficial Antoine Hage, MD, FACC 4:40 4:50 PM Con: PAH Specific Therapy is Deleterious Michael I. Lewis, MD 4:50 5:00 PM Roundtable Discussion

4 The New UNOS Donor Heart Allocation Proposal is Fair? 5:00 5:10 PM Pro Evan Kransdorf, MD, PhD 5:10 5:20 PM Con Joshua S. Chung, MD 5:20 5:30 PM Roundtable Discussion 5:30 PM Adjourn

5 Controversies and Advances in the Treatment of Cardiovascular Disease The Sixteenth in the Series November 17 & 18, 2016 Montage Beverly Hills Friday, November 18, :00 7:25 AM Registration, Continental Breakfast, and Visit Exhibits 7:25 7:30 AM Welcome Address Program Directors: Raj Makkar, MD, FACC, John G. Harold, MD, MACC Session VI: Clinical Electrophysiology Chairs: Sumeet S. Chugh, MD, FACC, David S. Cannom, MD, FACC, Jeffrey S. Goodman, MD, FACC, and William J. Mandel, MD, FACC Silent Atrial Fibrillation 7:30 7:40 AM Quiet Yet Serious, Manage Immediately Sumeet S. Chugh, MD, FACC 7:40 7:50 AM No Treatment Without Symptoms Win-Kuang Shen, MD, FACC 7:50 8:00 AM Roundtable Discussion Risk of Sudden Death in Hypertrophic Cardiomyopathy 8:00 8:10 AM All You Need is Cardiac MRI Raymond K. Kwong, MD, MPH 8:10 8:20 AM Only the Clinical Profile Determines Risk Barry J. Maron, MD, FACC 8:20 8:30 AM Roundtable Discussion

6 Catheter Ablation of Ischemic Ventricular Tachycardia 8:30 8:40 AM Reach for the Catheter with the First ICD Shock Ashkan Ehdaie, MD 8:40 8:50 AM Where s the Fire, What About Drugs? Eugenio Cingolani, MD 8:50 9:00 AM Roundtable Discussion Time for the Subcutaneous Device to Replace the Transvenous Defibrillator? 9:00 9:10 AM Protagonist Charles Swerdlow, MD, FACC 9:10 9:20 AM Antagonist Michael Shehata, MD, FACC 9:20 9:30 AM Roundtable Discussion 9:30 10:00 AM Break & Visit Exhibits 10:00 10:30 AM Keynote Lecture: A Contemporary Perspective on Global Health Salim Yusuf, MD, DPhil, OC 10:30 11:00 AM Keynote Lecture: The Big Picture in Interventional Cardiology Martin B. Leon, MD, FACC Session VII: Unresolved Issues and Remaining Challenges in Antithrombotic Therapies and PCI Chair: Sanjay Kaul, MD, MPH, FACC Case Presentations to Illustrate Gaps in Evidence 11:00 11:15 AM What Role does Cangrelor Have? Sanjay Kaul, MD, MPH, FACC 11:15 11:30 AM Choice of Anticoagulants at the Time of PCI Timothy D. Henry MD, FACC 11:30 11:45 AM Bioresorbable Scaffolds: Where Are We Now? Morton J. Kern, MD, FACC 11:45 AM 12:00 PM PCI vs. CABG for LM CAD: Has Equipoise Been Disturbed by the Results of EXCEL and NOBLE Trials? Sanjay Kaul, MD, MPH, FACC

7 12:00 1:00 PM Lunch (Lunch activities are not included in CME hours.) Panel: A SWOT Analysis of Cardiovascular Healthcare in the Setting of the Repeal of Obama Care and the Inception of Trump Care Moderator: Gregory P. Fontana, MD, FACC Discussants: John G. Harold, MD, MACC, Martin B. Leon, MD, FACC, Eduardo Marbán, MD, PhD, FACC, Michael J. Reardon, MD, FACC, Rhonda Robb, Larry Wood 1:00 1:15 PM Keynote Lecture: Current Controversies in the Treatment of Aortic Stenosis Martin B. Leon, MD, FACC Session VIII: Update in Cardiac Imaging Chair: Daniel Berman, MD, FACC 1:15 1:30 PM Ultrasound is the New Physical Exam Is This the Death of the Stethoscope? Robert J. Siegel, MD, FACC 1:30 1:45 PM Imaging of Coronary Atherosclerosis Marc Dweck, MD, PhD, FACC 1:45 2:00 PM 4D CT in Bioprosthetic Valves: Should Anticoagulation be Routine? Raj Makkar, MD, FACC 2:00 2:15 PM Break Initial Assessment of the Patient with Typical Angina 2:15 2:25 PM Coronary CTA Matthew Jay Budoff, MD, FACC 2:25 2:35 PM Stress Testing/Imaging Rory Hachamovitch, MD, MSc, FACC Recent Onset of Heart Failure: Most Patients with Heart Failure of Uncertain Etiology Should Have Cardiac MRI 2:35 2:45 PM Pro Subha V. Raman, MD, FACC 2:45 2:55 PM Con Takahiro Shiota, MD, FACC

8 2:55 3:10 PM Clinical Role of FFRct Daniel Berman, MD, FACC 3:10 3:30 PM Roundtable Discussion: Multimodality Cardiac Imaging: Relative Roles of CT, MRI, Echo, Nuclear Moderator: Discussants: Daniel Berman, MD, FACC Matthew Jay Budoff, MD, FACC, Rory Hachamovitch, MD, MSc, FACC, Subha V. Raman, MD, FACC, Robert J. Siegel, MD, FACC, B.K. Tamarappoo, MD, PhD 3:30 4:00 PM Keynote Lecture: A Historical Journey on the Treatment of Myocardial Infarction William W. O Neill, MD, FACC Session IX: STEMI Controversies Chairs: Timothy D. Henry, MD, FACC, David A. Cox, MD, FACC 4:00 4:15 PM Challenging STEMI Cases Multivessel Disease 4:15 4:25 PM Fix the Culprit and Go Back to Bed David A. Cox, MD, FACC 4:25 4:35 PM Complete Revascularization Instead Timothy D. Henry, MD, FACC 4:35 4:50 PM The Next Frontier: Advanced Cardiogenic Shock William W. O Neill, MD, FACC 4:50 5:00 PM Panel Discussion David A. Cox, MD, FACC, William J. French, MD, FACC, Timothy D. Henry, MD, FACC, William W. O Neill, MD, FACC, Ivan C. Rokos, MD, FACC

9 Session X: Interventional Cardiology: Structural Heart Disease /Coronary Artery Disease Chairs: Saibal Kar, MD, FACC, Michael J. Reardon, MD, FACC, Richard F. Wright, MD TRANSCATHETER THERAPY 5:00 5:15 PM Keynote Lecture: Barriers and Opportunities to the Treatment of Low Risk Patients with TAVR Michael J. Reardon, MD, FACC 5:15 5:30 PM Functional Mitral Regurgitation Can Be Successfully Treated with A Mitral Procedure Alone vs. Successful FMR Therapy will Require a Mitral and Ventricular Solution Debators: Discussants: Gregory P. Fontana, MD, FACC, Saibal Kar, MD, FACC, Martin B. Leon, MD, FACC, Raj Makkar, MD, FACC, Michael J. Reardon, MD, FACC CARDIOEMBOLIC STROKE Appendage Closure 5:30 5:40 PM Medical Therapy is All You Need for Stroke Prevention There is Not Enough Data to Support Appendage Closure Saibal Kar, MD, FACC 5:40 5:50 PM Closure of Appendage Should be Offered to All Patients with CHADS Vasc of >2 Richard F. Wright, MD, FACC 5:50 6:00 PM Roundtable Discussion Gregory P. Fontana, MD, FACC, Saibal Kar, MD, FACC, Raj Makkar, MD, FACC, Michael J. Reardon, MD, FACC, Alfredo Trento, MD, FACC, Richard F. Wright, MD, FACC 6:00 PM Final Adjournment