Cont roversies & Advances

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1 Cont roversies & Advances IN THE TREATMENT OF CARDIOVASCULAR DISEASE The Eighteenth in the Series November 15-16, 2018 Montage Beverly Hills Beverly Hills, California PROGRAM DIRECTORS: Raj Makkar, MD, FACC, P.K. Shah, MD, MACC, Alfredo Trento, MD, FACC, Saibal Kar, MD, FACC, John G. Harold, MD, MACC, Jon Kobashigawa, MD, FACC, Gregory P. Fontana, MD, FACC, Rahul Sharma, MD, and Ramin Manshadi, MD, FACC CO-SPONSORED BY Promedica International CME in cooperation with the California Chapter of the American College of Cardiology, the Arizona Chapter of the American College of Cardiology, the California Chapter of the Society of Thoracic Surgeons, and the International Academy of Cardiology

2 Controversies & Advances IN THE TREATMENT OF CARDIOVASCULAR DISEASE PROGRAM DESCRIPTION We look forward to the eighteenth annual Controversies and Advances in the Treatment of Cardiovascular Disease symposium! The two-day scientific program will offer realistic views on many controversial issues in cardiovascular disease today. Session topics will include atherosclerosis and dyslipidemia, cardiac imaging, advanced heart failure, coronary artery disease, structural heart disease, clinical electrophysiology, sex differences in cardiovascular aging, aortic dissection and pulmonary embolism management, and heart health and extreme endurance sports. Sessions will include a combination of lectures, debates, and roundtable discussions. A faculty of internationally known leaders has been invited to share their knowledge and experiences with complex and controversial cases. TARGET AUDIENCE This symposium is designed for cardiologists, interventional cardiologists, cardiovascular and thoracic surgeons, perfusionists, nurses, technicians and those involved in the diagnosis, treatment and care of individuals with controversial and complex cases of cardiac disease. LEARNING OBJECTIVES Upon completion of this course, participants should be able to: : : Analyze the latest advancements and emerging treatments for atherosclerosis and dyslipidemia : : Examine updates in cardiac imaging and discuss the roles and limitations for various imaging modalities : : Discuss the potential for personalized medicine in heart failure : : Evaluate the latest trials and innovations in interventional cardiology and coronary artery disease : : Debate the current controversies in structural heart disease : : Evaluate the latest updates in clinical electrophysiology FACULTY DISCLOSURE : : Compare sex differences in cardiovascular aging, cognitive decline, and the effect on health policy : : Explain the latest data in the treatment of aortic disease and pulmonary embolism management : : Discuss the pros and cons of renal denervation for the management of resistant hypertension : : Evaluate the latest advances in the management of aortic dissection and pulmonary embolism : : Debate the potential risks and benefits of extreme endurance sports on heart health In accordance with the ACCME Standards for Commercial Support, program directors, planning committees, faculty and all others in control of the educational content of the CME activity must disclose all relevant financial relationships with any commercial interest that they or their spouse/partner may have had within the past 12 months. If an individual refuses to disclose relevant financial relationships, they will be disqualified from being a part of the planning and implementation of this CME activity. Employees of a commercial interest with business lines or products relating to the content of the CME activity will not participate in the planning or any accredited portion of the conference. Disclosure will be made to all participants at the conference location, prior to the educational activity commencement.

3 The Eighteenth in the Series November 15 16, 2018 CME ACCREDITATION AND DESIGNATION Physicians: Promedica International is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Promedica International designates this live activity for a maximum of 16 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. Nurses: Provider approved by the California Board of Registered Nursing, Provider #8495 for 16 Contact Hours. Perfusionists: Category 1 CEUs for perfusionists will be determined by the American Board of Cardiovascular Perfusion and updated online at Registered Cardiovascular Invasive Specialist: CCI does not approve CEUs directly, however CCI will accept CEUs that have already been approved by accredited sponsors of the Accreditation Council for Continuing Medical Education (ACCME). RCIS attendees will claim the physician certificate option when completing the online evaluation and can use that certificate to claim CEUs from CCI. ABIM MOC ACCREDITATION Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 16 Medical Knowledge MOC points and Patient Safety MOC credits in the American Board of Internal Medicine s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. COMMERCIAL SUPPORT This program is supported in part by educational grants and exhibits from industry, in accordance with the ACCME Standards for Commercial Support. At the time of printing, a complete list of commercial supporters was not available. Appropriate acknowledgement will be given to all supporters in meeting materials onsite. CULTURAL AND LINGUISTIC COMPETENCY This activity is in compliance with California Assembly Bill 1195 which requires that all CME activities comprising a patient care element include curriculum addressing the topic of cultural and linguistic competency. The intent of this bill is to ensure that health care professionals are able to meet the cultural and linguistic concerns of a diverse patient population through effective and appropriate professional development. Cultural and linguistic competency was incorporated into the planning of this activity.

4 Faculty Program Directors Raj Makkar, MD, FACC P.K. Shah, MD, MACC Timothy D. Henry, MD, FACC Alfredo Trento, MD, FACC Saibal Kar, MD, FACC John G. Harold, MD, MACC Jon Kobashigawa, MD, FACC Gregory P. Fontana, MD, FACC Rahul Sharma, MD Ramin Manshadi, MD, FACC Local Faculty Ali Azizzadeh, MD, FACC C. Noel Bairey Merz, MD, FACC Daniel Berman, MD, FACC Luis Bowen, MD Susan Cheng, MD, MPH, MMSc Sumeet Chugh, MD, FACC Suhail Dohad, MD, RVT, FACC James Forrester, MD, FACC Eli S. Gang, MD, FACC Jeffrey Goodman, MD, FACC Sanjay Kaul, MD, MPH, FACC Raj Khandwalla, MD, MA, FACC Asher Kimchi, MD, FACC Michelle M. Kittleson, MD, PhD, FACC Evan Kransdorf, MD, PhD Frank Litvack, MD, FACC Eduardo Marbán, MD, PhD, FACC Luke Oakley, MD, FACC Jignesh Patel, MD, PhD, FACC Florian Rader, MD, MSc, FACC Danny Ramzy, MD, PhD, FACC Bruce Samuels, MD, FACC Aamir Shah, MD Michael Shehata, MD, FACC Robert Siegel, MD, FACC Charles Swerdlow, MD, FACC Balaji Tamarappoo, MD, PhD Victor Tapson, MD Louise Thomson, MB, ChB Sam Torbati, MD Invited Faculty Vinayak Bapat, MBBS, MS, FRCS(Ed), FRCS(CTh) Columbia University Medical Center New York, NY Jeroen J. Bax, MD, PhD, FACC Leiden University Medical Center Leiden, The Netherlands Susan Bell, MBBS, MSCI, MACC Vanderbilt University Medical Center Nashville, TN William Boden, MD, FACC VA New England Healthcare System Boston, MA Robert Bonow, MD, MS, MACC Northwestern University Feinberg School of Medicine Chicago, IL Alan S. Brown, MD, FACC Advocate Heart Institute Park Ridge, IL Matthew Budoff, MD, FACC Harbor-UCLA Medical Center Torrance, CA Vito M. Campese, MD Keck School of Medicine of USC Los Angeles, CA Nakela L. Cook, MD, MPH, FACC National Heart, Lung, and Blood Institute Bethesda, MD Prakash Deedwania, MD, FACC UCSF School of Medicine, San Francisco Fresno, CA Michael Emery, MD, MS, FACC Indiana University Health Carmel, IN Ted Feldman, MD, FACC Evanston Hospital Evanston, IL Francisco Fernandez-Aviles, MD, PhD, FACC Hospital General Universitario Gregorio Marañón Madrid, Spain Paul Friedman, MD, FACC Mayo Clinic Rochester, MN Jeffrey Goldberger, MD, MBA, FACC University of Miami Miami, FL David R. Holmes, Jr., MD, MACC Mayo Clinic Rochester, MN Martin B. Leon, MD, FACC Columbia University Medical Center New York Presbyterian Hospital New York, NY Michael Mack, MD, FACC Baylor Scott & White Health Plano, TX Elizabeth McNally, MD, PhD Northwestern Chicago, IL Roxana Mehran, MD, FACC Icahn School of Medicine at Mount Sinai New York, NY Jagat Narula, MD, PhD, MACC Mount Sinai Saint Luke's Hospital New York, NY Matthew Price, MD, FACC Scripps Clinic La Jolla, CA John Rumsfeld, MD, PhD, FACC American College of Cardiology Denver, CO Samir Saba, MD, FACC University of Pittsburgh Medical Center Pittsburgh, PA Patrick W. Serruys, MD, PhD, FACC Imperial College London, United Kingdom Rotterdam, The Netherlands Gregg Stone, MD, FACC Columbia University Medical Center The Cardiovascular Research Foundation New York, NY Michael Valentine, MD, FACC American College of Cardiology Lynchburg General Hospital Lynchburg, VA Matthew T. Wheeler, MD, PhD Stanford University Stanford, CA Brian Whisenant, MD, FACC Intermountain Medical Center Salt Lake City, UT Clyde Yancy, MD, MSc, MACC Northwestern University Feinberg School of Medicine Chicago, IL

5 Scientific Program 2018 Thursday, November 15 7:00 7:30 AM Registration, Continental Breakfast, and Visit Exhibits 7:30 7:55 AM Welcome Address Raj Makkar, MD, FACC John G. Harold, MD, MACC Michael Valentine, MD, FACC John Rumsfeld, MD, PhD, FACC 7:55 8:00 AM CA ACC Welcome Address Ramin Manshadi, MD, FACC 8:00 8:20 AM The Ronald G. Victor, MD Memorial Lecture Yes I Can: How to Transform a Small Community Hospital Into the Nation s #1 Cardiology Program in Five Decades James Forrester, MD, FACC SESSION I: ATHEROSCLEROSIS AND DYSLIPIDEMIA Chair: PK Shah, MD, MACC 8:20 8:40 AM Update on PCSK9 Inhibition PK Shah, MD, MACC 8:40 9:00 AM Lipids Beyond LDL: Focus on Lpa and TG Rich Lipoprotiens Alan S. Brown, MD, FACC 9:00 9:20 AM Cardioprotection with Novel Antidiabetic Agents Prakash Deedwania, MD, FACC 9:20 9:40 AM De-Risking Primary Prevention: Role of Imaging Matthew Budoff, MD, FACC 9:40 10:00 AM Break & Visit Exhibits SESSION II: UPDATE IN CARDIAC IMAGING Daniel S. Berman, MD, FACC, Balaji Tamarappoo, MD, PhD 10:00 10:10 AM Combining CAC with SPECT Daniel S. Berman, MD, FACC 10:10 10:20 AM Device Infections and Complications: Role of Imaging Louise Thomson, MB, ChB 10:20 10:35 AM Does Myocardial Viability Predict Improvement with Revascularization Robert Bonow, MD, MS, FACC 10:35 10:45 AM Coronary CTA is the Best First Test for Stable Chest Pain Matthew Budoff, MD, FACC 10:45 11:00 AM Pathology of Peripheral Artery Disease: Clinical Implications Jagat Narula, MD, PhD, MACC 11:00 11:20 AM DSE for Low Flow Low Gradient AS Robert Siegel, MD, FACC 11:20 AM 12:00 PM Perspectives on the 10-Year PARTNER Experience: The Clinical Evidence Establishing TAVR as a Meaningful Therapy Martin B. Leon, MD, FACC 12:00 1:00 PM Lunch (Lunch activities are not included in CME hours.) Moderators: Gregory P. Fontana, MD, FACC Frank Litvack, MD, FACC SESSION III: CONTROVERSIES IN ADVANCED HEART FAILURE Jon Kobashigawa, MD, FACC Jignesh Patel, MD, PhD, FACC 1:00 1:20 PM Personalized Medicine in Heart Failure Clyde Yancy, MD, MSc, MACC 1:20 1:40 PM New Technologies to Monitor Heart Failure Patients Raj Khandwalla, MD, MA, FACC 1:40 2:00 PM Personalized Medicine in Heart Failure: Are We There Yet? Ever? :: Pro: Evan Kransdorf, MD, PhD :: Con: Michelle M. Kittleson, MD, PhD, FACC

6 2:00 2:10 PM Discussion 2:10 2:30 PM We Have the Data; the Guidelines Are Done But How Much Do We Really Know About Heart Failure? Clyde Yancy, MD, MSc, MACC 2:30 2:45 PM Comprehensive Imaging in Heart Failure Jeroen J. Bax, MD, PhD, FACC 2:45 3:00 PM Break & Visit Exhibits SESSION IV: CORONARY ARTERY DISEASE Timothy D. Henry, MD, FACC Sanjay Kaul, MD, MPH, FACC 3:00 3:20 PM Innovations in Interventional Cardiology Roxana Mehran, MD, FACC 3:20 3:25 PM Case Presentation Luke Oakley, MD, FACC 3:25 3:35 PM Controversies in Cardiogenic Shock Timothy D. Henry, MD, FACC Danny Ramzy, MD, PhD, FACC 3:35 3:40 PM Case Presentation Luis Bowen, MD 3:40 4:00 PM Does ISCHEMIA Matter? Chair: Sanjay Kaul, MD, MPH, FACC :: For: Gregg Stone, MD, FACC :: Against: William Boden, MD, FACC 4:00 4:10 PM Discussion 4:10 4:50 PM Panel Five Burning Questions in Coronary Artery Disease 1. What Is the Optimal Strategy For Reassessing Lesion Severity? Anatomical vs. Physiological? 2. What Is the Current State of Evidence for PCI Left Main Disease? 3. What Is the Optimal Strategy for Revascularization in Multivessel CAD? 4. What Is the Ideal Regimen and Duration of DAPT Following PCI? 5. Where Are Bioresorbable Stents Today? Panelists: Vinayak Bapat, MBBS, MS, FRCS(Ed), FRCS(CTh) Ted Feldman, MD, FACC David R. Holmes, Jr., MD, FACC Martin B. Leon, MD, FACC Michael Mack, MD, FACC Roxana Mehran, MD, FACC Matthew Price, MD, FACC Bruce Samuels, MD, FACC Patrick W. Serruys, MD, PhD, FACC Gregg Stone, MD, FACC SESSION V: CONTROVERSIES IN STRUCTURAL HEART DISEASE Raj Makkar, MD, FACC, Saibal Kar, MD, FACC 4:50 5:10 PM Management of Severe AS Patient with Poor Access Surgical or Percutaneous? :: Surgical Vinayak Bapat, MBBS, MS, FRCS(Ed), FRCS(CTh) :: Percutaneous Ted Feldman, MD, FACC 5:10 5:40 PM LAA Closure Should This Be First Line Therapy? :: Pro Brian Whisenant, MD, FACC :: Con David R. Holmes, Jr., MD, MACC 5:40 6:00 PM Panel Discussion What Does COAPT Mean for the Treatment of FMR? Moderator: Saibal Kar, MD, FACC Discussants: David R. Holmes, Jr., MD, MACC Ted Feldman, MD, FACC Michael Mack, MD, FACC Brian Whisenant, MD, FACC

7 6:00 6:15 PM Imaging of the Mitral and Tricuspid Valve for Structural Intervention Jeroen J. Bax, MD, PhD, FACC 6:15 6:35 PM The Tricuspid Valve No Longer the Forgotten Valve Watchful Waiting or Early Intervention? :: Early Intervention Jeroen J. Bax, MD, PhD, FACC :: Watchful Waiting Michael Mack, MD, FACC 6:35 PM Special Guest Entertainment: Dana Carvey (This activity is not included in CME hours.) Friday, November 16 7:00 7:25 AM Registration, Continental Breakfast, and Visit Exhibits 7:25 7:30 AM Welcome Address Raj Makkar, MD, FACC John G. Harold, MD, MACC SESSION VI: CLINICAL ELECTROPHYSIOLOGY Sumeet Chugh, MD, FACC Eli S. Gang, MD, FACC Jeffrey Goodman, MD, FACC Michael Shehata, MD, FACC Charles Swerdlow, MD, FACC 7:30 7:54 AM Incorporating Genetic Testing into Cardiovascular Practice Elizabeth McNally, MD, PhD 7:54 8:18 AM Remote Monitoring Using a Smart Phone or Watch: From Implantable to Wearable Paul Friedman, MD, FACC 8:18 8:42 AM Present and Future of Catheter Ablation for Atrial Fibrillation Samir Saba, MD, FACC 8:42 9:06 AM Can We Personalize Risk Stratification for Sudden Death? Jeffrey Goldberger, MD, MBA, FACC 9:06 9:30 AM Break 9:30 10:00am Will CT Angiography Replace Invasive Angiogram for Routine CABG? Patrick W. Serruys, MD, PhD, FACC SESSION VII: SEX DIFFERENCES IN CARDIOVASCULAR AGING CARDIOVASCULAR DISEASE, COGNITION AND HEALTH POLICY Chair: Jeroen J. Bax, MD, PhD, FACC 10:00 10:10 AM Introduction and Overview - Can Inclusion of Women Improve Men s Health? C. Noel Bairey Merz, MD, FACC 10:10 10:30 AM Vascular Factors in Cognition: The Impact of Sex on Memory Susan Bell, MBBS, MSCI, MACC 10:30-10:50 AM Cardiovascular Aging, Sex Differences and Eicosonoids The Fountain of Youth? Susan Cheng, MD, MPH, MMSc 10:50 11:10 AM Bridging the Sex Gap in Early Myocardial Infarction Mortality Why It Matters Nakela L. Cook, MD, MPH, FACC 11:10 11:20 AM Discussion

8 November 15-16, 2018 SESSION VIII: AORTIC DISSECTION AND PULMONARY EMBOLISM MANAGEMENT Suhail Dohad, MD, RVT, FACC, Victor Tapson, MD 11:20 11:50 AM Aortic Dissection: :: Case Presentation :: Update :: Discussion Ali Azizzadeh, MD, FACC Panel: Suhail Dohad, MD, RVT, FACC Aamir Shah, MD Sam Torbati, MD 11:50 am 12:20 PM Pulmonary Embolism: :: Case Presentation :: Update :: Discussion Victor Tapson, MD, FACC Panel: Suhail Dohad, MD, RVT, FACC Aamir Shah, MD, FACC Sam Torbati, MD 12:20 12:50 PM Cell Therapy for Heart Disease What Have We Learned and Where Are We Headed? Eduardo Marbán, MD, PhD, FACC 12:50 1:20 PM Cardiovascular Regenerative Medicine: Lights, Shadows and Needs Francisco Fernandez-Aviles, MD, PhD, FACC 1:20 2:20 PM Lunch SESSION IX: HYPERTENSION Moderators: Florian Rader, MD, MSc, FACC Vito M. Campese, MD 2:20 2:50 PM Return of Renal Denervation :: Pro Florian Rader, MD, MSc, FACC :: Con Vito M. Campese, MD 2:50 3:00 PM Discussion Vito M. Campese, MD Florian Rader, MD, MSc, FACC 3:00 3:30 PM Break & Visit Exhibits SESSION X: HEART HEALTH AND EXTREME ENDURANCE SPORTS Chair: Ramin Manshadi, MD, FACC 3:30 4:10 PM Heart Health and Extreme Endurance Sports: Harmful or Beneficial? Matthew T. Wheeler, MD, PhD Michael S. Emery, MD, MS, FACC 4:10 4:30 PM Discussion Michael S. Emery, MD, MS, FACC Ramin Manshadi, MD, FACC Matthew T. Wheeler, MD, PhD California Chapter of the American College of Cardiology Annual Awards Celebration Dinner, Feed Your Soul featuring singer Michael Tomlinson 6:30 PM Reception 7:30 PM Doors Open Seating is limited. Register now! Registration: ACC member: $40 Member Guest: $75 Pre-register online at

9 Registration Information $595 Physician/Industry $395 Nurse/Resident/Technician $395 ACC National Member $195 California Chapter ACC Member/ Cardiac Care Associate $395 CASTS Member $195 CASTS Associate Member Registration fees include breakfasts and lunches, as well as scientific program materials. Please make checks payable to Promedica International CME in U.S. dollars drawn on a U.S. bank. Visa, MasterCard, Discover and American Express credit cards are also accepted. Registrations should be faxed, mailed or submitted online at To register, please complete the attached form and mail or fax to: Promedica International CME 300 Carlsbad Village Dr., Suite 108A-326 Carlsbad, CA Tel: (760) , Fax: (760) Rlaw@promedicacme.com Refunds All cancellations must be submitted in writing and refunds will be subject to a $100 administration charge. Cancellations cannot be accepted over the telephone. Refunds will not be available beginning 45 days prior to the symposium. Hotel Accommodations A special room rate of $415 per night plus taxes for single or double occupancy is available for program participants at the Montage Beverly Hills. Reserve your room prior to the cutoff date of October 22, 2018 by calling Mention your affiliation with the Controversies symposium to receive the special rate. Activity Evaluation Evaluation by online questionnaire will address content, presentation, and future educational needs. Controversies & Advances IN THE TREATMENT OF CARDIOVASCULAR DISEASE November 15 16, 2018 Montage Beverly Hills - Beverly Hills, California Visit us at for convenient online registration. Physician/Industry: $595 Nurse/Resident/ Technician: $395 ACC National Member: $395 California Chapter ACC Member/Cardiac Care Associate: $195 CASTS Member: $395 CASTS Associate Member: $195 All fees in US dollars drawn on US banks: P Check Enclosed P Visa/MasterCard P American Express P Discover Credit Card Number Expiration Date Signature First/Last Name P MD PRN PCCP PNP Institution Mailing Address City/State/Zip/Country Telephone Fax Address Specialty Please mail or fax to: Promedica International CME, 300 Carlsbad Village Dr., Suite 108A-326, Carlsbad, CA Tel: (760) , Fax: (760) , Rlaw@promedicacme.com

10 Promedica International CME 300 Carlsbad Village Dr., Suite 108A-326 Carlsbad, CA Cont roversies & Advances IN THE TREATMENT OF CARDIOVASCULAR DISEASE The Eighteenth in the Series November 15 16, 2018 Montage Beverly Hills Beverly Hills, California WHAT THEY RE SAYING: : : A unique and engaging symposium! The focus on controversy helps illuminate the material. : : Consistently great conference year after year! : : I was impressed by the evidence-based practice as a result of incredible research all around the world! : : This meeting has a broad coverage of cardiovascular topics with balanced discussion regarding diagnosis and treatment options and clinical outcomes. All speakers were excellent! : : Enjoyed the new information and the dynamic and cutting edge presentations. : : The program was outstanding and had practical applications for my daily practice. Presort Standard U.S. Postage PAID Permit 1948 San Diego CA