Integrated Management of Acute and Chronic Coronary Artery Disease

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1 20 th International Meeting Integrated Management of Acute and Chronic Coronary Artery Disease From Prevention to Intervention ORGANIZERS: KURT HUBER (Austria) HARALD DARIUS (Germany) BERNARD GERSH (USA) CHRIS GRANGER (USA) OTMAR PACHINGER (Austria) MAIN TOPICS: Acute Coronary Syndromes Acute Cardiovascular Care Antiplatelet Agents Anticoagulants Atrial Fibrillation Biomarkers Case Presentations Heart Failure Interventional Cardiology Master Lectures Prevention Structural Heart Disease Study Organisation Translational Medicine (Abstracts) Innsbruck, Austria Austria Trend Congress Hotel January 26-29, 2019 FINAL PROGRAM

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3 PREFACE This international meeting celebrates its 20 th anniversary. As in the past, the meeting is organized by the Association for the Promotion of Research in Arteriosclerosis, Thrombosis and Vascular Biology (ATVB), Vienna, Austria. It is patronized by the European Platelet Academy (EPA), and the Acute Cardiovascular Care Association (ACCA), a registered branch of the European Society of Cardiology (ESC). In 2019, more than 30 international and national experts will guarantee an interesting conference with important topics illustrating the most contemporary and topical clinical research data mainly in the field of acute coronary syndromes, acute cardiac care, atrial fibrillation, interventional cardiology, heart failure and prevention. A major focus will be on pharmacotherapy and devices as has been the case in prior meetings. Master lectures and interactive clinical case discussions will extend our knowledge and enhance the practical relevance of the program. The number of attendees is limited to a maximum of 100 persons in order to stimulate intense discussions with international experts on case presentations and main topics a rare situation in the current era of large meetings. The presenters of the best abstracts (a maximum of 18 abstracts will be accepted) will discuss their data with faculty members in moderated poster presentations. Two awards will be given for best-of-translational medicine and best-of-clinical medicine posters. The participants will be confined to the group of young cardiologists of tomorrow. In addition, presenters of posters will have free access to the whole meeting. We welcome your participation at this meeting. With best regards Kurt Huber (for the organizers) Patronage Sigmund Freud Privatuniversität Wien Österreichischer Herzfonds DEADLINE FOR ABSTRACT SUBMISSION January 10, 2019 (send your abstracts, A4 format, directly to kurt.huber@meduniwien.ac.at) 1

4 Saturday, January 26, 2019 Arrivals 19:30 Welcome Cocktail and Get-Together Evening Sunday, January 27, :50 Welcome K. Huber (AT) 09:00-11:00 Symposium 1: Controversies in Antithrombotic Strategies chairs: D. Gulba (DE), D. Kristensen (DK) 09:00-09:15 Case Presentation #1 H. Alber (AT) 09:15-09:40 GLOBAL LEADERS and COMPASS: How Do We Integrate These Data into Clinical Practice H. Darius (DE) 09:40-10:05 Neither an Apple Nor an Aspirin a Day Keeps the Doctor Away F.W.A. Verheugt (NL) 10:05-10:20 Case Presentation #2 C. Kaulfersch (AT) 10:20-10:40 A Plethora of Options, How To Make Sense of it All R. Welsh (CD) 10:40-11:00 Are Women Presenting with ACS Undertreated? R. Mehran (US) 11:00-11:30 Break, Exhibition 2

5 Sunday, January 27, :30-12:30 Symposium 2: Biovascular Scaffolds Resuscitated (partially sponsored by BIOTRONIK) chairs: I. Lang (AT), J. Wöhrle (DE) 11:30-12:00 Own Experience and Safety Profile of the Magnesium BVS J. Wöhrle (DE) 12:00-12:20 Promising Data from Second Generation Magnesium BVS H. Schühlen (DE) 12:20-12:30 Case Presentation #3 G. Friedrich (AT) 12:30-13:30 Lunch Break, Exhibition, Moderated Posters A (moderators: S. De Waha, DE, D. Gulba, DE, J. Wojta, AT) 13:30-14:30 Symposium 3: New Devices for the Interventional Cardiologist (sponsored by Boston Scientific) chairs: H. Schühlen (DE), K. Huber (AT) 13:30-13:50 Pulmonary Revscularization: A New Concept for Acute and Chronic Pulmonary Embolism I. Lang (AT) 13:50-14:10 TAVI in Asymptomatic Aortic Stenosis? H. Thiele (DE) 14:10-14:30 Are Protection Devices a Must in Structural Heart Disease? J. Wöhrle (DE) 3

6 Sunday, January 27, :30-15:30 Symposium 4: Interventional Cardiology chairs: O. Pachinger (AT), P. Clemmensen (DK) 14:30-14:50 CABG vs. PCI for Multivessel and LMCA Disease: Do We Have the Evidence? H. Thiele (DE) 14:50-15:05 Case Presentations #4 G. Christ (AT) 15:05-15:30 CTO: Challenges, Expectations and Outcomes R. Mehran (US) 15:30-16:00 Break, Exhibition 16:00-17:30 Symposium 5: Master Lectures I chairs: J. Deanfield (UK), M. Böhm (DE) 16:00-16:25 Highlights from ESC 2018 S. Blankenberg (DE) 16:25-16:50 Lessons from DSMBs When to Stop and Not to Stop a Trial S. Pocock (UK) 16:50-17:15 Lipid Lowering Strategies: An Updated Review of a Rapidly Changing Field H. Drexel (AT) 17:15-17:40 Renal Denervation Status Quo 2019 M. Böhm (DE) 17:40-18:00 Current Experience with Antidots for NOACs R. De Caterina (IT) 18:00-18:30 Allan Ross Memorial Lecture Twenty Years of STEMI Treatment S. Kristensen (DK) 20:00 Networking Evening 4

7 Monday, January 28, :00-11:00 Symposium 6: Structural Heart Disease chairs: I. Lang (AT), U. Zeymer (DE) 09:00-09:15 Case Presentation #5 J. Auer (AT) 09:15-09:40 Mitral and Tricuspidal Valve Interventions Update 2019 H. Thiele (DE) 09:40-10:05 TAVR in Low-to-Medium Risk Patients with Aortic Stenosis R. Welsh (CA) 10:05-10:20 Case Presentation #6 S. Harb (AT) 10:20-10:40 TAVI in Centers without Surgery The Austrian Experience K. Huber (AT) :00 Thrombus Detection, Consequences and Anticoagulation after TAVI C. Hengstenberg (AT) 11:00-11:30 Break, Exhibition 11:30-12:30 Symposium 7: Heart Failure (partially supported by Novartis) chairs: C. Müller (CH), V. Gasparovic (HR) 11:30-11:50 Innovative Approaches to the Future Management of Chronic Heart Failure M. Böhm (DE) 11:50-12:10 Peripartum Cardiomyopathy S. Price (UK) 12:10-12:30 HFpEF Update 2019 A. Lyon (UK) 12:30-13:30 Lunch Break, Exhibition, Moderated Posters B (moderators: P. Clemmensen, DK, S. De Waha, DE, D. Gulba, DE) 5

8 Monday, January 28, :30-14:30 Symposium 8: Protecting Heart and Brain to Save Patient Lives (sponsored by Boehringer-Ingelheim) chairs: H. Drexel (AT), C. Hengstenberg (AT) 13:30-13:50 The New ADA-EASD Consensus Cardiodiabetology Established? T. Wascher (AT) 13:50-14:10 Low Dose NOACs: Which Evidence Do We Have? H. Alber (AT) 14:10-14:30 North American and European Differences in the Treatment of Patients with AFib and ACS K. Huber (AT) 14:30-15:30 Symposium 9: ECG Pearls moderated and presented by M. Borggrefe (DE) and R. Hatala (SK) and discussed by the audience 15:30-16:00 Break, Exhibition 6

9 Monday, January 28, :00-17:30 Symposium 10: Master Lectures II chairs: O. Pachinger (AT), H. Darius (DE) 16:00-16:25 Highlights from AHA 2018 C. Granger (US) 16:25-16:50 The Five Pivotal Trials of 2018 S. Pocock (UK) 16:50-17:15 Indications for PCI in Stable Angina, Implications of ORBITA and FAME-2 B. Gersh (US) 17:15-17:40 Diagnosis and Treatment of Amyloidosis Update 2019 A. Lyon (UK) 17:40-18:00 Antithrombotic Therapy in Stroke of Unknown Source: Oh Jesus ESUS!? R. De Caterina (IT) 18:00-18:30 Special Invited Lecture Inflammation and Cardiovascular Disease: Pathophysiology and Therapeutic Approaches J. Deanfield (UK) 20:00 Faculty Evening 7

10 Tuesday, January 29, :00-11:00 Symposium 12: Acute Cardiovascular Care (patronized by ACCA) chairs: V. Gasparovic (HR), S. Price (UK) 09:00-09:15 Case Presentation #7 S. Farhan (US) 09:15-09:40 Impella or/and ECMO: Indications and Differences P. Clemmensen (DK) 09:40-10:05 Echocardiography in the ICU S. Price (UK) 10:05-10:20 Case Presentation #8 J. Heindl (AT) 10:20-10:40 Cardiogenic Shock Recent Evidence U. Zeymer (DE) 10:40-11:00 Cardiac Arrest Novel Community Interventions C. Granger (US) 11:05-11:30 Break, Exhibition 11:30-12:30 Symposium 13: Atrial Fibrillation Moderator: H. Darius (DE), F.W.A. Verheugt (NL) 11:30-11:50 Atrial Fibrillation and LV Dysfunction: Pathophysiology and Management B. Gersh (US) 11:50-12:10 Screening and Wearables in Atrial Fibrillation C. Granger (US) 12:10-12:30 NOACs in Frail Patients F.W.A. Verheugt (NL) 12:30-13:30 Lunch Break, Exhibition, Moderated Posters C (moderators: P. Clemmensen, DK, J. Wojta, AT, S. De Waha, DE) 8

11 Tuesday, January 29, :30-14:30 Symposium 14: Biomarkers in CV Disease (partially sponsored BRAHMS/Thermofisher and ROCHE Diagnostics) moderators: S. Blankenberg (DE), J. Wojta (AT) 13:30-13:50 Present and Future Biomarkers in Heart Failure C. Müller (CH) 13:50-14:10 Biomarkers for Diagnosis in Acute Coronary Syndromes M. Möckel (DE) 14:10-14:30 Perioperative Myocardial Injury after Noncardiac Surgery C. Puelacher (CH) 14:30-14:55 Special Lecture CV Consequences of Sleep Apnoe and Is There Anything that We Can Do about It? B. Gersh (US) 15:00-16:00 Symposium 16: PCI Pearls in The Treatment of Complications A Potpourri of Catastrophies chairs: R. Welsh (CD), O. Pachinger (AT) 15:00-15:20 Germany (Case Presentation #9 and #10) U. Zeymer (DE), H. Schühlen (DE) 15:20-15:40 Denmark (Case Presentation #11 and #12) S. Kristensen (DK), P. Clemmensen (DK) 15:40-16:00 North America (Case Presentation #13 and #14) R. Welsh (CD), R. Mehran (US) 16:00-16:15 Twenty Years of Integrated Management and Predecessors: A Historical Review K. Huber (AT) 16:15 Poster Awards & Farewell K. Huber (AT) 16:30 End of Meeting 9

12 GENERAL INFORMATION Meeting Organization Association for the Promotion of Research in Arteriosclerosis, Thrombosis and Vascular Biology (ATVB), Mariahilferstrasse 49, A-1060 Vienna, Austria Responsible for the Scientific Program Kurt Huber, MD, FESC, FACC, FAHA Director, 3rd Department of Medicine Cardiology & Intensive Care Medicine, Wilhelminenhospital Montleartstrasse 37, A-1160 Vienna, Austria Phone: (+43/1) , Fax: (+43/1) Congress Secretariat Congress and Study Concept GesmbH Widerhoferplatz 4/3/19, A-1090 Vienna, Austria Contact: Ms. Mag. Franziska Beckmann Phone/Fax: (+43/699) Medical Exhibition & Advertising Medizinische Ausstellungs und Werbegesellschaft Freyung 6, A-1014 Vienna, Austria Contact: Ms. Sonja Chmella Phone: (+43/1) , Fax: (+43/1) Venue Austria Trend Hotel, Innsbruck Rennweg 12 a, A-6020 Innsbruck Phone: (+43/512) , Fax: (+43/512) Congress Fee: 600. /300. (reduced fee for physicians in education) 2-day attendance: 400. / day attendance: 200. /100. This meeting is credited with 28 credit points for advanced training diploma (DFP) by the Austrian Medical Association (ID ,

13 GENERAL INFORMATION Information for Poster Presenters You will get notion of acceptance of your abstract latest until January 15, There will be free access to the whole meeting for poster presenters. Posters (150x90 cm height x width) should be mounted on the indicated day (Sunday, Monday, or Tuesday) latest at 9:00 AM and removed at the evening of the same day. Poster presentation (3 min) and discussion (3 min) will take part during the indicated poster moderation sessions. Poster size should not exceed). The best posters will be awarded on Tuesday, January 29, 2019 at the end of the meeting. 11

14 SPONSORS (as per printing date) AstraZeneca 12

15 International Faculty Hannes ALBER (Austria) Stefan BLANKENBERG (Germany) Michael BÖHM (Germany) Martin BORGGREFE (Germany) Peter CLEMMENSEN (Denmark) Harald DARIUS (Germany) John DEANFIELD (United Kingdom) Raffaele DE CATERINA (Italy) Suzanne DE WAHA (Germany) Heinz DREXEL (Austria) Vladimir GASPAROVIC (Croatia) Bernard GERSH (USA) Chris GRANGER (USA) Dietrich GULBA (Germany) Robert HATALA (Slovakia) Christian HENGSTENBERG (Austria) Kurt HUBER (Austria) Steen D. KRISTENSEN (Denmark) Irene LANG (Austria) Alex LYON (United Kingdom) Roxana MEHRAN (USA) Martin MÖCKEL (Germany) Christian MÜLLER (Switzerland) Otmar PACHINGER (Austria) Stuart POCOCK (United Kingdom) Susanna PRICE (United Kingdom) Christian PUELACHER (Switzerland) Helmut SCHÜHLEN (Germany) Holger THIELE (Germany) Freek W.A. VERHEUGT (Netherlands) Thomas WASCHER (Austria) Rob WELSH (Canada) Jochen WÖHRLE (Germany) Johann WOJTA (Austria) Uwe ZEYMER (Germany) Austrian Case Presenters Johann AUER (Braunau) Günter CHRIST (Wien) Serdar FARHAN (Wien, New York) Guy FRIEDRICH (Innsbruck) Stefan HARB (Graz) Jörg HEINDL (St. Pölten) Carl KAULFERSCH (Klagenfurt) Printed in Austria by: ROBIDRUCK A-1200 Vienna

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