Subclavian Artery Plug Embolization (SAPE study): a real experience about endovascular subclavian occlusion prior to thoracic vascular repair
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1 Subclavian Artery Plug Embolization (SAPE study): a real experience about endovascular subclavian occlusion prior to thoracic vascular repair Simone Salvati, Luca Bertoglio, Alessandra Fittipaldi, Andrea Melloni, Andrea Kahlberg, Germano Melissano, Roberto Chiesa Vascular Surgery, Vita-Salute - San Raffaele University Scientific Institute Ospedale San Raffaele, Milan Italy Chief: Prof. Roberto Chiesa
2 Disclosure Simone Salvati, MD I do not have any potential conflict of interest
3 Carotid to subclavian BP during TEVAR In case of coverage of the LSA artery, SVS recommends routine pre-operative LSA revascularization CSB VA Plug CSB bypass
4 Subclavian artery plug embolization In case of CSB, LSA origin occlusion to avoid Type IC endoleak CSB VA Plug CSB VA Plug
5 Amplatzer Vascular Plug (AVP) 3 different devices to occlude aortic side branches AVP I AVP II AVP IV Diameter Sheath required Delivery system lenght Landing zone Flow type 4-16 mm 4-6 Fr 100 cm Shortest Low-medium 3-22 mm 4-7 Fr 100 cm Medium/long Medium-high 4-8 mm 4Fr diagnostic catheter 125 cm Short Low-medium
6 Subclavian Artery Plug Embolization (SAPE) study ClinicalTrials.gov Identifier: NCT Population: 92 patients treated with CSB and Plug occlusion - 70 patients retrospective - 22 patients prospective Inclusion: Elective cases scheduled for TEVAR, FET or B/FEVAR Primary endpoint: Primary technical success rate Secondary endpoints: neurological events, access complications Status: enrolling
7 SAPE study: anatomical characteristics Artery anatomy is mandatory for the choice of AVP Subclavian artery anatomy Length (median) 4.3 cm ( ) Diameter (mm) > 12 mm 55% < 12 mm 45%
8 SAPE study: anatomical characteristics Use of AVP according to the anatomical characteristics 12 mm 1 14 mm 6 AVP I 33 (36%) 16 mm mm 4 14 mm 6 16 mm 21 AVP II 59 (64%) 18 mm mm mm 12
9 SAPE study: technical aspects Type of vascular access Percutaneous 67% Cut-down 33% Femoral 16% Radial 49% Brachial 31% Subclavian 3%
10 SAPE study: clinical results Post-operative events and follow-up Adverse events Stroke 2 (2,5%) Access reoperations (brachial percutaneous) Asymptomatic thrombosis (radial access) 2 (2,5%) 7 (8,7%) Post-op follow up (CT scan) CBS patency at 2-year 93% Technical Success 95% Type IA-IC endoleak 5%
11 Tips & tricks: real experience Short neck in large subclavian artery
12 Tips & tricks: real experience AVP II protruding in the aorta
13 Tips & tricks: stent-graft sealing interference AVP II protruding in the aorta AVP II protruding in the aorta Risk of Type I EL for Zone 2 PLZ
14 Tips & tricks: stent-graft sealing interference Zone 2 sealing interference AVP II Plug Type I EL Type I EL AVP lobe Zone 2 TEVAR AVP II lobe protruding in the aorta
15 Tips & tricks: stent-graft sealing no interference Zone 0-1 no sealing interferences AVP II Plug Zone 1 PLZ no interferences
16 Tips & tricks: real experience Dissected subclavian artery
17 Tips & tricks: double lumen embolization TL and FL embolization TL AVP II plug FL AVP II plug TL and FL plug occlusion
18 Tips & tricks: subclavian dissection TL and FL embolization
19 Conclusions TECHNIQUE Quick with a single shot approach No dedicated plugs for the subclavian anatomy RESULTS High technical success rates Few associated complications
20 Thank you for your attention
21 Subclavian Artery Plug Embolization (SAPE study): a real experience about endovascular subclavian occlusion prior to thoracic vascular repair Simone Salvati, Luca Bertoglio, Alessandra Fittipaldi, Andrea Melloni, Andrea Kahlberg, Germano Melissano, Roberto Chiesa Vascular Surgery, Vita-Salute - San Raffaele University Scientific Institute Ospedale San Raffaele, Milan Italy Chief: Prof. Roberto Chiesa
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