Index. Bovine artery heterograft 256 Brescia-Cimino arteriovenous fistula 28, 212,250,253

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1 Index Acid-base balance, disturbances in 165 Acute tubular necrosis (A TN) 37 Age factors, in selection of patients Aluminium ,130 as a toxin 127, 165 Amyloidosis 13 Anaemia, cobalt chloride in, following bilateral nephrectomy 152 effect of androgens on effect of bilateral nephrectomy on 150 iron therapy for, in haemodialysis patients ,149 pathogenesis of in renal failure Analgesic nephropathy 12 Androgens, effects of on anaemia in haemodialysis patients Aneurysms, in vascular access procedures 251 in vein grafts 256 Angiotensin II, plasma 106, 107, 108, 114, 115 Anti-lymphocyte globulin (ALG) 39 Anti-platelet drugs 258,262 Anxiety neurosis 197 Artificial Kidney Assistants (AKA) 80, 83. Avascular necrosis , 178, 219 Azathioprine 39,220 Benzodiazepines 124 Bethanidine 112 Bilateral nephrectomy 12, 105, 108, Ill, 114,115,116,117,150 cobalt chloride in anaemia following 152 Blood transfusion, effect of in transplantation 42, Bovine artery heterograft 256 Brescia-Cimino arteriovenous fistula 28, 212,250,253 Cadaveric donors, for renal transplantation 36-37,216 Cadmium 165 Calcification, metastatic 172, 173, 178 pathogenesis of ectopic , Calcium 175 plasma 176, 177 Cardiac failure, in vascular access Cardiac tamponade 266 Cardiovascular, and hypertension problems, in selection for haemodialysis Cell-mediated immunity (CMI) 41,43,44 Cimino-Brescia arteriovenous fistula 28, 212,250,253 Clonidine 112 Cobalt chloride, in anaemia following bilateral nephrectomy 152 Collins solution 38 Cordis Dow dialyser 238,239,240,241, 242,244,247 Cost-benefit analysis 67,68 Creatinine 19,219,268 clearance 239,240,242,244,274 plasma 219 Cyclophosphamide 39 Cytomegalovirus 47 'Dead' kidneys 37 Diabetes mellitus 90 Diabetes, renal failure in Dialysers Cordis Dow 238,239,240,241,242, 244,247 Gambro 38,238,239,240,241,242,244, 245 Graham hoop 3,4 Kiil 30,238,267 Meltec multipoint 247,273 merits of four types 243 Nephros (Organon) 238,239,240,241, 242,244 polyacrylonitrile 273 Travenol 238,239,240,241,242,244, 247 Dialysis (see Haemodialysis) Dialysis dementia 38,134,135,136 Diazoxide 12 Dietary freedom, in haemodialysis 31 Dihydrotachysterol (DHT or AT 10) 183, 184

2 278 Dinitrochlorobenzene (DNCB) 43 Disequilibrium syndrome 124 Donors, living, for renal transplantation 36 cadaveric 36-37,216 Dyspepsia, due to steroids 218 Ectopic calcification, pathogenesis of ,217 Edinburgh Medical Renal Unit 205,207, 211 Encephalopathy syndrome, in haemodialysis , 130 aetiology of histopathology of 126 therapy for 126 Epstein-Barr (EB) virus 219 Erythropoiesis 138,140,141,149,151 European Cooperative Scheme 38 European Dialysis and Transplant Association (EDT A) Registry 14,22,24,26,40,44,56,57,231, 237,245 Eurotransplant 39 Exchangeable sodium 106, 107, 108, 109 Family, child's responses in effects of haemodialysis on 191, parental responses in Fluoride 135, 165 Gambro dialyser 38,238,239,240,241, 242,244,245 Giovanetti diets 16 Glasgow Blood Pressure Clinic 113 Glasgow, children on haemodialysis in Glasgow Royal Hospital for Sick Children Renal Unit 192 Glomerulonephritis 11, 148, 215 Graft stenosis, in vascular access procedure Grafts, vein , 259 haemorrhage in 256 thrombosis in 255,258 Graham hoop dialyser 3, 4 Graham, Thomas 2, 3 Haematoma, subdural 124 Haemodialysis, cardiovascular and hypertension problems in selection for LIVING WITH RENAL FAILURE children in Glasgow on cumulative survival in 94 depression in , 197 in diabetes 98 dietary freedom in 31 effects of on family 191, effects of pathogenetic mechanisms encephalopathy syndrome in ,130 aetiology of histopathology of 126 therapy for 126 European statistics for 23, 26 guidelines for home 16-17,72,73,77,212,215, 273 costs of 55,58 and housing 75,76 long-term effects of on the family proportion of patients on 62 rehabilitation after training patients for 229 hospital, costs of 54,58,60,72,212, 273 limited-care 63, 72, 78-79, 88 modality of 95 patients, age factors in selection annual blood loss in 141 blood transfusion in effect of androgens on anaemia in hypertension in iron deficiency in iron therapy for anaemia in ,149 psychological and social problems in selection of systemic disease in selection for transplantation 38 physical adaptation to 268 psychological and social factors during 192 quality of treatment self-care 88, facilities (SCF) 91, 96 initial modality of morbidity and mortality in transfers 92 sex factors in 147 single needle 28, 29 therapies 267

3 INDEX Haemoglobin 274 before and after iron therapy 143, 144, 146,147,149 Haemolysis 138 Haemorrhage, in vein grafts 256 Hand swelling, in vascular access Hawaii, dialysis facilities in 89, 98 Heparinization 98, 124,274 Hepatitis B 14,47,80,229 Heterograft, bovine artery 256 HLA antigens 47 HLA matching 36,217 Home haemodialysis 16-17,72,73,77, 212,215,273 costs of 55, 58 and housing 75,76 long-term effects of on family proportion of patients on 62 training patients for 229 Hospital haemodialysis, costs of 54, 58, 60,72,212,273 Hydralazine 112 Hypercalcaemia 175, 178 Hyperparathyroidism 167 Hypertension 11 and cardiovascular problems in selection for haemodialysis management of mechanisms of in patients undergoing haemodialysis Hypertensive renal disease 148 Hypophosphataemia 127, 134 Imferon 144 Immunosuppression 39 IMPRA (International Medical Prosthetic Research Association) 258 Interstitial nephritis 11 Iron deficiency, in haemodialysis patients Iron therapy, for anaemia in haemodialysis patients ,149 Ischaemia, limb, in vascular access Kidneys, 'dead' 37 polycystic disease of 143, 144, 145, 148, 150 survival 41 Kiil dialyser 30,238,267 Limb ischaemia, in vascular access Limited-care haemodilllysis 63,72, 78-79,88 Living donors, for renal transplantation 36 London Hospital Renal Unit 78 Looser's zones 217 Mass transfer therapy, relationship with protein catabolism Meltec multipoint dialyser 247,273 Metastatic calcification 172, 173, 178 Methyldopa 112 Methylprednisolone 219 Micronesia, dialysis facilities in 89 Mineral metabolism, disturbed 166 Minoxidil 12, 112, 116 side-effects of 113 Morbidity and mortality, in self-care haemodialysis National Organ Matching Scheme (NOMS) 36,39,217 Necrosis acute tubular (ATN) 37 avascular ,178,219 Nephrectomy, bilateral 12, 105, 108, 111, 114, 11~ 116, 11~ 150 cobalt chloride in anaemia following 152 Nephritis, interstitial 11 Nephros (Organon) dialyser 238,239, 240,241,242,244 Neuropathy, analgesic 12 'Newcastle bone disease' 129, 135, 184 Nocturia 218 North-East Thames Regional Health Authority 81 Nursing Administrator 226 Osteitis fibrosa 161, 162, , 178 Osteodystrophy 126, 130, 138 Osteomalacia 126, 128, 130, 134, 135, 164, ,178 Osteopaenia 178 Osteoporosis 171,216 Osteosclerosis, ofthe spine 170, 171 Parathyroid hormone 163, 167 Parathyroidectomy 135, 172, 176, 177, 178

4 280 Patient, age factors in selection for haemodialysis anxiety in adults treated by dialysis and transplant 53 problems of emotional stresses of 202, 204 grief reaction of 202 sexual problems in 203 -staff relationships 228, 229 systemic disease in selection for haemodialysis training for home dialysis 229 wellbeing of 27 Pericarditis, uraemic 12 Phosphate metabolism Plasma, angiotensin II 106, 107, 108, 114, 115 calcium 176, 177 creatinine 219 renin 106, 107, 108, 109, 110, Ill, 115 sodium 107 Polyacrylonitrile dialyser 273 Polycystic kidney disease 143, 144, 145, 148, 150 Polytetrafluoroethylene (PTFE) 13 vascular prostheses (Gore-Tex) ,263 Prazosin 112 Prednisolone 220 Primary renal disease, type of Protein catabolism, relationship with mass transfer therapy Psychological and social factors, in selection of patients averting problems in during haemodialysis 192 Pyelonephritis 11, 148 Pyroxidine 157 Quinton (Scribner) shunt 4, 28, 250, ,262 Reddy system 29 Regional Limited-Care Dialysis Unit 81 Regular dialysis treatment (RDT) 10, 11 Rehabilitation, after home dialysis after transplantation 44 Rejection, treatment of 39 Renal disease, bone definition and prevention of LIVING WITH RENAL FAILURE features of pathogenesis of 163 hypertensive 148 types of primary Renal failure international companies in treatment of pathogenesis of anaemia in toxins in 165 Renal transplantation 88,216,217 cadaveric donors for 36-37,216 costs of 55 living donors for 36 merits of 72 routine for 37 Renin 112 plasma 106, 107, 108, 109, 110, 111, 115 Royal Free Hospital Renal Unit 78 Royal Hospital for Sick Children, Glasgow, Renal Unit 192 Saphenous vein 251,259 grafts complications of Saralasin 115, 119, 120 Scribner (Quinton) shunt 4, 28, 250, ,262 Self-care haemodialysis 88, facilities for (SCF) 91, 96 initial modality of morbidity and mortality in transfers 92 Serum ferritin levels 142 Sigmoidoscopy 219 Single needle dialysis 28, 29 Social, and psychological factors in selection of patients Social convenience for haemodialysis Sodium 116 exchangeable 106, 107, 108, 109 plasma 107 Sparks mandril Staff, medical 227 nursing patient relationships 228, 229 problems in haemodialysis/transplant units 225 technical Staphylococcus aureus 256 Steroid therapy, effects of 218

5 INDEX St. Leonard's/St. Bartholomew's Regional Renal Unit 74, 75, 78, 79 Subdural haematoma 124 Subperiosteal erosions 161 Systemic disease, in selection of patients for haemodialysis Thiazide diuretics 112 Thompson, Thomas 1 Thrombosis, in vascular access procedures in vein grafts 255,258 Tissue typing 38,39-41,217 Toxins aluminium as 127, 165 in renal failure 165 Transplantation effects of blood transfusion in 42, renal, cadaveric donors for 36-37,216 living donors for 36 rehabilitation after 44 Travenol dialyser 238,239,240,241, 242,244,247 Treatment, choice of costs of duration of 30 quality of timing of 17 Uraemia 139, 140,266 'end-stage' 124 Uraemic pericarditis 12 Urea clearance 239,242,244, Vascular access, aneurysms in 251 cardiac failure in 252 complications of procedures in graft stenosis and thrombosis in hand swelling in 252 infection during 251 limb ischaemia in 252 techniques of Vein grafts 251, ,259 haemorrhage in 256 thrombosis in 255, 258 Vitamin A 165, 174 VitaminD 177,178,185 metabolism 160, 165, 174, 175 Western Infirmary, Glasgow 114