Systemic lupus erythematosus (SLE): Pleuropulmonary Manifestations
|
|
- Sophie Reynolds
- 6 years ago
- Views:
Transcription
1 08/30/10 09/26/10 Systemic lupus erythematosus (SLE): Pleuropulmonary Manifestations Camila Downey S. Universidad de Chile, School of Medicine, Year VII Harvard University, School of Medicine Sept 17, 2010
2 Agenda Introduction Pleural involvement Pulmonary involvement Airway involvement Pulmonary vascular disease Infections Patient Presentation Summary References Acknowledgements
3 SLE: Epidemiology Systemic lupus erythematosus (SLE): Is a chronic autoimmune disease characterized by microvascular inflammation with the generation of autoantibodies that can affect almost any organ system. Approximately 250,000 Americans have systemic lupus. (National Arthritis Data Working Group). Its presentation and course are highly variable.
4 SLE: Pleuropulmonary involvement The majority of patients with SLE develop pleural or pulmonary disease in the course of their illness, diagnosed clinically and or by images techniques. Respiratory involvement is more common in men than in women. The pleura is the most common thoracic localization of SLE.
5 SLE: Pleuropulmonary manifestations Infections Pleuritis with or without effusion Upper and lower airways disease Acute lupus pneumonitis Alveolar hemorrhage Organizing pneumonia Chronic interstitial lung disease Lymphocytic interstitial pneumonia Nonspecific interstitial pneumonia Usual interstitial pneumonia Desquamative interstitial pneumonia Respiratory muscle weakness (Shrinking lung syndrome) Pulmonary hypertension Pulmonary embolism Mediastinal lymphadenophaty Crestani B. The respiratory system in connective tissue disrders. Allergy 2005; 60:
6 Pleural involvement Pleural involvement may be asymptomatic, although pleuritic pain is very common. Clinically apparent effusions have been reported in up to 50% of patients and pathological involvement in autopsy in up to 93% of patients. Typically associated with chest pain, dyspnea, cough and fever. Crestani B. The respiratory system in connective tissue disorders. Allergy 2005; 60:
7 Acute lupus pneumonitis Lung parenchyma involvement can be acute or chronic. Acute lupus pneumonitis: Non specific, may simulate infection, pulmonary embolism or other. Variable degree of respiratory impairment accompanied by focal or diffuse pulmonary consolidation. Crestani B. The respiratory system in connective tissue disorders. Allergy 2005; 60:
8 Acute pulmonary hemorrhage Acute pulmonary hemorrhage: Bilateral lung infiltrates, ranging from limited ground glass opacities to dense consolidation. Consolidation can be diffuse or patchy. Crestani B. The respiratory system in connective tissue disorders. Allergy 2005; 60:
9 Pulmonary fibrosis Chronic interstitial pulmonary disease: Pulmonary fibrosis: honeycomb changes with peripheral and basal predominance, linear thickened interlobular septae, ground glass attenuation and parenchymal bands. Eun A Kim et al. Interstitial lung diseases associated with collagen vascular diseases: Radiological and histopathologic findings. RadioGraphics 2002; 22:
10 Lymphocytic interstitial pneumonia Lymphocytic interstitial pneumonia (LIP): Usually associated with Sjogren syndrome. Ground glass opacity, poorly defined centrilobular nodules, thickening of bronchovascular bundle, interlobular septae and cystic airspaces. Patchy alveolar infiltrates. Lawrence Kenney et al. Lymphocytic interstitial pneumonitis in a woman with tangier s disease. Chest 2004; 126(4): 977S.
11 Uncommon in SLE. Camila Downey, 2010 Airway Involvement Upper airway, glottis and cricoarytenoid joints seem to be the most commonly involved sites.
12 Pulmonary vascular disease Pulmonary Hypertension: Present in 5 14% of patients. Prevalence tend to increase with time. Few cases result in right heart failure. Diagnosis suspected on echocardiography and confirmed by cardiac catheterization. Image from PACS, BIDMC
13 Pulmonary Hypertension Dilated main pulmonary artery, abnormalities in perfusion, heterogeneity of lung attenuation (mosaic perfusion). Images from PACS, BIDMC
14 Pulmonary embolism Pulmonary embolism: Mostly associated with Antiphospholipid syndrome. Chronic pulmonary embolism can lead to pulmonary hypertension. Tasneem A. Lalani et al. Imaging Findings in Systemic Lupus Erythematosus. RadioGraphics 2004; 24(4):
15 Pulmonary infections Infection is a major cause of morbidity and mortality in SLE. 50 % of deaths reported in some series. Secondary to inmunosuppression associated with SLE itself and induced by corticosteroids and immunosuppressants. Susceptible to usual pathogens and opportunistic pathogens. Mycobacterial and Nocardial infections seem particularly important
16 Mycobacterial and Nocardial Mycobacterial Infection: Consolidation and cavitation of left apex. infection Nocardial infection: Consolidation and cavitation of right upper lobe. Tasneem A. Lalani et al. Imaging Findings in Systemic Lupus Erythematosus. RadioGraphics 2004; 24(4):
17 Shrinking lung syndrome Dyspnea associated with small lung volumes, elevated hemidiaphragms and bibasilar atelectasis. Syndrome attributed to diaphragmatic dysfunction (myopathy) on the basis of demonstration of decreased respiratory muscle strength
18 Shrinking lung syndrome: Images Elevated hemidiaphragms, small lung volumes, and bibasilar atelectasis David A. Lynch MB. Lung disease related to collagen vascular disease. J Thorac Imaging 2009; 24(4):
19 Our patient: 32 years old female. Camila Downey, 2010 Our patient Past medical history: SLE course complicated by nephritis, anemia, serositis and ascites. Vascular stenosis resulting in facial edema and subclavian steal. Stage IV sacral decubitus ulcer complicated by osteomyelitis Gastroesophageal reflux disease
20 Clinical Case: Past medical history Past medical history ESRD status post failed renal transplant requiring explant, currently on hemodialysis three times a week. Multiple hospitalizations for line sepsis. History of MSSA endocarditis complicated by embolic stroke and resultant seizure disorder. Sickle cell trait Pulmonary hypertension Restrictive lung disease
21 Clinical Case: Actual history Consults because of history of worsening shortness of breath, worse when lying down in last few weeks. Patient denies any chest pain or cough. Findings on physical exam: Febrile up to 101 Heart rate: 83, Blood pressure: 110/75, Respiratory rate: 16, SpO2: 98% on 2 liters of O2 on admission Pulmonary exam: Crackles at bases bilaterally no increased work of breathing.
22 Clinical Case: Laboratory exams Findings on laboratory exams: Hematocrit: 23.2%, repeated: 21.8% Hemoglobin: 7.1 mg/dl. Patient was transfused one unit of packed red blood cells, with appropriate rise in hematocrit and improvement in shortness of breath.
23 Clinical Case: Images During work up, concerning for multifocal pneumonia vs. pulmonary congestion Chest X Ray (CXR) and Computed Tomography (CT) are obtained
24 Image from PACS, BIDMC Camila Downey, 2010 CXR and Coronal CT
25 Chest X Ray Findings concerning for multifocal pneumonia though a component of vascular congestion cannot be entirely excluded. Increased ground glass opacities. Atelectasis and pleural effusions.
26 Chest CT: Effusions, atelectasis Bilateral moderate sized pleural effusions worsen since three months ago. Adjacent atelectasis at lung bases Increased heterogeneous air space disease compatible with multifocal pneumonia.
27 Chest CT: Pulmonary edema Significant prominence of pulmonary vasculature with septal thickening and patchy ground glass opacity bilaterally compatible with moderate to severe pulmonary edema.
28 Chest CT: Pulmonary hypertension Massively dilated main pulmonary artery (47mm), enlarged azygos vein, compatible with pulmonary hypertension.
29 Chest CT: Cardiomegaly Cardiomegaly with enlarged right atrium and septum thickening.
30 Summary SLE is chronic autoimmune disease that can affect almost any organ system. Majority of patients with SLE develop pleural or pulmonary disease in the course of their illness. Most common pleuropulmonary manifestations of SLE are: Infections Pleuritis with or without effusion Acute lupus pneumonitis Pulmonary embolism that can lead to pulmonary hypertension
31 References Crestani B. The respiratory system in connective tissue disorders. Allergy, 2005; 60: David A. Lynch MB. Lung disease related to collagen vascular disease. J Thorac Imaging. 2009; 24(4): Tasneem A. Lalani et al. Imaging Findings in Systemic Lupus Erythematosus. RadioGraphics. 2004; 24(4): Lawrence Kenney et al. Lymphocytic interstitial pneumonitis in a woman with tangier s disease. Chest. 2004; 126(4): 977S Pego Reigosa et al. Respiratory manifestations of systemic lupus erythematosus: old and new concepts. Best practice & Research Clinical Rheumatology. 2009; 23: Eun A Kim et al. Interstitial lung diseases associated with collagen vascular diseases: Radiological and histopathologic findings. RadioGraphics. 2002; 22: Bartels C. et al. Systemic Lupus Erythematosus, overview, 09/13/2010
32 Acknowledgements Carol Ridge MD. Emily Hanson Larry Barbaras Thank you
SESSION IV: MECHANISMS OF HUMAN DISEASE: LABORATORY SESSIONS PULMONARY PATHOLOGY I. December 5, 2012
SESSION IV: MECHANISMS OF HUMAN DISEASE: LABORATORY SESSIONS PULMONARY PATHOLOGY I December 5, 2012 FACULTY COPY GOAL: Describe the basic morphologic and pathophysiologic changes in various conditions
More informationSystemic lupus erythematosus and the lung: A pictorial review
Systemic lupus erythematosus and the lung: A pictorial review Poster No.: P-0090 Congress: ESTI 2015 Type: Educational Poster Authors: A. Carvalho, P. Leitão, M. S. C. Rodrigues, B. M. Araujo, N. P. Silva;
More information10/17/2016. Nuts and Bolts of Thoracic Radiology. Objectives. Techniques
Nuts and Bolts of Thoracic Radiology October 20, 2016 Carleen Risaliti Objectives Understand the basics of chest radiograph Develop a system for interpreting chest radiographs Correctly identify thoracic
More informationPulmonary Manifestations of Systemic Lupus Erythematosus 1
Pulmonary Manifestations of Systemic Lupus Erythematosus 1 Kee Hyuk Yang, M.D., Yo Won Choi, M.D., Seok Chol Jeon, M.D., Choong Ki Park, M.D., Kyung in Joo, M.D., Chang Kok Hahm, M.D., Seung Ro Lee, M.D.
More informationDifferential diagnosis
Differential diagnosis Idiopathic pulmonary fibrosis (IPF) is part of a large family of idiopathic interstitial pneumonias (IIP), one of four subgroups of interstitial lung disease (ILD). Differential
More informationSeptember 2014 Imaging Case of the Month. Michael B. Gotway, MD. Department of Radiology Mayo Clinic Arizona Scottsdale, AZ
September 2014 Imaging Case of the Month Michael B. Gotway, MD Department of Radiology Mayo Clinic Arizona Scottsdale, AZ Clinical History: A 57-year-old non-smoking woman presented to her physician as
More informationHRCT in Diffuse Interstitial Lung Disease Steps in High Resolution CT Diagnosis. Where are the lymphatics? Anatomic distribution
Steps in High Resolution CT Diagnosis Pattern of abnormality Distribution of disease Associated findings Clinical history Tomás Franquet MD What is the diagnosis? Hospital de Sant Pau. Barcelona Secondary
More informationPulmonary Manifestations Of Skeletal Disorders
Pulmonary Manifestations Of Skeletal Disorders U. A. Saeed, MBBS FCPS, J. Nair, MBBS MD, R. Khosla, MD FRCR, K. Sayegh, MD FRCPC, J. Kosiuk, MD FRCPC, J. Taylor, MD FRCPC; Department of Radiology, McGill
More informationInteresting Cases. Pulmonary
Interesting Cases Pulmonary 54M with prior history of COPD, hep B/C, and possible history of TB presented with acute on chronic dyspnea, and productive cough Hazy opacity overlying the left hemithorax
More informationARDS - a must know. Page 1 of 14
ARDS - a must know Poster No.: C-1683 Congress: ECR 2016 Type: Authors: Keywords: DOI: Educational Exhibit M. Cristian; Turda/RO Education and training, Edema, Acute, Localisation, Education, Digital radiography,
More informationThe Egyptian Journal of Hospital Medicine (July 2017) Vol.68 (2), Page
The Egyptian Journal of Hospital Medicine (July 2017) Vol.68 (2), Page 1135-1140 Role of High Resolution Computed Tomography in Diagnosis of Interstitial Lung Diseases in Patients with Collagen Diseases
More informationUsual Interstitial pneumonia and Nonspecific Interstitial Pneumonia. Nitra and the Gangs.
Usual Interstitial pneumonia and Nonspecific Interstitial Pneumonia Nitra and the Gangs. บทน ำและบทท ๓, ๑๐, ๑๒, ๑๓, ๑๔, ๑๕, ๑๗ Usual Interstitial Pneumonia (UIP) Most common & basic pathologic pattern
More informationThoracic lung involvement in rheumatoid arthritis: Findings on HRCT
Thoracic lung involvement in rheumatoid arthritis: Findings on HRCT Poster No.: C-2488 Congress: ECR 2015 Type: Educational Exhibit Authors: R. E. Correa Soto, M. J. Martín Sánchez, J. M. Fernandez 1 1
More informationWhen to suspect Wegener Granulomatosis: A radiologic review
When to suspect Wegener Granulomatosis: A radiologic review Poster No.: P-0038 Congress: ESTI 2015 Type: Educational Poster Authors: A. Tilve Gómez, R. Díez Bandera, P. Rodríguez Fernández, M. Garcia Vazquez-Noguerol,
More informationHYPERSENSITIVITY PNEUMONITIS
HYPERSENSITIVITY PNEUMONITIS A preventable fibrosis MOSAVIR ANSARIE MB., FCCP INTERSTITIAL LUNG DISEASES A heterogeneous group of non infectious, non malignant diffuse parenchymal disorders of the lower
More informationAcute and Chronic Lung Disease
KATHOLIEKE UNIVERSITEIT LEUVEN Faculty of Medicine Acute and Chronic Lung Disease W De Wever, JA Verschakelen Department of Radiology, University Hospitals Leuven, Belgium Clinical utility of HRCT To detect
More informationand localized ground glass opacities, or bronchiolar focal or multifocal micronodules;
E1 Chest CT scan and Pneumoniae_YE Claessens et al- Supplementary methods Level of CAP probability according to CT scan - definite CAP: systematic alveolar condensation, or alveolar condensation with peripheral
More informationINTERSTITIAL LUNG DISEASE. Radhika Reddy MD Pulmonary/Critical Care Long Beach VA Medical Center January 5, 2018
INTERSTITIAL LUNG DISEASE Radhika Reddy MD Pulmonary/Critical Care Long Beach VA Medical Center January 5, 2018 Interstitial Lung Disease Interstitial Lung Disease Prevalence by Diagnosis: Idiopathic Interstitial
More informationACUTE RESPIRATORY DISTRESS SYNDROME
ACUTE RESPIRATORY DISTRESS SYNDROME Angel Coz MD, FCCP, DCE Assistant Professor of Medicine UCSF Fresno November 4, 2017 No disclosures OBJECTIVES Identify current trends and risk factors of ARDS Describe
More informationCase 1: Question. 1.1 What is the main pattern of this HRCT? 1. Intralobular line 2. Groundglass opacity 3. Perilymphatic nodule
HRCT WORK SHOP Case 1 Case 1: Question 1.1 What is the main pattern of this HRCT? 1. Intralobular line 2. Groundglass opacity 3. Perilymphatic nodule Case 1: Question 1.2 What is the diagnosis? 1. Hypersensitivity
More informationTB Radiology for Nurses Garold O. Minns, MD
TB Nurse Case Management Salina, Kansas March 31-April 1, 2010 TB Radiology for Nurses Garold O. Minns, MD April 1, 2010 TB Radiology for Nurses Highway Patrol Training Center Salina, KS April 1, 2010
More informationRadiologic-pathologic correlation of pulmonary diseases
The 1578 th Chest Conference/ 3 rd Biennial Clinical- Radiologic-Pathologic Correlation Radiologic-pathologic correlation of pulmonary diseases Harumi Itoh, M.D. University of Fukui, Japan Centriacinar
More informationLung Allograft Dysfunction
Lung Allograft Dysfunction Carlos S. Restrepo M.D. Ameya Baxi M.D. Department of Radiology University of Texas Health San Antonio Disclaimer: We do not have any conflict of interest or financial gain to
More informationTB Intensive Houston, Texas
TB Intensive Houston, Texas October 15-17, 17 2013 Diagnosis of TB: Radiology Rosa M Estrada-Y-Martin, MD MSc FCCP October 16, 2013 Rosa M Estrada-Y-Martin, MD MSc FCCP, has the following disclosures to
More informationElderly Man with Dyspnoea
Asia Pacific Family Medicine, 2004; 3 (1-2): 46-50 RADIOLOGY SERIES Elderly Man with Dyspnoea Wei-Yang LIM Faculty of Medicine National University of Singapore, Singapore Wilfred CG PEH Singapore Health
More informationThoracic Imaging: A Case of Metastatic Adenocarcinoma of Unknown Primary
January 28, 2009 Thoracic Imaging: A Case of Metastatic Adenocarcinoma of Unknown Primary Kristina Mirabeau-Beale, Harvard Medical School Year III Gillian Lieberman, MD Agenda Introduce Patient RS Discuss
More informationAtlas of the Vasculitic Syndromes
CHAPTER e40 Atlas of the Vasculitic Syndromes Carol A. Langford Anthony S. Fauci Diagnosis of the vasculitic syndromes is usually based upon characteristic histologic or arteriographic findings in a patient
More informationAn Introduction to Radiology for TB Nurses
An Introduction to Radiology for TB Nurses Garold O. Minns, MD September 14, 2017 TB Nurse Case Management September 12 14, 2017 EXCELLENCE EXPERTISE INNOVATION Garold O. Minns, MD has the following disclosures
More informationCase 1 : Question. 1.1 What is the intralobular distribution? 1. Centrilobular 2. Perilymphatic 3. Random
Interesting case Case 1 Case 1 : Question 1.1 What is the intralobular distribution? 1. Centrilobular 2. Perilymphatic 3. Random Case 1: Answer 1.1 What is the intralobular distribution? 1. Centrilobular
More information4/17/2010 C ini n ca c l a Ev E a v l a ua u t a ion o n of o ILD U dat a e t e i n I LDs
Update in ILDs Diagnosis 101: Clinical Evaluation April 17, 2010 Jay H. Ryu, MD Mayo Clinic, Rochester MN Clinical Evaluation of ILD Outline General aspects of ILDs Classification of ILDs Clinical evaluation
More informationConnective Tissue Disorder- Associated Interstitial Lung Disease (CTD-ILD) and Updates
Connective Tissue Disorder- Associated Interstitial Lung Disease (CTD-ILD) and Updates Maria Elena Vega, M.D Assistant Professor of Medicine Lewis Katz School of Medicine at Temple University Nothing to
More informationNONE OVERVIEW FINANCIAL DISCLOSURES UPDATE ON IDIOPATHIC PULMONARY FIBROSIS/IPF (UIP) FOR PATHOLOGISTS. IPF = Idiopathic UIP Radiologic UIP Path UIP
UPDATE ON IDIOPATHIC PULMONARY FIBROSIS/IPF () FOR PATHOLOGISTS Thomas V. Colby, M.D. Professor of Pathology (Emeritus) Mayo Clinic Arizona FINANCIAL DISCLOSURES NONE OVERVIEW IPF Radiologic Dx Pathologic
More informationImaging Small Airways Diseases: Not Just Air trapping. Eric J. Stern MD University of Washington
Imaging Small Airways Diseases: Not Just Air trapping Eric J. Stern MD University of Washington What we are discussing SAD classification SAD imaging with MDCT emphasis What is a small airway? Airway with
More informationVariable Pulmonary Manifestations in Hemodialysis Patients 1
Variable Pulmonary Manifestations in Hemodialysis Patients 1 Yookyung Kim, M.D., Sung Shine Shim, M.D., Jung Hee Shin, M.D., Gyu ock Choi, M.D. 2, Kyung Soo Lee, M.D. 3, Chin- Yi, M.D. 3, Yu-Whan Oh, M.D.
More informationRadiological Imaging of Drug-Induced Pulmonary Lesions
Review Article imedpub Journals www.imedpub.com Journal of Clinical Radiology and Case Reports Radiological Imaging of Drug-Induced Pulmonary Lesions D souza M *, Rajiah P, Khan A and Irion K Department
More informationPULMONARY TUBERCULOSIS RADIOLOGY
PULMONARY TUBERCULOSIS RADIOLOGY RADIOLOGICAL MODALITIES Medical radiophotography Radiography Fluoroscopy Linear (conventional) tomography Computed tomography Pulmonary angiography, bronchography Ultrasonography,
More informationOutline Definition of Terms: Lexicon. Traction Bronchiectasis
HRCT OF IDIOPATHIC INTERSTITIAL PNEUMONIAS Disclosures Genentech, Inc. Speakers Bureau Tadashi Allen, MD University of Minnesota Assistant Professor Diagnostic Radiology 10/29/2016 Outline Definition of
More informationType B insulin-resistance syndrome presenting as autoimmune hypoglycemia, associated with systemic lupus erythematosus and interstitial lung disease
CASE REPORT Korean J Intern Med 2013;28:98-102 Type B insulin-resistance syndrome presenting as autoimmune hypoglycemia, associated with systemic lupus erythematosus and interstitial lung disease Seon
More informationARTICLE IN PRESS. Ahuva Grubstein a, Daniele Bendayan b, Ithak Schactman c, Maya Cohen a, David Shitrit b, Mordechai R. Kramer b,
Respiratory Medicine (2005) 99, 948 954 Concomitant upper-lobe bullous emphysema, lower-lobe interstitial fibrosis and pulmonary hypertension in heavy smokers: report of eight cases and review of the literature
More informationSCLERODERMA LUNG DISEASE: WHAT THE PATIENT SHOULD KNOW
SCLERODERMA LUNG DISEASE: WHAT THE PATIENT SHOULD KNOW Lung disease can be a serious complication of scleroderma. The two most common types of lung disease in patients with scleroderma are interstitial
More informationDiagnosis of TB: Radiology David Finlay, MD
TB Intensive Tyler, Texas June 2-4, 2010 Diagnosis of TB: Radiology David Finlay, MD June 3, 2010 2stages stages- Tuberculosis 1. primary infection 2. reactivation, or post primary disease 2 1 Primary
More informationPulmonary Embolism. Thoracic radiologist Helena Lauri
Pulmonary Embolism Thoracic radiologist Helena Lauri 8.5.2017 Statistics 1-2 out of 1000 adults annually are diagnosed with deep vein thrombosis (DVT) and/or pulmonary embolism (PE) About half of patients
More informationDiagnosing Idiopathic Pulmonary Fibrosis on Evidence-Based Guidelines
Diagnosing Idiopathic Pulmonary Fibrosis on Evidence-Based Guidelines Rebecca Keith, MD Assistant Professor, Division of Pulmonary and Critical Care Medicine National Jewish Health, Denver, CO Objectives
More informationFinancial disclosure COMMON DIAGNOSES IN HRCT. High Res Chest HRCT. HRCT Pre test. I have no financial relationships to disclose. Anatomy Nomenclature
Financial disclosure I have no financial relationships to disclose. Douglas Johnson D.O. Cardiothoracic Imaging Gaston Radiology COMMON DIAGNOSES IN HRCT High Res Chest Anatomy Nomenclature HRCT Sampling
More informationThe crazy-paving pattern: A radiological-pathological correlated and illustrated overview
The crazy-paving pattern: A radiological-pathological correlated and illustrated overview Poster No.: C-0827 Congress: ECR 2010 Type: Educational Exhibit Topic: Chest Authors: W. F. M. De Wever, J. Coolen,
More informationTuberculosis: The Essentials
Tuberculosis: The Essentials Kendra L. Fisher, MD, PhD THORACIC TUBERCULOSIS: THE BARE ESSENTIALS Kendra Fisher MD, FRCP (C) Department of Radiology Loma Linda University Medical Center TUBERCULOSIS ()
More informationTests Your Pulmonologist Might Order. Center For Cardiac Fitness Pulmonary Rehab Program The Miriam Hospital
Tests Your Pulmonologist Might Order Center For Cardiac Fitness Pulmonary Rehab Program The Miriam Hospital BASIC ANATOMY OF THE LUNGS Lobes of Lung 3 lobes on the Right lung 2 lobes on the Left Blood
More informationCryptogenic Organizing Pneumonia Diagnosis Approach Based on a Clinical-Radiologic-Pathologic Consensus
Cryptogenic Organizing Pneumonia Diagnosis Approach Based on a Clinical-Radiologic-Pathologic Consensus Poster No.: C-1622 Congress: ECR 2012 Type: Scientific Exhibit Authors: C. Cordero Lares, E. Zorita
More informationUnit II Problem 2 Pathology: Pneumonia
Unit II Problem 2 Pathology: Pneumonia - Definition: pneumonia is the infection of lung parenchyma which occurs especially when normal defenses are impaired such as: Cough reflex. Damage of cilia in respiratory
More informationERDHEIM-CHESTER DISEASE LUNG & HEART ISSUES
ERDHEIM-CHESTER DISEASE LUNG & HEART ISSUES GIULIO CAVALLI, M.D. INTERNAL MEDICINE AND CLINICAL IMMUNOLOGY IRCCS SAN RAFFAELE HOSPITAL VITA-SALUTE SAN RAFFAELE UNIVERSITY MILAN, ITALY cavalli.giulio@hsr.it
More informationPulmonary Function Tests In Patients with Systemic Lupus Erythematosus (SLE)
Pulmonary Function Tests In Patients with Systemic Lupus Erythematosus (SLE) Samiha Samuel, Mona Mohsen, Rasha M. Gamal El-Din, and Hossam Hosny 2 From the Departments of Pediatrics, Children s Hospital,
More informationAtopic Pulmonary Disease: Findings on Thoracic Imaging
July 2003 Atopic Pulmonary Disease: Findings on Thoracic Imaging Rebecca G. Breslow Harvard Medical School Year IV Churg-Strauss Syndrome Hypersensitivity Pneumonitis Asthma Atopic Pulmonary Disease Allergic
More information11/10/2014. Multi-disciplinary Approach to Diffuse Lung Disease: The Imager s Perspective. Radiology
Multi-disciplinary Approach to Diffuse Lung Disease: The Imager s Perspective Radiology Pathology Clinical 1 Role of HRCT Diagnosis Fibrosis vs. inflammation Next step in management Response to treatment
More informationCASE OF THE MONTH. Lung Disease in Rheumatoid Arthritis
CASE OF THE MONTH Lung Disease in Rheumatoid Arthritis 61 year old male Maōri Height: 174 cm Weight: 104.6kg BMI: 34.55 Problems 1. Rheumatoid related interstitial lung disease with UIP pattern 2. Secondary
More informationResident Case Review CHEST. Daria Manos CAR 2016
Resident Case Review CHEST CAR 2016 Daria Manos Disclosure Speakers bureau, Roche CAR 2016 Daria Manos 1. Recognize common and critical chest radiograph and computed tomography signs and use these clues
More informationT he diagnostic evaluation of a patient with
546 REVIEW SERIES Challenges in pulmonary fibrosis? 1: Use of high resolution CT scanning of the lung for the evaluation of patients with idiopathic interstitial pneumonias Michael B Gotway, Michelle M
More informationOctober 2012 Imaging Case of the Month. Michael B. Gotway, MD Associate Editor Imaging. Department of Radiology Mayo Clinic Arizona Scottsdale, AZ
October 2012 Imaging Case of the Month Michael B. Gotway, MD Associate Editor Imaging Department of Radiology Mayo Clinic Arizona Scottsdale, AZ Clinical History: A 65-year-old non-smoking woman presented
More information5/9/2015. Multi-disciplinary Approach to Diffuse Lung Disease: The Imager s Perspective. No, I am not a pulmonologist! Radiology
Multi-disciplinary Approach to Diffuse Lung Disease: The Imager s Perspective No, I am not a pulmonologist! Radiology Pathology Clinical 1 Everyone needs a CT Confidence in diagnosis Definitive HRCT +
More informationReplacement of air with fluid, inflammatory. cells or cellular debris. Parenchymal, Interstitial (Restrictive) and Vascular Diseases.
Parenchymal, Interstitial (Restrictive) and Vascular Diseases Alain C. Borczuk, M.D. Dept of Pathology Replacement of air with fluid, inflammatory cells Pulmonary Edema Pneumonia Hemorrhage Diffuse alveolar
More informationHow to identify interstitial pneumonias.
How to identify interstitial pneumonias. Poster No.: C-0804 Congress: ECR 2014 Type: Educational Exhibit Authors: S. claret loaiza, M. C. Cañete Moslero, R. Carreño Gonzalez, C. de la Torre; Malaga/ES
More informationPULMONARY MEDICINE BOARD REVIEW. Financial Conflicts of Interest. Question #1: Question #1 (Cont.): None. Christopher H. Fanta, M.D.
PULMONARY MEDICINE BOARD REVIEW Christopher H. Fanta, M.D. Pulmonary and Critical Care Division Brigham and Women s Hospital Partners Asthma Center Harvard Medical School Financial Conflicts of Interest
More informationSpectrum of Cystic Lung Disease and its Mimics. Kathleen Jacobs MD and Elizabeth Weihe MD UC San Diego Medical Center, Department of Radiology
Spectrum of Cystic Lung Disease and its Mimics Kathleen Jacobs MD and Elizabeth Weihe MD UC San Diego Medical Center, Department of Radiology No Financial Disclosures Learning Objectives 1. Review the
More informationPneumocystis jirovecci pneumonia: from mild disease to a real disaster. A pictorial review of the different radiologic patterns in acute settings
Pneumocystis jirovecci pneumonia: from mild disease to a real disaster. A pictorial review of the different radiologic patterns in acute settings Poster No.: C-1425 Congress: ECR 2017 Type: Educational
More informationPathologic Assessment of Interstitial Lung Disease
Pathologic Assessment of Interstitial Lung Disease Dry and itchy? It could be eczema or fungal infection. We don t need to worry, the drugs aren t that dangerous. Kirk D. Jones, MD UCSF Dept. of Pathology
More informationJune 2013 Pulmonary Case of the Month: Diagnosis Makes a Difference. Lewis J. Wesselius, MD 1 Henry D. Tazelaar, MD 2
June 2013 Pulmonary Case of the Month: Diagnosis Makes a Difference Lewis J. Wesselius, MD 1 Henry D. Tazelaar, MD 2 Departments of Pulmonary Medicine 1 and Laboratory Medicine and Pathology 2 Mayo Clinic
More informationInterpreting thoracic x-ray of the supine immobile patient: Syllabus
Interpreting thoracic x-ray of the supine immobile patient: Syllabus Johannes Godt Dep. of Radiology and Nuclear Medicine Oslo University Hospital Ullevål NORDTER 2017, Helsinki Content - Why bedside chest
More informationPulmonary Aspergillosis
May 2005 Pulmonary Aspergillosis Nancy Wei, Harvard Medical School, Year III Overview Pulmonary aspergillosis background information Patient presentations Common radiographic findings for each type of
More informationWeb Chapter 3. Image Gallery: Lesion detection on low dose chest CT
Web Chapter 3 Image Gallery: Lesion detection on low dose chest CT Sarabjeet Singh, MD Mannudeep K. Kalra, MD *Eugene J. Mark, MD *James Stone, MD James H. Thrall, MD Department of Radiology and *Department
More informationPulmonary Test Brenda Shinar
Pulmonary Test 2016 Brenda Shinar 1. What is a Renal Tubular Acidosis? What is the difference between the types of RTAs in terms of who gets them and how to diagnose them? Type 1, 2, and 4? Metabolic acidosis
More informationHistopathologic Approach to Interstitial Lung Disease
Histopathologic Approach to Interstitial Lung Disease Kirk D. Jones, MD UCSF Dept of Pathology kirk.jones@ucsf.edu Disclosures I have nothing to disclose 1 Why? Much of interstitial lung disease biopsies
More informationRadiologic Features of The Pulmonary Embolus
January 2003 Radiologic Features of The Pulmonary Embolus Travis McGlothin HMSIII Mr. J is a 51 y.o. male who presented to the BIDMC ED w/ acute onset of: Lft. Hemiparesis slurred speech mild dyspnea mild
More informationHow to Analyse Difficult Chest CT
How to Analyse Difficult Chest CT Complex diseases are:- - Large lesion - Unusual or atypical pattern - Multiple discordant findings Diffuse diseases are:- - Numerous findings in both sides 3 basic steps
More informationCTD-related Lung Disease
13 th Cambridge Chest Meeting King s College, Cambridge April 2015 Imaging of CTD-related Lung Disease Dr Sujal R Desai King s College Hospital, London Disclosure Statement No Disclosures / Conflicts of
More informationRadiologic findings of drug-induced lung disease
Radiologic findings of drug-induced lung disease Poster No.: P-0115 Congress: ESTI 2015 Type: Educational Poster Authors: A. I. C. Santos, A. F. Roque, R. Mamede, L. Oliveira, T. Saldanha; Lisbon/PT Keywords:
More informationINTERSTITIAL LUNG DISEASE Dr. Zulqarnain Ashraf
Indep Rev Jul-Dec 2018;20(7-12) Dr. Zulqarnain Ashraf IR-653 Abstract: ILD is a group of diseases affect interstitium of the lung. Repeated insult to the lung cause the interstitium to be damaged. Similarly
More informationAugust 2018 Imaging Case of the Month: Dyspnea in a 55-Year-Old Smoker. Michael B. Gotway, MD
August 2018 Imaging Case of the Month: Dyspnea in a 55-Year-Old Smoker Michael B. Gotway, MD Department of Radiology Mayo Clinic Arizona Scottsdale, AZ USA Clinical History: A 55 year old woman presented
More informationCystic Lung Disease. Cristopher A. Meyer, MD
Cystic Lung Disease Cristopher A. Meyer, MD Air filled structure with definable wall typically less than 1 mm thick Cris A. Meyer, M.D. Professor of Radiology University of Wisconsin School of Medicine
More informationCase Study #2. Case Study #1 cont 9/28/2011. CAPA 2011 Christy Wilson PA C. LH is 78 yowf with PMHx of metz breast CA presents
Case Study #1 CAPA 2011 Christy Wilson PA C 46 yo female presents with community acquired PNA (CAP). Her condition worsened and she was transferred to the ICU and placed on mechanical ventilation. Describe
More informationIdiopathic interstitial pneumonias (IIPs) are a group of
SYMPOSIA C. Isabela S. Silva, MD, PhD and Nestor L. Müller, MD, PhD Abstract: The idiopathic interstitial pneumonias (IIPs) are a group of diffuse parenchymal lung diseases of unknown etiology characterized
More informationPulmonary manifestations of Rheumatoid Arthritis: what is there waiting to be found?
Pulmonary manifestations of Rheumatoid Arthritis: what is there waiting to be found? Poster No.: C-1795 Congress: ECR 2015 Type: Educational Exhibit Authors: M. S. C. Rodrigues, R. Correia, A. Carvalho,
More informationUnilateral pulmonary oedema, a forgotten presentation.
Unilateral pulmonary oedema, a forgotten presentation. Poster No.: C-2146 Congress: ECR 2018 Type: Educational Exhibit Authors: C. A. Arboleda Vallejo, M. I. carvajal, M. Perez ; Medellin, 1 2 1 1 2 Antioquia/CO,
More informationBronkhorst colloquium Interstitiële longziekten. Katrien Grünberg, klinisch patholoog
Bronkhorst colloquium 2013-2014 Interstitiële longziekten De pathologie achter de CT Katrien Grünberg, klinisch patholoog K.grunberg@vumc.nl Preparing: introduction and 3 cases The introduction on microscopic
More informationManish Powari Regional Training Day 10/12/2014
Manish Powari Regional Training Day 10/12/2014 Large number of different types of Interstitial Lung Disease (ILD). Most are very rare Most patients present with one of a smaller number of commoner diseases
More informationIdiopathic Pulmonary of Care
Chapter 6.1 Living Medical etextbook A Digital Tool at the Point of Care From Projects In Knowledge Pulmonology Idiopathic Pulmonary Fibrosis @Point of Care IPF Case Study: Typical Presentation, Role of
More informationThin-Section CT Findings in 32 Immunocompromised Patients with Cytomegalovirus Pneumonia Who Do Not Have AIDS
Tomás Franquet 1,2 Kyung S. Lee 3 Nestor L. Müller 1 Received January 27, 2003; accepted after revision April 21, 2003. 1 Department of Radiology, Vancouver Hospital and Health Sciences Center and University
More informationIntroduction to Radiology for TB Nurses
Introduction to Radiology for TB Nurses Juzar Ali, MD; FRCP(C); FCCP May 4, 2018 Essential Skills for the TB Nurse Case Manager Little Rock, AR May 3 4, 2017 Juzar Ali, MD; FRCP(C); FCCP has the following
More informationDepartment of Anaesthesiology and Pain Medicine, Seonam University College of Medicine, Namwon, Korea
Case Report pissn 1738-2637 http://dx.doi.org/10.3348/jksr.2013.68.6.473 Rapid Progression of Metastatic Pulmonary Calcification and Alveolar Hemorrhage in a Patient with Chronic Renal Failure and Primary
More informationRadiologic Approach to Smoking Related Interstitial Lung Disease
Radiologic Approach to Smoking Related Interstitial Lung Disease Poster No.: C-1854 Congress: ECR 2013 Type: Educational Exhibit Authors: K.-N. Lee, J.-Y. Han, E.-J. Kang, J. Kang; Busan/KR Keywords: Toxicity,
More informationCommunity Acquired Pneumonia. Abdullah Alharbi, MD, FCCP
Community Acquired Pneumonia Abdullah Alharbi, MD, FCCP A 68 y/ male presented to the ED with SOB and productive coughing for 2 days. Reports poor oral intake since onset due to nausea and intermittent
More informationAn Image Repository for Chest CT
An Image Repository for Chest CT Francesco Frajoli for the Chest CT in Antibody Deficiency Group An Image Repository for Chest CT he Chest CT in Antibody Deficiency Group is an international and interdisciplinary
More informationPleuropulmonary complications 50% incidence. More in patients with more severe chronic articular disease, with high titers of RA factor, patients
Dr Romi Singla Pleuropulmonary complications 50% incidence. More in patients with more severe chronic articular disease, with high titers of RA factor, patients with subcutaneous nodules plus other systemic
More informationObjectives. What is a Chest X Ray? CXR Workshop. Definition (diagnostic tool/internal PE) Types. Cost
Objectives CAPA 2011 Christy Wilson, PA C Georgia Lung Associates Identify the radiographic landmarks on a chest radiograph Recognize identifiers of poor quality on the chest radiograph Outline an approach
More informationChest Radiology Interpretation: Findings of Tuberculosis
Chest Radiology Interpretation: Findings of Tuberculosis Get out your laptops, smart phones or other devices pollev.com/chestradiology Case #1 1 Plombage Pneumonia Cancer 2 Reading the TB CXR Be systematic!
More informationPATIENT CHARACTERISTICS AND PREOPERATIVE DATA (ecrf 1).
PATIENT CHARACTERISTICS AND PREOPERATIVE DATA (ecrf 1). 1 Inform Consent Date: / / dd / Mmm / yyyy 2 Patient identifier: Please enter the 6 digit Patient identification number from your site patient log
More informationA Review of Interstitial Lung Diseases
Outline A Review of Interstitial Lung Diseases Paul J. Wolters, MD Associate Professor Department of Medicine University of California San Francisco Overview of diagnosis in ILD Why it is important Definition/Classification
More informationA Review of Interstitial Lung Diseases. Paul J. Wolters, MD Associate Professor Department of Medicine University of California San Francisco
A Review of Interstitial Lung Diseases Paul J. Wolters, MD Associate Professor Department of Medicine University of California San Francisco Outline Overview of diagnosis in ILD Why it is important Definition/Classification
More informationManagement of Pleural Effusion
Management of Pleural Effusion Development of Pleural Effusion pulmonary capillary pressure (CHF) capillary permeability (Pneumonia) intrapleural pressure (atelectasis) plasma oncotic pressure (hypoalbuminemia)
More informationThe Imaging Analysis of Pulmonary Sarcodiosis
www.cancercellresearch.org ISSN: 2161-2609 Article The Imaging Analysis of Pulmonary Sarcodiosis Xin He, Chuanyu Zhang* Department of Radiology, Affiliated Hospital of Qingdao University, Qingdao, China
More information