VİTEX AGNUS-CASTUS DATABASE

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1 Vitex agnus-castus

2 VİTEX AGNUS-CASTUS DATABASE C 1: Rotem C, Kaplan B. Phyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study. Gynecol Endocrinol Feb;23(2): PMID: [PubMed - indexed for MEDLINE] 2: Hajdu Z, Hohmann J, Forgo P, Martinek T, Dervarics M, Zupko I, Falkay G, Cossuta D, Mathe I. Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents. Phytother Res Apr;21(4): PMID: [PubMed - indexed for MEDLINE] 3: Males Z, Blazevic N, Antolic A. The Essential Oil Composition of Vitex agnus-castus f. rosea Leaves and Flowers. Planta Med Apr;64(3): No abstract available. PMID: [PubMed - in process] 4: Westphal LM, Polan ML, Trant AS. Double-blind, placebo-controlled study of Fertilityblend: a nutritional supplement for improving fertility in women. Clin Exp Obstet Gynecol. 2006;33(4): PMID: [PubMed - indexed for MEDLINE] 5: Tandon VR, Gupta RK. Vitex negundo Linn (VN) leaf extract as an adjuvant therapy to standard antiinflammatory drugs. Indian J Med Res Oct;124(4): PMID: [PubMed - indexed for MEDLINE] 6: Rodriguez-Lopez V, Figueroa-Suarez MZ, Rodriguez T, Aranda E. Insecticidal activity of Vitex mollis. Fitoterapia Jan;78(1):37-9. Epub 2006 Sep 23. PMID: [PubMed - indexed for MEDLINE]

3 7: Sathiamoorthy B, Gupta P, Kumar M, Chaturvedi AK, Shukla PK, Maurya R. New antifungal flavonoid glycoside from Vitex negundo. Bioorg Med Chem Lett Jan 1;17(1): Epub 2006 Oct 5. PMID: [PubMed - indexed for MEDLINE] 8: Zanatta L, de Sousa E, Cazarolli LH, Junior AC, Pizzolatti MG, Szpoganicz B, Silva FR. Effect of crude extract and fractions from Vitex megapotamica leaves on hyperglycemia in alloxan-diabetic rats. J Ethnopharmacol Jan 3;109(1): Epub 2006 Jul 22. PMID: [PubMed - indexed for MEDLINE] 9: Basalo C, Mohn T, Hamburger M. Are extraction methods in quantitative assays of pharmacopoeia monographs exhaustive? A comparison with pressurized liquid extraction. Planta Med Oct;72(12): Epub 2006 Aug 21. PMID: [PubMed - indexed for MEDLINE] 10: Yuan L, Xue M, Liu Y, Wang H. [Toxicity and oviposition-deterrence of Vitex negundo extracts to Plutella xylostella] Ying Yong Sheng Tai Xue Bao Apr;17(4): Chinese. PMID: [PubMed - indexed for MEDLINE] 11: Xie J, Sun B, Zheng F, Yu M. [Technology of extraction of essential oil from leaves of Vitex negundo L. var. heterophylla (Franch.) Rehd. by supercritical CO2 apparatus] Zhong Yao Cai Dec;28(12): Chinese. PMID: [PubMed - indexed for MEDLINE] 12: Azhar-Ul-Haq, Malik A, Khan MT, Anwar-Ul-Haq, Khan SB, Ahmad A, Choudhary MI. Tyrosinase inhibitory lignans from the methanol extract of the roots of Vitex negundo Linn. and their structure-activity relationship. Phytomedicine Mar;13(4): Epub 2005 Jun 27. PMID: [PubMed - indexed for MEDLINE]

4 13: Gallo MB, Beltrame FL, Vieira PC, Cass QB, Fernandes JB, da Silva MF. Quantitative determination of 20-hydroxyecdysone in methanolic extract of twigs from Vitex polygama Cham. J Chromatogr B Analyt Technol Biomed Life Sci Feb 17;832(1): Epub 2006 Jan 26. PMID: [PubMed - indexed for MEDLINE] 14: Webster DE, Lu J, Chen SN, Farnsworth NR, Wang ZJ. Activation of the mu-opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS. J Ethnopharmacol Jun 30;106(2): Epub 2006 Jan 24. PMID: [PubMed - indexed for MEDLINE] 15: Weisskopf M, Schaffner W, Jundt G, Sulser T, Wyler S, Tullberg-Reinert H. A Vitex agnus-castus extract inhibits cell growth and induces apoptosis in prostate epithelial cell lines. Planta Med Oct;71(10): PMID: [PubMed - indexed for MEDLINE] 16: Ladeji O, Udoh FV, Okoye ZS. Activity of aqueous extract of the bark of Vitex doniana on uterine muscle response to drugs. Phytother Res Sep;19(9): PMID: [PubMed - indexed for MEDLINE] 17: Tandon VR, Gupta RK. An experimental evaluation of anticonvulsant activity of Vitex-negundo. Indian J Physiol Pharmacol Apr;49(2): PMID: [PubMed - indexed for MEDLINE] 18: Gupta RK, Tandon VR. Antinociceptive activity of Vitex-negundo Linn leaf extract. Indian J Physiol Pharmacol Apr;49(2): PMID: [PubMed - indexed for MEDLINE]

5 19: Roemheld-Hamm B. Chasteberry. Am Fam Physician Sep 1;72(5): Review. PMID: [PubMed - indexed for MEDLINE] 20: Sharon R, Soroker V, Wesley SD, Zahavi T, Harari A, Weintraub PG. Vitex agnus-castus is a preferred host plant for Hyalesthes obsoletus. J Chem Ecol May;31(5): PMID: [PubMed - indexed for MEDLINE] 21: Li WX, Cui CB, Cai B, Wang HY, Yao XS. Flavonoids from Vitex trifolia L. inhibit cell cycle progression at G2/M phase and induce apoptosis in mammalian cancer cells. J Asian Nat Prod Res Aug;7(4): PMID: [PubMed - indexed for MEDLINE] 22: Nathan SS, Kalaivani K, Murugan K. Effect of biopesticides on the lactate dehydrogenase (LDH) of the rice leaffolder, Cnaphalocrocis medinalis (Guenee) (Insecta: Lepidoptera: Pyralidae). Ecotoxicol Environ Saf Sep;65(1): Epub 2005 Jul 19. PMID: [PubMed - indexed for MEDLINE] 23: Sridhar C, Rao KV, Subbaraju GV. Flavonoids, triterpenoids and a lignan from Vitex altissima. Phytochemistry Jul;66(14): PMID: [PubMed - indexed for MEDLINE] 24: Nathan SS, Chung PG, Murugan K. Combined effect of biopesticides on the digestive enzymatic profiles of Cnaphalocrocis medinalis (Guenee) (the rice leaffolder) (Insecta: Lepidoptera: Pyralidae). Ecotoxicol Environ Saf Jul;64(3): Epub 2005 Jun 8. PMID: [PubMed - indexed for MEDLINE]

6 25: Agunu A, Yusuf S, Andrew GO, Zezi AU, Abdurahman EM. Evaluation of five medicinal plants used in diarrhoea treatment in Nigeria. J Ethnopharmacol Oct 3;101(1-3): PMID: [PubMed - indexed for MEDLINE] 26: Mancho P, Edwards QT. Chaste tree for premenstrual syndrome. An evolving therapy in the United States. Adv Nurse Pract May;13(5):43-4, 46. Review. No abstract available. PMID: [PubMed - indexed for MEDLINE] 27: Wang HY, Cai B, Cui CB, Zhang DY, Yang BF. [Vitexicarpin, a flavonoid from Vitex trifolia L., induces apoptosis in K562 cells via mitochondria-controlled apoptotic pathway] Yao Xue Xue Bao Jan;40(1): Chinese. PMID: [PubMed - indexed for MEDLINE] 28: Ohyama K, Akaike T, Imai M, Toyoda H, Hirobe C, Bessho T. Human gastric signet ring carcinoma (KATO-III) cell apoptosis induced by Vitex agnuscastus fruit extract through intracellular oxidative stress. Int J Biochem Cell Biol Jul;37(7): PMID: [PubMed - indexed for MEDLINE] 29: Yoshioka T, Inokuchi T, Fujioka S, Kimura Y. Phenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia. Z Naturforsch [C] Jul-Aug;59(7-8): PMID: [PubMed - indexed for MEDLINE] 30: Daniele C, Thompson Coon J, Pittler MH, Ernst E. Vitex agnus castus: a systematic review of adverse events. Drug Saf. 2005;28(4): Review. PMID: [PubMed - indexed for MEDLINE]

7 31: Jimenez-Ferrer JE, Perez-Teran YY, Roman-Ramos R, Tortoriello J. Antitoxin activity of plants used in Mexican traditional medicine against scorpion poisoning. Phytomedicine Jan;12(1-2): PMID: [PubMed - indexed for MEDLINE] 32: Mehlhorn H, Schmahl G, Schmidt J. Extract of the seeds of the plant Vitex agnus castus proven to be highly efficacious as a repellent against ticks, fleas, mosquitoes and biting flies. Parasitol Res Mar;95(5): Epub 2005 Jan 29. PMID: [PubMed - indexed for MEDLINE] 33: Li WX, Cui CB, Cai B, Yao XS. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res Apr;7(2): PMID: [PubMed - indexed for MEDLINE] 34: Ono M, Nishida Y, Masuoka C, Li JC, Okawa M, Ikeda T, Nohara T. Lignan derivatives and a norditerpene from the seeds of Vitex negundo. J Nat Prod Dec;67(12): PMID: [PubMed - indexed for MEDLINE] 35: Sridhar C, Subbaraju GV, Venkateswarlu Y, Venugopal RT. New acylated iridoid glucosides from Vitex altissima. J Nat Prod Dec;67(12): PMID: [PubMed - indexed for MEDLINE] 36: Kiuchi F, Matsuo K, Ito M, Qui TK, Honda G. New norditerpenoids with trypanocidal activity from Vitex trifolia. Chem Pharm Bull (Tokyo) Dec;52(12): PMID: [PubMed - indexed for MEDLINE]

8 37: Singleton ML. Saving our endangered midwifery allies. Midwifery Today Int Midwife Autumn;(71):32-5. Review. No abstract available. PMID: [PubMed - indexed for MEDLINE] 38: Azhar-Ul-Haq, Malik A, Anis I, Khan SB, Ahmed E, Ahmed Z, Nawaz SA, Choudhary MI. Enzyme inhibiting lignans from Vitex negundo. Chem Pharm Bull (Tokyo) Nov;52(11): PMID: [PubMed - indexed for MEDLINE] 39: Kobayakawa J, Sato-Nishimori F, Moriyasu M, Matsukawa Y. G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.). Cancer Lett May 10;208(1): PMID: [PubMed - indexed for MEDLINE] 40: Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic D, Mahady G, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry). Phytomedicine Jan;11(1): PMID: [PubMed - indexed for MEDLINE] 41: Das S, Parveen S, Kundra CP, Pereira BM. Reproduction in male rats is vulnerable to treatment with the flavonoid-rich seed extracts of Vitex negundo. Phytother Res Jan;18(1):8-13. PMID: [PubMed - indexed for MEDLINE]

9 42: Halaska M, Beles P, Gorkow C, Sieder C. Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: results of a placebo-controlled double-blind study. Breast Aug;8(4): PMID: [PubMed] 43: Jarry H, Spengler B, Porzel A, Schmidt J, Wuttke W, Christoffel V. Evidence for estrogen receptor beta-selective activity of Vitex agnus-castus and isolated flavones. Planta Med Oct;69(10): PMID: [PubMed - indexed for MEDLINE] 44: Wardle DA, Yeates GW, Barker GM, Bellingham PJ, Bonner KI, Williamson WM. Island biology and ecosystem functioning in epiphytic soil communities. Science Sep 19;301(5640): PMID: [PubMed - indexed for MEDLINE] 45: Kuruuzum-Uz A, Stroch K, Demirezer LO, Zeeck A. Glucosides from Vitex agnus-castus. Phytochemistry Aug;63(8): PMID: [PubMed - indexed for MEDLINE] 46: Dharmasiri MG, Jayakody JR, Galhena G, Liyanage SS, Ratnasooriya WD. Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex negundo. J Ethnopharmacol Aug;87(2-3): PMID: [PubMed - indexed for MEDLINE] 47: Chopin Lucks B. Vitex agnus castus essential oil and menopausal balance: a research update [Complementary Therapies in Nursing and Midwifery 8 (2003) ]. Complement Ther Nurs Midwifery Aug;9(3): PMID: [PubMed - indexed for MEDLINE]

10 48: Diaz F, Chavez D, Lee D, Mi Q, Chai HB, Tan GT, Kardono LB, Riswan S, Fairchild CR, Wild R, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. J Nat Prod Jun;66(6): PMID: [PubMed - indexed for MEDLINE] 49: Wuttke W, Jarry H, Christoffel V, Spengler B, Seidlova-Wuttke D. Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications. Phytomedicine May;10(4): Review. PMID: [PubMed - indexed for MEDLINE] 50: Girman A, Lee R, Kligler B. An integrative medicine approach to premenstrual syndrome. Am J Obstet Gynecol May;188(5 Suppl):S Review. PMID: [PubMed - indexed for MEDLINE] 51: Tesch BJ. Herbs commonly used by women: an evidence-based review. Am J Obstet Gynecol May;188(5 Suppl):S Review. PMID: [PubMed - indexed for MEDLINE] 52: Alam MI, Gomes A. Snake venom neutralization by Indian medicinal plants (Vitex negundo and Emblica officinalis) root extracts. J Ethnopharmacol May;86(1): PMID: [PubMed - indexed for MEDLINE] 53: Atmaca M, Kumru S, Tezcan E. Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder. Hum Psychopharmacol Apr;18(3): PMID: [PubMed - indexed for MEDLINE]

11 54: Chandramu C, Manohar RD, Krupadanam DG, Dashavantha RV. Isolation, characterization and biological activity of betulinic acid and ursolic acid from Vitex negundo L. Phytother Res Feb;17(2): PMID: [PubMed - indexed for MEDLINE] 55: Xu H, Fabricant DS, Piersen CE, Bolton JL, Pezzuto JM, Fong H, Totura S, Farnsworth NR, Constantinou AI. A preliminary RAPD-PCR analysis of Cimicifuga species and other botanicals used for women's health. Phytomedicine Dec;9(8): PMID: [PubMed - indexed for MEDLINE] 56: Tesch BJ. Herbs commonly used by women: an evidence-based review. Dis Mon Oct;48(10): Review. PMID: [PubMed - indexed for MEDLINE] 57: Ohyama K, Akaike T, Hirobe C, Yamakawa T. Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth. Biol Pharm Bull Jan;26(1):10-8. PMID: [PubMed - indexed for MEDLINE] 58: Alam G, Wahyuono S, Ganjar IG, Hakim L, Timmerman H, Verpoorte R. Tracheospasmolytic activity of viteosin-a and vitexicarpin isolated from vitex trifolia. Planta Med Nov;68(11): PMID: [PubMed - indexed for MEDLINE] 59: Suksamrarn A, Kumpun S, Yingyongnarongkul BE. Ecdysteroids of Vitex scabra stem bark. J Nat Prod Nov;65(11): PMID: [PubMed - indexed for MEDLINE]

12 60: Russell L, Hicks GS, Low AK, Shepherd JM, Brown CA. Phytoestrogens: a viable option? Am J Med Sci Oct;324(4): Review. PMID: [PubMed - indexed for MEDLINE] 61: Lucks BC, Sorensen J, Veal L. Vitexagnus-castus essential oil and menopausal balance: a self-care survey. Complement Ther Nurs Midwifery Aug;8(3): PMID: [PubMed - indexed for MEDLINE] 62: Gorkow C, Wuttke W, Marz RW. [Effectiveness of Vitex agnus-castus preparations] Wien Med Wochenschr. 2002;152(15-16): German. PMID: [PubMed - indexed for MEDLINE] 63: Ko WG, Kang TH, Lee SJ, Kim YC, Lee BH. Effects of luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells. Phytother Res May;16(3): PMID: [PubMed - indexed for MEDLINE] 64: Suksamrarn A, Kumpun S, Kirtikara K, Yingyongnarongkul B, Suksamrarn S. Iridoids with anti-inflammatory activity from Vitex peduncularis. Planta Med Jan;68(1):72-3. PMID: [PubMed - indexed for MEDLINE] 65: Goncalves JL, Leitao SG, Monache FD, Miranda MM, Santos MG, Romanos MT, Wigg MD. In vitro antiviral effect of flavonoid-rich extracts of Vitex polygama (Verbenaceae) against acyclovir-resistant herpes simplex virus type 1. Phytomedicine Nov;8(6): PMID: [PubMed - indexed for MEDLINE]

13 66: Carr M. Selections from current literature. Treatments for premenstrual dysphoric disorder. Fam Pract Dec;18(6): No abstract available. PMID: [PubMed - indexed for MEDLINE] 67: Born L, Steiner M. Current management of premenstrual syndrome and premenstrual dysphoric disorder. Curr Psychiatry Rep Dec;3(6): Review. PMID: [PubMed - indexed for MEDLINE] 68: Hossain MM, Paul N, Sohrab MH, Rahman E, Rashid MA. Antibacterial activity of Vitex trifolia. Fitoterapia Aug;72(6): PMID: [PubMed - indexed for MEDLINE] 69: Ko WG, Kang TH, Lee SJ, Kim YC, Lee BH. Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells. Phytother Res Sep;15(6): PMID: [PubMed - indexed for MEDLINE] 70: [No authors listed] Herbal treatment for PMS? Harv Womens Health Watch May;8(9):7. No abstract available. PMID: [PubMed - indexed for MEDLINE] 71: Liu J, Burdette JE, Xu H, Gu C, van Breemen RB, Bhat KP, Booth N, Constantinou AI, Pezzuto JM, Fong HH, Farnsworth NR, Bolton JL. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem May;49(5): PMID: [PubMed - indexed for MEDLINE]

14 72: Huddleston M, Jackson EA. Is an extract of the fruit of agnus castus (chaste tree or chasteberry) effective for prevention of symptoms of premenstrual syndrome (PMS)? J Fam Pract Apr;50(4):298. No abstract available. PMID: [PubMed - indexed for MEDLINE] 73: dos Santos TC, Delle Monache F, Leitao SG. Ecdysteroids from two Brazilian Vitex species. Fitoterapia Mar;72(3): PMID: [PubMed - indexed for MEDLINE] 74: Zhang T, Li T, Jiang W, Ma Y, Li C, Zhou J. [Influence of fry-processing on outward character and inner quality of volatile oil containing drugs such as fructus Viticis, etc.] Zhongguo Zhong Yao Za Zhi Jan;23(1):22-4, 62. Chinese. PMID: [PubMed - indexed for MEDLINE] 75: Ono M, Yamamoto M, Yanaka T, Ito Y, Nohara T. Ten new labdane-type diterpenes from the fruit of Vitex rotundifolia. Chem Pharm Bull (Tokyo) Jan;49(1):82-6. PMID: [PubMed - indexed for MEDLINE] 76: Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study. BMJ Jan 20;322(7279): PMID: [PubMed - indexed for MEDLINE] 77: Ono M, Sawamura H, Ito Y, Mizuki K, Nohara T. Diterpenoids from the fruits of Vitex trifolia. Phytochemistry Dec;55(8): PMID: [PubMed - indexed for MEDLINE]

15 78: Berger D, Schaffner W, Schrader E, Meier B, Brattstrom A. Efficacy of Vitex agnus castus L. extract Ze 440 in patients with pre-menstrual syndrome (PMS). Arch Gynecol Obstet Nov;264(3): PMID: [PubMed - indexed for MEDLINE] 79: Meier B, Berger D, Hoberg E, Sticher O, Schaffner W. Pharmacological activities of Vitex agnus-castus extracts in vitro. Phytomedicine Oct;7(5): PMID: [PubMed - indexed for MEDLINE] 80: Bergmann J, Luft B, Boehmann S, Runnebaum B, Gerhard I. [The efficacy of the complex medication Phyto-Hypophyson L in female, hormonerelated sterility. A randomized, placebo-controlled clinical double-blind study] Forsch Komplementarmed Klass Naturheilkd Aug;7(4): German. PMID: [PubMed - indexed for MEDLINE] 81: Tschudin S, Huber R. [Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: Results of a placebo-controlled double-blind study. Breast 1999;8: ] Forsch Komplementarmed Klass Naturheilkd Jun;7(3): German. No abstract available. PMID: [PubMed - indexed for MEDLINE] 82: Raja N, Albert S, Ignacimuthu S. Effect of solvent residues of Vitex negundo Linn. and Cassia fistula Linn. on pulse beetle, Callosobruchus maculatus Fab. and its larval parasitoid, Dinarmus vagabundus (Timberlake). Indian J Exp Biol Mar;38(3): PMID: [PubMed - indexed for MEDLINE] 83: Hoberg E, Meier B, Sticher O. Quantitative high performance liquid chromatographic analysis of diterpenoids in agni-casti fructus. Planta Med May;66(4): PMID: [PubMed - indexed for MEDLINE]

16 84: Sorensen JM, Katsiotis ST. Parameters influencing the yield and composition of the essential oil from Cretan Vitex agnus-castus fruits. Planta Med Apr;66(3): PMID: [PubMed - indexed for MEDLINE] 85: Suksamrarn A, Promrangsan N, Jintasirikul A. Highly oxygenated ecdysteroids from Vitex canescens root bark. Phytochemistry Apr;53(8): PMID: [PubMed - indexed for MEDLINE] 86: Loch EG, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Womens Health Gend Based Med Apr;9(3): PMID: [PubMed - indexed for MEDLINE] 87: Gupta M, Mazumder UK, Bhawal SR. CNS activity of Vitex negundo Linn. in mice. Indian J Exp Biol Feb;37(2): PMID: [PubMed - indexed for MEDLINE] 88: Hernandez MM, Heraso C, Villarreal ML, Vargas-Arispuro I, Aranda E. Biological activities of crude plant extracts from Vitex trifolia L. (Verbenaceae). J Ethnopharmacol Oct;67(1): PMID: [PubMed - indexed for MEDLINE] 89: Halaska M, Raus K, Beles P, Martan A, Paithner KG. [Treatment of cyclical mastodynia using an extract of Vitex agnus castus: results of a doubleblind comparison with a placebo] Ceska Gynekol Oct;63(5): PMID: [PubMed - indexed for MEDLINE]

17 90: Veal L. Complementary therapy and infertility: an Icelandic perspective. Complement Ther Nurs Midwifery Feb;4(1):3-6. Review. PMID: [PubMed - indexed for MEDLINE] 91: Hirobe C, Qiao ZS, Takeya K, Itokawa H. Cytotoxic flavonoids from Vitex agnus-castus. Phytochemistry Oct;46(3): PMID: [PubMed - indexed for MEDLINE] 92: Zwaving JH, Bos R. Composition of the Essential Fruit Oil of Vitex agnus-castus. Planta Med Feb;62(1):83-4. PMID: [PubMed - in process] 93: Cahill DJ, Fox R, Wardle PG, Harlow CR. Multiple follicular development associated with herbal medicine. Hum Reprod Aug;9(8): PMID: [PubMed - indexed for MEDLINE] 94: Milewicz A, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H. [Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study] Arzneimittelforschung Jul;43(7): German. PMID: [PubMed - indexed for MEDLINE] 95: Sliutz G, Speiser P, Schultz AM, Spona J, Zeillinger R. Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res May;25(5): PMID: [PubMed - indexed for MEDLINE]

18 96: Hobbs C. The chaste tree: Vitex agnus castus. Pharm Hist. 1991;33(1): No abstract available. PMID: [PubMed - indexed for MEDLINE] 97: Gorler K, Oehlke D, Soicke H. [Iridoidfuhrung von Vitex agnus-castus.] Planta Med Dec;51(6): German. No abstract available. PMID: [PubMed - as supplied by publisher] 98: Wollenweber E, Mann K. [Flavonols from Fruits of Vitex agnus castus.] Planta Med Jun;48(6): German. No abstract available. PMID: [PubMed - in process] 99: Amann W. [Amenorrhea. Favorable effect of Agnus castus (Agnolyt) on amenorrhea] ZFA (Stuttgart) Feb 10;58(4): German. No abstract available. PMID: [PubMed - indexed for MEDLINE] 100: HAENSEL R, RIMPLER H. [ISOLATION OF HOMO-ORIENTINE FROM THE LEAVES OF VITEX AGNUS CASTUS L.] Arch Pharm (Weinheim) Sep;296: German. No abstract available. PMID: [PubMed - indexed for MEDLINE] 101: SIRAIT M, RIMPLER H, HAENSEL R. [Flavonoids from Vitex agnus castus L.] Experientia Feb 15;18:72. German. No abstract available. PMID: [PubMed - indexed for MEDLINE]

19 102: WINDE E, HAENSEL R. [Pseudoindican from Vitex agnus castus L.] Arch Pharm May;293/65: German. No abstract available. PMID: [PubMed - indexed for MEDLINE] C 1: Roemheld-Hamm B. Chasteberry. Am Fam Physician Sep 1;72(5): Review. PMID: [PubMed - indexed for MEDLINE] 2: Mancho P, Edwards QT. Chaste tree for premenstrual syndrome. An evolving therapy in the United States. Adv Nurse Pract May;13(5):43-4, 46. Review. No abstract available. PMID: [PubMed - indexed for MEDLINE] 3: Daniele C, Thompson Coon J, Pittler MH, Ernst E. Vitex agnus castus: a systematic review of adverse events. Drug Saf. 2005;28(4): Review. PMID: [PubMed - indexed for MEDLINE] 4: Singleton ML. Saving our endangered midwifery allies. Midwifery Today Int Midwife Autumn;(71):32-5. Review. No abstract available. PMID: [PubMed - indexed for MEDLINE] 5: Wuttke W, Jarry H, Christoffel V, Spengler B, Seidlova-Wuttke D. Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications. Phytomedicine May;10(4): Review. PMID: [PubMed - indexed for MEDLINE] 6: Girman A, Lee R, Kligler B. An integrative medicine approach to premenstrual syndrome. Am J Obstet Gynecol May;188(5 Suppl):S Review. PMID: [PubMed - indexed for MEDLINE]

20 7: Tesch BJ. Herbs commonly used by women: an evidence-based review. Am J Obstet Gynecol May;188(5 Suppl):S Review. PMID: [PubMed - indexed for MEDLINE] 8: Tesch BJ. Herbs commonly used by women: an evidence-based review. Dis Mon Oct;48(10): Review. PMID: [PubMed - indexed for MEDLINE] 9: Russell L, Hicks GS, Low AK, Shepherd JM, Brown CA. Phytoestrogens: a viable option? Am J Med Sci Oct;324(4): Review. PMID: [PubMed - indexed for MEDLINE] 10: Born L, Steiner M. Current management of premenstrual syndrome and premenstrual dysphoric disorder. Curr Psychiatry Rep Dec;3(6): Review. PMID: [PubMed - indexed for MEDLINE] 11: Veal L. Complementary therapy and infertility: an Icelandic perspective. Complement Ther Nurs Midwifery Feb;4(1):3-6. Review. PMID: [PubMed - indexed for MEDLINE]

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