PHARMACOGNOSY. 4. Reserpine is indicated in: A. gastroduodenal ulcer B. depression C. arterial hypertension D. schizophrenia E. pregnancy.
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1 PHARMACOGNOSY 1. The following structural features are essential for the spasmolytic activity of atropine: A. tropanol ring B. pseudotropanol ring C. morphinan ring D. quaternary nitrogen atom E. integrity of ester bond. 2. The following lisergic alkaloids have ocitocic effects: A. ergometrine B. dihydroergotamine C. ergometrinine D. ergotamine E. dihydroergotoxine 3. Morphine: A. induces miosis B. causes pharmacodependence C. is a peptidic derivative D. has spasmolytic activity E. has diuretic activity. 4. Reserpine is indicated in: A. gastroduodenal ulcer B. depression C. arterial hypertension D. schizophrenia E. pregnancy.
2 5. Ipecacuanhae radix contains alkaloids: A. derivatives of emetine B. derivatives of amino alcohol structure C. having an isoquinoline ring D. derivatives of ornithine E. derivatives of phenylalanine. 6. The analgesic activity of morphine is determined by: A. tyrosine terminal residue B. epoxy bond at C15-C16 C. ketone group at C3 D. tertiary amine group E. primary amine group. 7. In therapeutic doses, codeine: A. has antitussive activity B. counteracts the effect of analgesics C. decreases respiration D. is a weak analgesic E. is indicated in organophosphorus insecticide poisoning. 8. Rauwolfiae radix contains: A. scopolamine B. raubasine C. reserpine D. emetine E. serpentine. 9. Atropine: A. is used in therapeutics as antispastic agent B. is a quaternary alkaloid C. causes mydriasis D. has antitumor activity E. is found in Opium.
3 10. Hydrogenation of the peptide alkaloids of Secale cornutum causes: A. increase of ocitocic activity B. disappearance of ocitocic activity C. decrease of toxicity D. increase of adrenolitic effect E. appearance of sedative effect. 11. Emetine acts as an: A. antiemetic agent B. antihypertensive agent C. emetic agent D. antiamoebian agent E. expectorant agent. 12. The main contraindications of the tropane alkaloids are: A. glaucoma B. inflammations of iris C. prostate adenoma D. Parkinson's disease E. Amanita mushrooms poisoning. 13. Papaverine: A. has analgesic activity B. has a morphinan ring C. causes pharmacodependence D. has spasmolytic activity E. has coronarodilating activity. 14. Secale cornutum: A. is obtained from the immature capsules of Papaver somniferum B. is administered orally C. contains codeine D. consists of the sclerots of Claviceps purpurea fungus E. has a sweet taste, initially, than pungent and unpleasant.
4 15. The following alkaloids have antimicrobial effects: A. cheleritrine B. belladonnine C. narcotine D. sanguinarine E. clavinic derivatives. 16. The total alkaloidic content from Chelidonii herba: A. has sialagogue effects B. causes constipation C. has colecistokinetic effects D. stimulates pancreatic secretion E. has a hypotensive effect. 17. Which of the following alkaloids have antispastic/spasmolytic effects: A. atropine B. chelidonine C. hyoscyamine D. noscapine E. reserpine 18. Belladonnae folium: A. consists of the leaves collected from Atropa belladonna B. consists of the latex of the stems of Atropa belladonna C. contains hyoscyamine as major alkaloid (the fresh leaf) D. contains atropine as major alkaloid (the fresh leaf) E. contains scopolamine. 19. Opium: A. consists of the latex collected from Chelidonii herba B. has proteolytic effects C. is used to remove warts D. causes pharmacodependence E. has antidiarrheal activity.
5 20. Dihydroergotoxine: A. is recommended in orthostatic hypotension B. has vasoconstrictor effects C. is recommened as antimigraine agent D. is recommended in brain vascular disorders E. has antihypertensive effects. 21. The following alkaloids have antitussive effects: A. scopolamine B. narcotine C. codeine D. papaverine E. sanguinarine. 22. In bronchial disorders, Ipecacuanhae radix is administered as: A. tincture B. syrup C. decoction D. infusion E. only emetine as pure substance is used. 23. Nalorfine: A. causes pharmacodependence B. is an antidote for morphine poisoning in case of toxicomania C. does not cause pharmacodependence D. has an analgesic effect E. is a synthetic compound.
6 24. The following substances are quaternary colored alkaloids: A. narceine B. sanguinarine C. berberine D. serpentine E. cheleritrine. 25. The following alkaloids stimulate the brain circulation: A. ajmalicine B. ergotamine C. ergotoxine D. dihydroergocristine E. dihydroergotamine.
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