SAFETY DATA SHEET. Creation Date 08-Jan-2007 Revision Date 19-Jan-2018 Revision Number Identification

Transcription

1 SAFETY DATA SHEET Creation Date 08-Jan-2007 Revision Number 4 Product Name Cat No. : 1. Identification 1-Hexadecylpyridinium chloride monohydrate AC ; AC ; AC ; AC ; AC CAS-No Synonyms Cetylpyridinium chloride monohydrate Recommended Use Uses advised against Laboratory chemicals. Not for food, drug, pesticide or biocidal product use Details of the supplier of the safety data sheet Company Fisher Scientific One Reagent Lane Fair Lawn, NJ Tel: (201) Acros Organics One Reagent Lane Fair Lawn, NJ Emergency Telephone Number For information US call: ACROS-01 / Europe call: Emergency Number US: / Europe: CHEMTREC Tel. No.US: / Europe: Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR ) Acute oral toxicity Category 3 Acute Inhalation Toxicity - Dusts and Mists Category 2 Skin Corrosion/irritation Category 2 Serious Eye Damage/Eye Irritation Category 1 Specific target organ toxicity (single exposure) Category 3 Target Organs - Respiratory system. Label Elements Signal Word Danger Hazard Statements Toxic if swallowed Causes skin irritation Causes serious eye damage Fatal if inhaled May cause respiratory irritation Page 1 / 7

2 Precautionary Statements Prevention Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Do not breathe dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area Wear respiratory protection Wear protective gloves/protective clothing/eye protection/face protection Inhalation IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Immediately call a POISON CENTER or doctor/physician Call a POISON CENTER or doctor/physician if you feel unwell Skin IF ON SKIN: Wash with plenty of soap and water If skin irritation occurs: Get medical advice/attention Take off contaminated clothing and wash before reuse Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing Immediately call a POISON CENTER or doctor/physician Ingestion IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician Rinse mouth Storage Store locked up Store in a well-ventilated place. Keep container tightly closed Disposal Dispose of contents/container to an approved waste disposal plant Hazards not otherwise classified (HNOC) Very toxic to aquatic life with long lasting effects 3. Composition/Information on Ingredients Component CAS-No Weight % Pyridinium, cetyl-, chloride monohydrate >95 Pyridinium, 1-hexadecyl-, chloride First-aid measures General Advice Eye Contact Skin Contact Inhalation Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. Move to fresh air. If not breathing, give artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a Page 2 / 7

3 pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required. Ingestion Most important symptoms and effects Notes to Physician Suitable Extinguishing Media Unsuitable Extinguishing Media Flash Point Method - Do not induce vomiting. Call a physician or Poison Control Center immediately. Causes severe eye damage. Treat symptomatically 5. Fire-fighting measures Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Autoignition Temperature Explosion Limits Upper Lower Sensitivity to Mechanical Impact Sensitivity to Static Discharge Specific Hazards Arising from the Chemical Do not allow run-off from fire fighting to enter drains or water courses. Hazardous Combustion Products Hydrogen chloride gas Nitrogen oxides (NOx) Carbon monoxide (CO) Carbon dioxide (CO2) Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors. NFPA Health 3 Flammability 1 Instability 1 Physical hazards N/A Personal Precautions Environmental Precautions 6. Accidental release measures Ensure adequate ventilation. Use personal protective equipment. Avoid dust formation. Keep people away from and upwind of spill/leak. Evacuate personnel to safe areas. Do not flush into surface water or sanitary sewer system. Do not allow material to contaminate ground water system. Prevent product from entering drains. Local authorities should be advised if significant spillages cannot be contained. Methods for Containment and Clean Sweep up or vacuum up spillage and collect in suitable container for disposal. Avoid dust Up formation. Handling Storage Exposure Guidelines 7. Handling and storage Do not get in eyes, on skin, or on clothing. Wear personal protective equipment. Avoid dust formation. Use only under a chemical fume hood. Do not breathe vapors/dust. Do not ingest. Keep in a dry, cool and well-ventilated place. Keep container tightly closed. 8. Exposure controls / personal protection This product does not contain any hazardous materials with occupational exposure limitsestablished by the region specific regulatory bodies. Page 3 / 7

4 Engineering Measures Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Personal Protective Equipment Eye/face Protection Skin and body protection Respiratory Protection Hygiene Measures Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR or European Standard EN166. Long sleeved clothing. Follow the OSHA respirator regulations found in 29 CFR or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Handle in accordance with good industrial hygiene and safety practice. 9. Physical and chemical properties Physical State Powder Solid Appearance White Odor Characteristic Odor Threshold ph % aq.sol Melting Point/Range C / F Boiling Point/Range Flash Point Evaporation Rate Flammability (solid,gas) Flammability or explosive limits Upper Lower Vapor Pressure Vapor Density Specific Gravity Solubility Soluble in water Partition coefficient; n-octanol/water Autoignition Temperature Decomposition Temperature 234 C Viscosity Molecular Formula C21 H38 Cl N. H2 O Molecular Weight Stability and reactivity Reactive Hazard Stability Conditions to Avoid Incompatible Materials None known, based on information available Hygroscopic. Incompatible products. Exposure to moist air or water. Strong oxidizing agents, Acids, Acid anhydrides, Acid chlorides Hazardous Decomposition Products Hydrogen chloride gas, Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2) Hazardous Polymerization. Page 4 / 7

5 Hazardous Reactions Acute Toxicity None under normal processing. 11. Toxicological information Product Information Component Information Component LD50 Oral LD50 Dermal LC50 Inhalation Pyridinium, 1-hexadecyl-, chloride LD50 = 200 mg/kg (Rat) LD50 >5000 mg/kg (Rat) LC50 = mg/l/4h (Rat) Toxicologically Synergistic Products Delayed and immediate effects as well as chronic effects from short and long-term exposure Irritation Sensitization Carcinogenicity Risk of serious damage to eyes Irritating to respiratory system and skin The table below indicates whether each agency has listed any ingredient as a carcinogen. Component CAS-No IARC NTP ACGIH OSHA Mexico Pyridinium, cetyl-, Not listed Not listed Not listed Not listed Not listed chloride monohydrate Pyridinium, 1-hexadecyl-, chloride Not listed Not listed Not listed Not listed Not listed Mutagenic Effects Reproductive Effects Developmental Effects Teratogenicity STOT - single exposure STOT - repeated exposure Aspiration hazard Symptoms / effects,both acute and delayed Endocrine Disruptor Information Other Adverse Effects... Respiratory system None known The toxicological properties have not been fully investigated. 12. Ecological information Ecotoxicity Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. The product contains following substances which are hazardous for the environment. Component Freshwater Algae Freshwater Fish Microtox Water Flea Pyridinium, cetyl-, chloride monohydrate Not listed LC50: 0.01 mg/l/96h (Cyprinus carpio) Not listed EC50: 9.18 mg/l/48h Persistence and Degradability Bioaccumulation/ Accumulation Mobility Component. Will likely be mobile in the environment due to its water solubility. log Pow Page 5 / 7

6 Pyridinium, cetyl-, chloride monohydrate 1.7 Waste Disposal Methods 13. Disposal considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. 14. Transport information DOT Proper Shipping Name Toxic solid, organic, n.o.s Proper technical name Pyridinium, cetyl-, chloride monohydrate TDG Proper Shipping Name TOXIC SOLID, ORGANIC, N.O.S. IATA Proper Shipping Name TOXIC SOLID, ORGANIC, N.O.S. IMDG/IMO Proper Shipping Name TOXIC SOLID, ORGANIC, N.O.S. 15. Regulatory information All of the components in the product are on the following Inventory lists: X = listed International Inventories Component TSCA DSL NDSL EINECS ELINCS NLP PICCS ENCS AICS IECSC KECL Pyridinium, cetyl-, chloride X X X X - monohydrate Pyridinium, 1-hexadecyl-, X X X X X X - chloride Legend: X - Listed E - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA. F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA. N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used. P - Indicates a commenced PMN substance R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA. S - Indicates a substance that is identified in a proposed or final Significant New Use Rule T - Indicates a substance that is the subject of a Section 4 test rule under TSCA. XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base Production and Site Reports (40 CFR 710(B). Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater. Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants that comprises one of the eligibility criteria for the exemption rule. U.S. Federal Regulations TSCA 12(b) Page 6 / 7

7 SARA 313 SARA 311/312 Hazard Categories CWA (Clean Water Act) Clean Air Act See section 2 for more information OSHA Occupational Safety and Health Administration CERCLA California Proposition 65 U.S. State Right-to-Know Regulations This product does not contain any Proposition 65 chemicals U.S. Department of Transportation Reportable Quantity (RQ): DOT Marine Pollutant DOT Severe Marine Pollutant N N N U.S. Department of Homeland Security This product does not contain any DHS chemicals. Other International Regulations Mexico - Grade Prepared By Creation Date Revision Date Print Date Revision Summary 16. Other information Regulatory Affairs Thermo Fisher Scientific EMSDS.RA@thermofisher.com 08-Jan Jan Jan-2018 This document has been updated to comply with the US OSHA HazCom 2012 Standard replacing the current legislation under 29 CFR to align with the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text End of SDS Page 7 / 7