SAFETY DATA SHEET. Creation Date 04-September-2009 Revision Date 11-April-2018 Revision Number Identification

Transcription

1 SAFETY DATA SHEET Creation Date 04-September-2009 Revision Number 5 Product Name Cat No. : 1. Identification Citric acid monohydrate A104-3; A104-3LC; A104-10; A104-10LC; A LB; A ; A110-3; A110-10; A110-10LC; A110-50; A ; A111-12; A ; A111SAM-1; A111SAM-2; A111SAM-3 CAS-No Synonyms (Granular/Crystalline/Certified ACS/USP/EP/BP/JP) Recommended Use Uses advised against Laboratory chemicals. Food, drug, pesticide or biocidal product use Details of the supplier of the safety data sheet Company Importer/Distributor Fisher Scientific 112 Colonnade Road, Ottawa, ON K2E 7L6, Canada Tel: Manufacturer Fisher Scientific One Reagent Lane Fair Lawn, NJ Tel: (201) Emergency Telephone Number CHEMTRECÒ, Inside the USA: CHEMTRECÒ, Outside the USA: Classification WHMIS 2015 Classification 2. Hazard(s) identification Classified as hazardous under the Hazardous Products Regulations (SOR/ ) Serious Eye Damage/Eye Irritation Category 2 Specific target organ toxicity (single exposure) Category 3 Target Organs - Respiratory system. Combustible Dusts Category 1 Label Elements Signal Word Warning Hazard Statements May form combustible dust concentrations in air Causes serious eye irritation May cause respiratory irritation Page 1 / 6

2 Precautionary Statements Prevention Keep container tightly closed Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking Wash face, hands and any exposed skin thoroughly after handling Wear eye/face protection Response In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing If eye irritation persists: Get medical advice/attention Storage Store in a well-ventilated place. Keep container tightly closed Disposal Dispose of contents/container to an approved waste disposal plant 3. Composition/Information on Ingredients Component CAS-No Weight % Citric acid monohydrate >95 Citric acid First-aid measures Eye Contact Skin Contact Inhalation Ingestion Most important symptoms/effects Notes to Physician Suitable Extinguishing Media Unsuitable Extinguishing Media Flash Point Method - Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. Wash off immediately with plenty of water for at least 15 minutes. Get medical attention if symptoms occur. Move to fresh air. Get medical attention if symptoms occur. If not breathing, give artificial respiration. Do not induce vomiting. Obtain medical attention.. Treat symptomatically 5. Fire-fighting measures Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Autoignition Temperature 345 C / 653 F Explosion Limits Page 2 / 6

3 Upper Lower Oxidizing Properties Not oxidising Sensitivity to Mechanical Impact Sensitivity to Static Discharge Specific Hazards Arising from the Chemical Dust can form an explosive mixture in air. Keep product and empty container away from heat and sources of ignition. Fine dust dispersed in air may ignite. Hazardous Combustion Products Carbon monoxide (CO) Carbon dioxide (CO2) Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors. NFPA Health 2 Flammability 1 Instability 0 Physical hazards N/A Personal Precautions Environmental Precautions 6. Accidental release measures Ensure adequate ventilation. Use personal protective equipment. Avoid dust formation. Should not be released into the environment. See Section 12 for additional ecological information. Methods for Containment and Clean Sweep up or vacuum up spillage and collect in suitable container for disposal. Avoid dust Up formation. Handling Storage Exposure Guidelines 7. Handling and storage Wear personal protective equipment. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Avoid dust formation. Keep containers tightly closed in a dry, cool and well-ventilated place. 8. Exposure controls / personal protection This product does not contain any hazardous materials with occupational exposure limitsestablished by the region specific regulatory bodies. Engineering Measures Ensure that eyewash stations and safety showers are close to the workstation location. Ensure adequate ventilation, especially in confined areas. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source Personal protective equipment Eye Protection Hand Protection Goggles Wear appropriate protective gloves and clothing to prevent skin exposure. Glove material Breakthrough time Glove thickness Glove comments Natural rubber Nitrile rubber Neoprene PVC See manufacturers recommendations Splash protection only Page 3 / 6

4 Butyl rubber - Inspect gloves before use. observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information) gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. gloves with care avoiding skin contamination. Respiratory Protection When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. Follow the OSHA respirator regulations found in 29 CFR or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly Recommended Filter type: Particulates filter conforming to EN 143 When RPE is used a face piece Fit Test should be conducted Environmental exposure controls. Hygiene Measures Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing before re-use. Wash hands before breaks and at the end of workday. 9. Physical and chemical properties Physical State Solid Appearance White Odor Odorless Odor Threshold ph g/L (20 C) Melting Point/Range C / F Boiling Point/Range Flash Point Evaporation Rate Not applicable Flammability (solid,gas) Flammability or explosive limits Upper Lower Vapor Pressure Vapor Density Not applicable Density 1.54 g/cm3 (20 C) Specific Gravity Bulk Density kg/m 3 (20 C) Solubility Soluble in water Partition coefficient; n-octanol/water Autoignition Temperature 345 C / 653 F Decomposition Temperature > 170 C Viscosity Not applicable Molecular Formula C6 H8 O7. H2 O Molecular Weight Stability and reactivity Reactive Hazard Stability Conditions to Avoid None known, based on information available Stable under normal conditions. Incompatible products. Excess heat. Temperatures above 170 C. Avoid dust formation. Page 4 / 6

5 Incompatible Materials Strong oxidizing agents, Strong bases Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2) Hazardous Polymerization Hazardous Reactions Acute Toxicity Hazardous polymerization does not occur. None under normal processing. 11. Toxicological information Product Information LD50 Oral VALUE 11,700 mg/kg (rat) Component Information Component LD50 Oral LD50 Dermal LC50 Inhalation Citric acid monohydrate 5.79 g/kg ( Mouse ) Not listed Not listed Citric acid LD50 = 3 g/kg ( Rat ) LD50 = 3000 mg/kg ( Rat ) >2 g/kg ( Rat ) Not listed Toxicologically Synergistic Products Delayed and immediate effects as well as chronic effects from short and long-term exposure Irritation Sensitization Carcinogenicity Severe eye irritant; The table below indicates whether each agency has listed any ingredient as a carcinogen. Component CAS-No IARC NTP ACGIH OSHA Mexico Citric acid Not listed Not listed Not listed Not listed Not listed monohydrate Citric acid Not listed Not listed Not listed Not listed Not listed Mutagenic Effects Reproductive Effects Developmental Effects Teratogenicity STOT - single exposure STOT - repeated exposure Aspiration hazard Symptoms / effects,both acute and delayed Endocrine Disruptor Information Other Adverse Effects Ecotoxicity Do not empty into drains..... Respiratory system None known The toxicological properties have not been fully investigated. 12. Ecological information Component Freshwater Algae Freshwater Fish Microtox Water Flea Citric acid Not listed Leuciscus idus: LC50 = Photobacterium EC50 = 120 mg/l/72h mg/l/96h phosphoreum: EC50 = 14 Page 5 / 6

6 mg/l/15 min Persistence and Degradability Bioaccumulation/ Accumulation Mobility Persistence is unlikely.. Will likely be mobile in the environment due to its water solubility. Component log Pow Citric acid monohydrate Citric acid Waste Disposal Methods DOT TDG IATA IMDG/IMO 13. Disposal considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. 14. Transport information 15. Regulatory information International Inventories Component DSL NDSL TSCA EINECS ELINCS NLP PICCS ENCS AICS IECSC KECL Citric acid monohydrate X X X X X - Citric acid X - X X X X X X Canada SDS in compliance with provisions of information as set out in Canadian Standard - Part 4, Schedule 1 and 2 of the Hazardous Products Regulations (HPR) and meets the requirements of the HPR (Paragraph 13(1)(a) of the Hazardous Products Act (HPA)). Prepared By Creation Date Revision Date Print Date Revision Summary 16. Other information Regulatory Affairs Thermo Fisher Scientific EMSDS.RA@thermofisher.com 04-September April April-2018 This document has been updated to comply with the requirements of WHMIS 2015 to align with the Globally Harmonised System (GHS) for the Classification and Labelling of Chemicals. Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text End of SDS Page 6 / 6