Pimpinella anisum RNA/DNA. Anethole. Methyl chavicol. Townsend and. Anderson Pimpinella anisum Umbelliferae. Davis & Bauman.

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1 Pimpinella anisum 255 / Townsend and Anethole Methyl chavicol 2 Guest Anderson Davis & uman 5 Pimpinella anisum Umbelliferae uman & 2 Currie 2

2 5 Bell Ling et. al. Gluconeogenesis 2 22 Teitz Kirby 2 5 Harbone 2 Maniatis et. al. C 5 2 Scheifler Student t - test One way analysis of Least significant variance difference (LSD) 3 T 255 P<.5

3 P<.5 P<.5 P<.5 P>.5 P>.5 P>.5 P<.5 P<.5 P>.5 3 P<.5 P<.5 P<.5 P>.5 P>.5 P<.5 P<.5 P<.5 P>.5 P>.5

4 3 255 C C T T C C T T P<.5 P< C C T T C C T T P<.5 P<.5

5 3 255 C C T T Bb Bb Bb C C T T P<.5 P<.5 Larson,985 Bell 5 Tucker Scheffeild Linzell Mammotropic hormones Philipson 2

6 Placental lactogen Zhao et. al. Munford Greenbaun 5 Slater Dunshea et. al. Zhao et. al. 5 Hacker Li Dunshea et. al. Posner et. al. References Pimpinella anisum 5

7 Li, S.; & Hacker, R. R. (995). The effect of caffeine on mammary gland development and milk yield in primiparous sows. J. Anim. Sci., 73: 53. Ling, P. R.; Bistrian, B. R.; Blackburn, G. L.; & Istfan, N. (987). Effect of fetal growth on maternal protein metabolism in postabsorptive rat. Am. J. Phsiol., 252: E38. Linzell, J. L. (97). Mammary blood flow and methodsof identifying and measuring precursors of milk. In: Lactation: A comprehensive treatise. Vol., by: B. L. Larson and V. R. Smith (eds.). Acad. Press, New York, N.Y., P: 26. Maniatis, T.; Fritsch, E. F.; & Sambrook, J. (982). Molecular Cloning: A Laboratory Manual. Coldspring Harbor Laboratory. Munford, R. E. (96). A review of anatomical and biochemical changes in the mammary gland with particular references to quantitative methods of assesing mammary development. Dairy Sci. str., 26(7): 293. Philipson, A. T.; & Pritchard, W. R. (98). Scientific Foundation of Veterinary Medicine. Heinemann, W., Medical Books Limt., London. Posner, B. I.; Killy, P. A.; & Friesen, H. G. (97). Induction of a lactogenic receptor in rat liver: Influence of estrogen on the pituitary. Pro. Nat. Acad. Sci. (USA), 7: 27. Scheffield, L. G. (99). Caffeine administered during pregnancy augments subsequent lactation in mice. J. Anim. Sci., 69: 28. Scheifler, W. C. (98). Statistics for the Biological Science. 2 nd ed., Addison-Wesley Publ. Comp., California, London. Tietz, N. W. (97). Fundamentals of Clinical Chemistry. W. B. Saunders Company. Philadelphia, London. P: 5, 68, 352. Townsend, C. C.; & Guest, E. (98). Flora of Iraq. Vol., Part. Anderson, R.R. (97). Endocrinological control. In: Lactation: A comprehensive treatise. Vol. I, by: B. L. Larson and V. R. Smith (eds.). Acad. Press, New York, N.Y., P: 97-. uman, D. E.; & Currie, W. B. (98). Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis. J. Dairy Sci., 63: 5. Bell, A. W. (995). Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. J. Anim. Sci., 73:28. Davis, C. L.; & uman, D. E. (97). General metabolism associated with the synthesis of milk. In: Lactation: A comprehensive treatise. Vol. II, by: B. L. Larson and V. R. Smith (eds.). Acad. Press, New York, N.Y., P:. Dunshea, F. R.; uman, D. E.; Boyd, R. D.; & Bell, A. W. (992). Temporal response of circulating metabolism and hormones during somatotrpin treatment of growing pigs. J. Anim. Sci., 7: 23. Greenbaum, A. L.; & Slater, T. F. (957). Studies on the particulate components of the rat mammary gland. Biochem. J., 66: 55. Harborne, J. B.; Mabray, T. J.; & Mabray, H. (975). Physiology and Function of Flavonoids. P: The Flavoids. Acad. Press, New York, San Francisco. Kirby, K. S. (957). A new method for the isolation of deoxyribonucleic acid: evidence on the nature of bonds between ribonucleic acid and protein. Biochem. J., 66: 95. Larson, B. L. (985). Biosynthesis and cellular secretion of milk. In: Lactation. B. L. Larson (ed.). The Iowa State Univ. Press, Ames.

8 Zhao, A. P. (996). Regulation of glucose transport gene expression in mammary gland, muscle, and liver of lactating cows by administration of bovine growth hormone and growth hormone releasing factor. J. Anim. Sci., 7: 83. Ministry of Agriculture & Agrarian Reform. ghdad-iraq. P: 7, 9. Tucker, H. A. (987). Quantitative estimates of mammary growth during various physiological states: a review. J. Dairy Sci., 7: 958. Effect of Pimpinella anisum extract on some biochemical components of blood and mammary glands in mammals Dr. Jabbar bas Ahmed Al-Sa aidi College of Vet. Med./ Univ. Al-Qadisiya stract This experiment was carried out to determine the effect of aniseed administration on some biochemical concentrations of blood serum and mammary tissues in pregnant rats during pregnancy and lactation.fourty primiparous pregnant female rats were randomly divided into two equal groups: a control group were administered drinking water and a treated group were administered the aqueous solution of aniseed alcoholic 7% extract (.52 mg/kg B.Wt.).After parturition, ten animals from each group were randomly isolated. Blood and mammary tissue samples, were obtained for biochemical evaluation, while, the remaining animals were allowed to suckle their litters for the first eleven days of lactational period, and then, blood and mammary tissue samples, were obtained for the same purpose above.results of the st day after parturition showed that treatment caused a significant increase in serum glucose and total protein, a significant decrease in serum cholesterol, a nonsignificant increase in mammary glucose and total cholesterol, and a significant increase in mammary total protein. While, results of the th day of lactational period showed a significant increase of previous parameters in mammary tissues at the th day of lactational period and there was no changes observed at the st day. From the other hand, results of nucleic acid concentrations, revealed that aniseed extract lead to a significant increase in concentrations at the th day, concentrations at the st and th days, / ratio at the th day.it was concluded that aniseed extract administration during pregnancy leads to an increase of precursors of milk in blood, as well as mammary tissue performance for utilization of these precursors.

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