GI Disease INTEGRATING ALTERNATIVE THERAPIES FOR IMPROVED CLINICAL OUTCOMES

Transcription

1 GI Disease INTEGRATING ALTERNATIVE THERAPIES FOR IMPROVED CLINICAL OUTCOMES

2 Digestive Enzymes

3 Digestive Enzymes Digestive system absorbs nutrients. Food has to be broken down into its nutrient pieces: amino acids (from proteins), fatty acids and cholesterol (from fats), and simple sugars (from carbohydrates), + vitamins, minerals, etc. If we don t have enough digestive enzymes, we can t break down our food DE come from food or the GI tract

4

5 Digestive Enzymes Saliva- carbohydrases (amylase) Not in the wild Stomach- proteases (pepsin) Pancreas- lipases (which break down fats) Further break down of carbohydrates and proteins Small intestines Digestion should be complete to single molecules

6 Enzymes Feed your pet enzymes with her meals, they aid in digestion. When you feed the exact same enzymes at other times, they work systemically for metabolic purposes.

7 Enzymes away from meals Support the healthy circulation of blood Maintaining normal immune function Clear cellular debris while cleansing tissue Stimulate healthy new cell growth Promote normal cell growth Promote a healthy immune response Support normal detoxification processes Clear away undigested proteins, cleansing the lymph and blood

8 The Best Digestive Enzymes to Feed Animal based Pancreatic supplements EPI Fungal based Aspirgillus niger Survive in a wide range of ph Allergies Plant based

9 When to Recommend Digestive Enzymes Exocrine pancreatic insufficiency (EPI), pancreatic hypoplasia, and pancreatitis, diabetes Inflammatory bowel disease (particularly lymphocytic-plasmacytic gastroenteritis) may impact the production and/or release of digestive enzymes Immune compromise Animals on processed food or kibble Chronic diarrhea

10 Benefits of Digestive Enzymes Saves clients $ pets will be getting more nutrition from the same food, they may be able to feed less, Reduces the amount of stool because less food is wasted through improper digestion. Improves the quality of the stool. Makes pets feel more satiated, which can reduce begging. Makes pets healthier because they are getting more of the nutrition they need.

11 Bromelain in Inflammation Proteolytic enzyme bromelain, from pineapple, reduce inflammation from infection and injuries. The University of Maryland suggests that bromelain can be used to decrease swelling, bruising, healing time and pain after surgery and physical injuries, such as tendinitis, sprains and strains, and other minor muscle injuries. In Europe, bromelain is used to treat sinus and nasal swelling following ear, nose and throat surgery or trauma. The dose for this special use is 50 mg to 100 mg per ten pounds of body weight, divided into two doses; mix with cool water and administer orally for up to ten days.

12 Which enzymes to choose for GI supplement At a minimum protease, lipase and amylase Many also look for cellulase, which is useful if the food contains fibrous vegetables or grains

13 Probiotics

14

15 Probiotics Live microorganisms that provide health benefits when consumed Primarily bacteria but can be yeast Many types but most Lactobacillus (upper GI) Bifidobacterium (lower GI)

16 Probiotics Overall gastrointestinal maintenance and health Faster promotion of gut health Defense from emotional and physiological stressors Support for pets in less-than-optimal health, such as runts, and shelter animals

17 Probiotics Widely recognized to help in cases of IBS IBD Infectious diarrhea (from bacteria, viruses or parasites) Antibiotic related diarrhea Separate from antibiotics Consider for chronic or recurrent UTI- some studies in people

18 How do they work? Probiotic "good" bacteria lower intestinal ph Helps boost their own numbers Lowers the numbers of disease-causing bacteria Produce SCFA which make it harder for potentially disease-causing pathogens to set up shop

19 How can they help? boosting poor immune function addressing bacterial imbalance enhancing the health of the cells in the tissue of the GI tract help with digestion by providing their own digestive enzymes

20 Dosing Human products- give full adult dose for lb dog To help with digestion, probiotics should be taken with meals Otherwise they may survive better if given between meals, particularly if taken with liquid that helps to dilute stomach acid and move them more quickly into the digestive tract

21 Probiotics Studies indicate that multi-strain high innoculates (1-10 billion CFU) work best Does not need to be from host species to be effective Controversial as to value of live organisms

22 Preventative and therapeutic probiotic use in allergic skin conditions: experimental and clinical findings. Biomed Res Int. January 2013;2013(0): Clinical improvement especially in IgE-sensitized eczema and experimental models such as atopic dermatitis-like lesions (trinitrochlorobenzene and picryl chloride sensitizations) and allergic contact dermatitis (dinitrofluorobenzene sensitization) has been reported. Although there is a very promising evidence to recommend the addition of probiotics into foods, probiotics do not have a proven role in the prevention or the therapy of allergic skin disorders. Thus, being aware of possible measures, such as probiotics use, to prevent/heal atopic diseases is essential for the practicing allergy specialist.

23 Prebiotics

24 Prebiotics A nondigestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the gut and thus improves host health Fructooligosaccharides (FOS) are the most common

25 Prebiotics Provide food for the bugs Can be used alone to fortify endogenous probiotics or enhance exogenous probiotics Soluble fiber Found in many plants and herbs Sources include inulin (a form of FOS extracted from chicory), larch (a source of arabinogalactins), pectins, beet pulp, gums (such as guar gum), and wheat dextrin

26 When to Recommend Prebiotics Immunosuppression Digestive disorders- chronic diarrhea Following antibiotic therapy Studies done on rats show that prebiotics may help correct hyperlipidemia

27 Other Useful Therapies

28 Montmorillonite Clay Calciuim Aluminosilicate (CAS) Silica sheets adsorb Toxins Inflammatory cytokines Endotoxins Aflatoxins Chemotherapy biproducts

29 Montmorillonite Clay Increases mucopolysaccharide 2 which provides mucus protection to bowel mucosa epithelial cells Does not interfere with nutrient or drug absorbtion Study in dogs showed 65-85% improvement in intractable diarrhea where conventional therapies failed (metronidazole, tylosin, etc) Good for acute and chronic diarrhea

30 Rice water fast Congee Cook 1 cup white rice with 3-4 cups water until water is creamy Strain the rice Water opens the Chloride channels Sodium will follow the Chloride Water will follow that Blend with chicken baby food for taste if needed Good for acute and chronic diarrhea

31 Fasting Principles Feed substantially less food while having diarrhea! Use binding, soluble fiber foods like white rice, pumpkin, sweet potato or squash Keep it simple with bland, easy-to-digest protein sources like eggs and/or cooked chicken

32 Micro-biome Restorative Therapy The Power of Poop IBD Chronic Diarrhea Clostridium Giardia

33 Fecal Transplant Considerations Donor choice important Improve the microclimate of the gut Pre and probiotics, fresh foods, colostrum Remove the recipient s Biofilm Conventionally antibiotics Dose orally and/or rectally

34 Single Useful Herbs for GI

35 Cat s Claw Anti-inflammatory Anti-diarrheal IBD POA (anti-inflammatory alkaloid) vs TOA (proinflammatory) Look for a product with TOA in the single digits

36 Ginger root Good for vomiting or diarrhea Tea for acute vomiting May be too warming for some situations Anti-inflammatory Regulates peristalsis Can increase appetite

37 Ginger Root Tea 1/2 teaspoon dried ginger root or grated fresh ginger steeped in 6 oz hot water for 10 minutes, strain and administer PO in 1-3 cc amounts for smaller patients and 3-6 cc amounts for larger patients Can give by retention enema if patient can not tolerate PO

38 Marshmallow IBD Indigestion Acute vomiting Ulcers Straining to defecate Leaky gut Mucilage-coats the stomach lining Best as combination of root and leaves

39 Slippery Elm Bark Mucilage Reflux Ulcerative colitis IBS Diarrhea Use in old and debilitated patients Be careful of sourcing (marshmallow is alternative)