MARY-FRANCES O CONNOR CURRICULUM VITAE

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1 MARY-FRANCES O CONNOR CURRICULUM VITAE ACADEMIC POSITION 2012-present Assistant Professor, Department of Psychology University of Arizona, Tucson, Arizona EDUCATION Bachelor of Arts, Psychology Northwestern University, Evanston, Illinois Doctoral Degree, Clinical Psychology University of Arizona, Tucson, Arizona Clinical Internship Neuropsychiatric Institute and Hospital University of California, Los Angeles, California Post-Doctoral Fellowship UCLA Cousins Center for Psychoneuroimmunology University of California, Los Angeles, California Assistant Professor, UCLA Cousins Center for Psychoneuroimmunology Semel Institute for Neuroscience and Human Behavior University of California, Los Angeles LICENSURE January 2006 California License PSY20680 RESEARCH PAPERS - PEER REVIEWED Weber, J.T., O Connor, M.-F., Hayataka, K., Colson, N., Medora, R., Russo, E.B., & Parker, K.K. (1997). Activity of parthenolide at 5-HT2A receptors. Journal of Natural Products, 60, Weber, J.T., Hayataka, K., O Connor, M.-F., and Parker, K.K. (1997). Rabbit cerebral cortex 5HT1a receptors. Comparative Biochemistry and Physiology, 117C, Hayataka, K., O Connor, M.-F., Kinzler, N., Weber, J.T., & Parker, K.K. (1998). A bioactive peptide form the transmembrane 5-intracellular loop 3 region of the human 5- HT1A receptor. Biochemistry and Cell Biology, 76, O Connor, M.-F., Allen, J.J.B., & Kaszniak, A.W. (2002) Autonomic and emotion regulation in bereavement and depression. Journal of Psychosomatic Research, 52,

2 O Connor, M.-F. (2002). Making meaning of life events: Theory, evidence and research directions for an alternative model. Omega: Journal of Death and Dying, 46, Gündel, H., O Connor, M.-F., Littrell, L., Fort, C., & Lane, R. (2003). Functional neuroanatomy of grief: An fmri study. American Journal of Psychiatry, 160, O Connor, M.-F. (2004). Finding boundaries inside prison walls: Case study of a terminally ill inmate. Death Studies, 28, O Connor, M.-F., Allen, J.J.B., & Kaszniak, A.W. (2005). Emotional disclosure for whom? The role of vagal tone in bereavement. Biological Psychology, 68, O Connor, M.-F. (2005). Bereavement and the brain: Invitation to a conversation between bereavement researchers and neuroscientists. Death Studies, 29, O Connor, M.-F., Irwin, M., Seldon, J., Kwan, L., Ganz, P.A. (2007). Pro-inflammatory cytokines and depression in a familial cancer registry. Psycho-Oncology, 16, O Connor, M.-F., Motivala, S., Valladares, E.M., Olmstead, R. and Irwin, M. (2007). Sex differences in monocyte expression of IL-6: Role of autonomic mechanisms. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 293, R O Connor, M.-F., Gündel, H., McRae, K., Lane, R.D. (2007). Baseline vagal tone predicts BOLD response during elicitation of grief. Neuropsychopharmacology, 32, O Connor, M.-F., Wellisch, D.K., Stanton, A.L., Eisenberger, N.I., Irwin, M.R., Lieberman, M.D. (2008). Craving love? Complicated grief activates brain s reward center. NeuroImage, 42, PMC[ ]. Buchheim, A., George, C., Gündel, H., Heinrichs, M., Koops, E., O Connor, M.-F., Pokorny, D. (2009). Oxytocin enhances the experience of attachment security. Psychoneuroendocrinology, 34, O Connor, M.-F., Wellisch, D.K., Irwin, M. (2009). When grief heats up: Proinflammatory cytokines predict regional brain activation. NeuroImage, 47, PMC[ ]. O Connor, M.-F., Bower, J., *Cho, H.J., *Creswell, J.D., *Hoyt, M.A., Martin, J.L., Robles, T., Sloan, E., *Thomas, K.S., Irwin, M. (2009). To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers. Brain, Behavior and Immunity, 23, PMC[ ]. O Connor, M-F., Irwin, M.R. (2010). Links between behavioral factors and inflammation. Clinical Pharamacology and Therapeutics, 87, PMC[ ]. 2

3 Gold, S.M., Kern, K.C., O'Connor, M.-F., Montag, M.J., Kim, A., Yoo, Y.S., Giesser, B.S., Sicotte, N.L. (2010). Smaller Cornu Ammonis 2 3/Dentate Gyrus Volumes and Elevated Cortisol in Multiple Sclerosis Patients with Depressive Symptoms. Biological Psychiatry, 68, [PMID: ] Shear, M.K., Duan, N., Reynolds, C., Simon, N., Zisook, S., Lebowitz, B., Sung, S., Guesquierre, A., Gorscak, B., Clayton, P., Ito, M., Nakajima, S., Konishi, T., Brent, D., Melhem, N., Meert, K., Schiff, M., Neimeyer, R., O Connor, M.-F., First, M., Sareen, J., Bolton, J., Skritskaya, N., Mancini, A. (2011). Complicated Grief and related bereavement issues for DSM- 5. Depression and Anxiety, 28, O Connor, M.-F., Wellisch, D. K., Stanton, A. L., Olmstead, R., & Irwin, M. R. (2012). Diurnal cortisol in Complicated and Non-Complicated Grief: Slope differences across the day. Psychoneuroendocrinology, 37, PMC[ ]. O Connor, M.-F. (2012). Immunological and neuroimaging biomarkers of Complicated Grief Dialogues in Clinical Neuroscience, 14 (in press). Gold, S.M., O'Connor, M.-F., Sicotte, N.L. Detection of altered hippocampal morphology in multiple sclerosis-associated depression using automated surface mesh modeling. Human Brain Mapping (in press). *Schultze-Florey, C.R., Martínez-Maza, O., Magpantay, L., Breen, E.C., Irwin, M.R., Gündel, H., O Connor, M.-F. When grief makes you sick: Bereavement induced systemic inflammation is a question of genotype. Brain, Behavior, and Immunity (in press). *student of M.-F. O Connor BOOK CHAPTERS Gianaros, P. J., & O'Connor, M.-F. (2010). Neuroimaging Methods in Stress Science. In R. J. Contrada & A. Baum (Eds.), Handbook of stress science: Biology, psychology, and health (pp ). New York: Springer. O'Connor, M.-F. (2011). Physiological mechanisms and the neurobiology of Complicated Grief. In M. Stroebe, H. Schut, J. van den Bout & P. Boelen (Eds.), Complicated Grief: Scientific Foundations for Health Care Professionals. London: Routledge. INVITED PRESENTATIONS O Connor, M.-F. (November, 2003). The neurobiology of bereavement. Paper presented at the Neurobiology and Psychosomatics Congress, University of Munich, Germany. O Connor, M.-F. (September, 2004). The neurobiology of grief. Paper presented at the University of Montana, Missoula, Montana. 3

4 O Connor, M.-F. (February, 2005). The neurobiology of grief. Paper presented at the Health Psychology Colloquia, University of California, Los Angeles, Los Angeles, California. O Connor, M.-F. (October, 2006). Complicated Grief: Physiology and Phenomenology. Harbor-UCLA Medical Center Grand Rounds, Los Angeles, California. O Connor, M.-F. (April, 2007). Complicated Grief: Physiology and Phenomenology. Psychiatry Grand Rounds at the Semel Institute, UCLA Medical Center, Los Angeles, California. O Connor, M.-F. (October, 2007). Understanding complicated grief. UCLA 12 th Annual Review of Psychiatry, UCLA Medical Center, Los Angeles, California. O Connor, M.-F. (November, 2008). Complicated Grief: Physiology and Phenomenology. University of Minnesota, Twin Cities, Minnesota. O Connor, M.-F. (November, 2008). Complicated Grief: Physiology and Phenomenology. Hamilton College, Clinton, New York. O Connor, M.-F. (December, 2008). Complicated Grief: Physiology and Phenomenology. University of Ohio, Columbus, Ohio. O Connor, M.-F. (May, 2009). Los Angeles County Department of Mental Health Clinical Leadership Forum at UCLA, Los Angeles, CA O Connor, M.-F. (February, 2010). Grief in families affected by cancer: A biopsychosocial approach. University of North Carolina, Chapel Hill, North Carolina. O Connor, M.-F. (October, 2010). Grief, pain and reward pathways. California Society of Addiction Medicine Review Course. Newport Beach, California. O Connor, M.-F. (April, 2011). Complicated Grief: What s the brain got to do with it? University of Arizona, Tucson, Arizona. O Connor, M.-F. (May, 2011). A social and affective neuroscience perspective on grief and adaptation to loss. University of California, Santa Barbara, Santa Barbara, California. O Connor, M.-F. (August, 2011). Complicated Grief: Significant Findings from Recent Clinical and Neurobiological Research. Hospice of Santa Barbara, Santa Barbara, California. SELECTED PUBLISHED ABSTRACTS AND PRESENTATIONS O Connor, M.-F., Allen, J.J.B., & Kaszniak, A.W. (March, 2001). The heart of bereavement: Autonomic and emotion regulation in depressed and bereaved groups. Poster presented at the American Psychosomatic Society, Monterey, California. 4

5 O Connor, M.-F., Allen, J.J.B., & Kaszniak, A.W. (2002). Self-regulation and positive emotion in bereavement. Psychophysiology, 39, S62. O Connor, M.-F., Allen, J.J.B., & Kaszniak, A.W. (2003). Bereavement physiology and flight from intervention. Psychosomatic Medicine, 65, A80. O Connor, M.-F. (2004). Eliciting grief in the scanner: Emotion covariates of brain activation. Psychophysiology, 41, S74. O Connor, M.-F. (2004). Emotional awareness of self and others as predictors of autonomic arousal during bereavement. Psychophysiology, 41, S48. O Connor, M.-F. (March, 2005). Functional neuroanatomical correlates of emotional arousal during grief. Paper presented at the American Psychosomatic Society, Vancouver, Canada. O Connor, M.-F. (November, 2006). An fmri study comparing complicated and noncomplicated grief. International Society for the Study of Traumatic Stress, Hollywood, California. O Connor, M.-F. (March, 2007). Neural underpinnings of cardiovascular vulnerability: Convergent evidence from neuroimaging. Paper presented at the American Psychosomatic Society, Budapest, Hungary. O Connor, M.-F. (September, 2007). Integrating regional brain activity and cortisol regulation in bereaved women at familial risk for breast cancer. Paper presented at the International Psycho-oncology Society, London, UK. O Connor, M.-F. (March, 2008). Neuroimaging and inflammation. Symposium presented at the American Psychosomatic Society, Baltimore, MD. O Connor, M.-F. (May, 2008). Proinflammatory cytokines associated with sacc activity during grief elicitation. Paper presented at the Psychoneuroimmunology Research Society, Madison, WI. O Connor, M.-F., Wellisch, D.K., Stanton, A.L. & Irwin, M.R. (2009). Association between complicated grief and diurnal cortisol slope. Psychosomatic Medicine, 70, A73. O Connor, M.-F. (June, 2009). Empirical evidence on bereaved survivors of cancer patients quality of life, regional brain activation and inflammatory markers. Paper presented at the International Psycho-oncology Society, Vienna, Austria. O Connor, M.-F., Gold, S.M., & Sicotte, N.L. (2010). Evidence for specific regions of hippocampal damage and cortisol elevation in multiple sclerosis patients with depressive symptoms. Psychosomatic Medicine, 73, E9. 5

6 O Connor, M.-F., & Shear, K. (2011). Biological mechanisms distinguishing depression and complicated grief: Circulating IL-6. Psychosomatic Medicine, 73, A124. O Connor, M.-F., *Schultze-Florey, C.R., Irwin, M.R., Martínez-Maza, O. (2012). A polymorphism in the oxytocin receptor gene is linked to avoidant attachment. Psychosomatic Medicine, 74, A6. O Connor, M.-F., *Schultze-Florey, C.R., Irwin, M.R., Martínez-Maza, O. (2012). Gene x environment: Bereavement influences on cellular inflammation. Psychosomatic Medicine, 74, A95. O Connor, M.-F., *Schultze-Florey, C.R., Irwin, M.R., Martínez-Maza, O. (2012). Gene x environment: Bereavement influences on cellular inflammation. Poster presented at the 24 th Association for Psychological Science Annual Convention (Chicago, IL). RESEARCH GRANTS AND FELLOWSHIPS RECEIVED 10IB-0048 (Wellisch) 7/01/04-12/31/05 California Breast Cancer Research Program $100,000 Psychobiological Concomitants of the Grief Response in Women at High Risk for Breast Cancer Role: Co-investigator Research Fellow 07/01/06-06/30/07 Friends of the Semel Institute, UCLA $35,000 K01 AG (O Connor) 07/01/07-06/30/12 NIH-NIA $107,750 annually Complicated Grief in Older Adults: Physiological Substrates of Emotion Regulation Role: Principal Investigator Rapid Grants Program 01/31/08-06/30/08 UCLA Older Americans Independence Center $10,000 Validation of Multiplex Analyses in the Inflammatory Biology Core Laboratory Role: Principal Investigator Research Services Funding Program 12/01/08-06/30/09 UCLA Older Americans Independence Center $10,000 Biomarkers in Older Adults Predicting Treatment Response in Complicated Grief Role: Principal Investigator ARRA Supplement--AG /01/09-08/30/11 NIH-NIA $99,180 annually Complicated Grief in Older Adults: Physiological Substrates of Emotion Regulation Role: Principal Investigator 6

7 Arizona Alzheimer s Disease Core 7/1/2012-6/30/2013 From 5P30AG NIH-NIA $29,006 A Randomized Controlled Trial of Virtual Reality Support Group for Alzheimer s Disease (AD) Caregivers This project compares a virtual online support group with an online text-based support group of caregivers. SELECTED MEDIA COVERAGE Conis, E. (July 7, 2008). 'Complicated grief' affects the brain differently. Los Angeles Times. Kim, J. (July 16, 2008). UCLA Study Links Extended Grief With Addiction, Reward Sensors. On NBC (NBC4 Los Angeles). Brannan, N. (July 17, 2008). Addicted to Grief? When time doesn't heal, the brain's reward system may be playing a role. Scientific American. Parry, V. (July 21, 2008). The pain of emotion. On BBC Radio 4. Parry, V. (July 26, 2008). Is pain all in the mind? The Times (London). Lu, A. (July 27, 2008). Why it's hard to say goodbye. ScienceNOW Daily News. Stein, R. (Aug 4, 2008). Unrelenting Grief May Be Sign of Distinct Syndrome. Washington Post. Adler, J. (August 4, 2008). Inside the grieving brain. Newsweek. Miller, K. (Aug 14, 2008). When grief won't go away. On Minnesota Public Radio. Schumer, F. (September 29, 2009). After a Death, the Pain That Doesn t Go Away. New York Times. Burger, K. (February, 2010). Die Sucht Nach Der Trauer. Bild Der Wissenschaft. HONORS AND SPECIAL AWARDS Association for Death Education and Counseling Richard Kalish Graduate Paper Award (2001) University of Arizona Graduate College Dissertation Small Grant Awardee (2002) Association for Death Education and Counseling Small Grant Awardee (2002) Changing Lives of Couples Data Workshop, Univ of Michigan, Scholarship Awardee (2002) University of California Office of the President Post-Doctoral Fellowship Alternate (2006) Psychoneuroimmunology Research Society Post-Doctoral Honoree (2006) NIH Loan Repayment Program Award (2005) Friends of the Semel Institute Junior Faculty Travel Grant (2006, 2008, 2009) 7

8 NIA and OBSSR honorarium and invitation to Opportunities for Advancing Behavioral and Social Science Research on Aging Workshop (2008) UCLA School of Medicine John H. Walsh Young Investigator Research Prize Nominee (2009) NSF/University of Arizona ADVANCE Junior Scientist Award (2010) RAND Summer Institute Workshop on Aging Invitee (2011) Advanced Research Institute in Geriatric Mental Health Scholar (2011, 2012) PROFESSIONAL AND SERVICE ACTIVITIES Fellowship Admissions Director, Cousins Center for PNI ( ) American Psychosomatic Society Annual Meeting Program Committee Member ( , 2011) Editor, Newsletter and Website ( ) Participant in Determining The Future Of The American Psychosomatic Society Long Range Planning Meeting (June, 2008) Representative to the Wolters Kluwer Health electronic platform meeting (June, 2009) Tweeting the Meeting at the American Psychosomatic Society Annual Meeting (March, 2012) Member American Psychosomatic Society Association for Psychological Science Psychoneuroimmunology Research Society Reviewer American Journal of Psychiatry Annals of Behavioral Medicine Annals of Oncology Biological Psychiatry Brain, Behavior and Immunity Comprehensive Psychiatry European Health Psychology Society Health Psychology Health Psychology Review Human Brain Mapping Journal of Clinical Oncology Neuroscience Neuroscience & Biobehavioral Reviews Physiology and Behavior Psychology and Health Psychophysiology Psychosomatic Medicine Social Cognitive and Affective Neuroscience Social Science and Medicine UCLA Multiple Sclerosis Achievement Center Neurological Services Educator ( ) 8

9 Segue Career Path Mentor for local high school students (2010) Lunch with a Scientist 8th Grade Science Class, Culver City Middle School, Culver City, California (2011) 9

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